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Treatment of Chronic Fatigue Syndrome: Findings, Principles and Strategies
Patrick Luyten,Boudewijn Van Houdenhove,Chi-Un Pae,Stefan Kempke,Peter Van Wambeke 대한신경정신의학회 2008 PSYCHIATRY INVESTIGATION Vol.5 No.4
Chronic fatigue syndrome (CFS) is a debilitating condition characterized by serious medically unexplained mental and physical fatigue. The high prevalence and both direct and indirect health costs of CFS patients represent a huge problem for contemporary health care. Moreover, the prognosis of CFS, even when treated, is often poor. In this paper, we first critically review current evidence based treatments of CFS. Second, we discuss the growing insights into the etiopathogenesis of CFS, and the need to translate and integrate these insights into future treatments. In particular, we formulate a pragmatic and empirically testable treatment approach, tailored to the individual needs of patients, which aims at restoring the mental and physical equilibrium of CFS patients by trying to bring about sustained life style changes. Chronic fatigue syndrome (CFS) is a debilitating condition characterized by serious medically unexplained mental and physical fatigue. The high prevalence and both direct and indirect health costs of CFS patients represent a huge problem for contemporary health care. Moreover, the prognosis of CFS, even when treated, is often poor. In this paper, we first critically review current evidence based treatments of CFS. Second, we discuss the growing insights into the etiopathogenesis of CFS, and the need to translate and integrate these insights into future treatments. In particular, we formulate a pragmatic and empirically testable treatment approach, tailored to the individual needs of patients, which aims at restoring the mental and physical equilibrium of CFS patients by trying to bring about sustained life style changes.
MBus: A Fully Synthesizable Low-power Portable Interconnect Bus for Millimeter-scale Sensor Systems
Lee, Inhee,Kuo, Ye-Sheng,Pannuto, Pat,Kim, Gyouho,Foo, Zhiyoong,Kempke, Ben,Jeong, Seokhyeon,Kim, Yejoong,Dutta, Prabal,Blaauw, David,Lee, Yoonmyung The Institute of Electronics and Information Engin 2016 Journal of semiconductor technology and science Vol.16 No.6
This paper presents a fully synthesizable low power interconnect bus for millimeter-scale wireless sensor nodes. A segmented ring bus topology minimizes the required chip real estate with low input/output pad count for ultra-small form factors. By avoiding the conventional open drain-based solution, the bus can be fully synthesizable. Low power is achieved by obviating a need for local oscillators in member nodes. Also, aggressive power gating allows low-power standby mode with only 53 gates powered on. An integrated wakeup scheme is compatible with a power management unit that has nW standby mode. A 3-module system including the bus is fabricated in a 180 nm process. The entire system consumes 8 nW in standby mode, and the bus achieves 17.5 pJ/bit/chip.
MBus : A Fully Synthesizable Low-power Portable Interconnect Bus for Millimeter-scale Sensor Systems
Inhee Lee,Ye-Sheng Kuo,Pat Pannuto,Gyouho Kim,Zhiyoong Foo,Ben Kempke,Seokhyeon Jeong,Yejoong Kim,Prabal Dutta,David Blaauw,Yoonmyung Lee 대한전자공학회 2016 Journal of semiconductor technology and science Vol.16 No.6
This paper presents a fully synthesizable low power interconnect bus for millimeter-scale wireless sensor nodes. A segmented ring bus topology minimizes the required chip real estate with low input/output pad count for ultra-small form factors. By avoiding the conventional open drain-based solution, the bus can be fully synthesizable. Low power is achieved by obviating a need for local oscillators in member nodes. Also, aggressive power gating allows low-power standby mode with only 53 gates powered on. An integrated wakeup scheme is compatible with a power management unit that has nW standby mode. A 3-module system including the bus is fabricated in a 180 nm process. The entire system consumes 8 nW in standby mode, and the bus achieves 17.5 pJ/bit/chip.