http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Kegong Fang (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
Textual properties of Cu–Mn mixed oxides and application for methyl formate synthesis from syngas
Haijun Zhao,Kegong Fang,Fang Dong,Minggui Lin,Yuhan Sun,Zhicheng Tang 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.54 No.-
Cu–Mn mixed oxides with different calcination temperatures were prepared using ammonia complexing method and evaluated for methyl formate (MF) synthesis from syngas with CaO–ZrO2 as co-catalyst. The influence of calcination temperature on the structure and properties of Cu–Mn mixed oxides was investigated by appropriate characterizations. Cu1.5Mn1.5O4 formed during the calcination of Cu–Mn catalyst at 450 C and played a significant role in the MF synthesis. However, it partially decomposed into CuO and MnO2 when the calcination temperature exceeded 550 C. Results showed that the optimum MF selectivity was obtained on Cu–Mn catalyst calcined at 450 C, and the highest CO conversion was obtained on the Cu–Mn sample with calcination temperature of 550 C. The reaction mechanism of MF synthesis from syngas over Cu–Mn mixed oxides and CaO–ZrO2 co-catalyst was thoroughly studied via typical model reactions, and the nucleophilic addition–elimination reaction mechanism was proposed.
-
Shanjie Wang,Kegong Chen,Ye Wang,Zeng Wang,Zhaoying Li,JunChen Guo,Jianfeng Chen,Wenhua Liu,Xiaohui Guo,Guangcan Yan,Chenchen Liang,Huai Yu,Shaohong Fang,Bo Yu 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00
Background Large-dose melatonin treatment in animal experiments was hardly translated into humans, which may explain the dilemma that the protective effects against myocardial injury in animal have been challenged by clinical trials. Ultrasound-targeted microbubble destruction (UTMD) has been considered a promising drug and gene delivery system to the target tissue. We aim to investigate whether cardiac gene delivery of melatonin receptor mediated by UTMD technology optimizes the efficacy of clinically equivalent dose of melatonin in sepsis-induced cardiomyopathy. Methods Melatonin and cardiac melatonin receptors in patients and rat models with lipopolysaccharide (LPS)- or cecal ligation and puncture (CLP)-induced sepsis were assessed. Rats received UTMD-mediated cardiac delivery of RORα/cationic microbubbles (CMBs) at 1, 3 and 5 days before CLP surgery. Echocardiography, histopathology and oxylipin metabolomics were assessed at 16–20 h after inducing fatal sepsis. Results We observed that patients with sepsis have lower serum melatonin than healthy controls, which was observed in the blood and hearts of Sprague–Dawley rat models with LPS- or CLP-induced sepsis. Notably, a mild dose (2.5 mg/kg) of intravenous melatonin did not substantially improve septic cardiomyopathy. We found decreased nuclear receptors RORα, not melatonin receptors MT1/2, under lethal sepsis that may weaken the potential benefits of a mild dose of melatonin treatment. In vivo, repeated UTMD-mediated cardiac delivery of RORα/CMBs exhibited favorable biosafety, efficiency and specificity, significantly strengthening the effects of a safe dose of melatonin on heart dysfunction and myocardial injury in septic rats. The cardiac delivery of RORα by UTMD technology and melatonin treatment improved mitochondrial dysfunction and oxylipin profiles, although there was no significant influence on systemic inflammation. Conclusions These findings provide new insights to explain the suboptimal effect of melatonin use in clinic and potential solutions to overcome the challenges. UTMD technology may be a promisingly interdisciplinary pattern against sepsis-induced cardiomyopathy.
-
Carbon dispersed iron-manganese catalyst for light olefin synthesis from CO hydrogenation
Jianli Zhang,Kegong Fang,Kan Zhang,Wenhuai Li,Yuhan Sun 한국화학공학회 2009 Korean Journal of Chemical Engineering Vol.26 No.3
High performance iron-manganese catalysts dispersed with carbon to produce light olefins from CO hydrogenation were prepared by sol-gel method using citric acid as precursor. The effects of carbon content on the bulk structure, the water gas shift reaction, the chain propagation ability and the activity and selectivity of the catalysts were investigated. The results showed that the catalysts were gradually reduced during the decomposition of the precursor when calcined under pure N2. The formation of iron-manganese mixed crystallites was favored and stabilized because of the enhanced interaction of iron and manganese with increasing carbon content. During the subsequent CO hydrogenation reaction, all the catalysts showed high activity and olefin selectivity. With increasing carbon content, the water gas shift (WGS) reaction was restrained and the chain propagation ability was inhibited. Catalysts with higher carbon content showed much lighter hydrocarbon products; however, the selectivity of CH4 was almost unchanged.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
