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( Kee-youn Yoo ) 한국화학공학회 2021 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.59 No.3
A kinetic model was developed for the dehydration of ethanol to ethylene based on two parallel reaction pathways. Kinetic parameters were estimated by fitting experimental data of powder catalysts in a lab-scale test, and the effectiveness factor was determined using data from pellet-type catalysts in bench-scale experiments. The developed model was used to design a multitubular fixed-bed reactor (MTR) and an adiabatic reactor (AR) at a 10 ton per day scale. The two different reactor types resulted in different process configurations: the MTR consumed the ethanol completely and did not produce the reaction intermediate, diethyl ether (DEE), resulting in simple separation trains at the expense of high equipment cost for the reactor, whereas the AR required azeotropic distillation and cryogenic distillation to recycle the unreacted ethanol and to separate the undesired DEE, respectively. Quantitative analysis based on the equipment and annual energy costs showed that, despite high equipment cost of the reactor, the MTR process had the advantages of high productivity and simple separation trains, whereas the use of additional separation trains in the AR process increased both the total equipment cost and the annual energy cost per unit production rate.
( Kee-youn Yoo ),( Hyunsik Yoon ) 한국화학공학회 2017 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.55 No.2
Heterogeneous semiconductor composites have been widely used to establish high-performance microelectronic or optoelectronic devices. During a deposition of silicon atoms on silicon/germanium compound surfaces, germanium (Ge) atoms are segregated from the substrate to the surface and are mixed in incoming a silicon layer. To suppress Ge segregation to obtain the interface sharpness between silicon layers and silicon/germanium composite layers, approaches have used silicon hydride gas species. The hydrogen atoms can play a role of inhibitors of silicon/germanium exchange. However, there are few kinetic models to explain the hydrogen effects. We propose using segregation probability which is affected by hydrogen atoms covering substrate surfaces. We derived the model to predict the segregation probability as well as the profile of Ge fraction through layers by using chemical reactions during silicon deposition.
Canonical Form and Mathematical Interpretation of Electrolyte Solution Systems
Yoo, Kee-Youn,He, Jiwen,Amundson, Neal R. 한국화학공학회 2004 Korean Journal of Chemical Engineering Vol.21 No.2
We describe a canonical form of electrolyte solution systems for the mathematical interpretation of solid-liquid equilibrium. The canonical form is obtained from the analysis of the algebraic structure of electrolyte solution systems and the Karush-Kuhn-Tucker(KKT)conditions for the minimization of the total Gibbs free energy. As a result, the mathematical role of solid species in the solid-liquid equilibrium problem is explained as a Lagrange multiplier of a sort of the linearly constrained optimization problem. This finding will add to the development of an efficient numerical algorithm for the simulation of electrolyte solution systems.
( Kee-youn Yoo ) 한국화학공학회 2017 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.55 No.1
Organic aerosols dispersed in the atmosphere likely undergo phase separation. Such internally mixed par-ticles are often described as comprising an organic phase and an aqueous phase separately. We studied the morphology of two liquid separated aerosols in the sub-microscale by using a simple thermodynamic model with Russian doll geom-etry. The morphology of particles can be easily predicted from the simple criteria on the surface tension and two alge-braic equations (the volume constraint and Young equation). This result may give the potential explanation about the complex morphology of the organic airborne particles
Kee, Youn Kyung,Park, Jung Tak,Yoon, Chang-Yun,Kim, Hyoungnae,Park, Seohyun,Yun, Hae Ryong,Jung, Su-Young,Jhee, Jong Hyun,Oh, Hyung Jung,Han, Seung Hyeok,Yoo, Tae-Hyun,Kang, Shin-Wook International Society for Peritoneal Dialysis 2017 Peritoneal dialysis international Vol.37 No.5
<P>Conclusion: Peritoneal dialysis can be considered as a long-term renal replacement therapy option, especially in non-diabetic, not overweight, and young ESRD patients.</P>
( Youn Kyung Kee ),( Tae Hyun Yoo ),( Seung Gyu Han ),( In Mee Han ),( Chang Yun Yoon ),( Eunyoung Lee ),( Young Su Joo ),( Jung Tak Park ),( Seung Hyeok Han ),( Beom Seok Kim ),( Shin Wook Kang ),( K 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Continuous renal replacement therapy (CRRT) has been widely used in critically ill acute kidney injury (AKI) patients. Moreover, some centers operate a specialized CRRT team (SCT) composed of physicians and nurses, but few studies have yet determined the superiority of SCT control. Methods: A total of 334 among 534 patients in original cohort, who started CRRT for severe AKI between August 2007 and September 2009 in Yonsei University Health System and were matched with a propensity score (PS), were divided into two groups based on SCT application. Moreover, we compared CRRT-related outcomes including down-time per day and lost time per filter-exchange between the two groups. The primary outcomes were 28- and 90-day all-cause mortality, and the secondary outcomes were the rates of renal function recovery at 28- and 90-day. Results: The down-time per day, lost time per filter-exchange, and RBC-transfused numbers during CRRT treatment were significantly lower after SCT approach compared with the group before SCT, while net ultrafiltration rate in after SCT group was significantly higher compared to the before SCT group. During the study period, the 28- and 90-day all-cause mortality rates were significantly decreased after SCT application. Cox regression analysis revealed that 28- and 90-day all-cause mortality rates were significantly lower under SCT control, after adjusting for primary diagnosis, emergent surgical cases, Charlson Comorbidity Index and biochemical parameters. However, there were no significant differences in the rate of renal function recovery before and after SCT approach in CRRT. Conclusions: A well-organized CRRT team could be beneficial for the clinical outcomes of AKI patients requiring CRRT.
Kee, Youn Kyung,Yoon, Chan-Yun,Kim, Seung Jun,Moon, Sung Jin,Kim, Chan Ho,Park, Jung Tak,Lim, Beom Jin,Chang, Tae Ik,Kang, Ea Wha,Kie, Jeong Hae,Yoo, Tae-Hyun,Jeong, Hyun Joo,Kang, Shin-Wook,Han, Seun Williams & Wilkins Co 2017 Medicine Vol.96 No.44
<▼1><P>Supplemental Digital Content is available in the text</P></▼1><▼2><P><B>Abstract</B></P><P>Proteinuria is a major determinant of adverse renal outcome, and its reduction slows renal progression in glomerular diseases. However, the optimal target of proteinuria in glomerular diseases is unclear, and discrepancies in the definition of proteinuria produce ambiguous findings. Here we investigated the optimal target of proteinuria by using different definitions of proteinuria. We analyzed 574 IgA nephropathy (IgAN), 175 membranous nephropathy (MGN), and 177 focal segmental glomerulosclerosis (FSGS) cases from 3 Korean kidney centers. We evaluated the impact of proteinuria on renal outcome with 2 definitions: time-average proteinuria (TAP) and time-varying proteinuria (TVP). The endpoint was renal progression, defined as a 50% decline in glomerular filtration rate or end-stage renal disease. During a median follow-up of 57.3 months, the primary outcome occurred in 54 patients with IgAN, 26 with MGN, and 30 with FSGS. Multivariate Cox regression using TAP indicated that there was a linear association between proteinuria and risk of renal progression in IgAN. However, moderate proteinuria was not associated with an increased risk of renal progression in MGN and FSGS. In contrast, the analysis by TVP showed that the risk significantly increased in proportion to proteinuria during follow-up in all 3 diseases. Our findings suggest that TVP-based model can delineate association between proteinuria and risk of renal progression better than TAP-based model, considering that TVP reflects the dynamic change of proteinuria over time. Thus, proteinuria reduction to the lowest possible level is required to improve renal outcomes in patients with glomerular diseases.</P></▼2>
이창연,오연희,임문환,유문집,박성기,김태우 동국대학교 경주대학 1991 東國論集 Vol.10 No.-
Reye syndrome is a disorder of unknown etiology in which a child recovering form a viral prodrome suddenly develops pernicious vomiting & eventually develops neurologic changes. The syndrome is defined to acute noninflammatory encephalopathy with fatty degeneration of liver and other organs. The coagulopathy or Reye syndrome is associated with proloned PT caused by the mitochondrial injury compromising synthesis of proteins and clotting factors in liver. In this case, we observed ICH on right parietal and occipital area in brain CT. Actually, bleeding in the major organ is extremely rare in Reye syndrome, this may be the first case report of CNS bleeding in Korea associated with Reye syndrome. In addition to case report, we present a brief review of the related literatures.
정유석 ( Yoo Seock Cheong ),고윤석 ( Youn Suck Koh ),권복규 ( Ivo Kwon ),김옥주 ( Ock Joo Kim ),박재현 ( Jae Hyun Park ),손명세 ( Myong Sei Sohn ),이일학 ( Il Hak Lee ),임기영 ( Ki Young Lim ),장기현 ( Kee Hyun Chang ) 한국의료윤리학회 2008 한국의료윤리학회지 Vol.11 No.2
In 2007, the Korean Society for Medical Ethics Education (KSMEE), with the support of the Korean Academy of Medicine (KAM), developed a clinical ethics core curriculum for medical trainees in Korea. This article provides a summary of the contents of the curriculum developed by the KSMEE. The curriculum consists of six main subjects: doctor-patient relationships, interpersonal relationships with colleagues and paramedical persons, ethics related health policy, withholding and withdrawing of treatment, research ethics, and professionalism. Each main subject has three to four sub-sections. All issues were generated by medical ethics experts by means of group discussions and a survey of medical trainees at various university hospitals in Korea. Each subtitle has four parts including a general overview, learning goals, and two to three relevant clinical cases with key references. This curriculum is primarily for medical trainees, who are not well prepared for the diverse ethical challenges and ethical dilemmas they may face during their daily clinical activities.