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- 저자 : Kazuaki IMAI (검색결과 2 건)
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Ayaka Iura,Aiko Kawano,Kazuaki IMAI,Katsuyuki Konnai,Ryo Onose,Hisamori Kato 대한부인종양학회 2018 Journal of Gynecologic Oncology Vol.29 No.5
Objective: Optimal debulking in interval debulking surgery (IDS) after neoadjuvant chemotherapy (NAC) has been reported as a prognostic factor for patients with ovarian cancer. However, the identification of microscopic residual disease (MRD) using visualization and palpation is subjective. Peritoneal washing cytology (PWC) during IDS is an easy-to-implement, objective approach for assessing disease status, although its clinical relevance and association with MRD is not known. The aim of this study was to evaluate the efficacy of PWC during IDS. Methods: In total, 164 patients diagnosed with ovarian cancer at our institution were retrospectively evaluated, including 64 who had received NAC. Seventeen patients had undergone an exploratory laparotomy followed by NAC, while the remaining patients were diagnosed based on imaging, peritoneal cytology, and tumor markers. The PWC was performed before intraperitoneal observation at laparotomy during IDS. Results: NAC-treated patients had stage III–IV disease. IDS was performed in 78.1% of NAC-treated patients. Seventeen patients (26.6%) were PWC-negative and 33 patients (51.6%) were PWC-positive. Fourteen patients (21.9%) had progressive disease and were ineligible for IDS. The median overall survival of the PWC-negative, PWC-positive, and non-IDS groups was 47, 18, and 5 months, respectively. The differences were significant (p<0.01). PWC was an independent prognostic factor in the multivariate Cox regression analysis (p<0.001). Conclusion: PWC during IDS may be a prognostic factor for NAC-treated patients with ovarian cancer. PWC may be more useful than visualization and palpation in IDS for determining the presence of MRD.
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MBE Growth of ZnSe Films on Lattice-Matched InxGa1-xAs Substrates
Takashi KARITA,Kazuhiko Suzuki,Takayuki SAWADA,Kazuaki IMAI,Satoru SETO 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.53 No.1
Raman scatering of ZnSe layers grown on nearly latice matched InxGa1-xAs substrates (x = 0 -0.092) by using molecular beam epitaxy (MBE) have ben investigated. The Raman shift of the ZnSe longitudinal optical (LO) phonon stays nearly constant while the line width Γ increases with increasing indium molar fraction of the substrates. The results are analyzed based on the two-parameter spatial corelation model. The intrinsic line width of ZnSe LO is found to depend strongly on the spatial corelation length of the substrate.
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