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- 저자 : Karami, Armin (검색결과 129 건)
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Buckling analysis of nanoplate-type temperature-dependent heterogeneous materials
Karami, Behrouz,Karami, Sara Techno-Press 2019 Advances in nano research Vol.7 No.1
This paper develops a four-unknown refined plate theory and the Galerkin method to investigate the size-dependent stability behavior of functionally graded material (FGM) under the thermal environment and the FGM having temperature-dependent material properties. In the current study two scale coefficients are considered to examine buckling behavior much accurately. Reuss micromechanical scheme is utilized to estimate the material properties of inhomogeneous nano-size plates. Governing differential equations, classical and non-classical boundary conditions are obtained by utilizing Hamiltonian principles. The results showed the high importance of considering temperature-dependent material properties for buckling analysis. Different influencing parametric on the buckling is studied which may help in design guidelines of such complex structures.
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SARS-CoV-2 in brief: from virus to prevention
Hassan Karami,Zeinab Karimi,Negin Karami 질병관리본부 2022 Osong Public Health and Research Persptectives Vol.13 No.6
The recent outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a highly transmissible virus with a likely animal origin, has posed major and unprecedented challenges to millions of lives across the affected nations of the world. This outbreak first occurred in China, and despite massive regional and global attempts shortly thereafter, it spread to other countries and caused millions of deaths worldwide. This review presents key information about the characteristics of SARS-CoV-2 and its associated disease (namely, coronavirus disease 2019) and briefly discusses the origin of the virus. Herein, we also briefly summarize the strategies used against viral spread and transmission.
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Karami, Esmaeil,Alishahi, Mojtaba,Molayemraftar, Taravat,Ghorbanpour, Masoud,Tabandeh, Mohammad Reza,Mohammadian, Takavar The Korean Society of Fisheries and Aquatic Scienc 2019 Fisheries and Aquatic Sciences Vol.22 No.10
Background: Lactococcus garvieae is one of the most important risk factors in the rainbow trout culture. Therefore, the purpose of this study was to identify and detect strains isolated from rainbow trout suspected of having Lactococcus garvieae using biochemical characteristics and PCR and determination of the degree of severity of isolated strains. Methods: In this study, the cause of lactococcosis in selected rainbow trout farms in Kohkilooieh and Boyerahmad province was assayed. Gram-positive and catalase-negative bacterial isolates were first obtained from selected trout fish farms using conventional biochemical tests and PCR assay. The 10-day LD<sub>50</sub> method (concentration causing 50% mortality in 10 days) was used to determine the severity of the isolated bacteria. Results: One bacterial isolate was detected from all sampled fish which confirmed as Lactococcus garvieae using a specific PCR assay based on the 16S rDNA gene by producing a single band of 1107 bp. Analysis of the rate of mortality showed that the 10-day LD<sub>50</sub> was 4.6 × 10<sup>5</sup> CFU/fish. The results of this study showed that isolated bacteria had high severity for rainbow trout. The presence of bacteria in internal organs of suspected fish showed a severe systemic infection in challenged fish. Antibiogram assay also indicated that the isolated Lactococcus garvieae were resistant to some mostly used antibiotics in rainbow trout. Conclusions: According to current research, it can be concluded that the condition of lactococcosis in the studied area is not suitable, and despite the presence of disease, there is no proper action to control and prevent the disease. Unfortunately, isolated bacteria from the studied area have a very high severity compared to bacteria isolated from other regions of the country or other countries. Therefore, further investigation is needed to determine the cause of this difference and possibly in the design of the vaccine.
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Sensitivity analysis of numerical schemes in natural cooling flows for low power research reactors
Karami, Imaneh,Aghaie, Mahdi Techno-Press 2017 Advances in energy research Vol.5 No.3
The advantages of using natural circulation (NC) as a cooling system, has prompted the worldwide development to investigate this phenomenon more than before. The interesting application of the NC in low power experimental facilities and research reactors, highlights the obligation of study in these laminar flows. The inherent oscillations of NC between hot source and cold sink in low Grashof numbers necessitates stability analysis of cooling flow with experimental or numerical schemes. For this type of analysis, numerical methods could be implemented to desired mass, momentum and energy equations as an efficient instrument for predicting the behavior of the flow field. In this work, using the explicit, implicit and Crank-Nicolson methods, the fluid flow parameters in a natural circulation experimental test loop are obtained and the sensitivity of solving approaches are discussed. In this way, at first, the steady state and transient results from explicit are obtained and compared with experimental data. The implicit and crank-Nicolson scheme is investigated in next steps and in subsequent this research is focused on the numerical aspects of instability prediction for these schemes. In the following, the assessment of the flow behavior with coarse and fine mesh sizes and time-steps has been reported and the numerical schemes convergence are compared. For more detail research, the natural circulation of fluid was modeled by ANSYS-CFX software and results for the experimental loop are shown. Finally, the stability map for rectangular closed loop was obtained with employing the Nyquist criterion.
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FIXED POINT RESULTS ON S-METRIC SPACE VIA SIMULATION FUNCTIONS
Karami Abdullah,Sedghi Shaban,Shobe Nabi,Hyun H.G. 경남대학교 기초과학연구소 2019 Nonlinear Functional Analysis and Applications Vol.24 No.4
In this paper, we prove some common xed point theorems for two mappings satisfying generalized contractive condition in S-metric spaces via simulation functions. Our results extend and improve several previous well-known works.
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Estimating the Economic Burden of Premature Mortality Caused by Cancer in Iran: 2006-2010
Karami-Matin, Behzad,Najafi, Farid,Rezaei, Satar,Khosravi, Ardashir,Soofi, Moslem Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.4
Background: Cancer is currently one of the main public health problems all over the world and its economic burden is substantial both for health systems and for society as a whole. To inform priorities for cancer control, we here estimated years of potential life lost (YPLL) and productivity losses due to cancer-related premature mortality in Iran from 2006 to 2010. Materials and Methods: The number of cancer deaths by sex and age groups for top ten leading cancers in Iran were obtained from the Ministry of Health and Medical Education. To estimate the YPLL and the cost of productivity loss due to cancer-related premature mortality, the life expectancy method and the human capital approach were used, respectively. Results: There were 138,228 cancer-related deaths in Iran (without Tehran province) of which 76 % (106,954) were attributable to the top 10 ranked cancers. Some 63 % of total cancer-related deaths were of males. The top 10 ranked cancers resulted in 106,766,942 YPLL in total, 64,171,529 (60 %) in males and 42,595,412 (40%) in females. The estimated YPPLL due to top 10 ranked cancers was 58,581,737 during the period studied of which 32,214,524 (54%) was accounted for in males. The total cost of lost productivity caused by premature deaths because of top 10 cancers was 1.68 billion dollars (US$) from 2006 to 2010, ranging from 251 million dollars in 2006 to 283 million dollars in 2010. Conclusions: This study showed that the economic burden of premature mortality attributable to cancer is significant for Iranian society. The findings provide useful information about the economic impact of cancer for health system policy/decision makers and should facilitate planning of preventive intervention and effective resource allocation.
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Karami, K.,Buyukgungor, O.,Dalvand, H. Korean Chemical Society 2011 대한화학회지 Vol.55 No.1
전이금속 이온인 수은(II) 및 은(I)에 대한 $\alpha$-케토안정화된 일리드화 인 $Ph_3P$=CHC(O) $C_6H_4$-X (X=Br, Ph)의 착물 반응 행동을 연구하였다. 수은(II) 착물 {$HgX_2$ [Y]} 2 ($Y_1$=4-bromo benzoyl methylene triphenyl phosphorane; X=Cl(1), Br(2), I(3), $Y_2$=4-phenyl benzoyl methylene triphenyl phosphorane; X=Cl(4), Br(5), I(6))는 $Y_1$ 및 $Y_2$를 $HgX_2$ (X=Cl, Br, I)와 각각 반응시켜 제조하였다. $\alpha$-케토안정화된 일리드화 인($Y_2$)의 은(I) 착물 [Ag$(Y_2)_2$] X(X=$BF_4$(7), OTf(8))는 이러한 일리드와 AgX(X=$BF_4$, OTf)를 아세톤에서 반응시켜 얻었다. 착물 (1)과 (4)의 결정구조를 고찰하였다. 일리드의 C-배위 이핵착물과 트랜스-구조의 착물$[Y_1HgCl_2]_2$. $CHCl_3$ (1) 및 $[Y_2HgCl_2]_2$ (4)를 형성하는 이들 반응에 대해 단결정 X-선 분석을 통해 고찰하였다. 모든 착물(1-3)은 IR, $^1H$ 및 $^{31}P$ NMR 뿐만아니라 $^{13}$CNMR을 통하여 확인하였다. The complexation behavior of the $\alpha$-ketostabilized phosphorus ylides $Ph_3P$=CHC(O) $C_6H_4-X$ (X=Br, Ph) towards the transition metal ions mercury (II) and Silver (I) was investigated. The mercury(II) complex {$HgX_2$ [Y]} 2 ($Y_1$=4-bromo benzoyl methylene triphenyl phosphorane; X=Cl(1), Br(2), I(3), $Y_2$=4-phenyl benzoyl methylene triphenyl phosphorane; X=Cl(4), Br(5), I(6)) have been prepared from the reaction of $Y_1$ and $Y_2$ with $HgX_2$ (X=Cl, Br, I) respectively. Silver complexes [$Ag(Y_2)_2]$ X(X=$BF_4$(7), OTf(8)) of the $\alpha$-keto-stabilized phosphorus ylides ($Y_2$) were obtained by reacting this ylide with AgX (X=$BF_4$, OTf) in $Me_2CO$. The crystal structure of complexes (1) and (4) was discussed. These reactions led to binuclear complexes C-coordination of ylide and trans-like structure of complexes $[Y_1HgCl_2]_2$. $CHCl_3$ (1) and $[Y_2HgCl_2]_2$ (4) is demonstrated by single crystal X-ray analyses. Not only all of complexes have been studied by IR, $^1H$ and $^{31}P$ NMR spectroscopy, but also complexes 1-3 have been characterized by $^{13}$CNMR.
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Karami, Hadi,Baradaran, Behzad,Esfehani, Ali,Sakhinia, Masoud,Sakhinia, Ebrahim Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2
Background: Acute myeloid leukemia (AML) is a fatal hematological malignancy which is resistant to a variety of chemotherapy drugs. Myeloid cell leukemia-1 (Mcl-1), a death-inhibiting protein that regulates apoptosis, has been shown to be overexpressed in numerous malignancies. In addition, it has been demonstrated that the expression level of the Mcl-1 gene increases at the time of leukemic relapse following chemotherapy. The aim of this study was to target Mcl-1 by small interference RNA (siRNA) and analyze its effects on survival and chemosensitivity of acute myeloid leukemia cell line HL-60. Materials and Methods: siRNA transfection was performed with a liposome approach. The expression levels of mRNA and protein were measured by real-time quantitative PCR and Western blot analysis, respectively. Trypan blue assays were performed to evaluate tumor cell growth after siRNA transfection. The cytotoxic effects of Mcl-1 siRNA (siMcl-1) and etoposide were determined using MTT assay on their own and in combination. Apoptosis was quantified using a DNA-histone ELISA assay. Results: Transfection with siMcl-1 significantly suppressed the expression of Mcl-1 mRNA and protein in a time-dependent manner, resulting in strong growth inhibition and spontaneous apoptosis. Surprisingly, pretreatment with siMcl-1 synergistically enhanced the cytotoxic effect of etoposide. Furthermore, Mcl-1 down-regulation significantly increased apoptosis sensitivity to etoposide. No significant biological effects were observed with negative control siRNA treatment. Conclusions: Our results suggest that specific suppression of Mcl-1 by siRNA can effectively induce apoptosis and overcome chemoresistance of leukemic cells. Therefore, siMcl-1 may be a potent adjuvant in leukemia chemotherapy.
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