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Upper-Limb Rehabilitation Exercises Using Haptic Device System
Yoshiyuki Takahashi,Takafumi Terade,Kaoru Inoue,Yuko Ito,Hokyoo Lee,Takashi Komeda 한국과학기술원 인간친화 복지 로봇 시스템 연구센터 2003 International Journal of Assistive Robotics and Me Vol.4 No.2
We have applied a haptic device to the rehabilitation tool and made efforts to integrate the motion and sensory therapy, in order to avoid boredom that the patients usually feel. This rehabilitation tool system consists of a haptic device, a display, a computer, and software for training. When the user moves the grip, the haptic device provides a virtual force and it can either assists the movement of the arm or work against it. We have carried out a preliminary experiment with young and middle age group and elderly group. It aims to confirm the functionality of this system and to collect the reference data for the evaluation of the upper-limb disability. The results of our experiment show that the system could be used to evaluate the patient"s ability of upper-limb motion.
Anti-emetic Principles of Alpinia katsumadai Hayata
Ye Yang,Kaoru Kinoshita,Kiyotaka Koyama,Kunio Takahashi,Takaaki Tai,Yoshiki Nunoura,Kazuo Watanabe 한국생약학회 1999 Natural Product Sciences Vol.5 No.1
Bioassay-guided fractionation of anti-emetic constituents of Alpiraia katsumadai Hayata was performed. Nine compounds including one novel compound, (3R,5S)-trans-3,5-dihydroxy-1,7-diphenyl-1-heptene (9) were isolated from it. Among these compounds, four diarylheptanoids, one sesquiterpenoid and one flavonoid showed anti-emetic activity on copper sulfate induced-emesis in young chicks.
Masashi Uehara,Jun Takahashi,Shugo Kuraishi,Masayuki Shimizu,Shota Ikegami,Toshimasa Futatsugi,Kaoru Aoki,Keijiro Mukaiyama,Nobuhide Ogihara,Hiroyuki Hashidate,Hiroki Hirabayashi,Hiroyuki Kato 대한척추외과학회 2015 Asian Spine Journal Vol.9 No.4
Study Design: Retrospective chart review. Purpose: A comparison of mini open foraminotomy (MOF) for cervical radiculopathy using either large tubular (LT) or TrimLine (TL) retractors. Overview of Literature: Posterior foraminotomy relieves compression of the cervical nerve root in radiculopathy patients. However, invasion of the paravertebral muscle may cause major problems in these patients. To address these problems, we performed MOF. Methods: Twenty cervical radiculopathy patients (16 male and 4 female) who underwent MOF between May 2004 and August 2011 were assigned to LT and TL groups. Each group contained 10 subjects. Surgical and clinical outcomes were compared. Results: The average operating time in the TL group was significantly shorter than that in the LT group. The final follow-up mean neck disability indices significantly improved compared to the preoperative values (LT group, 12.0±7.8 vs. 28.0±9.4; TL group, 6.0±5.9 vs. 21.9±10). The final follow-up neck pain visual analog scale (VAS) scores also decreased significantly from the preoperative of 8.0±1.5 and 2.5±2.5 to the final follow-up values of 2.2±2.2 and 1.0±2.5 in the LT and TL groups, respectively. The recovery rate for the neck pain VAS score was 70.0±31.9 in the LT group and 87.0±32.0 in the TL group, thus suggesting no significant difference between the two groups. Conclusions: MOF with the TL retractor is an easy and safe procedure. Furthermore, the use of the TL retractor allows for a minimally invasive and effective surgical treatment of cervical radiculopathy patients.
Fungemia due to Trichosporon dermatis in a patient with refractory Burkitt’s leukemia
Satoshi Hashino,Shojiro Takahashi,Rena Morita,Hiroe Kanamori,Masahiro Onozawa,Takahito Kawamura,Kaoru Kahata,Takeshi Kondo,Issei Tokimatsu,Takashi Sugita,Koji Akizawa,Masahiro Asaka 대한혈액학회 2013 Blood Research Vol.48 No.2
Fungemia due to Trichosporon dermatis in a patient with refractory Burkitt’s leukemia
Satoshi Hashino,Shojiro Takahashi,Rena Morita,Hiroe Kanamori,Masahiro Onozawa,Takahito Kawamura,Kaoru Kahata,Takeshi Kondo,Issei Tokimatsu,Takashi Sugita,Koji Akizawa,Masahiro Asaka 대한혈액학회 2013 Blood Research Vol.48 No.2
Iseki, Mineo,Matsunaga, Shigeru,Murakami, Akio,Ohno, Kaoru,Shiga, Kiyoshi,Yoshida, Kazuichi,Sugai, Michizo,Takahashi, Tetsuo,Hori, Terumitsu,Watanabe, Masakatsu Korean Society of Photoscience 2002 Journal of Photosciences Vol.9 No.2
Euglena gracilis abruptly changes its swimming direction after a sudden increase or decrease in incident light intensity, that is, step-up or step-down photophobic responses, resulting in photoavoidance or photoaccumulation, respectively. To identify the photoreceptor molecules for these UV-A/blue-light type photobehaviors, we purified a flavoprotein from isolated putative photosencory organelles (PFBs) of Euglena. The purified flavoprotein, which noncovalently bound flavin adenine dinucleotide (FAD), seemed to be a heterotetramer of alpha- and beta-subunits. Predicted amino acid sequences of each of the subunits were similar to each other and contained two FAD-binding domains each followed by an adenylyl cyclase catalytic domain. The purified flavoprotein actually showed adenylyl cyclase activity, being drastically elevated by blue-light irradiation. Suppression of gene expression of the flavoprotein (Photoactivated Adenylyl Cyclase, PAC) by RNA interference (RNAi) caused loss of the step-up photophobic response, demonstrating that PAC actually mediates photoavoidance of Euglena.