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Anti-emetic Principles of Alpinia katsumadai Hayata
Ye Yang,Kaoru Kinoshita,Kiyotaka Koyama,Kunio Takahashi,Takaaki Tai,Yoshiki Nunoura,Kazuo Watanabe 한국생약학회 1999 Natural Product Sciences Vol.5 No.1
Bioassay-guided fractionation of anti-emetic constituents of Alpiraia katsumadai Hayata was performed. Nine compounds including one novel compound, (3R,5S)-trans-3,5-dihydroxy-1,7-diphenyl-1-heptene (9) were isolated from it. Among these compounds, four diarylheptanoids, one sesquiterpenoid and one flavonoid showed anti-emetic activity on copper sulfate induced-emesis in young chicks.