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Teudom Kann,서승일,연재훈 한국철도학회 2023 한국철도학회논문집 Vol.26 No.2
Curve squeal noise is an intense tonal noise that occurs when a train goes through a narrow curve and is generated by the wheel contacting the rail. The squealing noise is an issue in mountain tram development projects. In this study, 1:7.5 scaled equipment is proposed to produce the squealing noise based on rolling speed, rolling direction, angle of attack, and preload ratio. Solid-stick lubricant is used as a mitigation method. The similarity law is applied and a finite element analysis code is used to compare the natural frequency of full-scale and small-scale results. The results show that the scaled equipment can generate squealing noise and that rolling backward direction has a higher possibility of generating squealing noise. Moreover, the frequency similarity approach is verified, and the solid stick lubricant is found to successfully mitigate the squealing noise even at high rolling speed and angle of attack.
Rondla Rohini,P. Muralidhar Reddy,Kanne Shanker,Kodipelli Kanthaiah,Vadde Ravinder,Anren Hu 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.7
A series of mono and bis 2-2-(arylidineaminophenyl)indole azomethines have been synthesized by a condensation reaction of 2-(2-amino phenyl) indole with various mono and diketones RCO-R^l /R-CO-X-CO-R^l (1:1/2:1 ratio) in ethanol media. The synthesized azomethines were characterized via IR, ^1H-NMR, ^13C-NMR, MS and elemental analysis. The antimicrobial activity of these compounds against different bacteria and fungi was also evaluated.
Urban Harvest + Approach for 0-impact Built Environments, Case Kerkrade West
Rovers, Ronald,Rovers, Vera,Leduc, Wouter,Gommans, Leo,Sap, Herwin,Van Kann, Ferry Sustainable Building Research Center 2011 International journal of sustainable building tech Vol.2 No.2
The need to restructure our society into a sustainable society has been recognised by many, though a clear direction and ambition in this process usually fails. At the Research Institute for the Built Environment of Tomorrow, RiBuilT, the definition of a sustainable society has been summarised as the 'Concept of O': O for a circular approach of resource management, and 0 (zero) for 0-impacts of our activities; 0-energy, 0-materials, 0-water, 0-landuse and 0-air (pollution). In order to apply this approach to existing urban environments, the Urban Harvestplus approach was developed. This paper will analyse the first test results of the actual implementation of this approach on the Dutch district of Kerkrade West. The pilot on Kerkrade West shows that even when the production of resources is maximised and the demand for them will be drastically reduced, it will still be hard to achieve the 0-impact state. We need new and more innovative solutions to actually make it happen. However, the Urban Harvestplus approach proved to be a straight forward approach in getting closer to the zero-impact situation. It also clarified the interaction between resources and made clear that resource cycles should never be considered on their own, but always in relation to each other to avoid sub-optimisation. Many questions and areas are left for further research, but we believe Urban Harvest-plus represents a strong basis to depart from.
Serum Uric Acid: A Risk Factor and a Target for Treatment?
Feig, Daniel I.,Mazzali, Marilda,Kang, Duk-Hee,Nakagawa, Takahiko,Price, Karen,Kannelis, John,Johnson, Richard J. American Society of Nephrology 2006 Journal of the American Society of Nephrology Vol.17 No.4
<P>Serum uric acid was first noted to be associated with increased BP by Frederick Mohamed in the 1870s. Although the link was rediscovered periodically over the years, it generally was dismissed as a surrogate marker for decreased renal function that led to increased uric acid and increased risk for hypertension and cardiovascular (CV) disease. Recently, however, several lines of evidence suggest that increased serum uric acid may be a significant modifiable risk factor. Increased serum uric acid is associated with increased risk for future hypertension in several large longitudinal clinical trials as well as an independent risk factor for poor CV prognosis. Animal model experiments demonstrate that increased serum uric acid causes increased BP that initially is reversible but becomes irreversible, salt sensitive, and uric acid independent over time. The mechanisms include the direct action of uric acid on smooth muscle and vascular endothelial cells. Finally, in adolescents with new-onset essential hypertension, the prevalence of elevated serum uric acid is >90%, and preliminary clinical trial evidence suggests that agents that lower serum uric acid may lower BP in this select population. Although the investigations are still preliminary, serum uric acid represents a possible new and intriguing target for the reduction of morbidity and mortality associated with hypertension and CV disease.</P>
Jang, Hong-Gi,Heo, Buk-Gu,Park, Yong Seo,Namiesnik, Jacek,Barasch, Dinorah,Katrich, Elena,Vearasilp, Kann,Trakhtenberg, Simon,Gorinstein, Shela Humana Press 2012 Applied biochemistry and biotechnology Vol.167 No.7
<P>Seeds and leaves of indigo (Polygonum tinctorium Ait.) plant were investigated and compared with another medicinal plant named prolipid for their properties such as chemical composition, antioxidant, and anticancer effects by Fourier transform infrared, three-dimensional fluorescence spectroscopy, and electrospray ionization-MS in negative mode. It was found that polyphenols, flavonoids, and flavanols were significantly higher in prolipid (P<0.05), following by indigo mature leaves, immature leaves, and seeds. Methanol extract of mature indigo leaves in comparison with the ethyl acetate extract showed higher inhibition of proliferation. The interaction between polyphenol extracts of indigo mature leaves and BSA showed that indigo has a strong ability, as other widely used medicinal plants, to quench the intrinsic fluorescence of BSA by forming complexes. In conclusion, indigo mature leaves were compared with prolipid. High content of bioactive compounds, antioxidant, fluorescence, and antiproliferative properties of indigo justifies the use of this plant as a medicinal plant and a new source of antioxidants.</P>