8년간(1992~1999) 산업안전보건연구원에 의뢰된 직업병 심의 사례 분석

강성규,김규상,김양호,최정근,안연순,진영우,최병순,양정선,김은아,채창호,최용휴,김대성,박정선,정호근 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

Objectives : Pneumoconisis and noise-induced hearing loss (NIHL) have been reported as main occupational diseases by the Special Health Examination. The Industrial Accident Compensation Insurance has reported various work-related diseases, however, these two diseases occupied almost a half of compensated cases. Therefore, it was not well known about the status of occupational diseases other than pneumoconiosis, NIHL, and cardio-cerebrovascular accident (CVA). This study was conducted to analyze claimed cases as an occupational disease, that was requested to the Korea Industrial Safety and Health Agency (KOSHA). Methods : The local office of the Korea Labor Welfare Corporation (KLWC) has asked the KOSHA for confirmation of claimed cases as an occupational disease. We analyzed 379 cases requested from KLWC, the Ministry of Labor, employers, unions and occupational health agencies from 1992 to 1999. Results : Male was 80.7 % of the requested cases. Their mean age was 42 years old and 75.5 % of them were more than 35 years old. The requested cases were increased rapidly from 25 cases in 1992 to 108 cases in 1999 and the accept rate was 50.7 %. The majority of requested cases were respiratory diseases(22.4%), cancers(18.5%), Neuropsychiatric problems(14.5%), and musculoskeletal problems(13.5%). The accept rate was high in reproductive, respiratory, musculoskeletal and digestive disorders and low in neuropsychiatric, renal and otologic problems and occupational cancers. 73.6% of them were caused by chemical agents, especially 28.5 % were by organic solvents. 67% of them were clinically confirmed at university hospitals. A half of the cases were from KyongIn area, even the request came from the whole country. Conclusions : A claim was common in workers whose age was over 35 years old and exposure history was over 10 years. The respiratory diseases and neuropsychiatric disorders were still main problems in occupational health and occupational cancers was increasing even though its accept rate was not high yet.

乳牛眞菌中毒症의 原因이 되었던 變質옥수수겨에서 分離된 Aspergillus flavus에 對하여

康炳奎,金五南 全南大學校 農漁村開發硏究所 1983 農業科學技術硏究 Vol.18 No.1

1979年 6月에 全北地方의 한 酪農牧場에 發生하였던 乳牛急性中毒症에 대하여 그 病因學的原因을 究明코자 給與變質옥수수겨에 대한 病原菌分離를 실시하였다. 옥수수겨의 變質은 Aspergillus flavus의 오염임이 밝혀졌고, 同菌의 粗毒素는 2週齡오리에 致死的毒性을 나타내고 있음이 증명되었다. Etiological studies were carried out to the case of acute moldy corn barn poisoning of cows occured in 1979 at a dairy farm of Chunbug district. Some strain of Aspergiilus sp. was isolated from the caused feed stuff of moldy corn barn and it was identified as Aspergillus flavus(strain Kochang-1) by cultural and morphological examination and also demonstrated that it has a lethal toxicity in geese and it was a toxin-producing strain.

導入肉牛에 集團發生한 皮膚絲狀菌病(輪癬)에 對하여

康炳奎,魏聖河,朴承柱 全南大學校 農漁村開發硏究所 1984 農業科學技術硏究 Vol.19 No.-

1982年 7月 全南順天地域의 肥育用肉牛에 地域 集團的으로 發生한 皮膚疾患에 대한 炳因學的 調査를 하였던 바, Trichophyton verrucosum에 의한 皮膚絲狀菌炳(輪癬)임을 확인하였다. Bovine ringworm caused by Trichophophyton verrucosum was diagnosed clinically and mycologically. An enzootic of this infection was found in the area of Sunchum district of Korea from Spring to August, 1982.

肥肉豚의 血液化學値에 關한 硏究

李政吉,康炳奎,魏聖河,朴承柱,朴來生 全南大學校 農漁村開發硏究所 1981 農業科學技術硏究 Vol.16 No.1

全羅南道 順天地方을 中心으로 한 養豚場에서 出荷된 肥肉豚을 對象으로 血液化學値를 調査했다. 돼지의 年齡은 7個月부터 13個月이었으며, 總 276頭(♀ 181,♂ 95)를 對象으로 屠畜場에서 採血했는데 Landrace와 Berkshire의 一代難種이 大部分이었다. 한편 本 實驗에서 使用한 무??豚은 모두가 去勢한 것이었다. 1. 測定한 血液化學値는 血淸?萄糖量, 血淸總蛋白量, ablumin量, globulin量, 血淸尿素?素量, 血淸 cholesterol量, calcium量, 無機燐量, 血淸 transaminase(SGOT와 SGPT)等이었다. 2. 本 調査에서 나타난 각종 血液化學値의 範圍 및 平均値는 이미 報告된 結果와 거의 一致하였다. 3. 血淸cholesterol量은 性別差가 없었고 겨울에 높은値를 보인 反面, 여름과 가을에는 낮은 치를 보였다. 4. 血淸總蛋白量의 季節的變動은 globulin量의 變動에 起因한 것이었고, globulin量은 全般的으로 높게 나타났는데 特히 여름철의 增加가 뚜렷했다. Samples of blood were taken from 276 fattening pigs(181 intact females and 95 castrated males) at slaughter and serum chemical values were determined. The pigs were from Suncheone area, Chonnam Province; their age ranged 7 to 13 months; most of them were crossbreds of Landrace and Berkshire. 1. Determined blood chemical values in the prestent study were glucose, total protein, albumin, globulin, serum urea nitrogen, cholesterol, calcuim, phosphorus, serum glutamin oxalacetic transaminase and serum glutamic pyruvic transaminase. 2. The ranges and means of the chemical values in the present study were reconcilable with the normal values previously reported. 3. Sex differences between castrated males and intact prepubertal females were not observed in serum cholesteol levels. There were significant differences between the means of seasons, with the higher cholesterol values being observed during the winter as compared with summer and fall. 4. Seasonal changes of total protein cantent were due to the seasonal changes of globulin values. The globulin values in the present study were higher than those reported previously by others; the values were highest during summer season.

全南地方 飼育乳牛에 있어서 繁殖障害의 實態 및 發生要因分析

朴永埈,康炳奎 全南大學校 農漁村開發硏究所 1972 農業科學技術硏究 Vol.6 No.-

A systemic studies for reproductive and nutritional problems to conduct a herd infertility examinations were performed on one hundred and fourty seven cows in Kwang-ju, Chonnam area during the period from June 1 to August 30, 1971. The examination involves evaluation of breeding history and laboratory tests to make an objective diagnosis on nutrio-reproductive syndrome. An analysis of data from a dairy herd with a repeat breeding problems is presented and the purpose of this paper is to discuss some management practices that relate to cattle fertility, some of which are directly applicable today and some that may become available in the future. 1. Total of 147 cows examined were grouped as pregnant(60.5%), anestrus after breeding(10.8%), unknown to conception(15.7%), repeat breeder(10.8%) and others(2.1 %). Evaluation for the breeding history of the herd and the reasons for culling indicated that the repeat breeder was the major problems especially on the large herd (type-A and B farm) than the small one (type-C) in this area. 2. The reproductive histories and results of reproductive examainations were as follows. Calving intervals were 512 days(17.4 months), the interval from parturition to first breeding 91.3 days and postpartum interval to first estrus 52.6 days respectively. Service per conception rate was observed as 1.4, and the 30-60-day and 60-90-day nonereturns were 42.9 and 91.5 per cent. These findings were a sign that cows might not be cycling by 60 days, or that estrus detection was inferior. 3. Tendency towards a frequency of conception and parturition through one year was evaluated, and it was suggested that the problems of summer sterility should be re-evaluated because of the conception rate was low in August to October. On the other hand, natural breeding was frequently used instead of artificial insemination service on the mating system in this area. 4. The mean value of the examined cows for red blood cell count and hemoglobin values were 5.5×10 6 per cmm and 7.8 grams per 100ml of blood. It was markedly noticed that the mean value of red blood cell of the anestrus after breeding group was lower than that of the pregnant group(P<0.05). It seemed to be a anemic condition because of the mean value was relatively low compared with the reported values in other countries. 5. The mean value for total serum protein was 7.3 grams per 100ml of blood and it was observed that unknown to conception group showed the lowest value, and almost all the cows which showed abnormal values belonged to the repeat breeder group. 6. The mean value for serum calcium was 4.5 mEq per liter of blood, which was coincide with the lowest range of the normal value(4.5 to 5.5mEq/L). Significant differences on the calcium contents were observed between the anestrus after breeding(P<0.05) and repeat breeder group(P<0.01) to pregnant group. On the other hand, the mean value for serum inorganic phosphorus was 7.3mg per 100ml of blood, which was the normal value(7.0 to 7.5mg/100ml). The Ca/P ratio was observed as 1.47 as a mean of total examined cows but more than 50 per cent of repeat breeder and unknown to conception groups showed, hypocalcemia. 7. Normal A/G ratio was observed as a mean, but 62 cows(45.6%) were positive by the liver function test(Hayem's and gross reaction), and almost all the positive cows on the test had the abnormal total serum protein values. 8. No significant features were observed among the groups in the mode of internalparasite infection, but the liver-fluke infection was demonstrated in 48 cows(32.6%), and of these 66.7 per cent were positive in the liver function test. 9. Follow-up evaluations on the results of the laboratory tests strongly suggest that the problems of repeat breeder had a tendency to occur more frequently in the large herd (A and B-type farm), and on the other hand, abnormal conditions, especially on the calcium and phosphorus metabolism, observed more frequently in the subsidiary dairy farm management(C-type). 10. With evaluations for maintaining high fertility in healthy herds and illustrated results from a herd on a systemic herd health programs, followings may be pointed out for recommendation. First, it is necessary to consider a countermeasure against the faulty management followed by the tendency of large herd. Second, the feeding and management technic of farmers should be improved not to-produce the nutrio-reproductive syndrome. Third, the poor test results of repeat breeder and unknown to conception groups may be related with. the reproductive disturbances and actions should be taken to increase the reproductive efficiency.

쥐의 實驗的 葡萄狀球菌性乳房炎에 關한 硏究

李政吉,康炳奎,李採瑢 全南大學校 農漁村開發硏究所 1980 農業科學技術硏究 Vol.15 No.-

The purpose of the present experiment is to determine the suitability of rat model for the experimental staphylococcal mastitis. A strain of Staphylococcus aureus isolated from a case of bovine mastitis was inoculated through the teat canal into the mammary gland of lactating rats. The rats were removed from their offspring or left with them to allow suckling, as required by the experimental design. 1. No generalized reactions or symptoms of mastitis were observed in all rats. 2. At necropsy, affected glands showed discoloration; abscesses up to 2.5mm in diameter were observed in one group of "lactating" rats inoculated with 10x10?? colony-forming units of staphylococcus. 3. Histologically fat droplets retained within the alveoli were prominent in many sections. Epithelial hyperplasia and slight interalveolar fibrosis were also noted. 4. The number of bacteria recovered from the inoculated mammary gland was smaller than that of bacteria inoculated. The bacteria were more readily recoverable from the mammary glands of "non-lactating" rats than from "lactating" rats. 5. To determine a suitable rat model for the experimental staphylococcal mastitis, further studies should be carried out, using different strains of Staphylococcus aureus and also different strains of rats.

Studies on the Diagnosis of Brucellosis in Herd Cows of Chonnam Prefacture: Mainly Coombs Test

Kang, Byong-Kyu 전남대학교 농어촌개발연구소 1965 농어촌개발연구 Vol.3 No.1

Impact of Hospital Volume of Percutaneous Coronary Intervention (PCI) on In-Hospital Outcomes in Patients with Acute Myocardial Infarction: Based on the 2014 Cohort of the Korean Percutaneous Coronary Intervention (K-PCI) Registry

Byong-Kyu Kim,Deuk-Young Nah,Kang Un Choi,Jun-Ho Bae,Moo-Yong Rhee,Jae-Sik Jang,Keon-Woong Moon,Jun-Hee Lee,Hee-Yeol Kim,Seung-Ho Kang,Woo hyuk Song,Seung-Uk Lee,Byung-Ju Shim,Hangjae Chung,Min Su Hyo 대한심장학회 2020 Korean Circulation Journal Vol.50 No.11

Background and Objectives: The relationship between the hospital percutaneous coronary intervention (PCI) volumes and the in-hospital clinical outcomes of patients with acute myocardial infarction (AMI) remains the subject of debate. This study aimed to determine whether the in-hospital clinical outcomes of patients with AMI in Korea are significantly associated with hospital PCI volumes. Methods: We selected and analyzed 17,121 cases of AMI, that is, 8,839 cases of non-ST-segment elevation myocardial infarction and 8,282 cases of ST-segment elevation myocardial infarction, enrolled in the 2014 Korean percutaneous coronary intervention (K-PCI) registry. Patients were divided into 2 groups according to hospital annual PCI volume, that is, to a high-volume group (≥400/year) or a low-volume group (<400/year). Major adverse cardiovascular and cerebrovascular events (MACCEs) were defined as composites of death, cardiac death, non-fatal myocardial infarction (MI), stent thrombosis, stroke, and need for urgent PCI during index admission after PCI. Results: Rates of MACCE and non-fatal MI were higher in the low-volume group than in the high-volume group (MACCE: 10.9% vs. 8.6%, p=0.001; non-fatal MI: 4.8% vs. 2.6%, p=0.001, respectively). Multivariate regression analysis showed PCI volume did not independently predict MACCE. Conclusions: Hospital PCI volume was not found to be an independent predictor of in-hospital clinical outcomes in patients with AMI included in the 2014 K-PCI registry.

Studies on the Diagnosis of Brucellosis in Herd Cows of Chonnam Prefacture: Mainly Coombs Test

Kang, Byong-Kyu 전남대학교 한국농어촌개발연구소 1965 농산어촌개발연구 Vol.3 No.-

동서 집단 안전보장체제에 관한 연구 -경계(警戒)는 자유의 대가이다-

강병규 ( Byong Kyu Kang ) 국방대학교 안보문제연구소 1958 국방연구 Vol.1 No.-