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Acellular Scaffolds as Innovative Biomaterial Platforms for the Management of Diabetic Wounds
Tallapaneni Vyshnavi,Kalaivani C.,Pamu Divya,Mude Lavanya,Singh Sachin Kumar,Karri Veera Venkata Satyanarayana Reddy 한국조직공학과 재생의학회 2021 조직공학과 재생의학 Vol.18 No.5
Diabetic wound (DW) is one of the leading complications of patients having a long history of uncontrolled diabetes. Moreover, it also imposes an economic burden on people suffering from wounds to manage the treatment. The major impending factors in the treatment of DW are infection, prolonged inflammation and decreased oxygen levels. Since these non-healing wounds are associated with an extended recovery period, the existing therapies provide treatment for a limited period only. The areas covered in this review are general sequential events of wound healing along with DW's pathophysiology, the origin of DW and success, as well as limitations of existing therapies. This systematic review's significant aspect is to highlight the fabrication, characterization and applications of various acellular scaffolds used to heal DW. In addition to that, cellular scaffolds are also described to a limited extent.
Senthil-Nathan, S.,Choi, M.-Y.,Paik, C.-H.,Seo, H.-Y.,Kalaivani, K. Academic Press 2009 Ecotoxicology and environmental safety Vol.72 No.6
The effects of two different neem products (Parker Oil(TM) and Neema<SUP>(</SUP>R)) on mortality, food consumption and survival of the brown planthopper, Nilaparvata lugens Stal (BPH) (Homoptera: Delphacidae) were investigated. The LC<SUB>50</SUB> (3.45ml/L for nymph and 4.42ml/L for adult in Parker Oil(TM) treatment; 4.18ml/L for nymph and 5.63ml/L for adult in Neema<SUP>(</SUP>R) treatment) and LC<SUB>90</SUB> (8.72ml/L for nymph and 11.1ml/L for adult in Parker Oil(TM) treatment; 9.84ml/L for nymph and 13.07ml/L for adult in Neema<SUP>(</SUP>R) treatment) were identified by probit analysis. The LC<SUB>90</SUB> (equal to recommended dose) was applied in the rice field. The effective concentration of both Parker Oil(TM) and Neema<SUP>(</SUP>R) took more than 48h to kill 80% of the N. lugens. Fourth instar nymph and adult female N. lugens were caged on rice plants and exposed to a series (both LC<SUB>50</SUB> and LC<SUB>90</SUB>) of neem concentrations. Nymph and adult female N. lugens that were chronically exposed to neem pesticides showed immediate mortality after application in laboratory experiment. The quantity of food ingested and assimilated by N. lugens on neem-treated rice plants was significantly less than on control rice plants. The results clearly indicate the neem-based pesticide (Parker Oil(TM) and Neema<SUP>(</SUP>R)), containing low lethal concentration, can be used effectively to inhibit the growth and survival of N. lugens.
Application of Nanoparticles in Food Preservation and Food Processing
Prakash J.,Vignesh K.,Anusuya T.,Kalaivani T.,Ramachandran C.,Sudha Rani R.,RUBAB MOMNA,KHAN IMRAN,Fazle Elahi,DeogHwanOh,DevanandVenkatasubbu G. 한국식품위생안전성학회 2019 한국식품위생안전성학회지 Vol.34 No.4
This study focuses on the role of nanotechnology in the field of food industries. Bioactive components with antimicrobial activity against food pathogens are encapsulated into nanoparticles (NPs) to improve and extend their efficiency in food preservation. However, these NPs should be biocompatible and nontoxic for humans.Advancement in this field has resulted in the development of NPs for food packaging in some industries. The most commonly used group of NPs in the food industry is metal oxide. As metal oxide NPs such as zinc oxide and titanium dioxide exhibit antimicrobial activity in food materials, the NPs can be used for food preservation with enhanced functional properties. The application and effects of nanotechnology in correlation with the nutritional and sensory properties of foods were briefly discussed with a few insights into safety regulations on nano-based food formulation and preservation.