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      • KCI등재

        한국어 판 WHO-CIDI(Composite International Diagnostic Interview)-Alcohol의 개발:신뢰도 및 타당도 검사

        남궁기,유계준,조은영,송선미,이희상,길계선,조현상,우용일 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.6

        CIDI-Alcohol의 한국어 판 개발을 위해 이를 우리말로 번역, 수정하고, 정신병원에 입원한 환자 90명과 일반인 50명에게 시행한 후 임상 진단과 비교하여 일치도를 봄으로써 그 신뢰도 및 타당도를 조사하였다. 결과는 다음과 같다. 1) 주정 사용 각 진단 범주에 대한 한국어 판 CIDI-Alcohol의 일반 면담자간 진단 일치도는 97%∼100%의 높은 일치도를 보였다. 2) 임상 진단을 기준으로 한 한국어 판CIDI-Alcohol의 주정 사용 장애의 진단 일치도는 각 진단 범주별로 kappa치가 0.43∼0.55로 기존의 연구에 비해 비교적 낮았다. 3) CIDI-Alcohol의 진단 기준을 변화시켜, 각 진단 범주에 대한 임상 진단과의 일치도를 알아본 결과 ICD-10/harmful use는 진단 기준 항목의 수를 2개 이상으로 하였을 때, DSM-Ⅲ-R/주정 의존은 진단 기준 항목의 수를 4개 이상으로 하였을 때 임상 진단과 가장 일치하였다. 이런 결과는 한국어 판 CIDI-Alcohol의 진단 기준이 대체적으로 민감도는 높으나, 특이도가 떨어지는 것으로 생각할 수 있으며, 따라서 본 연구자들에 의해 작성된 한국어 판 CIDI-Alcohol는 일반인구 집단을 대상으로 하는 역학 조사보다는 주정 사용 장애로 이루어진 순수한 실험군의 연구에 적합하다고 생각된다. he authors translated a CIDI-Alcohol, a highly structured diagnostic interview, into Korean and examined the validity and reliability of the Korean version of CIDI-Alcohol. In order to examine the validity and reliability of CIDI-Alcohol, the authors calculated the degree of agreement of CIDI-Alcohol diagnoses between the two lay interviewers and sensitivity, specificity, kappa coefficient between clinical and lay CIDI-Alcohol diagnoses. The results were as follows: 1) Agreement rates of CIDI-Alcohol diagnoses between the two lay interviewers ranged from 97% to 100%. The kappa coefficient for each diagnosis was quite high(0.96-1.0). 2) The kappa value of agreement between clinical and lay CIDI-Alcohol diagnoses ranged from 0.43 to 0.55, which was lower than those of other studies. 3) With canging the diagnostic criteria of CIDI-Alcohol, The highest agreement rate between clinical and CIDI-Alcohol diagnoses was acquired when the authors used two or more diagnostic criteria of ICD-10/harmful use and four or more diagnostic criteria of DSM-Ⅲ-R/ alcohol dependence.

      • 經營의 環境適應에 관한 小考

        康季三 서원대학교 사회과학연구소 1990 사회과학연구 Vol.3 No.-

        Tremendous changes have often been found It Today's business environment. It is one of the most importent problems for a person as well as a business enterprise to survive in the environment with quantum changes. On the bases of this understaning, the purpose of this paper is for the business entrepreneur to search for the better adjustment method on the uncertain environmental changes. After reviewing the contingency theorys for this purpose, I try to approach to the solution of the adjustment problem In these theoretical frameworks. In the process of investigation, the balance theory on organization by Barnard sheds light on this topic. This paper concist of as follows Ⅰ. Introduction Ⅱ. Survey of contingency theories Ⅲ. Discussion Ⅳ. Conclusion

      • 애기물달팽이 및 물달팽이에 對한 肝蛭 및 巨大肝蛭 感染實驗

        田桂植,閔弘基 梨花女子大學校 醫科大學 醫科學硏究所 1990 EMJ (Ewha medical journal) Vol.13 No.2

        The present study was carried out to obtain more information clarification of the susceptibility of the snails, Lymnaea pervia and L. auricularia to the common liver flukes, Fasciola hepatica and F. gigantica. The snails were collected from paddy field and irrigation route in a rural area located along the Han-gang riverside. Cercariae naturally shed from the snails were examined for identification for Fasciola spp. On the other hand, L. pervia and L. auricularia were artificially bred and the offsprings were divided into 3 groups according to day of age; baby snail group(5-7 days of age), young group(15-17) and adult group(more than 60), respectively, and used for infection of miracidia of F. hepatica and F. gigantica. The liver flukes were collected from Korea cattle and morphologically classified for the experiment. Eggs of F. hepatica and F. gigantica were cultured in the laboratory. After hatching, miracidia were used to infect the snails. The results obtained in the present study were summarised as follows ; 1) Cercariae were naturally shed from both species of snails and cercariae of Fasciola spp. were found from 3(1.2%) among 250 individuals of L. pervia, but not from 200 individuals of L. auricularia. 2) Among 376 worms of Fasciola spp., 23(6.1%) were F. hepatica, 144(38.3%) were F. gigantica and 209(55.6%) were intermediate form, respectively. 3) Infection rates in the baby, young and adult snail group of L. pervia treated with F. hepatica miracidia were revealed as 57.6%, 53.1% and 47.9%, respectively, and with F. gigantica were 100.0%, 95.6% and 86.4%, respectively. The differences of infection rates between the corresponding groups of the former and the latter were highly significant(p<0.005). However. infection rates in the baby and young groups of F. hepatica- or F. gigantica-treated L. auricularia were very low, and no infection was established in the adult groups. From the results. it is evidenced that L. pervia is the most suitable intermediate host for F. gigantica and F. hepatica in Korea.

      • 論理的 原子論의 學問方法論에 關하여

        陳快鉉 釜山敎育大學 1978 부산교육대학 논문집 Vol.14 No.1

        Was logische-Philosophische Abhandlung sei und was sie Syntaktische Regel sei, ist umstritten. Man erwartet von ihr ausserordentliche Aufschlu¨ssc. Folglich gelten als begriffen Inhalt in diesem Studium. Erstens: Wa¨hrend die Wissenschaften aufihren Gebieten zwingend gewisse und allgemein Erkenntnisse gewonnen haben, hat die Syntaktische Regel als ihre Untersuchungen u¨ber die sprachlich Wahrheitsfunktion. Zweitens: zwei Forscher, der damals B. Russell und L. Wittgenstion, wurden damit fu¨r ihre Untersuchungen an den Wahrhcitsfunktion geehrt, aus denen hervorging, dass die Lehre von der Verifizierbarkeit in ciner bestimmten Wahrheit sind. Drittens: Logiken vorhanden sind, ihr Grundsa'tze des Syntaktische Regel herausgefordert worden ist. Und also sic muss dazu fu¨hren dic Syntaktische Regel vorgefu¨hrt werden.

      • 인슐린 유사성장인자-I 및 인슐린 유사성장인자-I 수용체가 에토포사이드 유도 아포토시스 억제에 미치는 영향

        남계현,조태호,이지은 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

        The interaction of insulin-like growth factors(IGF) with the IGF-I receptor promotes cell proliferation and survival. The activation of the IGF-I receptor by its ligands IGF-I, IGF-II, and insulin plays critical role in growth and development. The specific role of the IGF-I receptor in development has been recently revealed that targeted disruption of the IGF-I receptor gene resulted in profound fetal growth retardation. Most cell types require IGF-I for growth in culture. In addition to its role in cell cycle progression. IGH-I promotes cell survival has not been clarified. IGF-I may directly prevent apoptosis. However, IGF-I could also promote cell culture survival by survival inducing the prokiferation of viable cells within a damaged cell population. When exposed to the etoposide, R+ cells that constitutively overexpressed the IGF-IR arrested in S phase and subsequently underwent apoptosis as determined by the appearance of the pre-G1 apoptotic peak when studied by the flowcytometry and the charateristic internucleosomal fragmentation of DNA. The addition of IGF-I markly inhibited etoposide-induced apoptosis in a concentration-dependant manner. IGF-I was less effective in preventing apoptosis in parental R-and TC4 cells. These results demonstrate an important role for the IGF-I receptor as an inhibitor of apoptosis, independent of its mitogenic actions. These findings establish the relationship between IGF-IR levels and the extents of apoptosis. The TC4 cells expressing the truncated IGF-I receptor with a 108-amino-acid C-terminal truncation exhibited a dramatically impared ability to prevent the apoptosis, indication that truncated IGF-I receptor lose the ability to prevent the apoptosis at the intramolecular level.

      • 全北大學校 樹木園의 造成 및 發展方向에 관한 硏究

        金癸煥,朴鍾旻 全北大學校 1996 論文集 Vol.41 No.-

        The botanical gardens and arboreta serve not only as a great reservior for natural resources but also as a cultural resources. They are helpful to increase the knowledge of the plants by collecting, growing, and displaying them to the community, as well as recognition of the importance of the plant world. Usually, the main functions of the university botanical gardens and arboreta are focused on research activities of plant sciences and student practice related to plant sciences. The Chonbuk National University is reponsible for establishing the university arboretum for these reasons as other universities and colleges in the world: which would serve as a scientific research bank of plant sciences and the students practicing, as well as contribute to the public both for educational and recreational purposes. In this purpose, the master plan of the Arboretum of Chonbuk National University has been prepared. Several schemes are proposed as follows to establish and develope the Arboretum of Chonbuk National University : (1) Firstly, a small sized arboretum about 20,000∼26,500㎡ will be established in the campus including whole green spaces, some nursery and greenhouses. (2) Secondary, the arboretum area will be extended to Dokjin Experiment Forests(150ha) contiguous to the campus. (3) The main tree species collected and planted in the arboretum will consist of Quercus. Acer and Rhododendron spp.. (4) Only, the positive and continuous will and efforts of the University authorities can make the best arboretum which meets everything need to both researchers and public

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