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      • KCI등재

        곰소만에 있어 바지락포자충 , Perkinsus sp. 의 출현에 관하여

        박경일(Kyung Il Park),최광식(Kwang Sik Choi),최진우(Jin Woo Choi) 한국수산과학회 1999 한국수산과학회지 Vol.32 No.3

        Mass mortality of the Manila clam, Ruditapes philippinarum has been reported all along the west and south coast of Korea for the past several years. As a pathogenic agent, Perkinsus sp., an endoparasitic protozoan has been identified in this study and believed to be responsible for the mass mortalities. Prevalence and infection intensity of Perkinsus sp. was investigated from a Manila clam population inhabiting at Komsoe Bay in the west coast where mass mortality of the clam has been reported. A total of 142 Manila clam, 50 oyster, Crassostrea gigas, 10 ark shell, Scapharca broughtonii, and 5 predatory gastropoda, Rapsna venosa were examined for the presence and the quantity of Perldnsus sp. Ray`s fluid thioglycollate medium method (FTM method) with modified Mackin`s infection intensity scale and Choi`s quantitative method were used in detecting and quantifying the parasite. All individuals of R. philippinarum examined in this study were infected with Perkinsus sp., indicaliag 100% prevalence white none of the oysters and the gastropods exhibited the parasite. Six to ten individual hypnospores of Perkinsus sp. were counted from the ark shells. The number of hypnospores in the clam tissues varied from 16,667 to 4,091,667, with a mean number of 1,077,628. Average infection intensity according to Mackin`s was 2.87, indicating a moderate infection. A negative correlation was observed between the number of Perkinsus sp. in the tissue and the condition index, a ratio tissue wet weight to shell cavity volume. The clam size and the infection intensity in terms of total number of parasites were positively correlated; the bigger clam, the heavier infection. Such high number of Perkinsus sp. counted in the clams could be enough to cause physiological disturbance of clams, such as retarded growth and reproduction. It is also believed that such a high infection leads mortality of the clam via continuous draining of the energy by metabolic activities and reproduction of the parasites. Correlation between the condition index and the infection intensity observed in this study supports this hypothesis.

      • KCI등재

        제주도 바지락에 기생하는 바지락포자충 , Perkinsus sp. 의 공간적 분포 및 조직학적 관찰

        최광식(Kwang Sik Choi),박경일(Kyung Il Park) 한국환경생물학회 2001 환경생물 : 환경생물학회지 Vol.19 No.1

        N/A The apicomplexan parasite, Perkinsus sp., has been reported as a causative pathogen responsible for the mass mortality of the Manila clams, Ruditapes philippinarum in European countries as well as in Korea. Prevalence, infection intensity, histopathologic features and zoosporulation of Perkinsus found in the Manila clams distributed along the coast of Cheju Island were investigated in this study. Clams were collected from nine different beaches along the Cheju Island from May to July in 2000. Ray`s Fluid Thioglycollate Medium(RFTM) and Choi`s NaOH lysis methods were applied in the diagnosis and quantification of the Perkinsus infection. Prevalence, percentage infection of the parasite examined was 100% in Pyosun, 70% in Sungsan, 63% in Kumneong, 33% in Jongdalri, 21% in Iho, 17% in Moslpo, and 14% in Seogwipo. No Perkinsus was found in the clams collected from Kimnyong and Yongmeo-ri. Infection intensity as a number of Perkinsus cells per gram tissue wet weight(twwt), was 98,430 cells/g twwt in Pyosun, 78,553 cells/g twwt in Sungsan, 18,980 cells/g twwt in Kumneong, 4,290 cells/g twwt in Jongdalri, 1,527 cells/g twwt in Iho, 1,069 cells/g twwt in Moslpo, and 853 cells/g twwt in Seogwipo. Histological preparation of the infected tissues revealed trophozoites of Perkinsus sp., ranged from 5 to 10㎛, in diameter mostly distibuted in the digestive gland and the gill filaments. Zoospores were discharged from the hypnospore via discharging tube about 2 days after incubated in filtered and aerated seawater. In general, the prevalence and infection intensity of Perkinsus in Cheju Island were much lower than that reported from the western and southern coast of Korea.

      • 형판정합기반 영상 정규화를 통한 고유얼굴(Eigenface)알고리즘 성능개선 방법

        최영규,신현금,장경식 한국기술교육대학교 2003 論文集 Vol.10 No.1

        A new approach for face recognition is proposed. Our method adopts the Eigenface algorithm as the main classifier, but improves performance by normalizing input images based on template matching technique. Firstly, the two eye regions are evaluated by template matching with a set of ordinary eye templates. The scale and rotation factors are estimated based on the distance and angle between left and right eyes, and we generate a normalized face of the input image, and finally, it is provided as the input of the Eigenface algorithm. Since, Eigenface is a good recognition method but is vulnerable to image variations such as rotation and illumination conditions, our face normalization approach could be very effective.

      • 液晶性 高分子 P(HBA-ET)와 PET 블렌드의 相分離 現象과 流變學的 性質

        崔景植 慶一大學校 1993 論文集 Vol.9 No.1

        The rheological properties and phase separation of the blend prepared by melt blending 60/40 mole% poly(p-hydroxybenzoic acid-co-ethylene terephthalate)[P(HBA-ET)] as thermotropic liquid crystalline polymer and poly(ethylene terphtalate)[PET] as flexible chain polymer were studied. Polarized microscopy reveals that the blends show the dynamic percolation to cluster transition phenomena during the coarsening process of spinodal decomposition at the processing temperature. At that temperature, the phase separatin of the molten blend by spinodal decomposition develops a bicontinuous, periodic domain structure with well defined interfaces. It is expected that the molten blend shows a complicated viscosity behavior and it is confirmed by measuring the rheological properties.

      • KCI등재

        Dextromethorphan HBr의 남용과 중독증 3례

        최인근,김경식 大韓神經精神醫學會 1983 신경정신의학 Vol.22 No.1

        The authors experienced 3 cases of abuse and intoxication of abuse and intoxication of dextromethorphan HBr, nonnarcotic antitussive agents. A summary of the report is as follows: dextromethorphan HBr was supposed to be abused as an euphoriant. The abusers showed toxic symptoms which were similar to those of amphetamine of anticholinergic intoxication syndromes. The symptoms of the abuse and intoxication either disappeared spontaneously or were improved by chlorpromazine in 3 to 6 days.

      • KCI등재후보

        제품디자인에서 형태와 비례의 영향에 관한 연구 : A view of Religious Culture 종교문화를 중심으로

        최명식,김경희 경희대학교 부설 디자인연구원 1999 예술· 디자인학연구 Vol.2 No.1

        This paper was written for the importance of form and propotion in products design. Specially, we connected religious culture with products design. That is, the purpose of this study was to apply religious culture to products design as human companion. Therefore, we scientifically approach why and how do we have to consider seasonal form and propotion with product design. It should itself be seen as a counterproposal that products which is applied a religious culture can join the period in the end of the century and calm down man's despondent feeling.

      • 위암환자에서 근치적 위절제술후 시행한 보조적 PMF 항암 화학요법에 대한 무작위 전향적 연구

        최우식,신연명,최경현 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

        연구 목적: 위암 수술 후 보조 항암 치료의 효과에 대하여서는 아직 논란이 있다. 전향적으로 무작위표본 추출법으로근치 절제 수술한 위암 환자에서 수술 후 cisplatin, mitomycin C 그리고 5-FU(PMF)의 주사가 5년 생존율이나 무병생존율을 증가할 수 있는지를 연구하였다. 연구 방법: 1995년 5월부터 2002년 5월까지 147명의 근치 수술된 위암 환자들 중에 병기 IB, II, IIIA, IIIB 및 IV를 대상으로 하였으나 65세 미만을 대상으로 하여 무작위적으로 2군으로 나누어, 경구 5-FU제를 투여하는 군(대조군)과, PMF 항암 주사 치료군(치료군)으로 나누어 치료하였다. 경구 5-FU항암제는 수술 후 퇴원할 시기부터 투여하였다. PMF 주사치료는 수술 후 8주 이내에 시작하며 2코스 이상 완료한 사람들을 치료군에 포함하였다. 항암 주사는 다음과 같이 진행하였다; cisplatin 30mg 정맥 주사를 제 1-5일에, mitomycin C 4mg과 5-FU 250mg정맥 주사를 주 2회 4 주간 주사하였다. 이런 주사치료를 매 4주마다 시행하였다. 이 후 5년 생존율과 무병 생존율을 Kaplan-Meier 분석과 log-rank 검정으로 구하였다. 결과: 중앙 추적기간은 36개월이었다. 전체 5년 생존율은 치료군과 대조군에서 각각 68.8%와 65.2%(p=0.26), 무병 생존율은 각각 72%와 64%(p=0.24)로 치료군에서 다소 나았으나 유의성은 없었다. 치료에 동의한 환자의 수가 적어 각 병기별 생존율보다 비교적 조기인 병기 IB와 병기 II를 A군으로, 병기 IIIA을 B군, 그리고 진행된 병기인 병기 IIIB 와 병기 IV를 C군으로 나누어 생존율 비교하여 보았다. A군과 C군은 5년 생존률이나 무병생존율의 차이가 없었으나, B군에서는 5년 생존율이 치료군에서 100%, 대조군은 40.8%(P=0.0019)로 유의한 차이가 있었고, 무병 생존율도 치료군 100%, 대조군 52.94%(p=0.005)으로 의미 있게 차이가 있었다. 항암 주사치료에 의한 부작용은 심하지 않았으며, 사망자는 없었다. 결론: 위암 수술 후 PMF에 의한 항암 보조치료는 경구 5-FU에 비하여 병기 IB, II, IIIB와 IV에서는 5년 생존율이나 무병 생존율에 차이가 없었으나 병기 IIIA에서는 5년 및 무병 생존율에 의미있게 좋았다. 앞으로 C군에 대한 수술 후 보조 항암치료법의 연구가 요망된다.

      • KCI등재후보

        명품브랜드의 제품에서 보여지는 상징색채(象徵色彩)에 관한 연구 : 명품브랜드의 핸드백 중심으로

        최명식,김경희 경희대학교 디자인연구원 2005 예술· 디자인학연구 Vol.8 No.2

        The contemporary product has to be one that has the product with certain image. Such an image is an important element to form the additional emotional value on the functional value of the product. Looking into the luxury brands in fashion, including Louis Vuitton, Gucci, Burberry, Etro, Fendi and others, they all have their own symbolic colors and texture with tradition, and consumers remember the image of symbolic color as the color image, one of the elements to form the logo and product of the visual brand before recognizing audibly for the brand. The identity as the color image that represents the brand forms the pure color and texture to have the color differentiation of its own (brand name) to maintain the identity of the symbolic color in applying the concept on the product continuously. In such a point of view, this study analyzes and studies the relativity of color and element to realize the symbolic identity of the luxury brand of fashion to develop the sensitivity and color of consumers in a way of discovering the luxury brand of Korea.

      • 광 교환 기술을 이용한 ATM 백본 네트워크

        최영복,김경연,고성택,김경식 濟州大學校 産業技術硏究所 1997 산업기술연구소논문집 Vol.8 No.2

        The B-ISDN(Broadband-Integrated Service Digital Network) transports various multimedia information effectively. So optical switching networks which consist of optical transmission links and photonic switching systems are noticeable as a way of a large capacity communication. In this paper. we propose optical packet switching networks which will be used as the backbone network of national high speed communication networks which are operated a way of ATM (Asynchronous Transfer Mode). The B-ISDN transport networks are composed of two-layered networks such as regional networks and a backbone network. The regional network is a n average ATM transport network. The optical backbone network gathers fixed length of several AThI cells which come from regional networks. attaches an optical header. and completes an optical packet, And then the network switches and transports with high speed. That is. the backbone network is a transparent optical packet network. The passing speed of signal in the photonic switch is rapid, but the switching speed is limited and the processing speed of the switching controller which consists of electronic circuit is limited. So the optical packet which consists of multi-ATM cells is able to overcome it in the optical backbone network. The performance evaluation by the computer simulation shows us the efficiency of the proposed way of optical packet switching.

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