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Clinical benefit of nomogram for predicting positive resection margins in breast conserving surgery
Lee, E.-S.,Han, W.,Shin, H.-C.,Takada, M.,Ryu, H.S.,Cho, N.,Kim, M.K.,Kim, J.,Yoo, T.-k.,Moon, H.-G.,Toi, M.,Moon, W.K.,Park, I.-A.,Noh, D.-Y. Elsevier 2016 European journal of surgical oncology Vol.42 No.8
<P>Purpose: Previously, we reported a nomogram for the prediction of positive resection margin (RM) after breast conserving surgery (BCS). This study was conducted to evaluate the clinical usefulness of the nomogram. Methods: Prospective patients who underwent operations using the nomogram between July 2012 and August 2013 (nomogram group; N = 260) were compared with past control patients who underwent operations between July 2010 and October 2011 and underwent frozen section biopsy (FSB) without use of the nomogram (N = 266). In the nomogram group, an intraoperative assessment of RM using FSB was only performed when the nomogram score was higher than predefined cut-off (>80). In addition, we conducted retrospective analysis of additional 181 patients who received BCS in another institute (Kyoto University Hospital). These patients did not undergo FSBs for RMs. Results: Of 260 patients, 161 (61.9%) presented low nomogram scores and avoided FSB. The surgical decision to use the nomogram did not significantly increase reoperation rate due to positive RM compared with the control FSB group (4.6% vs. 3.8%, p = 0.47). The surgery time was significantly reduced by 18.1% (mean 14.7 min) in nomogram group (p < 0.001). Of 99 nomogram high-score patients, 14 presented with positive RM on FSB and 11 of them avoided reoperation. In the Kyoto cohort, the reoperation rate was significantly lower in low-score patients than in high-score patients (2.7% vs. 11.4%, p < 0.001). Conclusions: We showed that our nomogram is useful to reduce FSBs without increasing reoperation rate for surgeons who perform routine FSBs. For most surgeons, it can give useful information about the possibility of tumor-positive RMs. (C) 2016 Elsevier Ltd. All rights reserved.</P>
Plasma-Confinement Physics Study in Compact Helical System
stoichi Okamura,A. Fujisawa,A. Shimizu,C. Takahashi,C. Suzuki,H. Iguchi,H. Nakano,H. Matsushita,K. Nagaoka,K. Matsuo,K. Ida,K. Toi,K. Nakamura,K. Matsuoka,M. Yoshinuma,M. Isobe,M. Takeuchi,R. Ikeda,S. 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.III
In a CHS experiment, various types of transport barrier have been studied. An internal transport barrier (ITB) for electrons in a stellarator was first found in CHS, and the ITB for improved ion confinement was also found. H-mode (edge transport barrier) study in CHS showed many common features in transition to tokamak experiments, although the magnetic surface quantities are very different. Discharges with a combination of ETB and ITB were also found. Two heavy ion beam diagnostics in CHS showed a new direct measurement of zonal flow structure in toroidal confinement. The relation between the fluctuation and the transport barrier was also studied.
Two Dimensional Measurement of Electron Density in LHD plasmas by Sheet-Shaped Thermal Lithium-Beam
yoshiyuki Takahashi,K. Toi,T. Morisaki 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.III
In the Large Helical Device (LHD), of which the magnetic surfaces are surrounded by a complicated ergodic magnetic field layer, two dimensional measurement of electron density was carried out by using a thermal lithium beam shaped into a sheet extended along the major radius. The thermal lithium beam having a sheet shape was produced in a simple way, the lithium vapor was passed through three orifices placed in front of an aperture of an oven, and was injected vertically into the LHD plasma. Two dimensional images of LiI emission were obtained by using a CCD camera with an interference filter for the LiI spectral line. A two dimensional profile of electron density near the plasma edge region was successfully derived from the LiI emission image.
ryosuke Ikeda,C. Suzuki,G. Matsunaga,K. Toi,M. Takeuchi,S. Okamura 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.III
For the purpose of transport simulation, low temperature plasmas having similar dimensionless parameters to those of high temperature plasmas are produced by 2.45 GHz microwaves up to and 30 kW at low toroidal field (Bt < 0.1 T) in the Compact Helical System (CHS). In the configuration where the fundamental electron cyclotron resonance layer is placed near the last closed flux surface, electron density exceeds the ordinary (O)-mode cutoff density by a factor of 2 . 3 in hydrogen plasmas. The deposition of microwave power occurs in the interior region beyond the (O)-mode and extraordinary (X)-mode cutoff layers through which electron cyclotron waves (ECW) cannot penetrate. This suggests that a mode conversion of ECW to electron Bernstein wave (B-mode) would occur. Moreover, superimposition of ECW power was performed on target over-dense plasmas which have a steep density gradient at the upper hybrid resonance layer. In this condition, the mode conversion efficiency of superimposed ECW power was theoretically estimated to be about 50 . 60 %. The absorption rate of superimposed ECW power reached up to about 30 %.