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      • KCI등재

        구개부에 발생한 다형선종의 처치

        하주원,백승,송종운,박충열,이용욱,박홍주,오희균,유선열,김옥준 大韓顎顔面成形再建外科學會 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.6

        Pleomorphic adenoma of the palate is the most common of all intraoral salivary tumors. It can occur at any age but it presents most commonly in the 40∼60 age group, and there is no significant sex preponderance. It grows slowly and is usually painless, firm, well-circumscribed nodule. Because of high rate of recurrence, extra-capsular excision including the overlying mucosa and margin of normal tissue is recommended. We report 10 cases of palatal pelomorphic adenoma which have been successfully treated by extra-capsular excision. The surgical defects smaller than 3㎝ in diameter were covered with palatal acrylic splint for the secondary healing. The larger defects were repaired using palatal island flap in 3 cases, rotation flap and buccal fat graft in each 1 case. No patient showed any recurrence or malignant change during the mean follow-up period of 4 years and 9 months. These repair methods seem to be simple, reliable and uncomplicated procedures in the palatal surgical defects.

      • KCI등재후보

        가토에서 Pentoxifylline, Asprin 및 Heparin이 피부피판의 생존 및 출혈 경향에 미치는 영향

        하주원,백승,박홍주,오희균,유선열 大韓顎顔面成形再建外科學會 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.5

        The skin flap, which has been frequently used in the maxillofacial soft tissue defects, can be failed due to insufficient blood supply to the flap. To increase its survival rate, antithrombotic agents has been used. The agents have, however, been restrictly used because of their side effects, such as bleeding tendency or hematoma formation on the operation site. The present study aimed to the effect of pentoxifylline, aspirin, and heparin on the skin flap survival rate and bleeding tendency. Twelve adult white rabbits, weighing about 2.0 ㎏, were used. Five random skin flaps, which is 1㎜ thickness, were prepared on the dorsal surface of each rabbit by using 1.5×7.5㎝ prefabricated template. The animals were divided into 4 groups on the basis of drugs used: Control group, animals in which no drug was given (n=3); Pentoxifylline group, animals in which pentoxifylline was given intraorally (n=3); Aspirin group, animals in which aspirin was given intravenously (n=3), and Heparin group, animals in which heparin was given intravenously (n=3). On the 3rd and 7th day after operation, prothrombin time (PT) and activated partial thromboplastin time (aPTT) were measured to evaluate the bleeding tendency. The animals were sacrificed on the 7th day and the mean skin falp survival rate of each group was measured. The results obtained were as follows : The skin flap survival rates of pentoxifylline (84.3±7.9%) and heparin (79.5±10.9%) groups were significantly increased, compared with control group (68.0±10.8%)(P<0.05). The survival rate of aspirin group (73.0±11.1%) was not increased. In bleeding tendency, the PT values were prolonged in heparin and aspirin groups at the 3rd day after operation (P<0.05), and prolonged in order of heparin group, aspirin group, and pentoxifylline group at the 7th day after operation. The aPPT values in heparin and aspirin groups were also prolonged at the 3rd day after operation (P<0.05), and prolonged in order of Aspirin group, Heparin group, and Pentoxifylline group at the 7th day after operation. These results suggest that pentoxifylline may be the most useful drug among three drugs to increase skin falp survival rate and less increase the bleeding tendency.

      • 가토에서 Pentoxifylline, Aspirin 및 Heparin이 피부피판의 생존 및 출혈 경향에 미치는 영향

        하주원,백승,박홍주,오희균,유선열 전남대학교 치의학연구소 2002 구강과학 Vol.14 No.2

        The skin flap, which has been frequently used in the maxillofacial soft tissue defects, can be failed due to insufficient blood supply to the flap. To increase its survival rate, antithrombotic agents has been used. The agents have, however, been restrictly used because of their side effects, such as bleeding tendency or hematoma formation on the operation site. The present study aimed to the effect of pentoxifylline, aspirin, and heparin on the skin flap survival rate and bleeding tendency. Twelve adult white rabbits, weighing about 2.0 kg, were used. Five random skin flaps, which is 1mm thickness, were prepared on the dorsal surface of each rabbit by using 1.5 X 7.5 cm prefabricated template. The animals were divided into 4 groups on the basis of drugs used: Control group, animals in which no drug was given (n=3); Pentoxifylline group, animals in which pentoxifylline was given intraorally (n=3); Aspirin group, animals in which aspirin was given intravenously (n=3). On the 3rd and 7th day after operation, prothrombin time (PT) and activated partial thromboplastin time (aPTT) were measured to evaluate the bleeding tendency. The animals were sacrificed on the 7th day and the mean skin flap survival rate of each group was measured. The results obtained were as follows : 1. The skin flap survival rates of pentoxifylline (84.3±7.9%) and heparin (79.5±10.9%) groups were significantly increased, compared with control group (68.0±10.8%)(ㅔ<0.05). The survival rate of aspirin group (73.0±11.1%) was not increased. 2. In bleeding tendency, the PT values were prolonged in heparin and aspirin groups at the 3rd day after operation (p<0.05), and prolonged in order of heparin group, aspirin group, and pentoxifylline group at the 7th day after operation. The aPPT values in heparin and aspirin groups were also prolonged at the 3rd day after operation (p<0.05), and prolonged in order of Aspirin group. Heparin group, and Pentoxifylline group at the 7th day after operation. These results suggest that pentoxifylline may be the most useful drug among three drugs to increase skin flap survival rate and less increase the bleeding tendency.

      • KCI등재후보

        이하선 종양에 관한 임상적 연구

        백승,하주원,오희균,유선열,김원재 大韓顎顔面成形再建外科學會 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.5

        This is clinical study on 113 patients who were treated for parotid tumors at Chonnam National University Hospital over a period of 5 years from January 1996 to December 2000. The results were as follows ; The mean ages were 42.6 years old (12∼73 years) for benign parotid tumor patients and 43.9 years old (2∼74 years) for malignant patients. The ratio of male to female was 1:2 in malignant parotid tumors, but there was no difference in benign tumors. There was no difference in mean mass size and duration of illness between benign and malignant tumor patients. The combined usage of fine needle aspiration biopsy and computed tomogram was common as the diagnostic methods of parotid tumor. The parotid tumors were commonly located in the superficial lobe (69%). The ratio of benign and malignant tumors was 4:1. The most common benign tumor was pleomorphic adenoma (72% of benign tumor), followed by Warthin's tumor and monomorphic adenoma. The most common malignant tumor was mucoepidermoid carcinoma (45% of malignant tumor), followed by adenoid cystic carnoma, carcinoma ex pleomorphic adenoma, and adenocarcinoma. The most common operations were superficial parotidectomy (72%) for benign parotid tumor and total parotidectomy (45%) for malignant tumor. The most common postoperative complication was temporary facial nerve weakness (82%), followed by Frey's syndrome (14%) and permanent facial palsy (4%). Postoperative radiation therapy was done in 12 patients (60%) and the mean radiation dose was 5550±620 cGy. Of 113 cases, tumor recurrence developed in 12 cases (10%). These results suggest that the successful management of parotid gland tumors needs adequate surgical treatment on the basis of knowledge of parotid gland anatomy and preoperative diagnosis.

      • 사과 개화기 저온피해 최소화를 위한 간헐적 미세살수 방법

        오주열(Ju Youl Oh),김현수(Hyun Soo Kim),손진향(Jin Hyang Son),구소희(So Hee Gu),김윤숙(Yun Sook Kim),홍정진(Jeong Jin Hong),정은호(Eun Ho Jeong) 한국원예학회 2021 한국원예학회 학술발표요지 Vol.2021 No.10

        사과 개화기 이상기상에 의한 저온으로 사과 꽃의 저온피해 및 착과된 과실의 조기낙과 피해가 매년 심각하게 발생하고 있는 실정이다. 경남지역에서는 2018년 514ha, 2020년 720ha, 2021년 1,200ha 정도가 개화기 이상기상에 의한 저온피해를 받은 것으로 보고 되고 있다. 개화기 저온피해 방지를 위한 방법으로 송풍법, 살수법, 연무법, 연소법 등이 기술적으로 개발되어 있으나 초기 투자비용, 환경, 작업성 등에서 제약이 있어 적극적으로 권장 활용하지를 못하고 있다. 저온피해를 최소화 하는 방법 중 살수법이 가장 효과적인 것으로 알려져 있으며 이는 물이 얼 때 발생하는 잠열을 이용하는 방법으로 살수하는 동안 충분한 물이 공급 되어야 그 효과를 극대화 할 수 있다. 이러한 살수방법은 노즐의 종류, 물의 공급압력, 살수반경, 살수 시작시점과 종료시점에 따라 물 사용량이 최대 10배 이상 차이가 날 수 있다. 사과 과원 저온피해 최소화를 위한 살수 노즐의 선발과, 살수 시점의 자동화를 위한 온도 설정에 대한 기존 연구를 바탕으로 물 사용량을 효과적으로 줄일 수 있는 방법을 구명하고자 본 시험을 수행하였다. 경남농업기술원 사과이용연구소 0.7(W) × 0.7(D) × 1(H)m의 용기에 식재된 ‘후지’/M9 품종을 2021년 4월 13일부터 4월 20일까지 중심화 개화~만개기일때 플리프 노즐(Purple + Brown + Brown), 관수 타이머, 관수량 측정시스템을 설치 하고 온도제어가 되는 저온 저장고에서 실시하였다. 미세살수는 1°C에서 시작하고 온도는 –4°C에서 4시간을 유지하도록 하였으며 간헐적 살수 방법은 살수유지/살수중지 시간을 10분/10분, 20분/10분, 30분/10분, 연속살수와 살수를 하지 않고 –4°C에서 4시간을 노출시키는 무살수 5처리를 두고 실시하였다. 살수처리에서는 꽃의 배주 생존율이 27%~47% 정도 보였지만 –4°C에서 4시간 무살수 처리에서는 2.1%의 생존율 보였다. 저온 처리 30일 후 화총대비 착과율에서는 살수 처리에서는 3.2%~12.9%의 착과율을 보였지만 무살수 처리에서는 0%의 착과율을 보였다. 물 사용량은 연속살수 처리에서 가장 많은 133L(노즐 1개)의 물을 사용하였고 간헐적 살수 10분/10분 처리에서 가장 적은 77.5L(노즐 1개) 물을 사용하였다. 저온피해 최소화를 위한 간헐적 살수는 연속살수 대비 물의 사용량은 줄이고 꽃의 저온피해와 착과율에서 유사한 경향을 보여 수자원이 풍부하지 못한 농가에서는 활용 가능성이 높은 방법으로 판단되어 진다. 하지만 간헐적 살수간격의 살수중지 시간을 10분 이상 하게 되면 최저기온에 따라 노즐 끝부분의 배관에 얼음이 생길 수 있어 살수중지 시간의 길이는 원수 온도와 최저기상 온도에 따라 조절이 필요하다.

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