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      • New and interesting species in the family <i>Graphidaceae</i> (Ascomycota: <i>Ostropales</i>) from Vietnam

        JOSHI, Santosh,UPRETI, Dalip K.,THANH, Nguyen Thi,NGUYEN, Anh Dong,HUR, Jae-Seoun Cambridge University Press 2017 The Lichenologist Vol.49 No.3

        <B>Abstract</B><P>The lowland area of southern Vietnam contains a high diversity of corticolous, crustose lichens, particularly in the family <I>Graphidaceae</I>. Two species, <I>Acanthothecis verrucosa</I> S. Joshi, Upreti & Hur and <I>Graphis exuta</I> S. Joshi, Upreti & Hur, are described new to science. <I>Acanthothecis verrucosa</I> is characterized by a verrucose, olive green thallus containing irregular to shortly lirellate apothecia, hyaline to brownish proper exciple apically lined by robust periphysoids, muriform ascospores, 30-70 × 15-20 μm, and the presence of psoromic and subpsoromic acids. <I>Graphis exuta</I> is characterized by a smooth, greenish white thallus, simple lirellae lacking thalline margin, entire labia coarsely white pruinose towards slit, muriform ascospores, 20-35×10-13 μm, and norstictic acid in the thallus. A new name, <I>Acanthothecis yokdonensis</I> S. Joshi & Hur, is proposed here for the species <I>Acanthothecis salazinica</I> S. Joshi & Hur, a later homonym of <I>A. salazinica</I> van den Boom & Sipman. In addition, 34 species from Vietnam are newly reported. A world key to the group of <I>Graphis</I> species characterized by short, simple and sessile lirellae lacking or with basal thalline margins (<I>nuda</I>-morph) is presented.</P>

      • SCIESCOPUSKCI등재

        Comparative evaluation of NovaMin desensitizer and Gluma desensitizer on dentinal tubule occlusion: a scanning electron microscopic study

        Joshi, Surabhi,Gowda, Ashwini Shivananje,Joshi, Chintan Korean Academy of Periodontology 2013 Journal of Periodontal & Implant Science Vol.43 No.6

        Purpose: In this study, the effect of calcium sodium phosphosilicate (NovaMin) desensitizing agent, which is a powder-based system, and hydroxyethyl methacrylate and glutaraldehyde (Gluma desensitizer), which is liquid-based system, on dentinal tubule occlusion was analyzed by scanning electron microscope. The effects of the above two along with one control group were compared to determine the more effective method of sealing the dentinal tubules after initial application. Methods: Twenty specimens were allocated to each of 3 groups: Control, Gluma desensitizer, and NovaMin. Two additional samples were also prepared and treated with Gluma and NovaMin; these samples were longitudinally fractured. The specimens were prepared from extracted sound human premolars and were stored in 10% formalin at room temperature. The teeth were cleaned of gross debris and then sectioned to provide one to two dentin specimens. The dentin specimens were etched with 6% citric acid for 2 minutes and rinsed in distilled water. Control discs were dried, and the test discs were treated with the desensitizing agents as per the manufacturer's instructions. The discs as well as longitudinal sections were later analyzed under the scanning electron microscope. The proportions of completely occluded, partially occluded, and open tubules within each group were calculated. The ratios of completely and partially occluded tubules to the total tubules for all the groups was determined, and the data was statistically analyzed using nonparametric tests and statistical significance was calculated. Results: NovaMin showed more completely occluded tubules ($0.545{\pm}0.051$) while Gluma desensitizer showed more partially occluded tubules ($0.532{\pm}0.075$). The differences among all the groups were statistically significant ($P{\leq}0.05$). Conclusion: Both materials were effective in occluding dentinal tubules but NovaMin appeared more promising in occluding tubules completely after initial application.

      • KCI등재

        A Brief Review on Murraya paniculata (Orange Jasmine): pharmacognosy, phytochemistry and ethanomedicinal uses

        Joshi Deepa,Kashmira J.Gohil,Joshi Deepa 대한약침학회 2023 Journal of pharmacopuncture Vol.26 No.1

        Objectives: Murraya paniculata (family-Rutaceae), popularly known as orange jasmine, is the most important evergreen plant. The Rutaceae family is economically significant due to its diverse edible fruits and essential oils. Methods: Murraya paniculata extracts (MPE) of leaf have been shown to include phenolic compounds, highly oxygenated flavonoids, flavanones, sesquiterpenoids, polymethoxy glycosides, and coumarins. Cyclocitral, methyl salicylate, trans-nerolidol, cubenol, isogermacrene, -cadinol, and cubeb-11-ene are all abundant in MPE. The usages of various parts of this plant, such as bark, leaves and flower, as a remedy for a variety of ailments as widely recorded in the traditional literature. The plant has anti-diabetic, anti-obesity, antibacterial, anti-implantation, anti-oxidative, cytotoxic, anti-diarrheal, antidepressant and anti-anxiety properties and many others. Results: The goal of the review is to reignite interest in this potential plant, encouraging researchers to continue their research in order to uncover novel therapeutic compounds for the treatment and management of a range of infections. The current review provided a comprehensive overview of this traditional unique plant. Conclusion: The review paves a way for exploring its active chemical elements with substantial pharmacological values further for potential benefits of mankind.

      • SCOPUSKCI등재

        Silica Sulfuric Acid as a Mild and Efficient Reagent for the Synthesis of 1,4-Diazepine and 1,5-Benzodiazepine Derivatives

        Joshi, Y.C.,Saingar, Shalini,Kavita, Kavita,Joshi, P.,Kumar, Rajesh Korean Chemical Society 2011 대한화학회지 Vol.55 No.4

        The synthesis of biologically active 1H-1,4-diazepines 4a-d and 3H-1,5-benzodiazepines 5a-d in good yields, from the heterocyclization reaction of 2-(4-methylthio benzenesulfonyl)-1,3-dimethyl/1-methyl-3-phenyl/1,3-diphenyl/1-methyl-3-ethoxy propane-1,3-dione 3a-d with ethylenediamine (EDA) and o-phenylenediamine (o-PDA), respectively, in the presence of silica sulfuric acid (SSA) is described. The novel ${\beta}$-diketones/${\beta}$-ketoesters 3a-d were synthesized by the condensation reaction of 4-methylthiobenzenesulfonyl chloride 1 with various ${\beta}$-diketones/${\beta}$-ketoesters 2a-d. All structures of the newly synthesized compounds were elucidated by elemental analysis and spectral studies. The compounds 4a-d and 5a-d have been screened for antimicrobial, antifungal and anthelmintic activity. Silica sulfuric acid (SSA)를 이용하여 ethylenediamine (EDA)과 o-phenylenediamine (o-PDA)을 2-(4-methylthio benzenesulfonyl)-1,3-dimethyl/1-methyl-3-phenyl/1,3-diphenyl/1-methyl-3-ethoxypropane-1,3-dione 3a-d과의 헤테로고리화 반응을 통하여 좋은 생리활성을 나타내는 1H-1,4-diazepines 4a-d과 3H-1,5-benzodiazepines 5a-d을 좋은 수율로 합성하였다. 이 반응에서 ${\beta}$-diketones/${\beta}$-ketoesters 3a-d는 4-methylthiobenzenesulfonyl chloride 1과 다양한 ${\beta}$-diketones/${\beta}$-ketoesters 2a-d과의 축합반응으로 합성하였으며, 합성한 4a-d와 5a-d 화합물들에 대해서 fantimicrobial, antifungal 및 anthelmintic 활성을 측정하였다.

      • Insulin-like Growth Factor-1, IGF-binding Protein-3, C-peptide and Colorectal Cancer: a Case-control Study

        Joshi, Pankaj,Joshi, Rakhi Kumari,Kim, Woo Jin,Lee, Sang-Ah Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9

        Context: Insulin-like growth factor peptides play important roles in regulating cell growth, cell differentiation, and apoptosis, and have been demonstrated to promote the development of colorectal cancer (CRC). Objective: To examine the association of insulin-related biomarkers including insulin-like growth factor-1 (IGF-1), insulin-like growth factor binding protein-3 (IGFBP-3) and C-peptide with CRC risk and assess their relevance in predictive models. Materials and Methods: The odds ratios of colorectal cancer for serum levels of IGF-1, IGFBP-3 and C-peptide were estimated using unconditional logistic regression models in 100 colorectal cancer cases and 100 control subjects. Areas under the receiving curve (AUC) and integrated discrimination improvement (IDI) statistics were used to assess the discriminatory potential of the models. Results: Serum levels of IGF-1 and IGFBP-3 were negatively associated with colorectal cancer risk (OR=0.07, 95%CI: 0.03-0.16, P for trend <.01, OR=0.06, 95%CI: 0.03-0.15, P for trend <.01 respectively) and serum C-peptide was positively associated with risk of colorectal cancer (OR=4.38, 95%CI: 2.13-9.06, P for trend <.01). Compared to the risk model, prediction for the risk of colorectal cancer had substantially improved when all selected biomarkers IGF-1, IGFBP-3 and inverse value of C-peptide were simultaneously included inthe reference model [P for AUC improvement was 0.02 and the combined IDI reached 0.166% (95 % CI; 0.114-0.219)]. Conclusions: The results provide evidence for an association of insulin-related biomarkers with colorectal cancer risk and point to consideration as candidate predictor markers.

      • KCI등재
      • KCI등재

        Effects of the storage environment on the quality attributes of eggs with a washing treatment

        Ritu Joshi,Rahul Joshi,Mohammad Akbar Faqeerzada,박은수,배형진,이재용,이재영,김현태,조병관 충남대학교 농업과학연구소 2019 Korean Journal of Agricultural Science Vol.46 No.3

        The term quality or freshness of eggs in industrial production still poses concerns regarding whether washing is necessary. Therefore, the aims of this study were to examine the effects of different storage times and temperatures and to perform a comparison between washed and unwashed eggs. A total of 1000 washed and 1000 unwashed egg samples were stored at three different temperatures (5, 10, and 25℃) for 0 - 8 weeks and were used for the data collection. On the designated day, the eggs were processed to evaluate their internal and external quality traits, such as the Haugh unit, airspace volume, eggshell strength, pH, and microbiological profile. Significant differences (p < 0.05) were observed between the washed and unwashed eggs for each quality trait. The results indicate that storage between 5 and 10℃ better preserved the quality of eggs compared with the storage at 25℃ throughout the days of the storage. Overall, this study suggests that the storage time and temperature have a vital role in maintaining the quality of eggs which were significantly affected during storage. In addition, all the quality parameters differed between the washed and unwashed samples which is further responsible for deteriorating the quality of the eggs.

      • Rapid Evaluation of Lead Oxide Contamination in Paprika Powder using Raman Spectroscopy

        ( Ritu Joshi ),( Rahul Joshi ),( Byoung-kwan Cho ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

        Color is an important quality parameter in spices as it indicates the freshness and purity of spices which losses due to over time that makes it as a major target of adulteration. Paprika powder is used as an ingredient in numerous dishes around the world. Lead oxide, used as a contaminant in paprika powder for influencing the color. When consume it can easily dissolve in the hydrochloric acid present in our stomach, making it toxic upon ingestion. In this work, the feasibility of using Raman spectroscopy for rapid determination of lead oxide in paprika powder was investigated. Raman spectra in the 350-1600 cm<sup>-1</sup> region were collected for 120 paprika samples spiked with lead oxide have the concentrations: 0 (pure paprika powder), 0.02, 0.04, 0.06, 0.08 and 0.1 %, respectively. The calibration and validation data sets were designed using data from 72 and 48 samples, respectively. Developed partial least square regression (PLSR) model was applied to all collected spectral data of pure and adulterated paprika powder samples. Model-based variable selection methods combined with variable importance in projection (VIP) values and significance multivariate correlation (sMC) used to explore the optimal variables important for the predictability of adulteration. The PLSR predictive value for the sMC-based model presented a correlation coefficient value with a standard error of prediction (SEP) of 0.008%, improved than the models developed with all variables (and SEP = 0.01%) or VIP-selected variables ( and SEP = 0.009%).Thus, the obtained experimental results indicates that the proposed technique can be regarded as an effective tool compare to conventional methods for the quantitative determination of lead oxide in paprika powder.

      • KCI등재

        A comparison of ATR-FTIR and Raman spectroscopy for the non-destructive examination of terpenoids in medicinal plants essential oils

        Rahul Joshi,Sushma Kholiya,Himanshu Pandey,Ritu Joshi,Omia Emmanuel,Ameeta Tewari,김태현,조병관 충남대학교 농업과학연구소 2023 Korean Journal of Agricultural Science Vol.50 No.4

        Terpenoids, also referred to as terpenes, are a large family of naturally occurring chemical compounds present in the essential oils extracted from medicinal plants. In this study, a nondestructive methodology was created by combining ATR-FT-IR (attenuated total reflectance- Fourier transform infrared), and Raman spectroscopy for the terpenoids assessment in medicinal plants essential oils from ten different geographical locations. Partial least squares regression (PLSR) and support vector regression (SVR) were used as machine learning methodologies. However, a deep learning based model called as one-dimensional convolutional neural network (1D CNN) were also developed for models comparison. With a correlation coefficient (R2) of 0.999 and a lowest RMSEP (root mean squared error of prediction) of 0.006% for the prediction datasets, the SVR model created for FT-IR spectral data outperformed both the PLSR and 1 D CNN models. On the other hand, for the classification of essential oils derived from plants collected from various geographical regions, the created SVM (support vector machine) classification model for Raman spectroscopic data obtained an overall classification accuracy of 0.997% which was superior than the FT-IR (0.986%) data. Based on the results we propose that FT-IR spectroscopy, when coupled with the SVR model, has a significant potential for the non-destructive identification of terpenoids in essential oils compared with destructive chemical analysis methods.

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