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서중석 大韓法醫學會 2000 대한법의학회지 Vol.24 No.1
Carbon monoxide which is an odorless, colorless, non-irritating gas causes asphyxia by blocking the hemoglobin of the RBC from carrying oxygen to the tissues and from returning carbon dioxide to the lungs. The clinical symptoms of CO poisoning depend on the blood CO saturation level and in a healthy middle-aged individual a blood CO saturation greater than 50% is considered fatal. In forensic science, the investigation of the scene in cases of CO poisoning is imperative to determine the manner of death or the source of CO production, while postmortem diagnosis of CO poisoning is not difficult. The author reported four cases of CO poisoning in the unusual or atypical circumstances, which were no recognized in the scene.
서중석,이우승,김현,김호덕,라봉진 중앙대학교 의과대학 의과학연구소 1998 中央醫大誌 Vol.23 No.4
It has been demonstrated that brief period of ischemia and reperfusion (ischemic preconditioning, IP) enhances recovery of post-ischemic contractile dysfunction and reduces incidences of reperfusion-induced arrhythmia or infarct size after a prolonged ischemia. Recent studies suggest that IP triggers activation of protein kinase C (PKC). In the present study, the author teated this hypothesis with PKC activator, phorbol ester (PMA, 0.01 nM) or inhibitor, calphostin C (200 nM) to measure the left ventricular function and infarct size; and assessed whether hemodynamics are related with each other or not. Hearts isolated from New Zealand White rabbits (1.5-2.0 kg body weight) were perfused with Tyrode solution by Langendorff technique. After stabilization of baseline hemodynamics, the hearts were subjected to 45 min global ischemia followed by 120 min reperfusion with IP (IP group, n=7) or without IP (ischemic control group, n=7). IP was induced by single episode of 5 min global ischemia and 10 min reperfusion. In the PMA-treated group (n=13), the heart was subjected to perfusion with Tyrode solution containing PMA for 5 min after stabilization of the baseline, washing out (for 10 min with normal perfusion), and 45 min ischemia and 120 min reperfusion; in the calphostin C-treated preconditioned group (n=15), calphostin C was given for 15 min from 5 min before IP regimen. Left ventricular function including developed pressure (LVDP), dP/dt, heart rate, left ventricular end-diastolic pressure (LVEDP) and coronary flow (CF) was measured. Iinfarct size was determined by staining with tetrazolium salt and planimetry. Data were anaalyzed by one-way analysis of variance and Tukey's post-hoc test; and linear regression between hemodynamic values. In comparison with the ischemic control group, IP signifivantly increased the recovery of the left ventricular function including left ventricular developed pressure, contractility, and coronary flow. However, enhancement of the functional recovery disappeared by calphostin C or PMA treatment. IP and PMA also reduced infarct size (from 38 to 10-20%, p<0.05). However, calphostin C blocked infarct reduction effect of IP. These results suggest that in isolated Langendorff-perfused rabbit heart model, IP could improve post-ischemic contractile dysfunction, as well as it has an infarct size-liniting effect; these cardioprotective effect of IP may be related, at least in part, to trigger activation of PKC, however, there are any relationship between hemodynamics.
서정헌,박서영,곽중민,강인석 경상대학교 생산기술연구소 2002 工學硏究院論文集 Vol.2 No.-
Recently, our construction industry is using various work sections classification systems for civil engineering projects. However, because the public IDB(Integrated DataBase) for the work sections is insufficiently built, it is difficult to connect construction operation information from construction site to standard specification or standard method of measurment. Therefore, this study suggests a methodology to link the construction work sections information, such as cost, schedule, drawings and specification, with civil engineering standard method of measurement. And the methodology suggested in this study was applied to a web-based work sections information management system with IDB. An IDB modeling was designed by using DFD (Data Flow Diagram) and ERD (Entity Relationship Diagram).
서중석,강신몽 大韓法醫學會 1996 대한법의학회지 Vol.20 No.2
During the last few years the traumatic basal subarachnoid hemorrhage(SAH) has been recognized that blows to the neck, head and face can give rise to fatal SAH because of tearing of the intrathecal course of a vertebral artery or basilar artery. No doubt a number of SAH are due to rupture of non-aneurysmal vessels or aneurysm too small to find, but unrecognized vertebral artery trauma would have accounted for remainder. In these cases, there may be no external sign at all. Unfortunately the deep or lateral portion of neck is the area that is not routinely dissected at autopsy. This is probably why this syndrome was not recognized until a few years ago. The mechanisms of injury and hemorrhage have been inadequately explored and demonstrated due to absence of appropriate and adequate anatomic dissection. According to the current literature on the traumatic basal SAH, the cause of death is now hypothesized to have been a tear in the vertebral artery associated with hyperextension and rotation.
강인석,곽중민,박서영,이동희,김창학 경상대학교 생산기술연구소 2001 工學硏究院論文集 Vol.1 No.-
The current trend of If (Information Technology) in 21st century demands management innovation, that is Business Process Reengineering (BPR) in all the industry including construction project. The solution of its demand is proposed by IT based on Internet. And also, in order to meet this objective, from 1997 domestic construction industry is accelerating to systematize CALS (Continuous Acquisition and Life-cycle Support) which is being planned to apply by government. These efforts give much weight to build computer systems rather than to improve and redesign construction business process that is more important for system application. This research develops a model for applying the BPR to construction industry, especially construction site that is a base to build a system for CALS. And the research suggests performing method, process and modeling technique of BPR to be applicable in business process redesign of construction field. Also, focusing on the research of execution step of business in construction site will be helpful for the site worker to perform BPR in construction site.