http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Lee, Jongwook,Kim, Junki,Ahn, Jaehong,Woo, Woontack Elsevier 2019 Journal of cultural heritage Vol.38 No.-
<P><B>Abstract</B></P> <P>This research proposes a data structure for context-aware risk management for architectural heritage using Historic Building Information Modeling (HBIM) and Virtual Reality (VR). In cultural heritage domain, risk management plays a key role in the preservation and intervention of the heritage. For effective risk management, it is important to share enriched data between people who monitor and diagnose heritages and people who recognize the context of information. The 5W1H (what, when, where, who, why, and how) model-based metadata structure for context-awareness and the framework for linking the HBIM with VR environment which enables sharing and retrieving of risk management information are proposed in this research. Two prototypes were created; an on-site VR application for the heritage managers and a remote VR application for the conservators. The effectiveness of the applications was verified through an experiment including a user survey to compare the paper-based and the VR-based methods regarding on-site VR application, and a focus-group interview regarding the remote VR application. This study enabled to integrate risk management information scattered across a variety of sources and formats, provide contextualized information. Thereby it shortens the time and effort spent to find and share information by heritage managers and conservators.</P>
( Jongwook Oh ),( Ro Woo Lee ),( Hee Ra Lee ),( Seon Bok Lee ),( Hyun Jeong Ju ),( Jungwon Park ),( Hee Ryun Park ),( Ji Hun Park ),( Seung-kyung Hann ),( Abdurrahman Almurayshid ),( Jeonghyun Shin ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1
Background: The classification of segmental vitiligo has been previously reported but more consensus on its classification is required from a large number of patients to predict its spreading and provide valuable clues to the etiology of segmental vitilig. Objectives: To classify segmental vitiligo on the whole body into several distinctive subtypes according to distributions and clinical characteristics. Methods: Total 956 patients with segmental vitiligo were enrolled. A new classification of has been proposed according to distribution patterns. The clinical course of segmental vitiligo, including recurrence rate and patterns, concurrence of non-segmental vitiligo, and treatment response, was assessed. Results: Facial and truncal segmental vitiligo was classified into each 5 patterns. Among 501 patients who had been followed up for at least one year, 55 patients (11%) showed recurrence after stabilization for more than 6 months. Most recurrence happened within the area of each subtype of segmental vitiligo in the new classification (92.7%). Conclusion: Our data suggest that segmental vitiligo has a higher recurrence rate than previously known. This new classification can help dermatologists in patient’s real care
( Jongwook Oh ),( Won Seok Roh ),( Tae-gyun Kim ),( Seung-tae Lee ),( Min-geol Lee ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1
Background: Generalized pustular psoriasis(GPP) is a rare, sudden onset, life-threatening disease characterized by recurrent flares of pustular, erythematous rashes. Objectives: To find out difference in clinical characteristics of Korean GPP patients with genetic mutation. Methods: In this study, we conducted series of targeted gene sequencing of 9 Korean patients with GPP(M:F=4:5). Six out of 9 patients had IL36RN, CARD14, or APS mutations. Results: For mutations in IL36RN gene, we found two homozygous (c368C>T, c115+6T>C), two compound heterozygous (c115+6T>C/c28C>T), and two heterozygous (c115+6T>C, c245C>T) mutations in 6 patients. Patients with homozygous or compound heterozygous IL36RN mutations showed early age onset of GPP compared to heterozygous mutations (homo vs compound hetero vs hetero = 5.5 ± 0.7 vs 13 ± 8.48 vs 25 ± 12.72). Although each case of GPP was associated with different mutation locus of IL36RN gene, all patients showed good therapeutic response to the systemic treatment with acitretin, suggesting that different types of mutations in IL36RN gene were not associated with treatment response but probably with an age of onset of GPP. Conclusion: Since GPP is a rare and severe inflammatory disease showing a strong genetic background, our present study would be useful preliminary data to understand correlation between genetic mutation status in IL36RN gene and clinical features of Korean GPP patients
Energy efficient scheduling for downlink elastic traffic in wireless networks
Lee, Jongwook,Bahk, Saewoong John Wiley Sons, Ltd. 2010 WIRELESS COMMUNICATIONS AND MOBILE COMPUTING Vol.10 No.7
<P>In wireless networks, maximizing throughput and minimizing energy consumption are two conflicting objectives. For elastic traffic, it is the total completion time, not the delay constraint of a single packet or the short-term throughput requirement, that directly affects the quality-of-service (QoS). At the same time, the energy consumption should be minimized in order to prolong the battery lifetime of the mobile station (MS). In this paper, we propose energy efficient schedulers that consider throughput and energy saving simultaneously. Through extensive simulations, we compare the proposed schemes with the conventional scheme where a mobile terminal stays awake until all the pending packets are completely serviced. The simulation results show that our schemes outperform the conventional one in terms of utility, i.e., user satisfaction, which is defined as inversely proportional to the multiplication of weighted service completion time and energy consumption. Copyright © 2009 John Wiley & Sons, Ltd.</P> <B>Graphic Abstract</B> <P>For a mobile station which is downloading elastic traffic in a wireless network, it is shown that Best-pick sleep (BPS) scheme which is proposed in this paper is effective in performance by balancing between the throughput and energy saving. <img src='wiley_img_2010/15308669-2010-10-7-WCM803-gra001.gif' alt='wiley_img_2010/15308669-2010-10-7-WCM803-gra001'> </P>
( Jongwook Oh ),( Jihee Kim ),( Young In Lee ),( Ju Hee Lee ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2
Background: Treatment of Acne scars remains a therapeutic challenge with broad range of treatment options. Especially for the atrophic scars, ablative fractional laser has demonstrated its efficacy in various reports. Meanwhile, microneedle radiofrequency (RF) can allow a more selective microthermal zone of the dermis without epidermal damage. Objectives: The aim of this study was to analyze the effect and safety of combination treatment with AFL and microneedle RF in acnes and postacne scars. Methods: The photographs of 50 patients with acnes and post-acne scars who received microneedle RF treatments were retrospectively reviewed. The reduction in numbers of active acne lesions and postacne scars, overall improvement degrees were evaluated by two dependent dermatologists, and patients’ satisfaction levels were evaluated from the patients. Results: The active acne lesions, global improvement scale and patient satisfaction levels showed significant improvement in all treated patients, although there was no significant difference in these parameters between RF alone group and combination treatment group. However, the reductions of box scars and rolling scars showed significant improvement in the combination therapy group compared to the RF alone group. Conclusion: The combination treatment with AFL and microneedle RF therapy is effective in treatment of inflammatory acne lesions and postacne scars.
Lee, Da-Hye,Lee, Jungsul,Jeon, Jongwook,Kim, Kyung-Jin,Yun, Jang-Hyuk,Jeong, Han-Seok,Lee, Eun Hui,Koh, Young Jun,Cho, Chung-Hyun Korean Society for Molecular and Cellular Biology 2018 Molecules and cells Vol.41 No.8
Angiogenesis must be precisely controlled because uncontrolled angiogenesis is involved in aggravation of disease symptoms. Vascular endothelial growth factor (VEGF)/VEGF receptor 2 (VEGFR-2) signaling is a key pathway leading to angiogenic responses in vascular endothelial cells (ECs). Therefore, targeting VEGF/VEGFR-2 signaling may be effective at modulating angiogenesis to alleviate various disease symptoms. Oleanolic acid was verified as a VEGFR-2 binding chemical from anticancer herbs with similar binding affinity as a reference drug in the Protein Data Bank (PDB) entry 3CJG of model A coordination. Oleanolic acid effectively inhibited VEGF-induced VEGFR-2 activation and angiogenesis in HUVECs without cytotoxicity. We also verified that oleanolic acid inhibits in vivo angiogenesis during the development and the course of the retinopathy of prematurity (ROP) model in the mouse retina. Taken together, our results suggest a potential therapeutic benefit of oleanolic acid for inhibiting angiogenesis in proangiogenic diseases, including retinopathy.