Human Acyl-CoA:Cholesterol Acyltransferase-inhibiting Dammarane Triterpenes from Rhus chinensis

Kim, Geum-Soog,Jeong, Tae-Sook,Kim, Young-Ock,Baek, Nam-In,Cha, Seon-Woo,Lee, Jong-Won,Song, Kyung-Sik The Korean Society for Applied Biological Chemistr 2010 Applied Biological Chemistry (Appl Biol Chem) Vol.53 No.4

In the process of screening for anti-human acyl-CoA:cholesterol acyltransferase (hACAT) agents from plant resources, we found that the 80% methanolic extract of Rhus chinensis (R. chinensis) exhibited significant antioxidative and hACAT activities in rats. Two compounds were isolated as active principles from the ethyl acetate soluble fraction of the branches of R. chinensis. The structures of compounds 1 and 2 were determined as hydroxydammarenone and semialactone, respectively, by means of MS and NMR spectroscopic analysis. Compound 1 has been isolated from this plant for the first time. Compounds 1 and 2 showed inhibitory activities on both human ACAT1 with $IC_{50}$ values of 12.4, and $79.1\;{\mu}M$ and on human ACAT2 with $IC_{50}$ values of 30.5 and $76.9\;{\mu}M$, respectively. These results suggested that R. chinensis containing dammarane triterpenes 1 and 2 might be effective in the prevention and treatment of hypercholesterolemia or atherosclerosis via inhibitory effect on hACAT.

Panax ginseng Protects Against Global Ischemia Injury in Rat Hippocampus

Kim, Young-Ock,Kim, Hak-Jae,Kim, Geum-Soog,Park, Ho-Gi,Lim, Sang-Jong,Seong, Nak-Sul,Ham, Yung-Woon,Lee, Sung-Dong,Jang, Ki-Hyo,Jung, Kyung-Hee,Chung, Joo-Ho,Kang, Soon-Ah The Korean Society of Food Science and Nutrition 2009 Journal of medicinal food Vol.12 No.1

Based on the use of Panax ginseng C.A. Meyer (Family Araliaceae) for the treatment of stroke in traditional Korean medicine, the present study was carried out to evaluate neuroprotective effects of P. ginseng after transient global cerebral ischemia using the four-vessel occlusion rat model. Nissl staining, lipid peroxidation (malondialdehyde [MDA] formation), and activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx) of rat brain were assessed. Ethanolic P. ginseng extract (200 mg/kg, i.p.) significantly protected CA1 neurons against 10 minutes of transient forebrain ischemia as demonstrated by measuring the density of neuronal cells. P. ginseng also significantly decreased the level of MDA and increased the expression of GPx and SOD. These results suggest that P. ginseng might be neuroprotective against cerebral ischemia-induced injury in rat brain by decreasing lipid peroxides and increasing the expression of GPx and SOD.

Factors affecting parental choice of childcare service for pre-school age children

Jong-soog Kim 한국여성정책연구원(구 한국여성개발원) 2013 Gender Studies and Policy Review Vol.6 No.-

The goal of this research is to identify whether women’s economic participation and types of employment affect their choice of childcare provider for pre-school aged children. Childcare options were classified into at-home care, preschool, daycare, and private educational institutions. A multinominal logit model was used to analyze the factors influencing each choice. The thirdwave data of the Korean Longitudinal Panel Survey of Women and Family (KLoWF), which includes both women’s employment variables and household childcare variables, was used. A total of 1,538 women with pre-school age children and the 543 among them who were participating in economic activities were subject to analysis. The findings of this research are as follows. While working mothers exhibited a greater propensity to use daycare facilities than did non-working mothers, when only working mothers were examined their type of employment and profession proved irrelevant to their choice between preschool and daycare. In terms of choice between daycare, at-home care, and private educational institution, excluding preschool as an option, certain professions and most employment types strongly preferred daycare. In conclusion, it is considered that while daycare-oriented policies are highly desirable in assisting working women with their childcare, the impact of both the specific type of employment and profession is negligible in working mothers’ choices between preschool and daycare. This suggests that child-related variables play a greater role in this choice than do women’s employment variables.

일반논문 : 여성취업의 빈곤완화 효과 분석

김종숙 ( Jong Soog Kim ) 한국여성경제학회 2013 여성경제연구 Vol.10 No.2

본 연구는 여성고용정책의 필요성과 타당성을 빈곤완화에서 찾기 위하여 수행되었다. 지난 10년간의 여성고용정책에도 불구하고 여성의 고용률은 정체되어 왔고, 여성고용의 질적수준은 개선되지 못하였다. 여성고용의 양적, 질적 문제점을 개선하기 위해서는 정확한 목표의 설정과 대상집단의 발굴이 중요하다. 성별 관련성을 명확하게 하기 위하여 가구단위가 아닌 개인단위의 분석을 시도해보았다. 빈곤층의 기준을 상대빈곤지표인 가구균등화소득 중위값의 60% 미만으로 설정하고 이들 가구에 속한 남녀가 취업을 통하여 얼마나 빈곤상태에서탈출하였는지를 개인단위로 분석하였다. 동시에 핵심고용연령계층인 55세 미만을 대상으로분석하였다. 한국복지패널자료를 활용하여 2단계프로빗모형을 통하여 취업의 빈곤완화효과를 추정한 결과, 남성은 취업으로 인한 빈곤탈출효과가 통계적으로 유의하게 나타나지 않은반면 여성은 취업으로 인한 탈빈곤효과가 매우 뚜렷하게 나타났다. 빈곤정책으로서 여성고용정책을 적극적으로 추진하면 빈곤완화라는 정책적 성과를 가져올 수 있으므로 저소득층여성을 대상으로 하는 적극적인 고용활성화 정책을 추진할 필요가 있다. The purpose of this study is to find the relationship between women`s employment and povery alleviation. Despite of active labor market policies on women during the last decade, women`s employment rate is still low and the quality of women`s labor condition is problematic. Increasing women`s poverty rate is another concern in Korea. The policy package of employment and welfare needs to find exact target groups in order to resolve the labor market and poverty issues of women. This study investigate the effect of employment assistance programs on poverty alleviation of women. I utilized Korea Welfare Panel study and 2 stage probit model. I targeted the people aged from 15~54 in order to show the impact of labor market policies. The result showed that women`s employment contributed to poverty alleviation significantly while men`s did not. Providing active labor market policies to women might be a very effective policy intervention both for improving women`s labor market and poverty alleviation.

경력단절 여성의 직업훈련 성과

김종숙(Kim, Jong Soog) 동국대학교 사회과학연구원 2015 사회과학연구 Vol.22 No.4

본 논문은 최근 정부의 주된 고용정책 대상인 경력단절 여성의 직업훈련 성과를 측정하는 것이 주된 목적이다. 직업훈련의 취업과 임금효과를 분석한 선행연구들은 성별을 고려하고 있지만 경력단절 여성의 특성을 반영하는데 자료의 한계가 있었다. 전국의 여성을 대상으로 조사하여 경력단절 여성의 특성을 반영한 대표성 있는 자료인 2013년 ‘경력단절여성 등 경제활동실태조사’ 를 이용하여 회귀분석 및 성향점수매칭법 등을 분석한 결과, 경력을 단절한 여성들에게 직업훈련은 취업하는데 긍정적 영향을 미치지만 노동시장 성과인 임금에는 영향을 미치지 못했다. 경력단절 여성들이 재취업이후 상당수 재 경력단절을 경험한다는 사실을 고려할 때 직업훈련이 보다 근본적이고 장기적인 재취업기반이 되도록 개선될 필요가 있음을 보여주는 결과라 하겠다. The purpose of this study is to evaluate the labor market outcome of government policy for “career disrupted women’. Vocational training, as one of the active labor market policies, aims to increase the chance of getting jobs and to enhance labor market condition via increasing skills and productivity. This study utilized ”Survey of Career Disrupted Women in 2013“ collected by Ministry of gender equality and National statistics office. Results showed that vocational training increased the probability of getting jobs, but did not positively influence wage level of workers. Regarding that career disrupted women tend to be re-career disrupted after they come back to labor market, policies need to be improved with long term perspectives.

Human Acyl-CoACholesterol Acyltransferase-inhibiting Dammarane Triterpenes from Rhus chinensis

( Geum Soog Kim ),( Tae Sook Jeong ),( Young Ock Kim ),( Nam In Baek ),( Seon Woo Cha ),( Jong Won Lee ),( Kyung Sik Song ) 한국응용생명화학회 2010 Applied Biological Chemistry (Appl Biol Chem) Vol.53 No.4

In the process of screening for anti-human acyl-CoA:cholesterol acyltransferase (hACAT) agents from plant resources, we found that the 80% methanolic extract of Rhus chinensis (R. chinensis) exhibited significant antioxidative and hACAT activities in rats. Two compounds were isolated as active principles from the ethyl acetate soluble fraction of the branches of R. chinensis. The structures of compounds 1 and 2 were determined as hydroxydammarenone and semialactone, respectively, by means of MS and NMR spectroscopic analysis. Compound 1 has been isolated from this plant for the first time. Compounds 1 and 2 showed inhibitory activities on both human ACAT1 with IC50 values of 12.4, and 79.1 μM and on human ACAT2 with IC(50) values of 30.5 and 76.9 μM, respectively. These results suggested that R. chinensis containing dammarane triterpenes 1 and 2 might be effective in the prevention and treatment of hypercholesterolemia or atherosclerosis via inhibitory effect on hACAT.

Bioactive Materials ; Human Acyl-CoA:Cholesterol Acyltransferase-inhibiting Dammarane Triterpenes from Rhus chinensis

Geum Soog Kim,Tae Sook Jeong,Young Ock Kim,Nam In Baek,Seon Woo Cha,Jong Won Lee,Kyung Sik Song 한국응용생명화학회 2010 Journal of Applied Biological Chemistry (J. Appl. Vol.53 No.4

In the process of screening for anti-human acyl-CoA:cholesterol acyltransferase (hACAT) agents from plant resources, we found that the 80% methanolic extract of Rhus chinensis (R. chinensis) exhibited significant antioxidative and hACAT activities in rats.

정책논문 : 여성취업자의 국민연금 가입률과 영향요인

김종숙 ( Jong Soog Kim ) 한국여성경제학회 2011 여성경제연구 Vol.8 No.1

노후소득보장에 대한 중요성이 강조되면서 국민연금 가입은 중요한 노후소득보장 수단이 되고 있다. 여성들은 기대수명이 길고 상대적으로 노후 빈곤화에 취약하기 때문에 공적 노후보장이 더욱 필요한 집단으로 인식된다. 그럼에도 불구하고 여전히 여성들의 국민연금 가입비중은 남성에 비하여 매우 낮은 수준이며 특히 경제활동을 기반으로 하고 있는 국민연금 제도에서 여성취업자의 가입률이 매우 저조하다. 본 고에서는 여성취업자의 국민연금 가입률과 이에 영향을 미치는 제 요인들을 살펴봄으로써 향후 여성취업자의 국민연금 본인가입을 제고할 수 있는 시사점을 도출하고자 하였다. 제2차 여성가족패널조사를 분석한 결과, 여성다수 업종인 음식 및 숙박업이나 교육서비스업, 개인서비스업이나 가구내 고용에 종사하는 여성들의 국민연금 가입 가능성이 유의하게 낮았고, 비정규직 등 고용지위나 영세사업장 고용여부가 유의한 영향을 미쳤다. 직종에서는 농림어업분야 종사자의 국민연금가입 가능성이 유의하게 낮았다. 따라서 여성 취업자의 국민연금 가입을 유인하기 위하여 해당하는 업종과 직종을 중심으로 다양한 가입경로를 모색할 필요가 있으며 현재 국민연금 가입구조에 대한 보다 구체적인 검토가 필요할 것이다. National Pension is the most important method to protect old-age income security. Since women`s life expectancy is longer than men`s, and the poverty rate of women is higher than men`s, women need to be protected by public pension. Women`s rate of planholder is much lower despite the fact that women need more income security. Of particular interest is women workers` lower rate of planholder under the National Pension system, designed by economic activities. This study explores the rate of National Pension Holder and factors affecting the rate among women workers. Klowf(Korea Longitudinal study of Women and Family) was utilized to analyze the factors. The results show that particular industries and occupations which are women dominant have significantly lower planholder rates. Women workers with lower labor market status such as irregular worker and part-time workers demonstrate lower rate of planholder. Therefore the National Pension system needs to be modified in order to cover all workers regardless labor market status.

一部 農村老人의 餘暇活動과 生活滿足度와의 關聯性

김재숙(Jae-Soog Kim),박종(Jong Park),류소연(So-Yeon Ryu),이철갑(Chul-Gab Lee),김학렬(Hak-Ryul Kim),김양옥(Yang-Ok Kim) 한국농촌의학 지역보건학회 1999 농촌의학·지역보건 Vol.24 No.1

Separation Technology , Thermodynamics : Adsorptive Ethylene Recovery from LDPE Off - Gas

(Soog Haeng Cho),(Sang Sup Han),(Jong Nam Kim),(Jong Ho Park),(Hyun Ku Rhee) 한국화학공학회 2002 Korean Journal of Chemical Engineering Vol.19 No.5