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        Cottonseed biodiesel oxidative stability in mixture with natural antioxidants

        João Paulo Almeida Freitas,Fernanda Rocha Morais França,Maria Susana Silva,Richard James Toms,Gabriel Francisco da Silva 한국화학공학회 2019 Korean Journal of Chemical Engineering Vol.36 No.8

        We evaluated the antioxidant power of the natural extracts catechin, curcumin and quercetin on the oxidative stability of methylic cottonseed oil biodiesel by applying the simplex-centroid augmented mixture experimental design, in addition to verifying the existence and the type of synergy among the extracts. The oxidative stability was measured using Rancimat method (EN 14112) for biodiesel added with 1,000, 2,000 and 3,000 ppm of additives, and compared with the commercial synthetic antioxidant butyl hydroxyanisole at the same concentrations. All additives had a positive effect on biodiesel oxidative stability; in addition, catechin and quercetin proved to be more efficient than the synthetic antioxidant, whereas curcumin showed similar results. The results also revealed that the interactions among the extracts varied not only with the proportion in which they were added to the biodiesel, but also with the total concentration, so that the increase in concentration reduced the magnitude of the synergistic effect.

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        Antinociceptive Action and Redox Properties of Citronellal, an Essential Oil Present in Lemongrass

        Lucindo Quintans-Júnior,Ricardo Fagundes da Rocha,Fernanda Freitas Caregnato,José Claudio Fonseca Moreira,Francilene Amaral da Silva,Adriano Antunes de Souza Araújo,João Paulo Almeida dos Santos,Mônic 한국식품영양과학회 2011 Journal of medicinal food Vol.14 No.6

        Citronellal (CT) is a monoterpenoid and the major constituent of the mixture of terpenoids that give the citronella oil its lemon scent. Citronella oil is widely used around the world for various purposes and is mainly obtained from plants of the Cymbopogon genus, which are known as “lemongrass.” Considering these plants have been used worldwide for various medicinal purposes, the interest of researchers to understand the biological activities of monoterpenoids related to the Cymbopogon genus has been increasing. In the present work, we investigated the antinociceptive action and the redox properties of CT. Our results indicate that intraperitoneal injection of CT was effective in reducing nociceptive face-rubbing behavior in both phases of the formalin test, which was also naloxone-sensitive. CT also evoked antinociceptive response in the capsaicin and glutamate tests. The total radical-trapping antioxidant parameter and total antioxidant reactivity assays indicate that CT at doses of 0.1 and 1 mg/mL exerts a significant antioxidant activity, which is probably related to its ability to scavenge superoxide and nitric oxide, but not H_2O_2 or hydroxyl radicals, as evaluated separately by specific in vitro tests. These results show for the first time the antinociceptive potential of CT and indicate that the antioxidant properties of this compound may rely on its mechanism of biological actions because CT-containing natural products are used to treat various diseases related to oxidative stress and reactive species.

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