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        A numerical procedure for reinforced concrete columns with a focus on stability analysis

        Susana L. Pires,Maria Cecilia A.T. Silva 사단법인 한국계산역학회 2014 Computers and Concrete, An International Journal Vol.14 No.6

        The purpose of this paper is to present a numerical procedure to analyse reinforced concrete columns subjected to combined axial loads and bending that rigorously considers nonlinear material and nonlinear geometric characteristics. Column design and stability analysis are simultaneously regarded. A finite element method is used for calculating displacements and the material and geometric nonlinearities are taken into account using an iterative process. A computer program is developed from the proposed numerical procedure, and the efficiency of the program is verified against available experimental data. The model applies to constant rectangular cross sectional columns with symmetric reinforcement distribution.

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        Cottonseed biodiesel oxidative stability in mixture with natural antioxidants

        João Paulo Almeida Freitas,Fernanda Rocha Morais França,Maria Susana Silva,Richard James Toms,Gabriel Francisco da Silva 한국화학공학회 2019 Korean Journal of Chemical Engineering Vol.36 No.8

        We evaluated the antioxidant power of the natural extracts catechin, curcumin and quercetin on the oxidative stability of methylic cottonseed oil biodiesel by applying the simplex-centroid augmented mixture experimental design, in addition to verifying the existence and the type of synergy among the extracts. The oxidative stability was measured using Rancimat method (EN 14112) for biodiesel added with 1,000, 2,000 and 3,000 ppm of additives, and compared with the commercial synthetic antioxidant butyl hydroxyanisole at the same concentrations. All additives had a positive effect on biodiesel oxidative stability; in addition, catechin and quercetin proved to be more efficient than the synthetic antioxidant, whereas curcumin showed similar results. The results also revealed that the interactions among the extracts varied not only with the proportion in which they were added to the biodiesel, but also with the total concentration, so that the increase in concentration reduced the magnitude of the synergistic effect.

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        The Ketone Bridge Between the Heart and the Bladder: How Fast Should We Go?

        Gabriel Faria-Costa,João Oliveira,Inês Vilas-Boas,Inês Campelo,Elisa Azeredo Silva,Carmen Brás-Silva,Susana Maria Silva,Tiago Antunes-Lopes,Ana Charrua 대한배뇨장애요실금학회 2024 International Neurourology Journal Vol.28 No.-

        Metabolic syndrome (MS) is associated with both cardiovascular and bladder dysfunction. Insulin resistance (IR) and central obesity, in particular, are the main risk factors. In these patients, vicious pathological cycles exacerbate abnormal carbohydrate metabolism and sustain an inflammatory state, with serious implications for both the heart and bladder. Ketone bodies serve as an alternative energy source in this context. They are considered a “super-fuel” because they generate adenosine triphosphate with less oxygen consumption per molecule, thus enhancing metabolic efficiency. Ketone bodies have a positive impact on all components of MS. They aid in weight loss and glycemic control, lower blood pressure, improve lipid profiles, and enhance endothelial function. Additionally, they possess direct anti-inflammatory, antioxidant, and vasodilatory properties. A shared key player in dysfunction of both the heart and bladder dysfunction is the formation of the NLRP3 inflammasome, which ketone bodies inhibit. Interventions that elevate ketone body levels—such as fasting, a ketogenic diet, ketone supplements, and sodium-glucose cotransporter 2 inhibitors—have been shown to directly affect cardiovascular outcomes and improve lower urinary tract symptoms derived from MS. This review explores the pathophysiological basis of the benefits of ketone bodies in cardiac and bladder dysfunction.

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