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- 저자 : Jiu-Liang Zhang (검색결과 4 건)
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Ultra-low cycle fatigue tests of Class 1 H-shaped steel beams under cyclic pure bending
Xianzhong Zhao,Yafeng Tian,Liang-Jiu Jia,Tao Zhang 국제구조공학회 2018 Steel and Composite Structures, An International J Vol.26 No.4
This paper presents experimental and numerical study on buckling behaviors and hysteretic performance of Class 1 H-shaped steel beam subjected to cyclic pure bending within the scope of ultra-low cycle fatigue (ULCF). A loading device was designed to achieve the pure bending loading condition and 4 H-shaped specimens with a small width-to-thickness ratio were tested under 4 different loading histories. The emphasis of this work is on the impacts induced by local buckling and subsequent ductile fracture. The experimental and numerical results indicate that the specimen failure is mainly induced by elasto-plastic local buckling, and is closely correlated with the plastic straining history. Compared with monotonic loading, the elasto-plastic local buckling can occur at a much smaller displacement amplitude due to a number of preceding plastic reversals with relative small strain amplitudes, which is mainly correlated with decreasing tangent modulus of the material under cyclic straining. Ductile fracture is found to be a secondary factor leading to deterioration of the load-carrying capacity. In addition, a new ULCF life evaluation method is proposed for the specimens using the concept of energy decomposition, where the cumulative plastic energy is classified into two categories as isotropic hardening and kinematic hardening correlated. A linear correlation between the two energies is found and formulated, which compares well with the experimental results.
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Online Monitoring System of Fish Behavior
Gang Xiao,Wen Zhang,Yong-Liang Zhang,Jiu-Jun Chen,Shan-Shan Huang,Lu-Ming Zhu 제어로봇시스템학회 2011 제어로봇시스템학회 국제학술대회 논문집 Vol.2011 No.10
In order to overcome the defect of physic-chemical monitoring system and enhance the intelligence of biological monitoring technology, an online monitoring system of fish behavior is proposed in this paper. The main contributions of this system are as follows: 1) adaptive background updating algorithm (ABU); 2) automatic camshift tracking algorithm (ACT) with twice searching; 3) particle filter tracking (PFT) algorithm; 4) persistent turning walker (PTW) model; 5) artificial immune algorithm (AIA). This online system is used to monitor and analyse the fish behavior continuously, establish a normal behavior model and detect the anormal behavior. Experimental results show that the system is running stably and has achieved well effect in the simulation environment.
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Corn Peptides Protect Against Thioacetamide-Induced Hepatic Fibrosis in Rats
Jie Lv,Zhi-Kui Nie,Jiu-Liang Zhang,Feng-Yan Liu,Zhenzhen Wang,Zhi-Li Ma,Hui He 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.10
Certain bioactive peptides are reported to be able to alleviate hepatic fibrosis. Our previous work has confirmed the hepatoprotective effect of corn peptides (CPs) that are prepared from a high protein by-product, corn gluten meal, on acute liver injury in an animal model. However, the antifibrotic activity of CPs remained to be elucidated. In this study, the hepatoprotective effect of CPs on thioacetamide (TAA)-induced liver fibrosis was tested. Results showed that CPs (100 mg/kg body weight) significantly decreased the levels of alanine transaminase/aspartate transaminase, laminin, type IV collagen, and type III collagen in serum and increased the serum albumin levels and total antioxidant capacity. Additionally, with CP treatment (100 mg/kg body weight), a significant decrease was observed in the levels of malondialdehyde, nitric oxide, hydroxyproline, transforming growth factor b1, and lactate dehydrogenase activity as well as the liver index, while the activity of superoxidedismutase was significantly increased in livers. The histological and morphological analysis showed that the hepatocyte structure in CP-treated rats was superior to that of TAA-injured rats, and inflammation and fibrosis were also ameliorated. Therefore, CPs can be used as an option for prevention and adjuvant therapy of liver fibrosis.
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Dong Zhao,Ming-Yao Gu,Jiu Liang Xu,Li Jun Zhang,Shi Yong Ryu,양현옥 한국응용약물학회 2019 Biomolecules & Therapeutics(구 응용약물학회지) Vol.27 No.1
Ginger, one of worldwide consumed dietary spice, is not only famous as food supplements, but also believed to exert a variety of remarkable pharmacological activity as herbal remedies. In this study, a ginger constituent, 12-dehydrogingerdione (DHGD) was proven that has comparable anti-inflammatory activity with positive control 6-shogaol in inhibiting LPS-induced interleukin (IL)-6, tumor necrosis factor (TNF)-α, prostaglandin (PG) E2, nitric oxide (NO), inducible NO synthase (iNOS) and cyclooxygenase (COX)-2, without interfering with COX-1 in cultured microglial cells. Subsequent mechanistic studies indicate that 12-DHGD may inhibit neuro-inflammation through suppressing the LPS-activated Akt/IKK/NF-κB pathway. Furthermore, 12-DHGD markedly promoted the activation of NF-E2-related factor (Nrf)-2 and heme oxygenase (HO)-1, and we demonstrated that the involvement of HO-1 on the production of pro-inflammatory mediators such as NO and TNF-α by using a HO-1 inhibitor, Zinc protoporphyrin (Znpp). These results indicate that 12-DHGD may protect against neuro-inflammation by inhibiting Akt/IKK/IκB/NF-κB pathway and promoting Nrf-2/HO-1 pathway.
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