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카메라 옵스큐라를 이용한 미술 교과용 A-STEAM 수업자료 개발
이민정(Lee, Min Jung) 조예현(Jo, Ye Hyun) 김진수(Kim, Jinsoo) 한국미술교육학회 2014 美術敎育論叢 Vol.28 No.1
The purpose of this study is to develop an A-STEAM program using the Camera Obscura. The starting point of this study is the problems which students can encounter in real-life and it is designed to enable students to establish a research project. to integrate science, technology, engineering, and mathematics with main focus being art, and to explore all the avenues of expression using the Camera Obscura. In doing so, this study proposes possibilities of enhancement of students abilities to solve the problems and the development of artistic sensibilities. The process of developing the A-STEAM Program for art as a subject follows the PDIE process model by Jinsoo Kim. This study leaves the practice and evaluation as follow-up research and develops the teaching-learning process agenda, the paper for students' activities. and the materials for teachers' guidance by reflecting on the aspects of circumstantiation, creative design, and emotional touch. 본 논문의 목적은 카메라 옵스큐라를 이용한 미술중심 융합인재교육을 위한 수업자료의 개발에 있다. 이를 위하여 본 연구는 초둥학교 5, 6학년의 미술교과서 '관찰 표현' 단원을 재구성하고 학생자신이 실제 상황에서 부딪힐 수 있는 문제를 출발점으로 삼아 학생 스스로 과제를 설정하도록 하였다. 또한 카메라 옵스큐라를 이용한 표현 및 탐구 활동을 통해 미술 중심의 과학, 기술, 공학, 수학의 연계를 시도하였으며 시행착오를 거치는 가운데 탐구 활동을 통하여 학습자의 창의적 문제해결력과 예술적 감수성 발달의 가능성을 제시하였다. 수업자료 개발 과정은 김진수 (2012)의 초ㆍ중둥학교 STEAM 교육 수업자료 개발을 위한 PDIE 절차 모형을 따라 미술 교과용 A-STEAM 수업자료를 개발하였으며, 실행과 평가 단계는 후속 연구로 계획하고 각 차시별로 STEAM 학습 준거인 상황 제시, 창의적 설계, 감성적 체험의 요소를 반영하여 교수ㆍ학습 과정안과 학생 활동지, 교사용 자료를 개발하였다.
Clinical Characteristics of Patients with Smear-negative Pulmonary Tuberculosis
( Seung Hoon Kim ),( Ju Sang Kim ),( Hyung Woo Kim ),( Yong Hyun Kim ),( Sung Soo Jeong ),( Jee Youn Oh ),( Jin Woo Kim ),( Sang Haak Lee ),( Sung Kyoung Kim ),( Sun-hyung Kim ),( Jinsoo Min ) 대한결핵 및 호흡기학회 2023 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.136 No.0
초고속 원심방사에 의한 아세트산프로피온산 셀룰로오스/폴리부틸렌 숙시네이트 다공성 마이크론 섬유 제조
김태영(Tae Young Kim),김미경(Mi Kyung Kim),김진수(Jinsoo Kim),이정언(Jungeon Lee),정재훈(Jae Hoon Jung),김영권(Youngkwon Kim),김태현(Tae Hyeon Kim),김기영(Ki Young Kim),염정현(Jeong Hyun Yeum) 한국염색가공학회 2023 韓國染色加工學會誌 Vol.35 No.4
Cellulose is an abundant biodegradable material in nature with excellent properties, but due to its poor processability, it has been widely studied for processing through modification. Cellulose acetate propionate (CAP) is a cellulose derivative in which the hydroxyl group of cellulose is replaced by acetyl and propionyl groups. CAP has several advantages, such as excellent solubility, structural stability, light and weather resistance, and good transparency. Porous nanofibers with excellent specific surface area, which can be applied in various fields, can be easily formed by the phase separation method using highly volatile solvents. High speed centrifugal spinning is a nano/micro fiber preparation method with advantages such as fast spinning and easy alignment control. In this study, a CAP/polybutylene succinate (PBS) spinning solution with chloroform as solvent was prepared to prepare porous microfibers and the fiber morphology was examined as a function of the disk rotation speed in an high speed centrifugal spinning device.
Kim, Haegyeom,Kim, Hyungsub,Kim, Sung-Wook,Park, Kyu-Young,Kim, Jinsoo,Jeon, Seokwoo,Kang, Kisuk Elsevier 2012 Carbon Vol.50 No.5
<P><B>Abstract</B></P><P>LiFePO<SUB>4</SUB> nanoparticles were grown on nano-graphite platelet (NGP) using a simple chemical route. The material was used as the cathode in Li-ion rechargeable batteries and exhibited excellent cyclability and rate capability because of the easy electron transport in it. The electrochemical stability of the electrode was improved by the two-dimensional conductive network of the NGP. The resulting electrodes delivered a specific capacity of about 150mAhg<SUP>−1</SUP> at a current rate of 135mAg<SUP>−1</SUP> (∼0.8C) after 100 cycles with no capacity fade. At elevated current rates, the electrodes exhibited capacities of more than 100mAhg<SUP>−1</SUP> at a current density of 2000mAg<SUP>−1</SUP> (∼12C) without further incorporation of conductivity agents or coatings.</P>
Kim Mi-Yeon,Kim Mi Jeong,Lee Changyeob,Lee Juwon,Kim Sang Seong,Hong Sungho,Kim Hyoung Tae,Seo Jinsoo,Yoon Ki-Jun,Han Sungho 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Enhancing adult neurogenesis in the brain has been suggested as a potential therapeutic strategy for AD. We developed a screening platform, ATRIVIEW®, for molecules that activate neuronal differentiation of adult mouse NSCs. The most potent hit from an FDA-approved drug library was SNR1611 (trametinib), a selective MEK1/2 inhibitor. We found that trametinib increases the levels of P15INK4b and Neurog2, suggesting a mechanism by which MEK1/2 inhibition induces neuronal differentiation. Oral administration of trametinib increased adult neurogenesis in the dentate gyrus and subventricular zone of the 5XFAD AD mouse model. Surprisingly, we also found that trametinib enhanced adult neurogenesis in the cortex. Consequently, trametinib rescued AD pathologies such as neuronal loss and cognitive impairment in 5XFAD mice. Finally, trametinib induced neurogenic differentiation of NSCs derived from AD patient iPSCs, which suggests its potential therapeutic application. Altogether, we suggest that restoration of endogenous adult neurogenesis by trametinib may be a promising therapeutic approach to AD.
Role of Fluoroquniolone in Isoniazid-monoresistant Tuberculosis : A Multicenter Study in Korea
( Jinsoo Min ),( Ju Sang Kim ),( Hyung Woo Kim ),( Ji Young Kang ),( Sung Kyoung Kim ),( Jin Woo Kim ),( Yong Hyun Kim ),( Sang Haak Lee ),( Hyoung Kyu Yoon ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-
Background In 2018, the World Health Organization (WHO) guidelines for the treatment of isoniazid (H)-monoresistant (Hr) tuberculosis (TB) recommend a six-month four-drug regimen: rifampicin (R), ethambutol (E), pyrazinamide (Z) and levofloxacin. However, the WHO assessed its regimen to be of very low certainty. This cohort study assessed the impact of fluoroquinolone (Fq) on treatment of effectiveness among Hr-TB patients. Methods This was a retrospective cohort study of 356 Hr-TB patients in 2010-2018. Baseline regimens were classified into 2 groups based on the duration of Z uses; 6-month REZ (6REZ) and combination of 2-month REZ and 7-month RE (2REZ/7RE). Multivariable logistic regression was performed to assess association between Fq use and negative regimen-specific outcomes, which included death due to TB, treatment failure or disease recurrence. Results Of 365 enrolled patients, 256 (71.9%) were treated with 6REZ regimen and 116 (32.6%) with additional Fq use. There were 93 (38.8%) and 39 (33.6%) cases of negative regimen-specific outcomes in patients treated without and with Fq uses, respectively. In a univariable logistic regression model comparing with and without Fq uses, there was no difference in odds of negative regimen-specific outcomes (odds ratio [OR] = 0.80, 95% confidence interval [CI] = 0.50-1.27); however, compared to 2REZ/7RE regimen, 6REZ regimen was significantly associated with negative regimen-specific outcomes (OR = 2.15, 95% CI = 1.29-3.61). Results varied minimally in a multivariable model. Among patients with positive outcomes, the median overall treatment period was 274 days and additional Fq use did not reduce overall treatment period (273 days in regimen without Fq vs. 279 days in regimen with Fq, p=0.086). Conclusions We found that additional Fq use did not show more benefits for Hr-TB patients. However, 2REZ/7RE regimen was more efficacious than 6REZ regimen. The WHO’s Hr-TB recommendation needs to be carefully re-evaluated with further prospective studies.
Kim, Myoung-Hwan,Choi, Jeonghoon,Yang, Jinhee,Chung, Woosuk,Kim, Ji-Hyun,Paik, Sang Kyoo,Kim, Karam,Han, Seungnam,Won, Hyejung,Bae, Young-Soo,Cho, Suk-Hee,Seo, Jinsoo,Bae, Yong Chul,Choi, Se-Young,Kim The Society 2009 The Journal of neuroscience Vol.29 No.5
<P>IRSp53 is an adaptor protein that acts downstream of Rac and Cdc42 small GTPases and is implicated in the regulation of membrane deformation and actin filament assembly. In neurons, IRSp53 is an abundant postsynaptic protein and regulates actin-rich dendritic spines; however, its in vivo functions have not been explored. We characterized transgenic mice deficient of IRSp53 expression. Unexpectedly, IRSp53(-/-) neurons do not show significant changes in the density and ultrastructural morphologies of dendritic spines. Instead, IRSp53(-/-) neurons exhibit reduced AMPA/NMDA ratio of excitatory synaptic transmission and a selective increase in NMDA but not AMPA receptor-mediated transmission. IRSp53(-/-) hippocampal slices show a markedly enhanced long-term potentiation (LTP) with no changes in long-term depression. LTP-inducing theta burst stimulation enhances NMDA receptor-mediated transmission. Spatial learning and novel object recognition are impaired in IRSp53(-/-) mice. These results suggest that IRSp53 is involved in the regulation of NMDA receptor-mediated excitatory synaptic transmission, LTP, and learning and memory behaviors.</P>
뇌파 기반 Mental Workload 지표와 N-back 과제 수행 능력 간의 상관관계 연구
Jinsoo Kim,Miyoung Kim,Eunmi Oh,Sung-Phil Kim 대한인간공학회 2013 대한인간공학회 학술대회논문집 Vol.2013 No.10
Objective: This study aims to investigate a relationship between a neural correlate of mental workload and the performance of the N-back memory task. Background: Many studies have explored neuronal correlates of mental workload by measuring the brain signal. In particular, the power of the theta rhythm (4-8 Hz) embedded in electroencephalogram (EEG) over the frontal region of the human brain has been shown to vary with mental workload. Studies have shown correlations between the frontal theta power and mental workload via various mental tasks, including the N-back task, Sternberg’s task, the multi-attribute task battery, mental arithmetic tasks and driving tasks, to name a few. However, behavioral evidence regarding the correlation between frontal theta power in individuals and their behavioral mental task performances still remains unclear. Method: Ten healthy subjects performed the N-back task with various task difficulties (0-3 back tasks), while their EEG signals were recorded using a 20-channel system. The power spectrum of the theta band (4-8 Hz) from bandpass-filtered EEG signals at the frontal channel (Fz) was calculated for each task. Results: The frontal theta power exhibited significant positive linear correlations with the error rates both in the 2-back and 3-back tasks (r > 0.68, F-test, p < 0.05), but neither in the 0-back task nor in the 1-back task. Conclusion: Individuals with poor N-back task performance showed greater frontal theta power, reflecting heavier mental workloads than those with good performance. The results indicate that one may use the frontal theta power of EEG to index individuals’ mental capacity in performing a given task.