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Improving Hotel Performance Using Relationship Marketing
Han, Jinsoo,vKim. Woogon 한국호텔경영학회 ( 구 한국호텔외식경영학회 ) 1999 Korean Journal of Hotel Administration Vol.1 No.1
This study investigated the relation between relationship antecedents and relationship quality as well as the relation between relationship quality and relationship consequences. This study will help hotel managers to design a guideline to build efficient relationship marketing strategies in the Korean hotel industry. Effective usage of relationship marketing strategies will be able to increase repeat guest and more positive word-of-mouth. To analyze data collected from 27 luxury hotels in Seoul, LISREL(Linear Structural Relationship) model was utilized to construct the cause-effect model of relationship marketing between hotel and guest. The empirical results of this study are twofold: the higher the antecedents such as confidence and communication service, the higher relationship quality is; the higher relationship quality is, the higher guest commitment is and the higher repeat purchase and word-of-mouth.
Regulated RalBP1 Binding to RalA and PSD-95 Controls AMPA Receptor Endocytosis and LTD
Han, Kihoon,Kim, Myoung-Hwan,Seeburg, Daniel,Seo, Jinsoo,Verpelli, Chiara,Han, Seungnam,Chung, Hye Sun,Ko, Jaewon,Lee, Hyun Woo,Kim, Karam,Heo, Won Do,Meyer, Tobias,Kim, Hyun,Sala, Carlo,Choi, Se-Youn Public Library of Science 2009 PLoS biology Vol.7 No.9
<▼1><P>A two step mechanism was identified that regulates receptor endocytosis during the development of long-term depression (LTD), a long-lasting decrease in synaptic transmission.</P></▼1><▼2><P>Long-term depression (LTD) is a long-lasting activity-dependent decrease in synaptic strength. NMDA receptor (NMDAR)–dependent LTD, an extensively studied form of LTD, involves the endocytosis of AMPA receptors (AMPARs) via protein dephosphorylation, but the underlying mechanism has remained unclear. We show here that a regulated interaction of the endocytic adaptor RalBP1 with two synaptic proteins, the small GTPase RalA and the postsynaptic scaffolding protein PSD-95, controls NMDAR-dependent AMPAR endocytosis during LTD. NMDAR activation stimulates RalA, which binds and translocates widespread RalBP1 to synapses. In addition, NMDAR activation dephosphorylates RalBP1, promoting the interaction of RalBP1 with PSD-95. These two regulated interactions are required for NMDAR-dependent AMPAR endocytosis and LTD and are sufficient to induce AMPAR endocytosis in the absence of NMDAR activation. RalA in the basal state, however, maintains surface AMPARs. We propose that NMDAR activation brings RalBP1 close to PSD-95 to promote the interaction of RalBP1-associated endocytic proteins with PSD-95-associated AMPARs. This suggests that scaffolding proteins at specialized cellular junctions can switch their function from maintenance to endocytosis of interacting membrane proteins in a regulated manner.</P></▼2><▼3><P><B>Author Summary</B></P><P>Neurons adapt over time in order to dampen their response to prolonged or particularly strong stimuli. This process, termed long-term depression (LTD), results in a long-lasting decrease in the efficiency of synaptic transmission. One extensively studied form of LTD requires the activation of a specific class of receptors known as NMDA glutamate receptors (NMDARs). A key molecular event initiated by NMDA receptor activation is the stimulation of protein phosphatases. Another key event is internalization via endocytosis of synaptic AMPA glutamate receptors (AMPARs). However, the mechanism by which protein dephosphorylation is coupled to AMPAR endocytosis has remained unclear. Here, we help to define this mechanism. We show that endocytic proteins, including RalBP1, are widely distributed in neurons under normal conditions. Upon NMDAR activation, the small GTPase RalA becomes activated and binds to RalBP1, resulting in the translocation of RalBP1 and RalBP1-associated endocytic proteins to synapses. At the same time, RalBP1 becomes dephosphorylated, which promotes its binding to the postsynaptic scaffold protein PSD-95, a protein that itself associates with AMPARs. This concerted recruitment of endocytic proteins to the vicinity of AMPARs results in AMPAR endocytosis. On the basis of our data, we propose a model in which dual binding of RalBP1 to both RalA and PSD-95 following RalBP1 dephosphorylation is essential for NMDAR-dependent AMPAR endocytosis during LTD.</P></▼3>
Jinsoo Han,Chang-Sic Choi,Ilwoo Lee IEEE 2011 IEEE transactions on consumer electronics Vol.57 No.1
<P>This paper describes more efficient home energy management system to reduce power consumption in home area. We consider the room easily controllable with an IR remote control of a home device. The room has automatic standby power cut-off outlets, a light, and a ZigBee hub. The ZigBee hub has an IR code learning function and educates the IR remote control signal of a home device connected to the power outlet. Then the power outlets and the light in the room can be controlled with an IR remote control. A typical automatic standby power cut-off outlet has a waiting time before cutting off the electric power. It consumes standby power during that time. To eliminate the waiting time, we turn off the home device and the power outlet simultaneously with an IR remote control through the ZigBee hub. This method actively reduces the standby power. The proposed HEMS provides easy way to add, delete, and move home devices to other power outlets. When a home device is moved to the different outlet, the energy information of the home device is kept consistently and seamlessly regardless of location change. The proposed architecture gives more efficient energy-saving HEMS.</P>
한진수 ( Jinsoo Han ),김태영 ( Taeyoung Kim ) 한국교원대학교 과학교육연구소 2016 청람과학교육연구논총 Vol.22 No.2
최근 세계적으로 STEAM 교육이 관심을 끌고 있는 이유는 그것이 학습자의 문제해결 능력과 관련이 있기 때문이라고 할 수있다. 현대 사회에서 하나의 문제는 많은 법교과적인 요소를 함유하고 있다. 예를 들어 경제적인 현상은 인간 심리학, 수학적분석, 공공 정책학, 과학기술 등과 연관이 있다. 따라서, 본 연구의 목적은 초등학교정보기기 수업에서 STEAM 교육을 설계하는데 있다. 이 목적을 위하여 연구자들은 학생들의 학습동기와 성취도를 향상시키기 위하여 적절한 STEAM 수업자료를 개발하였고, 그 자료를 실제 수업에 적용하였다. 우리가 개발한 STEAM 교육 수업이 학생들의 정보기기에 대한 이해와 문제해결 역량을 향상시키기를 기대하여 본다. In these days, the STEAM-based education attracts attention of educational institutions worldwide, since it is related to the leaners` problem-solving ability. In modern society, a problem contains interdisciplinary elements. For example, an economic symptom has the subproblem of human psychology, mathematical analysis, public policy, science and technology and so on. Thus, the purpose of this study is to design of a STEAM-based class on computer devices for elementary school students. For this goal, we developed an appropriate STEAM-based teaching-learning course that can improve the students` learning motivation and achievement, and we applied our teaching-learning materials to the elementary school students. We hope that our elementary STEAM-based class on computer device is helpful for increasing students` comprehension on computer devices learning, and further it increases students` problem solving ability.
Kim, Sung Han,Seo, Seong Il,Lee, Hyun Moo,Choi, Han-Yong,Jeon, Seung Hyun,Lee, Hyung-Lae,Kwon, Tae Gyun,Kim, Yong-June,Kim, Wun-Jae,Chung, Jinsoo The Korean Academy of Medical Sciences 2016 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.31 No.12
<P>This study aimed to evaluate the efficacy, safety, and tolerability of 2-cycled neoadjuvant sunitinib therapy (NST) in patients with inoperable metastatic renal cell carcinoma (mRCC). Between 2009 and 2012, 14 patients with inoperable mRCC from 5 Korean academic centers were prospectively enrolled after collecting their clinicopathological data and completing health-related questionnaires. The best overall response (BOR), safety profile, and changes in quality of life during NST were assessed using the RECIST criteria (version 1.0), CTCAE criteria (version 4.0), and the Cancer Quality of Life Questionnaire (QLQ-C30). Among the 14 patients, 9 patients (64.3%) experienced partial response or stable disease state, and 5 patients (35.7%) did not complete treatment, with 1 case of disease progression (7.1%), 3 grade 3 adverse events (21.4%), and 1 voluntary withdrawal (7.1%). Four patients (28.6%) were successfully converted to an operable state and underwent surgery after NST. The BOR for the primary renal lesions was 22.2%, with a median 1.3-cm diameter reduction (range: 0–2.8 cm) from a baseline diameter of 10.3 cm (range: 6.6–15.8 cm). The other 18 measurable metastatic lesions exhibited a BOR of 55.6%. The QLQ-C30 questionnaire results revealed significant improvements in the quality of life domain, although we observed significant increases in the scores for fatigue, nausea and vomiting, and the financial effects of NST (<I>P</I> < 0.05). Two-cycle NST provided limited efficacy for resectability of inoperable mRCC, despite mild improvements in the BOR of the primary lesion and quality of life (Clinical Trial Registry 1041140-1).</P>