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RISS 인기검색어
- 검색키워드
- 저자 : Jinjin Guo (검색결과 5 건)
- 무료
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- 유료
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Modulation of lung cancer growth arrest and apoptosis by Phellinus Linteus
Guo, Jinjin,Zhu, Tongbo,Collins, LeaAnn,Xiao, Zhi-Xiong J.,Kim, Sung-Hoon,Chen, Chang-Yan Alan R. Liss, Inc 2007 Molecular carcinogenesis Vol.46 No.2
<P>The Phellinus Linteus (PL) mushroom has been shown to possess anti-tumor properties. Through influencing lymphocytes, PL indirectly augments the host's immune system against cancer cells. PL has also been demonstrated to reduce tumor proliferation. However, the mechanisms of PL against malignant growth have not yet been fully explored. In this study, we report that PL mediates the following two activities in mouse and human lung cancer cells: cell-cycle arrest at a low concentration of PL and apoptosis in response to a high dose of PL. After exposure to a low dose of PL, G<SUB>1</SUB> growth arrest occurred in the lung cancer cells. The negative growth control mediated by PL is evidenced by the decrease of the activities of cyclin-dependent kinases CDK2, 4, and 6. In contrast, at high doses, PL-induced lung cancer cells to undergo apoptosis in a dose-dependent fashion. This was evidenced by DNA fragmentation, caspase activation, and loss of clonogenecity in the lung cancer cells, all of which were lacking in the lung cancer cells treated with low concentrations of PL as well as the normal mouse lung epithelial cells exposed to either low or high concentrations of PL. The addition of the caspase inhibitor Z-VADfmk completely suppressed PL-induced apoptosis. Furthermore, the low dose of PL was able to synergize with doxorubicin to induce apoptosis in the lung cancer cells. Thus, our findings suggest that PL regulates two responses in the lung cancer cells: cell-cycle arrest and apoptosis. © 2006 Wiley-Liss, Inc.</P>
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A New Algorithm to Reduce the Mal-Operation of DOCR in Bi-directional Power Distribution Systems
Hongbin Wu,Jinjin Guo,Ming Ding 대한전기학회 2016 Journal of Electrical Engineering & Technology Vol.11 No.3
Considering the randomness and uncertainty of wind power, a reliability model of WTGs is established based on the combination of the Weibull distribution and the Markov chain. To analyze the failure mode quickly, we use the switch-section partitioning method. After defining the first-level load zone node, we can obtain the supply power sets of the first-level load zone nodes with each WTG. Based on the supply sets, we propose the dynamic division strategy of island operation. By adopting the fault analysis method with the attributes defined in the switch-section, we evaluate the reliability of the distribution network with WTGs using a sequential Monte Carlo simulation method. Finally, using the IEEE RBTS Bus6 test system, we demonstrate th
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Hongbin Wu,Jinjin Guo,Ming Ding 대한전기학회 2016 Journal of Electrical Engineering & Technology Vol.11 No.3
Considering the randomness and uncertainty of wind power, a reliability model of WTGs is established based on the combination of the Weibull distribution and the Markov chain. To analyze the failure mode quickly, we use the switch-section partitioning method. After defining the first-level load zone node, we can obtain the supply power sets of the first-level load zone nodes with each WTG. Based on the supply sets, we propose the dynamic division strategy of island operation. By adopting the fault analysis method with the attributes defined in the switch-section, we evaluate the reliability of the distribution network with WTGs using a sequential Monte Carlo simulation method. Finally, using the IEEE RBTS Bus6 test system, we demonstrate the efficacy of the proposed model and method by comparing different schemes to access the WTGs.
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Wu, Hongbin,Guo, Jinjin,Ding, Ming The Korean Institute of Electrical Engineers 2016 Journal of Electrical Engineering & Technology Vol.11 No.3
Considering the randomness and uncertainty of wind power, a reliability model of WTGs is established based on the combination of the Weibull distribution and the Markov chain. To analyze the failure mode quickly, we use the switch-section partitioning method. After defining the first-level load zone node, we can obtain the supply power sets of the first-level load zone nodes with each WTG. Based on the supply sets, we propose the dynamic division strategy of island operation. By adopting the fault analysis method with the attributes defined in the switch-section, we evaluate the reliability of the distribution network with WTGs using a sequential Monte Carlo simulation method. Finally, using the IEEE RBTS Bus6 test system, we demonstrate the efficacy of the proposed model and method by comparing different schemes to access the WTGs.
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Yunong Zhang,Jinjin Guo,Binbin Qiu,Yang Shi,Zhi Yang 제어로봇시스템학회 2017 제어로봇시스템학회 국제학술대회 논문집 Vol.2017 No.10
In this paper, a new formula called Zhang discretization 4-instant g-square with subtype Q (i.e., ZD4IgS_Q) is proposed, which is used for discretizing continuous-time zeroing neurodynamics (CTZN) model. Besides, in order to solve future nonlinear systems of equations (FNSoE), also termed discrete time-varying nonlinear systems of equations, a ZD4IgS_Q-type discrete-time zeroing neurodynamics (DTZN) model with O(g³) steady-state residual error pattern is acquired by adopting the formula ZD4IgS_Q. For comparison purposes, an Euler-type DTZN model with O(g²) steadystate residual error pattern is also presented. Abundant numerical experimental results show that, compared with Eulertype DTZN model, the ZD4IgS_Q-type DTZN model has better computational performance in terms of solving FNSoE.
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