Fast CU Encoding Schemes Based on Merge Mode and Motion Estimation for HEVC Inter Prediction

( Jinfu Wu ),( Baolong Guo ),( Jie Hou ),( Yunyi Yan ),( Jie Jiang ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.3

The emerging video coding standard High Efficiency Video Coding (HEVC) has shown almost 40% bit-rate reduction over the state-of-the-art Advanced Video Coding (AVC) standard but at about 40% computational complexity overhead. The main reason for HEVC computational complexity is the inter prediction that accounts for 60%-70% of the whole encoding time. In this paper, we propose several fast coding unit (CU) encoding schemes based on the Merge mode and motion estimation information to reduce the computational complexity caused by the HEVC inter prediction. Firstly, an early Merge mode decision method based on motion estimation (EMD) is proposed for each CU size. Then, a Merge mode based early termination method (MET) is developed to determine the CU size at an early stage. To provide a better balance between computational complexity and coding efficiency, several fast CU encoding schemes are surveyed according to the rate-distortion-complexity characteristics of EMD and MET methods as a function of CU sizes. These fast CU encoding schemes can be seamlessly incorporated in the existing control structures of the HEVC encoder without limiting its potential parallelization and hardware acceleration. Experimental results demonstrate that the proposed schemes achieve 19%-46% computational complexity reduction over the HEVC test model reference software, HM 16.4, at a cost of 0.2%-2.4% bit-rate increases under the random access coding configuration. The respective values under the low-delay B coding configuration are 17%-43% and 0.1%-1.2%.

Ginsenoside Rg1 supplementation clears senescence-associated β-galactosidase in exercising human skeletal muscle

Wu, Jinfu,Saovieng, Suchada,Cheng, I-Shiung,Liu, Tiemin,Hong, Shangyu,Lin, Chang-Yu,Su, I-Chen,Huang, Chih-Yang,Kuo, Chia-Hua The Korean Society of Ginseng 2019 Journal of Ginseng Research Vol.43 No.4

Background: Ginsenoside Rg1 has been shown to clear senescence-associated beta-galactosidase (SA-${\beta}$-gal) in cultured cells. It remains unknown whether Rg1 can influence SA-${\beta}$-gal in exercising human skeletal muscle. Methods: To examine SA-${\beta}$-gal change, 12 young men (age $21{\pm}0.2years$) were enrolled in a randomized double-blind placebo controlled crossover study, under two occasions: placebo (PLA) and Rg1 (5 mg) supplementations 1 h prior to a high-intensity cycling (70% $VO_{2max}$). Muscle samples were collected by multiple biopsies before and after cycling exercise (0 h and 3 h). To avoid potential effect of muscle biopsy on performance assessment, cycling time to exhaustion test (80% $VO_{2max}$) was conducted on another 12 participants (age $23{\pm}0.5years$) with the same experimental design. Results: No changes of SA-${\beta}$-gal were observed after cycling in the PLA trial. On the contrary, nine of the 12 participants showed complete elimination of SA-${\beta}$-gal in exercised muscle after cycling in the Rg1 trial (p < 0.05). Increases in apoptotic DNA fragmentation (PLA: +87% vs. Rg1: +133%, p < 0.05) and $CD68^+$ (PLA:+78% vs. Rg1:+121%, p = 0.17) occurred immediately after cycling in both trials. During the 3-h recovery, reverses in apoptotic nuclei content (PLA:+5% vs. Rg1 -32%, p < 0.01) and increases in inducible nitrate oxide synthase and interleukin 6 mRNA levels of exercised muscle were observed only in the Rg1 trial (p < 0.01). Conclusion: Rg1 supplementation effectively eliminates senescent cells in exercising human skeletal muscle and improves high-intensity endurance performance.

A Fast TU Size Decision Method for HEVC RQT Coding

( Jinfu Wu ),( Baolong Guo ),( Yunyi Yan ),( Jie Hou ),( Dan Zhao ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.6

The emerging high efficiency video coding (HEVC) standard adopts the quadtree-structured transform unit (TU) in the residual quadtree (RQT) coding. Each TU allows to be split into four equal sub-TUs recursively. The RQT coding is performed for all the possible transform depth levels to achieve the highest coding efficiency, but it requires a very high computational complexity for HEVC encoders. In order to reduce the computational complexity requested by the RQT coding, in this paper, we propose a fast TU size decision method incorporating an adaptive maximum transform depth determination (AMTD) algorithm and a full check skipping - early termination (FCS-ET) algorithm. Because the optimal transform depth level is highly content-dependent, it is not necessary to perform the RQT coding at all transform depth levels. By the AMTD algorithm, the maximum transform depth level is determined for current treeblock to skip those transform depth levels rarely used by its spatially adjacent treeblocks. Additionally, the FCS-ET algorithm is introduced to exploit the correlations of transform depth level between four sub-CUs generated by one coding unit (CU) quadtree partitioning. Experimental results demonstrate that the proposed overall algorithm significantly reduces on average 21% computational complexity while maintaining almost the same rate distortion (RD) performance as the HEVC test model reference software, HM 13.0.

Ginsenoside Rg1 supplementation clears senescence-associated β-galactosidase in exercising human skeletal muscle

Jinfu Wu,Suchada Saovieng,I-Shiung Cheng,Tiemin Liu,Shangyu Hong,Chang-Yu Lin,I-Chen Su,Chih-Yang Huang,Chia-Hua Kuo 고려인삼학회 2019 Journal of Ginseng Research Vol.43 No.4

Background: Ginsenoside Rg1 has been shown to clear senescence-associated beta-galactosidase (SA-β-gal) in cultured cells. It remains unknown whether Rg1 can influence SA-β-gal in exercising human skeletal muscle. Methods: To examine SA-β-gal change, 12 young men (age 21±0.2 years) were enrolled in a randomized double-blind placebo controlled crossover study, under two occasions: placebo (PLA) and Rg1 (5 mg) supplementations 1 h prior to a high-intensity cycling (70% VO2max). Muscle samples were collected by multiple biopsies before and after cycling exercise (0 h and 3 h). To avoid potential effect of muscle biopsy on performance assessment, cycling time to exhaustion test (80% VO2max) was conducted on another 12 participants (age 23±0.5 years) with the same experimental design. Results: No changes of SA-β-gal were observed after cycling in the PLA trial. On the contrary, nine of the 12 participants showed complete elimination of SA-β-gal in exercised muscle after cycling in the Rg1 trial (p < 0.05). Increases in apoptotic DNA fragmentation (PLA: +87% vs. Rg1: +133%, p < 0.05) and CD68+(PLA:+78% vs. Rg1:+121%, p=0.17) occurred immediately after cycling in both trials. During the 3-h recovery, reverses in apoptotic nuclei content (PLA:+5% vs. Rg1:-32%, p<0.01) and increases in inducible nitrate oxide synthase and interleukin 6 mRNA levels of exercised muscle were observed only in the Rg1 trial (p < 0.01). Conclusion: Rg1 supplementation effectively eliminates senescent cells in exercising human skeletal muscle and improves high-intensity endurance performance.

Impacts of Close-to-nature Management Technology on the Korean Pine Soil Chemical Properties in Northeast China

Wu, Yao,Qin, Kailun,Zhang, Jinfu,Li, Fengri Institute of Forest Science 2013 Journal of Forest Science Vol.29 No.4

Based on the guiding ideology of "Close-to-nature forestry", the soil chemical properties of Korean pine (Pinus koraiensis) plantation forest which was early done by canopy gap control were analyzed of Liangshui nature reserve in northeastern China. The results indicated that the nurture of forestry crevice diaphanous tended to improve the soil nutrient contents and significant differences of soil nutrients existed among different levels of soil for the same forest type of Korean pine. At 0< $H{\leq}20$ cm layer, the content of available nitrogen, available phosphorus, available potassium, total nitrogen and total phosphorus in artificial pure Korean pine forest are 640.28 $mg{\cdot}kg^{-1}$, 7.54 $mg{\cdot}kg^{-1}$, 275.91 $mg{\cdot}kg^{-1}$, 1.114% and 0.075%, they all higher than the other kinds of forests and for average 1.1 times, 1.4 times, 1.3 times, 1.6 times and 1.2 times. From the layer of $0<H{\leq}20$ cm to 20 cm < $H{\leq}40$ cm, soil nutrient indicators showed various degrees of decreasing in which organic matter had the greatest decline, decreasing by 170.64% while PH had the lowest decline, decreasing by 4.66%.

Impacts of Close-to-nature Management Technology on the Korean Pine Soil Chemical Properties in Northeast China

Yao Wu,Kailun Qin,Jinfu Zhang,Fengri Li 강원대학교 산림과학연구소 2013 Journal of Forest Science Vol.29 No.4

Based on the guiding ideology of “Close-to-nature forestry”, the soil chemical properties of Korean pine (Pinus koraiensis) plantation forest which was early done by canopy gap control were analyzed of Liangshui nature reserve in northeastern China. The results indicated that the nurture of forestry crevice diaphanous tended to improve the soil nutrient contents and significant differences of soil nutrients existed among different levels of soil for the same forest type of Korean pine. At 0<H≤20 cm layer, the content of available nitrogen, available phosphorus, available potassium, total nitrogen and total phosphorus in artificial pure Korean pine forest are 640.28 mgㆍkg-1, 7.54 mgㆍkg -1, 275.91 mgㆍkg-1, 1.114% and 0.075%, they all higher than the other kinds of forests and for average 1.1 times, 1.4 times, 1.3 times, 1.6 times and 1.2 times. From the layer of 0<H≤20 cm to 20 cm<H≤40 cm, soil nutrient indicators showed various degrees of decreasing in which organic matter had the greatest decline, decreasing by 170.64% while PH had the lowest decline, decreasing by 4.66%.

Longevity, tumor, and physical vitality in rats consuming ginsenoside Rg1

Chao-Chieh Hsieh,Chiung-Yun Chang,Tania Xu Yar Lee,Jinfu Wu,Suchada Saovieng,Yu-Wen Hsieh,Maijian Zhu,Chih-Yang Huang,Chia-Hua Kuo The Korean Society of Ginseng 2023 Journal of Ginseng Research Vol.47 No.2

Background: Effects of the major ginsenoside Rg1 on mammalian longevity and physical vitality are rarely reported. Purpose: To examine longevity, tumor, and spontaneous locomotor activity in rats consuming Rg1. Methods: A total of 138 Wistar rats were randomized into 2 groups: control (N = 69) and Rg1 (N = 69). Rg1 (0.1 mg/kg per day) were orally supplemented from 6 months of age until natural death. Spontaneous mobility was measured by video-tracking together with body composition (dual energy x-ray absorptiometry) and inflammation markers at 5, 14, 21, and 28 months of age. Results: No significant differences in longevity (control: 706 days; Rg1: 651 days, p = 0.77) and tumor incidence (control: 19%; Rg1: 12%, p = 0.24) were observed between the two groups. Movement distance in the control group declined significantly by ~60% at 21 months of age, together with decreased TNF-α (p = 0.01) and increased IL-10 (p = 0.02). However, the movement distance in the Rg1 group was maintained ~50% above the control groups (p = 0.01) at 21 months of age with greater magnitudes of TNF-α decreases and IL-10 increases. Glucose, insulin, and body composition (bone, muscle and fat percentages) were similar for both groups during the entire observation period. Conclusion: The results of the study suggest a delay age-dependent decline in physical vitality during late life by lifelong Rg1 consumption. This improvement is associated with inflammatory modulation. Significant effects of Rg1 on longevity and tumorigenesis were not observed.

New dammarane-type triterpenoid saponins from Panax notoginseng saponins

Qian Li,Mingrui Yuan,Xiaohui Li,Jinyu Li,Ming Xu,Di Wei,Desong Wu,Jinfu Wan,Shuangxi Mei,Tao Cui,Jingkun Wang,Zhaoyun Zhu 고려인삼학회 2020 Journal of Ginseng Research Vol.44 No.5

Background: Panax notoginseng saponin (PNS) is the extraction from the roots and rhizomes of Panax notoginseng (Burk.) F. H. Chen. PNS is the main bioactive component of Xuesaitong, Xueshuantong, and other Chinese patent medicines, which are all bestselling prescriptions in China to treat cardiocerebrovascular diseases. Notoginsenoside R₁ and ginsenoside Rg₁, Rd, Re, and Rb₁ are the principal effective constituents of PNS, but a systematic research on the rare saponin compositions has not been conducted. Objective: The objective of this study was to conduct a systematic chemical study on PNS and establish the HPLC fingerprint of PNS to provide scientific evidence in quality control. In addition, the cytotoxicity of the new compounds was tested. Methods: Pure saponins from PNS were isolated by means of many chromatographic methods, and their structures were determined by extensive analyses of NMR and HR-ESI-MS studies. The fingerprint was established by HPLC-UV method. The cytotoxicity of the compounds was tested by 3-(4,5-dimethylthiazol-2-yl)-2,5 -diphenyltetrazolium bromide assay. Results and Conclusion: Three new triterpenoid saponins (1e3) together with 25 known rare saponins (4 e28) were isolated from PNS, except for the five main compounds (notoginsenoside R₁ and ginsenoside Rg₁, Rd, Re, and Rb₁). In addition, the HPLC fingerprint of PNS was established, and the peaks of the isolated compounds were marked. The study of chemical constituents and fingerprint was useful for the quality control of PNS. The study on antitumor activities showed that new Compound 2 exhibited significant inhibitory activity against the tested cell lines.