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        Influence of Partial Replacement of NaCl with KCl on Formation of Volatile Compounds in Jinhua Ham during Processing

        Yingyang Zhang,Haizhou Wu,Jing Tang,Mingming Huang,Jianying Zhao,Jianhao Zhang 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.2

        The influence of partial replacement of NaCl with KCl on formation of volatile compounds during Jinhua ham processing was evaluated using GC/MS system. Jinhua ham was treated with either 100% NaCl (I) or 60% NaCl and 40% KCl (II). Formation of volatile compounds increased in Jinhua hams during processing for both salt formulations, particularly at the end of the salting period. There were differences in volatile compound formation between formulations I and II after 45 days of processing. Contents of lipid-derived volatiles (hexanal) and Strecker aldehydes (2-methylbutanal and 3- methylbutanal) were higher in Jinhua hams treated with formulation II after 45 days of processing. Partial salt replacement of NaCl with KCl changed formation of volatile compounds in Jinhua hams and may have affected the flavor of finished products.

      • KCI등재

        Effect of Monascus as a Nitrite Substitute on Color, Lipid Oxidation, and Proteolysis of Fermented Meat Mince

        Xiang Yu,Haizhou Wu,Jianhao Zhang 한국식품과학회 2015 Food Science and Biotechnology Vol.24 No.2

        Monascus spp. are fungi, traditionally eaten in Asian countries, that have the the potential to be used as a nitrite substitute in meat-product processing. Effects of using Monascus ruber MJ-1 as a nitrite substitute on color, lipid oxidation and proteolysis of fermented meat mince were investigated in this study. After 4 days of fermentation, a* and L* values for the samples were significantly higher and lower than the values for the control, respectively; however, b* values were significantly lower than that of the control throughout the fermentation process (p<0.05). Furthermore, Monascus ruber MJ-1 fermentation decreased the thiobarbituric acid reactive substances (TBARs) value and increased the myofibril fragmentation index (MFI) value of meat mince significantly (p<0.05). SDS-PAGE results further indicated that myofibrillar proteins were degraded during fermentation, while sarcoplasmic proteins were not. These results suggest prospects for the broad application of Monascus as a nitrite substitute in meat processing.

      • Kernel quaternion principal component analysis and its application in RGB-D object recognition

        Chen, Beijing,Yang, Jianhao,Jeon, Byeungwoo,Zhang, Xinpeng Elsevier 2017 Neurocomputing Vol.266 No.-

        <P><B>Abstract</B></P> <P>While the existing quaternion principal component analysis (QPCA) is a linear tool developed mainly for processing linear quaternion signals, the quaternion representation (QR) used in QPCA creates redundancy when representing a color image signal of three components by a quaternion matrix having four components. In this paper, the kernel technique is used to improve the QPCA as kernel QPCA (KQPCA) for processing nonlinear quaternion signals; in addition, both RGB information and depth information are considered to improve QR for representing RGB-D images. The improved QR fully utilizes the four-dimensional quaternion domain. We first provide the basic idea of three types of our KQPCA and then propose an algorithm for RGB-D object recognition based on bidirectional two-dimensional KQPCA (BD2DKQPCA) and the improved QR. Experimental results on four public datasets demonstrate that the proposed BD2DKQPCA-based algorithm achieves the best performance among seventeen compared algorithms including other existing PCA-based algorithms, irrespective of RGB object recognition or RGB-D object recognition. Moreover, for all compared algorithms, consideration of both RGB and depth information is shown to achieve better performance in object recognition than considering only RGB information.</P>

      • KCI등재

        Circumnavigation of a Moving Target in 3D by Multi-agent Systems with Collision Avoidance: An Orthogonal Vector Fields-based Approach

        Hang Zhong,Yaonan Wang,Zhiqiang Miao,Jianhao Tan,Ling Li,Hui Zhang,Rafael Fierro 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.1

        The problem of circumnavigating a moving target in a three dimensional setting by a network of agentswhile avoiding inter-agent collisions is addressed in this paper. A distributed control strategy is proposed for themulti-agent system to achieve three objectives: reaching the target plane with predesigned orientation, circulatingaround the target with prescribed radius, and avoiding collisions among agents. After representing the controlobjectives by three potential functions, the gradient fields of which are orthogonal to each other, the control lawthen is developed using the gradient vector field-based approach. The novelty of the proposed controller lies in theorthogonality of the vector fields, which decouples the control objectives and ensures global asymptotic convergenceto the desired motion, subject to some mild initial condition constraints. The stability and convergence analysis arepresented using Lyapunov tools, and the effectiveness of the proposed control strategy is demonstrated throughnumerical simulations.

      • KCI등재

        Pyrotinib Combined with Vinorelbine in Patients with Previously Treated HER2-Positive Metastatic Breast Cancer: A Multicenter, Single-arm, Prospective Study

        Kuikui Jiang,Ruoxi Hong,Wen Xia,Qianyi Lu,Liang Li,Jianhao Huang,Yanxia Shi,Zhongyu Yuan,Qiufan Zheng,Xin An,Cong Xue,Jiajia Huang,Xiwen Bi,Meiting Chen,Jingmin Zhang,Fei Xu,Shusen Wang 대한암학회 2024 Cancer Research and Treatment Vol.56 No.2

        Purpose This study aims to evaluate the efficacy and safety of a new combination treatment of vinorelbine and pyrotinib in human epidermal growth factor receptor 2 (HER2)–positive metastatic breast cancer (MBC) and provide higher level evidence for clinical practice. Materials and Methods This was a prospective, single-arm, phase 2 trial conducted at three institutions in China. Patients with HER2-positive MBC, who had previously been treated with trastuzumab plus a taxane or trastuzumab plus pertuzumab combined with a chemotherapeutic agent, were enrolled between March 2020 and December 2021. All patients received pyrotinib 400 mg orally once daily plus vinorelbine 25 mg/m2 intravenously or 60-80 mg/m2 orally on day 1 and day 8 of 21-day cycle. The primary endpoint was progression-free survival (PFS), and the secondary endpoints included the objective response rate (ORR), disease control rate (DCR), overall survival, and safety. Results A total of 39 patients were enrolled. All patients had been pretreated with trastuzumab and 23.1% (n=9) of them had accepted trastuzumab plus pertuzumab. The median follow-up time was 16.3 months (95% confidence interval [CI], 5.3 to 27.2), and the median PFS was 6.4 months (95% CI, 4.0 to 8.8). The ORR was 43.6% (95% CI, 27.8% to 60.4%) and the DCR was 84.6% (95% CI, 69.5% to 94.1%). The median PFS of patients with versus without prior pertuzumab treatment was 4.6 and 8.3 months (p=0.017). The most common grade 3/4 adverse events were diarrhea (28.2%), neutrophil count decreased (15.4%), white blood cell count decreased (7.7%), vomiting (5.1%), and anemia (2.6%). Conclusion Pyrotinib plus vinorelbine showed promising efficacy and tolerable toxicity as second-line treatment in patients with HER2-positive MBC.

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