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최정진(Jeongjin Choi),한민구(Mingu Han),임선우(Sunwoo Lim),이정기(Jungki Lee) 대한기계학회 2022 대한기계학회 춘추학술대회 Vol.2022 No.11
In this paper, the three-dimensional volume integral equation method (VIEM) is introduced for the analysis of an unbounded isotropic solid containing single isotropic/anisotropic spheroidal inclusions. A comprehensive analysis of three-dimensional elastostatic volume integral equation method (VIEM) is introduced for the analysis of an unbounded isotropic solid containing single isotropic/anisotropic spheroidal inclusions. In order to verify the three-dimensional volume integral equation method (VIEM) solutions, the VIEM solutions were compared to the exact solutions based on the Eshelby solution that evaluates the elastic fields inside and outside of an ellipsoidal inclusions for single isotropic/anisotropic spheroidal inclusions of arbitrary shape.
휴대형 자가발전기의 사용성 및 활용성 증대를 위한 UI 및 UX 개선
여정진(Jeongjin Yeo),홍정표(Jungpyo Hong),장도담(Dodam Jang),한솔(Sol Han),김혜일(Hyeil Kim),양윤석(Yoonseok Yang) 한국HCI학회 2014 한국HCI학회 학술대회 Vol.2014 No.2
본 연구에서는 기존의 휴대형 자가발전기들이 가지고 있는 여러 문제점들을 해결할 수 있는 Pulling 방식의 발전기 개발을 목표로, 새로운 생체역학적 구동 메커니즘의 적용을 통한 충분한 출력 성능 및 사용성과 활용성을 개선하기 위한 디자인 방안을 제시하였다. 인체의 동작을 이용하여 구동한다는 특수성을 고려한 새롭고 효과적인 구동메커니즘의 적용, 독특한 사용 방법과 사용 환경을 면밀히 고려한 UI 및 UX 결과, 1. 양손의 그립감 향상, 2. 야외활동을 고려한 부착가능형태, 3.상시착용이 가능한 형태 등의 디자인 결과물을 얻을 수 있었다. 본 연구에서 제안된 휴대형 자가발전기는 자가발전기술의 사용성과 활용성을 확대할 수 있을 것으로 기대된다. In this study, we suggested a design for novel human-powered generator with higher output performance by applying a new biomechanic driving method. We applied design strategies for effective and convenient power transfer from human body to generator. There was also consideration for extended portability. Among many results, 3 design plans were finally obtained which improved the grip-ability for both hands, portability and usability in outdoor activity, and even wearable. The human-powered portable generator suggested in this study is expected to expand the usability and utilization of generator. Further study considers the integration of sound and haptic feedback to make it fun experience to generate electricity through UI & UX design.
최정진(Jeongjin Choi),한민구(Mingu Han),임선우(Sunwoo Lim),이정기(Jungki Lee) 대한기계학회 2022 대한기계학회 춘추학술대회 Vol.2022 No.11
In this paper, the three-dimensional volume integral equation method (VIEM) is introduced for the analysis of an unbounded isotropic solid containing single isotropic/anisotropic spheroidal inclusions. A comprehensive analysis of three-dimensional elastostatic volume integral equation method (VIEM) is introduced for the analysis of an unbounded isotropic solid containing single isotropic/anisotropic spheroidal inclusions. In order to verify the three-dimensional volume integral equation method (VIEM) solutions, the VIEM solutions were compared to the exact solutions based on the Eshelby solution that evaluates the elastic fields inside and outside of an ellipsoidal inclusions for single isotropic/anisotropic spheroidal inclusions of arbitrary shape.
N, Vijayakameswara Rao,Han, Hwa Seung,Lee, Hansang,Nguyen, Van Quy,Jeon, Sangmin,Jung, Dae-Woong,Lee, Jeongjin,Yi, Gi-Ra,Park, Jae Hyung The Royal Society of Chemistry 2018 Nanoscale Vol.10 No.20
<P>Mesoporous silica nanoparticles (MSNs) with stimuli-responsive gatekeepers have been extensively investigated for controlled drug delivery at the target sites. Herein, we developed reactive oxygen species (ROS)-responsive MSNs (R-MSNs), consisting of a gadolinium (Gd)-DOTA complex as the ROS-responsive gatekeeper and polyethylene glycol (PEG)-conjugated chlorin e6 as the ROS generator, for magnetic resonance (MR) imaging-guided photodynamic chemotherapy. Doxorubicin (DOX), chosen as an anticancer drug, was physically encapsulated into DOTA-conjugated MSNs, followed by chemical crosslinking<I>via</I>the addition of GdCl3. DOX-R-MSNs could effectively maintain their structural integrity in a physiological environment for 7 days and show an enhanced<I>in vitro T</I>1-MR imaging signal for the Gd-DOTA complex. Upon 660 nm laser irradiation, the release rate of DOX from DOX-R-MSNs remarkably increased along with the disintegration of the gatekeeper, whereas DOX release was significantly retarded without irradiation. When DOX-R-MSNs were intravenously injected into tumor-bearing mice, they were effectively accumulated in tumor tissue, which was demonstrated using MR imaging. In addition, tumor growth was significantly suppressed by DOX-R-MSNs, allowing for site-specific release of DOX in a photodynamically maneuvered manner. Overall, these results suggest that R-MSNs have potential as drug carriers for MR imaging-guided photodynamic chemotherapy.</P>
Optogenetic control of body movements via flexible vertical light-emitting diodes on brain surface
Lee, Seung Hyun,Kim, Jeongjin,Shin, Jung Ho,Lee, Han Eol,Kang, Il-Suk,Gwak, Kiuk,Kim, Dae-Shik,Kim, Daesoo,Lee, Keon Jae Elsevier 2018 Nano energy Vol.44 No.-
<P><B>Abstract</B></P> <P>The microstimulation of specific neural populations of the brain is one of the facile and reliable methods used in neuroscience for deduction of functional movement, complex behavior and even long-range connectivity. Recent advanced biomedical tools now employ flexible optoelectronic devices combined with optogenetic mouse models to induce high spatiotemporal modulation of specific brain activity. However, most current applications are limited to activation of small functional regions using blue-light driven channelrhodopsin. In this report, we introduce flexible AlGaInP vertical light-emitting diodes (VLEDs) for perturbation of specific functional areas of mouse cortex. Micro-scaled LEDs effectively compress the conductive balls dispersed in anisotropic conductive film (ACF) resulting red light emissions with high optical power density, capable of stimulating motor neurons deep below layer III from the brain surface. Selective operation of pulsed red light from f-VLEDs induces mouse body movements and synchronized electromyogram (EMG) signals. The expression of chrimson, red-shifted channelrhodopsin, enables red-light excitation of targeted functional area of motor cortex. This demonstration opens new opportunities for entire cortical mapping, to explore the connectivity between undefined motor areas in the mouse brain.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The flexible vertical light-emitting diodes (f-VLEDs) were fabricated by an anisotropic conductive film (ACF). </LI> <LI> The f-VLEDs showed the optical power density more than 25mW/mm<SUP>2</SUP>, enough to stimulate the motor neurons below layer III. </LI> <LI> The f-VLEDs illuminated the frontal motor cortex of the mouse to control the body movements with minimal tissue damage. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>