Who Consumes Political News through YouTube?: An Application of the OMA Framework to YouTube Use in South Korea

JeongHun Han(JeongHun Han) 한국학술연구원 2022 Korea Observer Vol.53 No.4

This study analyzes how individual motivations including political interest and media trust and cognitive abilities affect news consumption through YouTube in a high choice media environment of South Korea. In the empirical analysis, we use a nationally representative dataset differentiating respondents in tree types of users concerning YouTube - namely, non-users, non-news consumers, and news consumers. Applying a binary response model with sample selection, we resolve a potential selectin bias and prove that political interest is the strongest motivation leading individuals to consume news through YouTube. In addition, the positive impact of political interest is shown to increases as individuals trust less traditional news media. However, we do not find any evidence that news consumption through YouTube is biased toward a specific party or ideological orientation.

[Free Paper] Effect of Berberine on p53 Expression by TPA in Breast Cancer Cells

Jeonghun Han,Sangmin Kim,Nam-Young Kim,Se Kyung Lee,Min-Young Choi,Jeonghui Lee,Jiyoung Kim,Seungpil Jung,Jee Soo Kim,Jung-Han Kim,Jun-Ho Choe,Jeong Eon Lee,Seok Jin Nam 대한외과학회 2011 대한외과학회 학술대회 초록집 Vol.2011 No.11

Rapid emergence and mechanisms of resistance by U87 glioblastoma cells to doxorubicin in an in vitro tumor microfluidic ecology

Han, Jeonghun,Jun, Yukyung,Kim, So Hyun,Hoang, Hong-Hoa,Jung, Yeonjoo,Kim, Suyeon,Kim, Jaesang,Austin, Robert H.,Lee, Sanghyuk,Park, Sungsu National Academy of Sciences 2016 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.113 No.50

<P>In vitro prediction of the probable rapid emergence of resistance to a drug in tumors could act to winnow out potential candidates for further costly development. We have developed a microfluidic device consisting of similar to 500 hexagonal microcompartments that provides a complex ecology with wide ranges of drug and nutrient gradients and local populations. This ecology of a fragmented metapopulation induced the drug resistance in stage IV U87 glioblastoma cells to doxorubicin in 7 d. Exome and transcriptome sequencing of the resistant cells identified mutations and differentially expressed genes. Gene ontology and pathway analyses of the genes identified showed that they were functionally relevant to the established mechanisms of doxorubicin action. Specifically, we identified (i) a frame-shift insertion in the filamin-A gene, which regulates the influx and efflux of topoisomerase II poisons; (ii) the overexpression of aldo-keto reductase enzymes, which convert doxorubicin into doxorubicinol; and (iii) activation of NF-kappa B via alterations in the nucleotide-binding oligomerization domain (NOD)-like receptor signaling pathway from mutations in three genes (CARD6, NSD1, and NLRP13) and the overexpression of inflammatory cytokines. Functional experiments support the in silico analyses and, together, demonstrate the effects of these genetic changes. Our findings suggest that, given the rapid evolution of resistance and the focused response, this technology could act as a rapid screening modality for genetic aberrations leading to resistance to chemotherapy as well as counter selection of drugs unlikely to be successful ultimately.</P>

Recapitulation of cancer stem cell niches in glioblastoma on 3D microfluidic cell culture devices under gravity-driven perfusion

Han, Jeonghun,Oh, Seunghan,Hoang, Hong-Hoa,Nguyen, Dao Thi Thuy,Lim, Wanyoung,Shin, Tae Hwan,Lee, Gwang,Park, Sungsu THE KOREAN SOCIETY OF INDUSTRIAL AND ENGINEERING 2018 JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY -S Vol.62 No.-

<P><B>Abstract</B></P> <P>The low survival rate of patients with glioblastoma is in part due to the heterogeneity in the cell population of glioblastoma that includes cancer stem cells (CSCs). CSC niches include a hypoxic core that is also closely linked to self-renewal ability, migration, and drug resistance. Here, we report a CSC culture method in three-dimensional microfluidic cell culture devices under gravity-driven perfusion, which we dub hypoxia chips (H-chips). In H-chips, glioblastoma cells, U87, spontaneously formed spheroids within 12h, even without any addition of growth factors. Compared to monolayer-cultured cells in dishes, spheroids in H-chips showed higher expression of CSC markers, such as hypoxia-inducible factor-1α (HIF-1α), CD133, and nestin. Spheroids in H-chips were more resistant to doxorubicin than monolayer-cultured ones in dishes. Transcriptional profiling revealed that the expression of interleukin-6 (IL-6), one of the inflammatory cytokines, was higher in spheroids in H-chips than in monolayer-cultured cells in dishes. IL-6 depleted cells failed to form spheroids in H-chips, and their drug resistance decreased. These results suggest that in H-chips, glioblastoma cells increased the production of IL-6, and promoted spheroid formation and other cancer stem cell properties, such as drug resistance. Our microfluidic cell culture method is highly useful for recapitulating CSC niches.</P>

Bureaucratic and Legislative Characteristics in the Representation of the International Marriage Migrant Women in Korea

Han Jeonghun(한정훈) 21세기정치학회 2013 21세기 정치학회보 Vol.23 No.1

This article examines the bureaucratic and legislative characteristics in the representation of the International Marriage Migrant Women (IMMW) in Korea. Three theoretical hypotheses are developed from the consideration of institutional effectiveness, political parties' issue ownership and legislative bureaucratic collaboration. Empirical Results show first that the fragmentation and overlaps of bureaucratic authorities over the issues of the IMMW tends to limit the effectiveness of policy implementation. Second, IMMW issues are not owned by the members of a specific political party. Finally, the representation of the IMMW in Korea is more likely to be led by the bureaucratic agencies located at the lower level of bureaucratic hierarchy through the legislative collaboration with the governing party legislators.

Responding to Public

Han JeongHun 한국국제정치학회 2007 國際政治論叢 Vol.47 No.5

여성할당 후보공천제 개혁과 여성정치인에 대한 수용성

한정훈 ( Jeonghun Han ) 서울대학교 한국정치연구소 2016 韓國 政治 硏究 Vol.25 No.3

<div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div>본 연구는 2000년 이후 여성할당 후보공천제 개혁의 효과를 분석한다. 특히, 제도개혁 결과가 후보공천과정에서 각 정당의 여성후보에 대한 수용성과 여성의원의 의정활동에 대한 유권자의 수용성에 미치는 효과를 경험적으로 검증한다. 연구결과는 두 가지 흥미로운 결과를 제시하였다. 첫째, 여성할당 후보공천제도의 개혁은 한국 사회 내 각 정당이 여성후보 공천의 수 및 지역적 분포를 확대하는데 유의미한 영향력을 미쳤다. 둘째, 여성할당 후보공천제도의 개혁은 여성의원의 의정활동에 대한 유권자의 긍정적인 평가에는 유의미한 영향력을 지니지 못했다. 여성할당 후보공천 제도의 발전에도 불구하고 유권자들은 남성의원에 비해 여성의원의 의정활동을 더욱 긍정적으로 평가하지는 않았다. 본 연구결과는 여성할당 후보공천제도의 개혁은 여성정치인에 대한 유권자 의식 변화를 수반할 수 있는 방향으로 발전해갈 필요성을 제기한다. This article analyzes the influence of the candidate selection law with gender quotas reformed after 2000. In particular, it empirically tests the effect of the institutional reform on parties` acceptability of female candidates and pubic acceptability of female representatives. Results show two interesting points. First, the institutional reform on the gender quotas has significantly influenced on the increase in the number of female candidate and the enlargement of the regions in which female candidates are nominated. Second, the pubic acceptability of female representatives has not been improved by the reform. The legislative performance of female representatives is not much more positively assessed than that of male representatives by public. These outcomes imply that any institutional reform on gender quotas in the future might build the measures to develop the positive acceptability of female politicians by pubic.

유권자와 정당의 연계성(linkage)

한정훈(Jeonghun Han) 명지대학교 미래정치연구소 2013 미래정치연구 Vol.3 No.1

본 연구는 지역과 정당과의 피상적 연계성이 약화되면서 나타난 한국 정당정치의 위기에 대응하여 한국 정당들이 유권자와의 연계성을 강화할 수 있는 방안을 모색하고자 한다. 이를 위해 초국적 정당인 유럽사회당의 유럽의회 내 원내정당이라 할 수 있는 유럽진보연합에 대한 문헌 자료 수집과 기술적 사례분석을 시도하였다. 특히 1979년 이후 유럽사회당의 메니페스토 및 상징물의 변화를 분석하였다. 연구결과는 유럽통합 초기부터 유럽사회당의 회원국 정당들 간 정책 공조의 노력은 유권자에게 지속적으로 일관된 정책적 입장을 전달해 왔음을 보여준다. 이러한 정책적 일관성은 유럽사회당의 유럽의회 내 원내정당이라 할 수 있는 유럽진보연합의 득표율 및 유럽연합 회원국들의 투표율의 안정성과 일정 정도 연관성이 있음이 드러났다. This article explores a way of improving the linkage between Korean voters and parties in response to the current crisis of party politics in Korea. In so doing, it performs a descriptive analysis of the policy consistency at the Party of the European Socialists(PES), a part of whose members consists of the Progressive Alliance of Socialists and Democrats (S&D) in the European Parliament. Results from the analysis of the party’s official documents such as party manifestoes show that the arty has made enduring efforts to deliver consistent policy positions to their supporters in Europe. In addition, high turnout rates in the European elections among the old member states and low rates of defection from party support show that the policy consistency of the party may help to develop a stable party support among European voters.

정당의 후보 경선과 유권자 인식: 제19대 대선의 주요 정당을 중심으로

한정훈 ( Jeonghun Han ) 경남대학교 극동문제연구소 2017 한국과 국제정치 Vol.33 No.3

본 연구는 한국 사회에서 정당의 후보경선제도 변화와 그 효과를 분석한다. 특히 유권자 참여를 강화하고자 한 각 정당의 후보경선제도 변화가 후보경선과정에 대한 유권자의 인식을 향상시켰는지를 살펴본다. 우선 제도적 측면에서, 제19대 대선과정에서 각 정당의 경선제도는 유권자의 참여를 확대하려는 제16대 대선 이후의 개혁 방향에 부합한다는 특징이 있다. 다음으로 유권자의 인식적 측면에서, 제19대 대선과정에서 과반의 한국 유권자들이 정당의 후보경선과정을 인지하였다. 특히 대선 직후 유권자 의식조사자료에 의하면, 더불어민주당과 정의당에 대한 정당일체감을 지닌 유권자와 이념적으로 극단적 우파성향의 유권자가 정당의 후보경선과정을 상대적으로 더욱 잘 인지하였다. 또한 정치 및 선거에 대한 관심과 SNS을 통해 정치정보를 획득하려는 유권자의 노력은 정당의 후보경선제도를 인지하는 데 도움이 되었다. 이와 같은 결과는 한국 정당의 후보경선과정이 유권자와의 연계성을 증진할 수 있는 절차적 잠재력을 지닌다는 것을 함의한다. This article studies the institutional changes of political parties in their primary elections for Korean Presidency. In particular, it analyzes whether and how those changes affect voters’ perception on the electoral events. In answering these questions, this article first finds that the primary elections of political parties in the 19th presidential election have consistently maintained the reformation trends since the 16th presidential election in which parties have improved their institutional measures to mobilize more voters into their primary elections. Second, through the survey data analysis, three factors in fact are relevant to voters’ perception on parties’ primary elections: ideological extremism, political information through SNS, and party identification. In particular, those who identify themselves as members of either the Minju party or the Justice party and have extreme right ideology are more likely to recognize the primary elections. These findings imply that parties’ primary elections might be a good channel to enhance the relationship between parties and their supporters in Korea.

벤죠엔슬 픽업트럭의 록업 부밍개선 연구

한정훈(Jeonghun Han),한일현(Ilhyun Han),김춘휴(Choonhyu Kim),유철하(Chul-Ha Yu) 한국자동차공학회 2018 한국자동차공학회 학술대회 및 전시회 Vol.2018 No.11

A pickup truck with rear banjo type axle has a problem of lock-up booming noise and vibration which is caused by rear axle pitch mode and frame bending mode at low rpm. This paper classifies the problem and suggests for countermeasure in view of source, transfer path and response.