Skin entrance dose for digital and film radiography in Korean dental schools

Cho, Eun-Sang,Choi, Kun-Ho,Kim, Min-Gyu,Lim, Hoi-Jeong,Yoon, Suk-Ja,,Kang, Byung-Cheol 대한구강악안면방사선학회 2005 Imaging Science in Dentistry Vol.35 No.4

Purpose : This study was aimed to compare skin entrance dose of digital radiography with that of film radiography and to show the dose reduction achievement with digital systems at 11 dental schools in Korea. Materials and Methods : Forty six intraoral radiographic systems in 11 dental schools were included in this study. Digital sensors were used in 33 systems and film was used in 13 systems. Researchers and the volunteer visited 11 dental schools in Korea. Researchers asked the radiologic technician (s) at each school to set the exposure parameters and aiming the x-ray tube for the periapical view of the mandibular molar of the volunteer. The skin entrance doses were measured at the same exposure parameters and distance by the technician for each system with a dosimeter (Multi-O-Meter : Unfors instruments, Billdal, Sweden). Results : The median dose was 491.2 μGy for digital radiography and 1,205.0 μGy for film radiography. The skin entrance dose digital radiography was significantly lower than that of film radiography (p<0.05). Conclusion : Fifty-nine percent skin entrance dose reduction with digital periapical radiography was achieved over the film radiography in Korean dental schools.

Three-Dimensional Porous Collagen/Chitosan Complex Sponge for Tissue Engineering

Kim, Sung Eun,Cho, Yong Woo,Kang, Eun Jung,Kwon, Ick Chan,Lee, Eunhee Bae,Kim, Jung Hyun,Chung, Hesson,Jeong, Seo Young The Korean Fiber Society 2001 Fibers and polymers Vol.2 No.2

A three-dimensional, porous collagen/chitosan complex sponge was prepared to closely simulate basic extracellular matrix (ECM) constitutes, collagen and glycosaminoglycan. The complex sponge was prepared by a lyophilization method and had the regular network with highly porous structure, suitable for cell adhesion and growth. The pores were well interconnected, and their distribution was fairly homogeneous. The complex sponge was crosslinked using 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide (EDC) and N-hydroxysuccinimide (NHS) to increase its boilogical stability and enhance its mechanical properties. The crosslinking medium has a great effect on the inner structure of the sponge. The homogeneous, porous structure of the sponge was remarkably collapsed in an aqueous crosslinking medium. However, the morphology of the sponge remained almost intact in a water/ethanol mixture crosslinking milieu. Mechanical properties of the collagen/chitosan sponge were significantly enhanced by EDC-mediated crosslinking. The potential of the sponge as a scaffold for tissue engineering was investigated using a Chinese hamster ovary cell (CHO-K1) line.

경부에 발생한 침습성 지장종의 치험례

조은영,하종운,김영빈,정윤심 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.2

Lipomas make up 4∼5% of all benign tumors in the body and are most often located on shoulders and backs. Neck lipomas are often developed in the subcutaneous tissues of the posterior neck, Most lipomas have slow growth rate and the recurrence is very rare after surgical excision because of well-defined border. But lipoma originated from muscles(intramuscular and intermuscular lipoma), so called infiltrating lipoma, has ill-defined border and little or no evidence of encapsulation. Histologically the feature of infiltrating lipoma is distinctive. There is a consistent infiltration with dissociation of the surrounding muscle fibers. The overall recurrence rate is less than 5%, but rises to 62.5% when deep infiltrating lipomas are considered separately. Thus infiltrating lipoma is best excised with a margin of normal muscle to avoid recurrence. Its location in the head and neck is uncommon. 18 cases of infiltrating lipoma in the head and neck has been reported to date. Here we report a case of infiltrating lipoma that arises in the head and neck muscle with a review of the literature on the subject.

An Analysis of Diplomatic Relations between the Republic of Korea and the Republic of Kazakhstan, and Its Prospects

Cho,Eun-Jeong,Kim,German N 고려대학교 러시아 CIS연구소 2012 Acta Russiana Vol.4 No.-

В 2012-ом году Республика Корея и Республика Казахстан отмечают 20- летие установления дипломатических отношений. В данной статьи рассматривается, какие внешние и внутренние детерминанты оказывали решающие влияние на создание, применение и дополнение внешней политики Республики Корея в отношений Казахстана с того момента, когда обе страны установили дипломатических отношений. Теория процесса принятия решений внешней политики, которая развивалась в основном в рамках послевоенной американской политологии с середины 20 века, показывает, что в отличии от традиции "реалистической" теории в современном мире "разные" факторы через "сложный и многослойный" процесс оказывают влияние на создание и применение дипломатической политики, и её результаты имеют обратную связь и принимаются во внимание в последующем потоке деятельности. В течение 20 лет дипло-матических связей южнокорейско казахстанские отношения развивались через три периода. Это во-первых, период образования отношений с момента установления дипломатических отношений в начале 90-ых годов до азиатского финансового кризиса в конце 90-х годов, во-вторых, период развития связей на основе экономического и ресурсного сотрудничества с начала 2000-ых годов до прихода к власти нынешней администрации в 2007 году и, в-третьих, период диверсификации отношений не только в экономическом, но и в политическом, культурном, социальном секторах с прихода к власти нынешней администрации Ли Мён Бака в 2008 году до сегодняшнего дня. В данной статьи рассматривается, какие именно внешние и внутренние факторы во вышеуказанных 3 периодах сыграли главную роль во принятии дипломатического курса Республики Корея в отношении Казахстана и намечаются, какие особенности существуют в Южнокорейско-Казахстанских отношениях во время развития дипломатических отношений обеих стран.

시중 판매중인 Fresh-Cut 채소 제품의 품질평가

조순덕,박주연,김은정,김동만,김건희 덕성여자대학교 대학원 2007 덕성여자대학교 대학원 논문집 Vol.9 No.-

Fresh-cut 채소 제품이 소비자에 의해 선택되어 소비되려면 이의 친환경적 원료생산과 가공, 포장, 서빙에 이르는 전 과정에서 체계적인 품질관리가 이루어져야 하며 갈변제어, 연화제어 및 미생물적 제어 등 관련 기술의 연구개발이 요구된다. 본 연구에서는 시중 유통 · 판매되고 있는 fresh-cut 채소제품의 품질을 비교평가하기 위해 현재 유통되고 있는 9개사 제품을 선정하였으며, 관능검사를 포함하여 vitamin C, 무기질, 중금속 함량, 잔류농약 및 미생물오염 정도를 조사하였다. 관능평가에서는 갈변 등 품질변화로 인해 전반적인 기호도가 그다지 높지 않았다. 채소류에서 중요 영양성분인 vitamin C 함량은 9개사 모든 제품의 주재료인 양상추에서 거의 검출되지 않았고 다른 채소류의 vatimin C 함량 역시 식품성분표보다 소량이었다. 무기질 함량 역시 극히 소량이었는데, 이는 박피, 절단 등의 최소 가공 공정을 거치면서 파괴되기 쉬운 vitamin C와 무기질이 대부분 손실되었기 때문으로 사료된다. 안전성측면에서 평가한 잔류 중금속 함량의 경우 몇 개의 제품에서 구리와 납이 소량 검출되었으며 잔류농약은 검출되지 않았다. Most fresh-cut agri-food products are less stable than the unprocessed materials from which they are made. The objective of this study was the development of a quality control system for fresh-cut agri-food products. In this study, the vitamin C, mineral, residual heavy metal contents and pesticides of various fresh-cut agri-food products were analysed. Through the sensory evaluation, the reason for the lower than expected overall acceptability in most products is that cut products are likely to cause browning and easily lose their freshness. Therefore, the postharvest technology that can maintain the quality, freshness and appearance must be supplied. Vitamin C contents did not exist in all salad products of the selected 9 companies, although vitamin C and mineral contents that are main nutrients that can be supplied mainly in salads. The results showed that vitamin C and mineral contents were very small and extremely small in other vegetables compared with the standard of a food ingredient, It is possible that vitamin C and most minerals are easily destroyed were lost through the minimal process like peeling and cutting. In safety side, the remaining heavy metal contents of fresh-cut agri-food were investigated and the results showed that copper and lead existed in some products because cadmium in agricultural produce is only controlled by the minimum standard of heavy metal contents in Korea. No residual pesticides were detected in all products.

대장암종에서 암관련 유전자들의 Promoter Methylation과 암종 발생 및 진행과의 관게에 대한 연구

정동준,이정은,민영기,조성우,백무준,양승하,김의한,김창진 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

The colorectal corcinoma is one of the most common malignant tumor in Korea and its carcinogenic mechanism has not been elucidated exactly yet. So far, the most common carcinogenic mechanism has been known to be multiple genetic changes. But, the CpG island hypermethylation has been revealed to be one of the most important carcinogenic mechanism second to the genetic changes. The epigenetic changes characteristically imprint and transfer to the next generation without changes of nucleotide sequences. When the CpG island of promoter or 5'- exon 1 of a specific gene is methylated by DNA methyltrasferases (DNMTs), the gene expression is inhibited. Carcinogenic mechansisms by promoter methylation has been well known, but the progression of the cancer has not been elucidated yet. The molecular researches on the carcinogenic mechanisms largely depended on the tumor tissue containing various components of cell, due to difficulties in harvesting pure homogeneous tumor cells. Promoter methylatonof the cancer related genes as APc, hMLH2, p16, DAP-K and MGMT in 50 cases of sporadic colorectal carcinoma was studied. The pure normal colorectal epithelial cells, and cancer cells from superficial and deep invasive portion were harvested respectively by laser captured microdissection(LCM), and DNA was extracted from them. The promoter methylation was studied by methylation specific poymerase reaction (MSP) after bisulfite modification of the DNA and the expression of the genes by immunohistochemistry. The results suggests that promoter methylation of the cancer related genes are closely related with the colorectal carcinogenesis and it occurrs from early phase of carcinogenesis, progressing constantly to the late stage. And the promoter methylation of normal epithelial cells increased by age. The p15, known to be the genes related to hematologic malignancy, was closely related to the colorectal carcinoma as well.

혈압측정의 정확성 평가

조성현,황정해,김은경,오병희,김창엽 한국의료QA학회 1996 한국의료질향상학회지 Vol.3 No.1

Background : Blood pressure is an important indicator in diagnosis and assessing treatment of a patient. Clinical staffs use blood pressure on the assumption that measured value is accurate and reliable. However, whether measured blood pressure is accurate has been rarely investigated in Korea. Objectives : The aims of this study are to evaluate clinical staffs' knowledge and technique as well as accuracy of sphygmomanometer. Also the program to improve the measurement is developed. Methods : Seventy-three registered nurses were asked nine multiple choice questions including Korotkoff sound, cuff size, and deflation rate. Simultaneously characteristics of nurses were examined age, working place, duration of employment and academic degree. A testing videotape(Standardizing Measurement Video-Tutored Course) was used for evaluating the accuracy of measurement. Testees were to read and record the 12 cases of blood pressure measurement, watching a falling mercury column and hearing Korotkoff sounds. After 10 minutes' education, they were again tested with the same cases. Additionally, 83 mercury sphygmomanometers were checked to find defects such as inaccurate calibration and zero setting, leaky bladder, etc. Results : For the knowledge testing correct response rate was 41.1%. They were the lowest in selecting the proper cuff size and Korotkoff sound. In examining accuracy of blood pressure with videotape, nurses had 67.7% correct response rate. The correct response rate was significantly improved by a session of education. About 23% of sphygmomanometers was without discemable defects. Conclusion : The knowledge and skill of clinical staffs along with the accuracy of equipment have to be improved. A properly designed education program would contribute to the accuracy improvement of blood pressure measurement. Also, more concerns should be given to the precision and maintenance of equipment.

개의 아토피 피부염에 대한 Leflunomide의 임상적 적용 1례

홍은지,윤기영,서경원,최호정,정성목,송근호,조종기,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

A Shih-tzu(8-year-old, castrated male) was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with the history of relapsing pruritus, recurrent dermatitis. On the physical examination, generalized erythema, otitis externa, alopecia and lichenification were observed. Using Favrot's criteria for diagnishing atopic dermatitis, 7 criteria were satisfied out of 8 criteria. After treatment for infection, intradermal skin test was performed(positive allergen : Df, Dp). And then immunotherapy was performed, but clinical signs were not getting better. Next treatment of glucocorticoid shown little improvement of clinical signs, and adverse effect(diarrhea) was shown after cyclosporine application. So application of leflunomide which is used for human atopic dermatitis treatment in some case was planned. After 6 months of application of leflunomide, clinical signs were decreased gradually.

실내공기 중 미세분진(PM2.5)에 대한 측정 및 분석 표준화 방안 연구

조은정,조영민 慶熙大學校 地球環境硏究所 2002 지구환경논문집 Vol.13 No.-

주요 오염원 물질로 취급되는 미세분진 중 PM2.5 미세 입자의 시료채취 및 측정 방법의 표준화 제정을 위해, 대표적인 시료포집방법인 여과 채취에 의해 질량농도를 나타내는 관성 분리법과 자상 물질의 물리적 성질을 이용하는 상대 농도계인 광산란 분진계를 비교하였다. 관성분리법을 이용한 샘플러는 현재 국내에서 실내 공기질 측정용으로 가장 많이 쓰이는 mini vol과 EPA 방법에 의해 설계된 PM2.5 샘플러를 선정하였고, 광산란법을 적용한 샘플러에는 각기 질량농도계와 개수농도계를 선정하여 장치의 특성을 비교 검토하였다. 그 밖의 실험 환경에 대한 기본조건인 측정시간, 측정위치등과 실험 측정 횟수에 따른 신뢰도구간의 확인과 임팩터 효율의 측정을 하였다. 그리고, 분진의 측정에 있어서 측정 장소, Sampler의 위치 등은 그 주변지역의 오염도를 대표할 수 있고, 시설을 이용하는 사람이 많은 곳을 선정하되, 환기구나 창문, 문 등의 환기에 영향을 적게 받는 지역에, 사람의 호흡기의 높이에 설치해야 한다는 것을 확인하였다. 또한 분진의 샘플링 시간 역시 중요한 인자로서, 주변환경에 대한 선행조사 이후에 적합한 샘플링 시간을 정하는 것이 의미가 있으며 몇가지 대표적인 측정 장치의 실험 데이터의 신뢰성을 위해서는 적어도 3회 이상의 반복실험이 이루어져야 함을 알 수 있었다.

피부 병변을 동반한 악성조직구증 1예

조은택,박용관,김진호,강정원,천영욱,전익섭,박유환,전춘해 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

Malignant histiocytosis, originally described in 1939 as histiocytic medullary reticulosis by Scott and Robb-Smith, is a rare histiocytic proliferative disorder that often shows an acute onset and used to progress to death within a few months. This disorder characterized clinically by fever, generalized weakness, lymphadenopathy and hepatosplenomegaly, and shows a variable range of pancytopenia. Extranodal involvement is common, with an incidence ranging from 50% to as high as 90%, skin involves8ment was noted in 10% to 15%. Typical skin lesions were mainly founded in extremity. i.e. erythematous papule and nodule occasionally become to necrosis and ulceration. We experienced one case of malignant histiocytosis in a 46-years-old female. The major clinical findings are fever, malaise, hepatosplenomegaly and erythematous skin lesion. In the laboratory study, pancytopenia is noted on the peripheral blood. And also aggregation of many atypical histiocytes were shown on skin and bone marrow biopsy. So we reported one related case with malignant histiocytosis as well as reviewing literature .