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Nonequilibrium Backreaction on a Moving Charge and Mirror in Quantum Fields
Jen-Tsung Hsiang,Da-Shin Lee,Chun-Hsien Wu 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.2I
Backreaction on a nonrelativistic moving charge and mirror under the influence of quantum fields is studied. We employ the closed-time-path formalism to obtain the influence functional by tracing out quantum fields. The respective semiclassical Langevin equation is derived and can be used to describe the stochastic behavior on its mean trajectory with a self-consistent backreaction. In particular, when backreaction dissipation and fluctuations are taken into account, the corresponding fluctuation-dissipation theorem obtained from the first-principles derivation must be fulfilled. The implications of the results from solving the semiclassical Langevin equation are discussed.웗
Antioxidative and Hepatoprotective Effects of Magnolol on Acetaminophen-induced Liver Damage in Rats
Yung-Hsiang Chen,Feng-Yen Lin,Po-Len Liu,Yi-Tsau Huang,Jen-Hwey Chiu,Yi-Chun Chang,Kee-Ming Man,Chuang-Ye Hong,Yen-Yi Ho,Ming-Tsung Lai 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.2
Acute liver failure (ALF), an often fatal condition characterized by massive hepatocyte necrosis, is frequently caused by drug poisoning, particularly with acetaminophen (N-acetyl-p-aminophenol/APAP). Hepatocyte necrosis is consecutive to glutathione (GSH) depletion and mitochondrial damage caused by reactive oxygen species (ROS) overproduction. Magnolol, one major phenolic constituent of Magnolia officinalis, have been known to exhibit potent antioxidative activity. In this study, the anti-hepatotoxic activity of magnolol on APAP-induced toxicity in the Sprague-Dawley rat liver was examined. After evaluating the changes of several biochemical parameters in serum, the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) were elevated by APAP (500 mg/kg) intraperitoneal administration (8 and 24 h) and reduced by treatment with magnolol (0.5 h after APAP administration; 0.01, 0.1, and 1 μg/kg). Histological changes around the hepatic central vein, lipid peroxidation (thiobarbituric acid-reactive substance/TBARS), and GSH depletion in liver tissue induced by APAP were also recovered by magnolol treatment. The data show that oxidative stress followed by lipid peroxidation may play a very important role in the pathogenesis of APAP-induced hepatic injury; treatment with lipid-soluble antioxidant, magnolol, exerts anti-hepatotoxic activity. Our study points out the potential interest of magnolol in the treatment of toxic ALF.
Quantum Noise on a Point Charge from Electromagnetic Squeezed Vacuum Fluctuations
Tai-Hung Wu,Da-Shin Lee,Jen-Tsung Hsiang 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.57 No.31
The effect of quantum noises on a point charge from electromagnetic squeezed vacuum fluctuations is studied. Here a novel reduction phenomenon in velocity dispersion is found in the situation when the particle barely moves. It shows that the velocity dispersion of the charge can be reduced below the value solely given by the normal vacuum states of the electromagnetic fields by using an appropriate choice of the squeeze parameters. This may be viewed as a transient phenomenon. Optimally utilizing this reduction scheme for gravitational wave detection is possible, but challenging.