SDN controller detection Openflow software

Jea-Rin Kim,Muhammad Afaq,Gwan-Woo Kang,Wang-Cheol Song 중소기업융합학회 2015 중소기업융합학회 국제학술대회논문집 Vol.2 No.1

도심하천의 조망경관이 아파트 실거래가에 미치는 영향 : 대구 신천변 중심으로

김동준 ( Kim Dong Jun ),김혜린 ( Kim Hye Rin ),황재훈 ( Hwang Jea Hoon ) 충북대학교 건설기술연구소 2017 建設技術論文集 Vol.36 No.1

사회적·경제적 여건이 양호해 짐에 따라 시민들의 삶의 질이 크게 향상되었다. 이에 따라 주거의 물리적 특성 뿐 아니라 환경적 측면의 영향력이 크게 대두되고 있는 가운데 본 연구는 대구 대표 도심 하천인 신천의 조망이 가능한 공동주택 을 대상으로 하천 조망이 아파트 가격에 얼마나 영향을 미치는지에 대한 분석을 위한 연구이다. 해당 지역의 대상지를 정해 자료를 구축하여 `V-World desktop` 프로그램으로 조망범위를 분석한 뒤 신천 변 녹지까지 포함한 지역의 면적을 분석하였다. 다른 단지 특성과 사회적인 특성을 고려하여 아파트 조망권이 아파트 매매가에 미치는 영향에 대해 특성감안가격모형(헤도닉함수)을 이용하여 분석을 하였는데, 신천조망은 매매가에 거의 영향을 주지 않는 것으로 나타났다. 그러므로 대구 도심 하천인 신천 조망권의 거주자를 비롯한 아파트 구매자 들에게 가치가 그리 크지 않다고 볼 수 있다. As the social and economic conditions have improved, the quality of life of citizens has improved greatly. As a result, not only the physical characteristics of the residence but also the influence of the environment have been greatly increased. The purpose of this study is to analyze the effect of river view on the price of apartments in apartment complexes with viewpoint of Sincheon, a city center river in Daegu. We constructed the data for the target area of the area and analyzed the scope of the view through the `V-World desktop` program and analyzed the area of the area including the Sincheon―dong green tract. Considering the characteristics of other complexes and social characteristics, the effect of the apartment view rights on the apartment sale price was analyzed using the characteristic pricing model (hedonic function), and the Sincheon view had little effect on the selling price.

Sufficient Calorie Intake Ameliorates Cognitive Impairment in Alcoholic Liver Disease

( Ye Rin Choi ),( Min Jea Shin ),( Gi Soo Youn ),( Sang Jun Yoon ),( Haripriya Gupta ),( Na Young Lee ),( Hyeong Seop Kim ),( Dong Joon Kim ),( Ki Tae Suk ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1

Aims: Alcoholic liver disease (ALD) is the most common cause of chronic liver disease. And cognitive dysfunction is one of the complications and associated with calorie intake in ALD. However, relation between nutrition and cognitive function has not been fully evaluated. The aim of this study is to explore the effect of diet on cognitive function in ALD. Methods: A total of 43 patients were enrolled and neuropsychological tests assessed according to the nutritional state (BMI<21.7 and BMI≥21.7). In animal study, mice were sub-divided into 4 groups (n=9/group; control (5% EtOH liquid diet), low fat (5% EtOH+low fat diet), high fat (5% EtOH+high fat diet), and high protein (5% EtOH+high protein diet)) for 8 weeks. For the cognitive function, we performed T-maze study weekly before and after alcohol binge. Results: In the comparison of cognitive function (BMI<21.7 and BMI≥21.7), language score of Korea mini-mental state (7.37 ± 1.4 and 7.85 ± 0.4 P=0.04), rey-complex figure (72.0±25.9 and 58.4±33.6, P=0.05), boston naming (11.7±2.7 and 13.0±1.8, P=0.02), forward digit span (6.7±1 .8 and 7.5±1.6, P=0.04), Korean-color word stroop (24.2±26.5 and 43.6±32.4, P=0.006), interference score (33.9±31.9 and 52.3±33.9, P=0.02) showed high scores in BMI≥21.7 group. In the animal study on day 40, all groups shortened the time to find feed (low fat: P=0.004, high fat: P=0.02) compared to the control group. Interestingly, binge drinking mice reduced the time than before trained mice. Conclusions: ALD patients with BMI<21.7 enhance their cognitive dysfunction. Although it needs more studies which correlation of calorie intake and cognitive function, this study indicates that sufficient intake of calories provides major benefits for preventing cognitive dysfunction.

다구찌 실험계획법을 이용한 소구경화기 총열 내부용 Cr-Mo-V강의 질화공정 최적화

권혁린(Hyuk-Rin Kwon),김동은(Dong-Eun Kim),손형동(Hyung-Dong Son),신재원(Jea-Won Shin),박재하(Jae-Ha Park),강명창(Myung-Chang Kang) 한국기계가공학회 2018 한국기계가공학회지 Vol.17 No.3

When shooting small arms, the inner surface temperature is heated up to about 700~1,000℃ by the friction of the bullet and the inner wall of the barrel and the combustion of propellant. High-temperature propellant gas and high-speed movement of the bullet cause corrosion of the inner wall, which is noticeable immediately in front of the chamber. In this study, the mechanical properties of Cr-Mo-V steel, which is the base material, were tested using Taguchi experimental design to find the best nitriding treatment conditions. For the nitriding process, the working time, salt bath temperature, and salt concentration were combined as three conditions and placed in the L9(3⁴), orthogonal array table. The thicknesses of the white layer and the nitrogen diffusion layer were measured after nitriding under each condition in a salt bath furnace. Durability was evaluated by measuring the degree of dispersion through actual shooting because it was difficult to evaluate the mechanical properties of the cylinder inner structure. As a result, it was confirmed that the durability was optimal at 565℃, 1 hour, 0.5%. These optimal conditions were selected by the statistical analysis of the Minitab program(ver.17).

원예치료 프로그램을 위한 중년여성의 반려식물 선호도 조사

김혜린(Hye-Rin Kim), 박화진(Hwa-Jin Park), 이은령(Eun-Ryoung Lee), 제의숙(Eu-Suk Jea) 인간식물환경학회 2023 인간식물환경학회 학술대회 Vol.2023 No.1

Anti-Fibrotic Effect of Urushiol (Rhus Verniciflua Stokes) on Thioacetamide-Induced Liver Fibrosis of Mice Model

( Hyeong Seop Kim ),( Ye Rin Choi ),( Mi Gun Hong ),( Min Jea Shin ),( Sang Jun Yoon ),( Na Young Lee ),( Hyun Ji Ye ),( Sang Hak Han ),( Dong Joon Kim ),( Gi Soo Youn ),( Ki Tae Suk ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1

Aims: Liver fibrosis constitutes a serious problem worldwide due to its rapidly leads to cirrhosis, and even cancer. However, there is no clear medical treatment other than treating the cause. Urushiol has been known to have anti-inflammatory and anti-oxidative effects on various disease. We investigated the effect of urushiol on liver fibrosis induced by thioacetamide (TAA). Methods: Thirty C57BL/6 mice were randomly divided into 3 groups and urushiol was dissolved in vehicle (DMSO) for in vivo experiments: (1) control group; (2) TAA (normal saline as solvent, 300 mg/kg/day, 3 times/week, i.p.) + vehicle (gavage). (3) TAA (300 mg/kg/day, 3 times/week, i.p.) + urushiol (0.128 mg/ mL/day, 28 times, gavage). These groups were analyzed by immunohistochemical staining, reverse transcription polymerase chain reaction, and microarray. Results: The TAA + Urushiol group improved the deposition of fibrillar collagen (Sirius Red (%) 1.55 ± 0.25 vs. TAA, P<0.0001), Fibrosis stage reduced (1.64 ± 0.20 vs. TAA, P<0.0001) and Inflammation activity decreased concurrently (1.17 ± 0.16 vs. TAA, P<0.0001). The analysis of mRNA expression showed that Col1a1 (2.30-fold change vs. TAA, P<0.0001) and TIMP-1 (1.48-fold change vs. TAA, P<0.05), IL-6 (3.03- fold change vs. TAA, P<0.0001), JAK2 (0.89-fold change vs. TAA, P<0.05), STAT3 (3.26-fold change vs. TAA, P<0.0001) downregulated significantly. As shown microarray analysis, downregulation of Col1a1 (1.12-fold change vs. TAA, P<0.05), Chka, lipid metabolic process gene (2.21-fold change vs. TAA, P<0.001), Pnpla3, patatin-like phospholipase domain containing 3 (1.57-fold change, P<0.001) Contrast, Orm2, regulation of immune system process gene (2.28-fold change vs. TAA, P<0.001) Saa1, serum amyloid A (2.25-fold changes vs. TAA, P<0.05), Saa2 (3.09-fold change, P<0.001) Conclusions: Our results indicated that urushiol has therapeutic effect on liver fibrosis. Although it is needed more clinical research, urushiol can be a potential agent for the treatment of liver fibrosis.

Anti-Fibrotic Effects of Gut-Microbiome on Liver

( Na Young Lee ),( Min Jea Shin ),( Gi Soo Youn ),( Sang Jun Yoon ),( Ye Rin Choi ),( Hyeong Seop Kim ),( Dong Joon Kim ),( Sang Hak Han ),( Ki Tae Suk ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1

Aims: Treatment for liver cirrhosis is intended to slow the progression and deterioration of liver function. Although many studies have shown that microbiome is an important factor in improving liver disease progression through the gut-liver axis, the exact mechanism is still unknown. The microbiome in the gut regulates nutrient metabolism and immune response and interacts closely with the host if the gut microbiome can suppress the progression of liver cirrhosis and analyze clinical data. Therefore, our study aim is to suppress the progression of liver fibrosis due to the modulation of gut-microbiome. Methods: Liver cirrhosis in mice was induced by DDC (3,5-diethoxycarboncyl-1,4-dihydrocollidine) diet. 6-week-old male C57BL/6J mice were divided into 5 groups (n=10/group; normal, liver fibrosis-induced control, strain X, L. lactis, and UDCA). Strain X group was given the strain X twice a week [109 CFU/g, 4-week]. Gene expression was compared and analyzed through mRNA sequencing analysis of mouse hepatic stellate cells in the DDC model. Results: The Strain X showed improvement in the Staging level and Sirius red areas compared to the fibrosis group induced by the DDC diet (P<0.05). The levels of the liver fibrosis markers TIMP1 (P=0.02), Col1a (P<0.001), and TGF-ß (P<0.001) were decreased in the Strain X group compared with fibrosis models. When HSCs were isolated, expression of TIMP1 (P=0.38) and Col1a (P=0.055) decreased in strain X. Strain X compared to DDC in the mRNA sequencing, the up-regulated gene is Ecm1, Fos, Serpina1e and the down-regulated gene is Cd5l, Cd63, Marco (P<0.03). Conclusions: Strain X improved fibrosis by modulating the gut microbial composition in a mouse model induced cirrhosis.

Lactobacillus attenuates progression of nonalcoholic fatty liver disease by lowering cholesterol and steatosis

( Na Young Lee ),( Min Jea Shin ),( Gi Soo Youn ),( Sang Jun Yoon ),( Ye Rin Choi ),( Hyeong Seop Kim ),( Haripriya Gupta ),( Sang Hak Han ),( Byoung Kook Kim ),( Do Yup Lee ),( Tae Sik Park ),( Hotai 대한간학회 2021 Clinical and Molecular Hepatology(대한간학회지) Vol.27 No.1

Background/Aims: Nonalcoholic fatty liver disease (NAFLD) is closely related to gut-microbiome. There is a paucity of research on which strains of gut microbiota affect the progression of NAFLD. This study explored the NAFLD-associated microbiome in humans and the role of Lactobacillus in the progression of NAFLD in mice. Methods: The gut microbiome was analyzed via next-generation sequencing in healthy people (n=37) and NAFLD patients with elevated liver enzymes (n=57). Six-week-old male C57BL/6J mice were separated into six groups (n=10 per group; normal, Western, and four Western diet + strains [10⁹ colony-forming units/g for 8 weeks; L. acidophilus, L. fermentum, L. paracasei, and L. plantarum]). Liver/body weight ratio, liver pathology, serum analysis, and metagenomics in the mice were examined. Results: Compared to healthy subjects (1.6±4.3), NAFLD patients showed an elevated Firmicutes/Bacteroidetes ratio (25.0±29.0) and a reduced composition of Akkermansia and L. murinus (P<0.05). In the animal experiment, L. acidophilus group was associated with a significant reduction in liver/body weight ratio (5.5±0.4) compared to the Western group (6.2±0.6) (P<0.05). L. acidophilus (41.0±8.6), L. fermentum (44.3±12.6), and L. plantarum (39.0±7.6) groups showed decreased cholesterol levels compared to the Western group (85.7±8.6) (P<0.05). In comparison of steatosis, L. acidophilus (1.9±0.6), L. plantarum (2.4±0.7), and L. paracasei (2.0±0.9) groups showed significant improvement of steatosis compared to the Western group (2.6±0.5) (P<0.05). Conclusions: Ingestion of Lactobacillus, such as L. acidophilus, L. fermentum, and L. plantarum, ameliorates the progression of nonalcoholic steatosis by lowering cholesterol. The use of Lactobacillus can be considered as a useful strategy for the treatment of NAFLD. (Clin Mol Hepatol 2021;27:110-124)

Openflow & sFlow-based Flows Visualization

Gwan-Woo Kang,Muhammad Afaq,,Jea-Rin KIM,Wang-Cheol Song 중소기업융합학회 2015 중소기업융합학회 국제학술대회논문집 Vol.2 No.1

In Data center network, the overall traffic consists of large flows and small flows which gives rise to bottleneck like situation when small flows are stuck behind large flows. In this paper, we propose an approach by means of which flows in the network can be visualized and eventually can be very easily rescheduled.

Effect of Korean Red Ginseng on metabolic syndrome

Sang Jun Yoon,Seul Ki Kim,Na Young Lee,Ye Rin Choi,Hyeong Seob Kim,Haripriya Gupta,Gi Soo Youn,Hotaik Sung,Min Jea Shin,Ki Tae Suk 고려인삼학회 2021 Journal of Ginseng Research Vol.45 No.3

Metabolic syndrome (MS) refers to a clustering of at least three of the following medical conditions: high blood pressure, abdominal obesity, hyperglycemia, low high-density lipoprotein level, and high serum triglycerides. MS is related to a wide range of diseases which includes obesity, diabetes, insulin resistance, cardiovascular disease, dyslipidemia, or non-alcoholic fatty liver disease. There remains an ongoing need for improved treatment strategies for MS. The most important risk factors are dietary pattern, genetics, old age, lack of exercise, disrupted biology, medication usage, and excessive alcohol consumption, but pathophysiology of MS has not been completely identified. Korean Red Ginseng (KRG) refers to steamed/dried ginseng, traditionally associated with beneficial effects such as anti-inflammation, anti-fatigue, anti-obesity, anti-oxidant, and anti-cancer effects. KRG has been often used in traditional medicine to treat multiple metabolic conditions. This paper summarizes the effects of KRG in MS and related diseases such as obesity, cardiovascular disease, insulin resistance, diabetes, dyslipidemia, or non-alcoholic fatty liver disease based on experimental research and clinical studies.