행인 제제의 독성 및 항암효과와 자연살해세포 활성에 미치는 효과

심범상,최승훈,박재경 대한한방종양학회 2000 대한한방종양학회지 Vol.6 No.1

In this experiment, we examined the the effect of Laetrile Oil to the immune system and tried to disclose the anti-cancer mechanism of this. The result is listed as below. 1. After per-os, sub-cutaneous and into the peritonal injection of Laetrile Oil to the SPF mice, the LD50 is above 5ooomg/kg at even roup. 2. Mean survival days of mice treated with laetril oil, after S-180 cells transplantation into the eritoneal cavoty decreases 1.5 days(-6.8%) compared with the Mean survival days of the control group(22days.) 3. Effects of laetril oil on natural killer cell activity at Effector/Target Cell Ratio with 100:1, 50:1, l0:l into methotrexate-pretreated mice is like this.: Compared with 29.22±l2.7% Cytotoxicity of the control group, sample group's Cytotoxicity had 38.83±l2.5% of meaningful acrease. At l00:1 Effecr/Target Cell Ratio. At 50:l Effector/Target Cell Ratio, control group has 20.02±9.6% Cytotoxiciy and sample group had 3l.53±13.4% Cytotoxicity. At 25:l Effector/Target Cell Ratio, control group has 13.60±6.6% Cytotoxicity and sample group had 20.8l±9.8% Cytotoxicity. According to the above results, the Laetrile Oil represents nontotoxic to a SPF mice. non-effective to transplantable Sarcoma 180 tumors, and activaion in NK cell activity.

The Activation and Developmental Orientation of Appropriate Technology Dissemination for Backward Farming Locality

Jai Sung Shim 한국국제농업개발학회 1989 韓國國際農業開發學會誌 Vol.1 No.2

The CTG repeat polymorphisms of myotonic dystrophy ( DM ) gene in Korean population

(Sung Han Shim),(Youn Hee Cho),(Sung Ro Chung),(Hyung Moon),(Jai Auk Lee),(Yeoun Young Hwang) 대한산부인과학회 1998 춘계학술대회 Vol.- No.-

初生雛 各臟器에 있어서 P^32 및 I^131의 吸收分布

成在基,權宗國,李用斌,沈相七,鄭英彩 서울대학교 1966 서울대학교 論文集 Vol.17 No.-

Radioactive Phosphorus (P^32) and radioactive iodine (I^131) were administered intramuscularlly to the newly hatched chicken in the purpose of determination of the uptake and the distribution, as related to sex and hour differences of the various organs of the bodies. 2 μc of P^32 and I^131 were administered to each chick, and the distribution of P^32 and I^131 were observed in 1 hour and 24 hours after administration. In this experiment forty-four heads of chicken were used (Twenty-two chicken for P^32 and twenty-two chicken for I^131) and the results obtained as follows: 1) The tissues showed an uptake of P^32 dose per 100 milligram of tissue, with the following sequence: Males (1 hour) : hypophysis femur thyroid adrenal testis spleen kidney liver g. mucle brain. (24 hours) : femur testis hypophysis thyroid adrenal kidney liver spleen g. muscle brain. Female (1 hour) : hypophysis femur adrenal ovary liver thyroid spleen kidney g. muscle brain. (24 hour) : hypophysis femur thyroid kidney liver ovary spleen adrenal g. muscle brain. 2) In 1 hour, the uptake of P^32 of the tissues exhibited higher in the males than in the females except the brains. 3) the distribution of P^32 of the tissues exhibited higher in 1 hour than in 24 hours except hypophysis and gastrocnemius mnscles of the females. 4) the tissues showed an uptake of I^131 does per 100 milligram of tissue, with the following sequence: Males (1 hour) : thyroid adrenal hypophysis kidney femur testis g. muscle liver spleen brain. (24 hours) : thyroid adrenal tetis spleen hypophysis kidney femur liver g.muscle brain. Females (1 hour) : thyroid kidney femur adrenal ovary liver hypophysis g.muscle spleen brain. (24 hours) : thyroid hypophysis adrenal ovary kidney spleen femur brain liver g.muscle. 5) The uptake of I^131 of the tissues were highest in the thyroids. 6) The uptake of I^131 of the tissues exhibited higher in 1 hour than in 24 hours except the thyroids.

낙후 농업 지대에 있어서 적정기술보급 활동 및 개발방향

심재성 한국국제농업개발학회 1989 韓國國際農業開發學會誌 Vol.1 No.2

農業生産의 增大와 農村經濟에 미친 影響이 多大하기 때문에 農村開發은 農業生産性을 위한 戰略的 開發의 主된 課題로 算定되어 왔다. 農産的生産地로서의 農村은 國家資源의 큰 몫을 차지하고 있기 때문에 이를 開發하는데 있어서는 農家自體의 立場을 넘어선 國家的 次元의 모든 분야의 機能위에서 考慮되어야 한다. 農業生産性을 向上시키기 위해서는 技術開發뿐만 아니라 開發戰略側面에서의 適正技術普及, 즉 落後農業地帶를 先進開發型 農業地帶로 轉煥시키기 위한 새로운 料學的 知識의 具體化의 先行되어야 한다. 또한 落後地域內에 尙存하고 있는 各種 開發沮害要因을 과감하게 改善할 필요가 있다. 現在 우리나라에서는 農村振興廳 및 農業協同組合이 農業技術의 轉移媒體役割을 하고 있으나 地域性을 달리하는 諸特性을 背景으로 하고 있는 落後地域의 適正技術普及體系는 適切한 補完策의 隨伴이 要請되고 있다. 本 論文에서는 慶北 尙州地方의 落後農業地帶現況을 土臺로 問題點을 導出하여 適正技術普及을 通한 農村開發의 可能性을 摸索하였다.

Mercury(II) Halide and Copper(I) Iodide Complexes of Double-Tweezer Ligand with Thiocyclohexyl End-Group

Jai Young Lee,Sanjina Lee,Minhye Jo,Hayan Lee,박기민,Shim Sung Lee 대한화학회 2009 Bulletin of the Korean Chemical Society Vol.30 No.4

Uncertainty-Limited Turnstile Transport in Deformed Microcavities

Shim, Jeong-Bo,Lee, Sang-Bum,Kim, Sang Wook,Lee, Soo-Young,Yang, Juhee,Moon, Songky,Lee, Jai-Hyung,An, Kyungwon American Physical Society 2008 Physical Review Letters Vol.100 No.17

<P>We present both experimental and theoretical evidence for uncertainty-limited turnstile transport in deformed microcavities. As the degree of cavity deformation was increased, a secondary peak gradually emerged in the far-field emission patterns to form a double-peak structure. Our observation can be explained in terms of the interplay between turnstile transport and its suppression by the quantum mechanical uncertainty principle.</P>

Mechanistic Studies on the Photochemical Degradation of Nifedipine

Shim, Sang-Chul,Pae, Ae-Nim,Lee, Yong-Jai Korean Chemical Society 1988 Bulletin of the Korean Chemical Society Vol.9 No.5

Irradiaton of nifedipine in methylene chloride at 366 nm yielded 2,6-dimethyl-3,5-dicarbomethoxy-4-(2'-nitrosophen yl)-pyridine with the quantum yield 0.37, while irradiation at 254 nm initially gave nitroso compound which in turn is photooxidized to 2,6-dimethyl-3,5-dicarbomethoxy-4-(2'-nitrophenyl) -pyridine with the quantum efficiency of 0.014 on further irradiation in the presence of oxygen. The intramolecular hydrogen abstraction of nifedipine proceeded from the triplet excited sitate.

施肥에 따른 韓國잔디(Zoysia japonica Steud)의 生長 및 主要營業分 含量變化에 關한 硏究

沈載成 培材大學校 1985 論文集 Vol.6 No.-

The effect of fertilizer (or nitrogen) application on the seasonal growth and major nutrients (total nitrogen, total soluble carbohydrate, and total sugar) was studid in Korean lawn grass during a summer-autumn season in field experiments . The results: 1. Maximum dry matter weight of Korean lawn grass was achieved in early August when it was 64.3 g/㎡ with fertilizer and 157.9 g/㎡ with nil fertilizer. On the ether hand the dry matter weight of whole plant including Korean lawn grass reached the maximum in late September, which was late, to some extent, compared with that of piece Korean lawn grass, presumably associated with seed maturing period of C₄type vegetation. 2. There was a large positive effect on dry matter weight in Korean lawn grass by applying fertilizer(NPK) or N-fertilizer. Notable positive effect of fertlizer on leaf (blade) weight in Korean lawn grass was auto detected and the period which its maximum value was obtained coincided with that of dry matter weight of aboveground organs. However, the rate of the weight which formed in the composition of total dry matter was decreased by applying fertilizer. 3, Fertilizer (or N-fertilizer) application increased tiller production and, thus, its maximum reached later than that with nil fertilizer, which mar imply an increased potential of tiller numbers according to fertilizer. A marked effect of N-fertilizer application on the number of tillers was, also, detected when imposing a repeated defoliation practice. 4. In general, the seasonal change pattern of the rhizome of Korean lawn grass coincided with that of the aboveground organs: Its maximum dry matter weight achieved from late August to early September was 194.2 g/㎡ with nil fertlizer,and, with fertilizer, 259.7 g/㎡, of which figures were equivalent to be increased to 33.7 %, compared to that with nil fertilizer. Applying fertilizer increased the weight of root : The highest values were 36.7 g/㎡ with nil fertilizer and 80.9 g/㎡ with fertilizer. 5. Nitrogen contents in the aboveground organs averaged 0.9% with nil N- fertilizer and 1 63% with N-fertilizer. High contents of nitrogen were recorded in June and late autumn Meanwhile, the amount of nitrogen contained in the underground organs with nil N-fertilizer averaged 0.28% in rhizome and 0.25% in root and, thus, there was little difference in the content between two organs. Applying N-fertilizer, however, increased the content of nitrogen to 0.76% in rhizome and 0.46% in root. 6. Total soluble carbohydrate contained in the aboveground organs of Korean lawn grass showed low level in vigorous top growth stage, particularly in July and August. Its contents averaged 13.3% with nil N-fertilizer and 10.4% with N-fertilizer. On the other hand, the average total soluble carbohydrate in rhizome was 26.0%, and 8.2% in root under the condition of nil N-fertilizer. There was a marked fall in response to N-fertilizer in case of rhizome, but no significant decrement was marked in case of root. 7. The content of total sugar in Korean lawn grass averaged 3.1% with nil N- fertilizer and 2.8% with N-fertilizer marking no drastic difference by applying N-fertilizer. Although the content of total sugar was higher·in unders, in which the contents were 4.7% with nil N-fertilizer and 4.7% with N-fertilizer, than in tops , the difference occurred by N-fertilizer application were not apparent. 8. In order to maintain a good looking turf, the problems caused by weed invasion and interactions which may be occurred between fertilizer, weed and Korean lawn grass were discussed.

Xylitol Production by Fermentation

Sang-Yong Kim,Deok-Kun Oh,Suk-Shim Kim,Chul-Jai Kim,Jung-Hoe Kim 한국식품과학회 1996 식품과학과 산업 Vol.29 No.4