강원도 강릉시 강동면에 분포하는 폐탄광으로부터의 배수에 의한 임곡천 및 동해의 오염

허봉,유재영 江原大學校 附設 環境硏究所 1998 環境硏究 Vol.15 No.-

소위 강릉 탄전 지대의 중앙부에 위치한 강원도 강릉시 강동면 지역에는 많은 하천들이 폐탄광으로부터의 산성 광산 배수에 의해 심하게 오염되고 있으며, 그중 임곡천은 그 오염 정도가 가장 심각하다. 임곡천 오염의 주범은 영동 탄광 배수인데, 이로부터 임곡천에 유입되는 오염성분은 Mg, Fe, Al, Si, Ca, Mn,및 SO_(4)등의 용존 주성분들과 Cr, Co, Ni, Cu, Zn, Rb, Sr, Cd, Pb및 U등의 용종 부성분들이다. 이들은 임곡천 Imgok creek is the most severlt polluted one out of the streams which have been being polluted by acid drainages from the abadoned coal mines in the Gangdon-Myeon area, the central part of the so called Gangreung coal field. Imgok creek is being mainly polluted by the draninge from Youngdong coal mine, which supplies such pollutants as Ms, Fe, Al, Si,Ca, Mn, and SO_(4) as major dissolved components and Cr, Co, Ni, Cu, Zn, Rb, Sr, Cd, Pb, and U as minor dissolved components. Agter the influx the pollutnats migrate mainly as dissolved solid, rather than as suspended solids along Imgok creek. The suspended solids in Imgok creek anre very rich in Fe and Al, indicating that they mainy consist of the precipitates of present and past from the polluted water. Most of the dissolved components in the stream waters of imgok creek removed from the aqueous phase by precipitation and dilution before reaching the East Sea, so that water quality of the downstreams of Imgok creek is very similar to that of unplluted tributaries. It suggests that Imgok creek itself is now being severly polluted by the acid drainages from the abandoned cdal minees, but the East Sea is relatively safe from the same pollution The estuart and sea waters around the Goonseon estuary which accepts Imgok creek water certainly show no significant difference in chemical compositons from the mean ocenic water The cottom sediments at the samplin sutes of the sea waters also show no significant trend of their component cariation especially the cariaton of Fe, SO_(4) and Al concentrations These facts again support that the acid mine drainge is not considerablly pollution the East Sea. However , the tributaries supplying the fresh water to the Imgok creek will be certainly polluted by the acid mine draiage as time passes and pollutants will have more chance to migrate in significant amount to the downstream area, which all can be a real threats to the East Sea on the pollution possibility Therefore it is suggested that urgently required are not only water quality and environmental improvement of the severely pollutd Imgok creek but also preparation of the measures on the possible future pollution of the East Sea by the pollution of the same kind

PbZrO₃첨가에 의한 PZT의 입계이동

이호용,김재석,허태무,이종봉 선문대학교 1998 공과대학논문집 Vol.1 No.1

미세연마된 Pb(Zr_(0.52),Ti_(0.48))O_(3)(PZT) 소결체에 PbZrO_(3) 입자들을 뿌리고 900℃에서 1200℃ 사이에서 각각 3시간씩 열처리 하였을 때, 뿌려진 PbZrO_(3) 입자 주위에서 빠른 입자성장과 화학불안정에 의한 입계이동이 일어났다. 1100℃에서는 물결모양의 입자들이 관찰되었고, 1200℃에서는 1100℃?비하여 길쭉하고 큰 입자들이 관찰되었다. 물결모양의 입자들 중에서 입계이동 부위를 조성 분석한 결과 입계이동부위에서 Zr/Ti 비가 약 1.35 정도로 입자 내부보다 높게 나타났다. 이 결과로 PbZrO_(3)가 PZT의 입계를 통하여 확산되면서 입자성장과 화학불안정에 의한 입계이동을 유발하였다는 것을 알 수 있었다. When PbZrO_(3) particles were scattered on polished surfaces of sintered Pb(Zr_(0.52),Ti_(0.48))O_(3) and annealed at temperatures between 900℃ and 1200℃, fast growth of PZT grains and chemically induced grain boundary migration (CIGM) occurred near scattered PbZrO_(3) particles. At 1100℃, corrugated grain boundaries were the most offer observed. In the region swept by a moving grain boundary, Zr/Ti ratio was about 1.35 which is higher than inside PZT grains. This shows that Zr ions diffused along grain boundaries from scattered PbZrO_(3) grains and then CIGM was induced by alloying of Zr in PZT grains

BaTiO₃에서 2차 비정상 입성장

이호용,김재석,허태무,이종봉 선문대학교 1998 공과대학논문집 Vol.1 No.1

Ti-excess BaTiO_(3)를 1360℃와 1370℃ 사이 온도에서 열처리하였을 때, 비정상 입자들이 수 ㎜까지 성장하였다. 이러한 비정상 입자들은 1차 비정상 입성장이 끝난 후에 다시 나타나 이를 2차 비정상 입성장이라고 하였다. 대부분의 2차 비정상 입자들에서 수 십 ㎛ 두께의 (111) 쌍정이 관찰되며, 2차 비정상 입성장은 1360℃와 1370℃ 사이의 온도 범위에서만 일어났다. 이러한 2차 비정상 입성장을 Twin-Plane Re-entrant Edge (TPRE) 성장기구로 설명하였다. When undoped BaTiO_(3) powder of Ti-excess composition was sintered, some abnormal grains appeared and grew to several millimeters at temperatures between 1360℃ and 1370℃. Since it occurred after completion of the first abnormal grain growth, it is called the secondary abnormal grain growth (SAGG). Almost all secondary abnormal grains were observed to contain the (111) double twins of about several tens ㎛ spacing. The SAGG was observed to occur on]y at temperatures between 1360℃ and 1370℃. The SAGG was explained in terms of Twin-Plane Re-entrant Edge (TPRE) growth mechanism.

(65)Pb(Mg1/3Nb2/3)O3-(35)PbTiO3 세라믹스에서 Mg 원료 분말에 따른 분말합성과 미세조직 변화

이호용,이종봉,김재석,허태무 선문대학교 1999 공과대학논문집 Vol.1 No.2

세 가지 다른 MgO 원료 분말(4MgCO_(3) · Mg(OH)_(2) · 4H_(2)O, 초고순도 MgO, 고순도 MgO)을 사용하여 (65)PMN-(35)PT(mol%) 분말을 만들고 분말의 형상 빚 크기, 상형성, 그리고 소결 특성을 조사하였다. 제조한 분말로 성형체를 만들어 1100℃와 1200℃에서 소결 하였을 때, 2차상은 관찰되지 않았고 모두 perovskite 상이었다. 4MgCO_(3) · Mg(OH)_(2) · 4H_(2)O와 초고순도 MgO를 사용한 경우는 소결체의 입자크기가 비슷하였으나, 고순도 MgO 분말을 사용한 경우는 다른 시편들 보다 4배 정도 큰 입자들이 관찰되었다. 이러한 차이는 MgO 분말의 순도와 입자크기, 그리고 원료 분말에서의 Mg 양 차이에서 기인한다고 생각된다. By using three different Mg-source powder (4MgCO_(3) · Mg(OH)_(2) · 4H_(2)O, MgO(very high pure), MgO(high pure)), (65)Pb(Mg_(1/3)Nb_(2/3))O_(3)-(35)PbTiO_(3) (mol%) powder was synthesized. When the three different (65)PMN-(35)PT compacts were respectively sintered at two different temperatures of 1100℃ and 1200℃, other phase except perovskite was not observed. The average grain size in the sample synthesized by using high pure MgO was four times bigger than those in other samples, The difference in grain size among three samples was explained in terms of purity of Mg source powder, particular size, and Mg content in source powder.

비호지킨 림프종의 임상적 고찰

김태원,조은택,조기섭,정재용,허재봉,장영,박유환,정춘해 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

A retrospective clinical and histologic study of 30 non-Hodgkin's lymphomas diagnosed at the Department of Hemato-oncology of the Chosun University from January 1989 to December 1993 is presented. Among total 30 cases whose sexes were mentioned, male were 18 and female were 12 and the ratio is 1.5:1. The peak incidence of non-Hodgkin's lymphoma was found in the third decade. The case distributions by Working formulation were summarized in table 3. The most common histopathologic type of non-Hodgkin's lymphoma was the diffuse large cell type of intermediate grade. The presenting symptoms at the time of first visit to the hospital were summarized in table 4. The most common symptoms were palpable mass. Lymph node enlargements were found in 87 %, and most frequently on cervical area(35%). The incidence of primary nodal lymphoma is more frequent than extranodal lymphoma, 1.2:1. The most common primary site of extranodal lymphoma is the gastrointestinal tract. In the laboratory findings, the data of hemoglobin and hematocrit were summarized in table 8, 9, Values of hemoglobin and hematocrit of female patients greater than those of male patients. The results of the immunophenotypings of nodal and extranodal lymphoma indicates that the B-cell lymphoma are predominant(B:T=1.4:1). The clinical stage was Ⅱ in 9 cases(30%) Ⅲ in 9 cases(30%), Ⅳ in 8 cases(26.7%), Ⅰin 4 cases(13.3%), 28 cases were treated with CHOP regimen. Among them, 17 cases(60.8%) achieved a complete remission. 5 cases had a partial response. The most frequent toxicities were toxic hepatitis.

ShuffleNet Deflection Routing의 경합제어

허재호(Jae-Ho Heo),석정봉(Jung-Bong Suk),이봉영(Bong-Young Lee) 한국정보과학회 1995 한국정보과학회 학술발표논문집 Vol.22 No.2B

본 논문에서는 deflection 방식을 적용한 ShuffleNet의 고정경로 제어방식을 개선하여 성능이 향상된 경합해결 방식들을 제안하고 시뮬레이션을 통해 결과를 분석하였다. 시뮬레이션 결과, 노드의 출력단에서 패킷들이 경합이 할 경우 패킷의 목적지까지 남은 단계 수가 적은 패킷을 우선적으로 보내고 나머지는 deflection 시키는 방식이 전체 deflection 발생율, throughput 및 평균 지연시간 성능특성에서 모두 우수함을 관찰하였다.

ShuffleNet WDM 광통신망의 Deflection Routing 방식에 대한 성능분석

허재호(Jae-Ho Heo),석정봉(Jung-Bong Suk),이봉영(Bong-Young Lee) 한국정보과학회 1994 한국정보과학회 학술발표논문집 Vol.21 No.2B

이 논문에서는 deflection 경로제어 방식을 적용한 ShuffleNet에서 성능에 영향을 주는 topological 요인들을 살펴보고 이러한 요인들을 중심으로 출력버퍼 사용의 효과에 대한 시뮬레이션을 수행하여 성능을 분석하였다. 경로제어 방식은 deflection 방식을 적용하고 트래픽은 uniform 분포를 가정하였다. 성능인자로는 망전체의 throughput, 지연시간으로 하였으며, 트래픽 부하 및 망 크기의 변화에 따른 성능 변화에 대하여 알아보았다. 노드마다 입출력단을 2개씩 상용한 네트웍상에서 버퍼를 무한개 사용하여 얻을 수 있는 최대 throughput을 100%로 보면, 버퍼를 두지 않았을 때는 약 64%-76%를 얻을 수 있었다. 즉 deflection방식의 ShuffleNet에서 버퍼를 하나까지 사용하여도 무한 버퍼를 사용한 경우에 비해 성능이 크게 떨어지지 않음을 알 수 있었다. 또한 동일한 환경에서 패킷이 deflection 되는 비율을 구하였다.

Poster Presentation : The Role of FOXO3a in Decrease of NHEJ (Non-Homologous End Joining) Activity during Cellular Aging of Human Embryonic Fibroblast

( Jee In Heo ),( Jeong Hyun Kim ),( Seong Hoon Park ),( Hong Jun Kang ),( Sung Chan Kim ),( Jae Bong Kim ),( Jae Bong Park ),( Jae Yong Lee ) 한국노년학회 2010 한국노인과학학술단체연합회 국제학술대회 Vol.2010 No.-

Role of FOXO3a in Regulation of DNA Double Strand Break Repair Activity During Aging

Jee-In Heo,Jae-Hyun Kim,Seong-Hoon Park,Hong-Jun Kang,Yoo-Jin Jung,Sung Chan Kim,Jaebong Kim,Jae-Bong Park,Jae-Yong Lee(이재용) 한국실험동물학회 2010 한국실험동물학회 학술발표대회 논문집 Vol.2010 No.2

Non homologous end joining (NHEJ) activity is known to be major double strand break DNA repair acivity in mammals and to be decreased during cellular aging even though their molecular mechanism remains still unknown. NHEJ activity was also decreased in aged tissue of mouse. Caloric restriction rescued decreased NHEJ activity in aged tissued. The level and activity of FOXO3a was also decreased in aged cells and tissues. In order to investigate the relationship between NHEJ activity and FOXO3a in cellular aging, we tested the levels of NHEJ factors and FOXO3a during cellular aging of human embryonic fibroblast (HEF). The protein levels of XRCC4, a NHEJ factor was decreased as well as NHEJ activity and FOXO3a level. To test whether NHEJ activity is dependent on XRCC4 and FOXO3a, we overexpressed XRCC4 and FOXO3a in old HEF by transfecting wildtype expression vector of XRCC4 or FOXO3a. The result showed that NHEJ activity was increased by overexpression of either XRCC4 or FOXO3a. Interestingly, the level of XRCC4 was also increased by overexpression of FOXO3a, suggesting that XRCC4 could be a target gene of FOXO3a. A reporter construct containing XRCC4 promoter and luciferase gene was used to test whether XRCC4 is regulated transcriptionally by FOXO3a. The result showed that luciferase activity was increased by FOXO3a overexpression in old HEF. Further, CHIP assay confirmed that FOXO3a interacts more tightly to XRCC4 promoter in young HEF. Immunohistochemical analysis using FOXO3a in mouse brain showed that aged hippocampus and cortex expressed low level of FOXO3a. Immuno blotting using FOXO3a in mouse brain showed that FOXO3a, XRCC4 and NHEJ were down-regulated in aged tissues. Taken together, the result demonstrated that the XRCC4 is transcriptionally regulated by FOXO3a during aging.

DNA Microarray Analysis of Gene Expression Profiles in Aging process of Mouse Brain

Lee Mi-Suk,Heo Jee-In,Kim Jae-Bong,Park Jae-Bong,Lee Jae-Yang,Han Jeong-A.,Kim Jong-Il Korea Genome Organization 2006 Genomics & informatics Vol.4 No.1

In order to investigate the molecular basis of the aging process in brain, we have employed high-density oligonucleotide microarrays providing data on 10,108 gene clusters to define transcriptional patterns in three brain regions, cerebral cortex, cerebellum, and hippocampus. Comparison of the expression patterns between young (6-week-old) and aged (17-month-old) C57BL/6 male micerevealed that about ten percent (1098) of the genes showed a significant change in the expression level in at least one of the three tissues. Among them, 23 genes were upregulated and 62 genes were downregulated in all three tissues of the old mice. The number of genes upregulated exclusively in hippocampus (337) was much larger compared to other tissues. Gene ontology-based analysis showed the genes related with signal transduction or molecular transports are more likely to be upregulated than downregulated in the aging process of hippocampus. These data may provide some useful means for elucidating the molecular aspect of aging in hippocampus and other regions in brain.