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Robotic-assisted interval cytoreductive surgery in ovarian cancer: a feasibility study
( Semiramis L. Carbajal-mamani ),( David Schweer ),( Merry J. Markham ),( Ashwini K. Esnakula ),( Joseph R. Grajo ),( Jacqueline C. Castagno ),( Joel Cardenas-goicoechea ) 대한산부인과학회 2020 Obstetrics & Gynecology Science Vol.63 No.2
Objective The primary objective was to assess the feasibility of robotic-assisted interval cytoreductive surgery for achieving complete cytoreduction for patients with advanced-stage ovarian cancer. The secondary objective was to examine the perioperative outcomes. Methods A retrospective study of 12 patients with stage ⅢC or Ⅳ ovarian, fallopian tube, and primary peritoneal carcinoma who underwent interval cytoreductive surgery after neo-adjuvant chemotherapy. Results Optimal cytoreduction was achieved in 100% of selected patients. Complete cytoreductive surgery was achieved in 75% of patients. The estimated mean blood loss was 100 mL. The median length of hospital stay was 2 days. Perioperative complication and 30-day readmission rates were 8.3% (1 patient). The median follow-up time was 9.5 months. Conclusion Robotic-assisted interval cytoreductive surgery in ovarian cancer is safe and feasible and may be an alternative to standard laparotomy in selected patients.
( Semiramis L. Carbajal-mamani ),( Merry J. Markham ),( Joaquín Santolaya-forgas ),( Jacqueline C. Castagno ),( Joel Cardenas-goicoechea ) 대한산부인과학회 2020 Obstetrics & Gynecology Science Vol.63 No.2
A 50-year-old non-Hispanic white Caucasian female was diagnosed with breast cancer and was subsequently found to possess the tumorigenic ataxia telangiectasia mutated (ATM) and PALB2 variants but not the BRCA1 and BRCA2 variants. She visited the gynecologic oncology office for routine counseling about risk-reducing salpingo-oophorectomy (RRSO). Although the patient was asymptomatic, an adnexal mass was discovered in the physical examination performed by palpation. Upon using pre-operative imaging techniques, an 8 cm complex adnexal mass was identified. Her CA-125 level was elevated. She underwent complete cytoreductive surgery. Pathological analysis showed a stage IC clear cell carcinoma of the left ovary; subsequently, she received 6 cycles of adjuvant chemotherapy with a combination of carboplatin and paclitaxel. The patient exhibited no signs ovarian cancer in a follow-up appointment after 32 months of treatment. However, bilateral RRSO is not recommended for patients positive for ATM and PALB2. Breast cancer patients with PALB2 and ATM mutations should extensively discuss the risks and benefits of RRSO in light of current data.
이희업(Lee Hee-Up),J. Carbajal,최진유(Choi Jin-Yu) 한국철도학회 2002 한국철도학회 학술발표대회논문집 Vol.- No.-
KTX is going to directly operate on the existing plate girder bridges before the complete construction of new high-speed line. Also the speed and traffic volume is increased after electrification of conventional line. Then, it is necessary to check the dynamic behaviors of these bridges. Therefore, this paper reviews the dynamic behaviors of welded plate girder bridges designed by L-22, a standard load type of KNR. The span lengths of plate girder analyzed here are 6.6m, 9.7m, 12.9m, 16.0m, 19.2m, 22.3m, 25.4m and 31.1m. Using 2-D dynamic analysis, vertical deflection ratios of plate girder and maximum accelerations of car body are calculated. And the analytical results are compared with those of design criteria.
Effects of Dietary Spirulina on Vascular Reactivity
M.A. Juárez-Oropeza,D. Mascher,P.V. Torres-Durán,J.M. Farias,M.C. Paredes-Carbajal 한국식품영양과학회 2009 Journal of medicinal food Vol.12 No.1
There are several reports suggesting that Spirulina (Arthrospira) may have a beneficial effect in the prevention of cardiovascular diseases. Here we review the results of studies on the effects of dietary Spirulina on the vasomotor reactivity of aortic rings excised from either lean or obese Wistar rats. We also review preliminary results on the effects of Spirulina intake on plasma lipids and blood pressure in humans. The results of the former studies strongly suggest that Spirulina induces a tone-related increase in the synthesis/release of nitric oxide by the endothelium as well as an increase in the synthesis/release of a vasodilating cyclooxygenase-dependent metabolite of arachidonic acid and/or a decrease in the synthesis/release of a vasoconstricting eicosanoid by the endothelium. In humans, Spirulina maxima intake decreases blood pressure and plasma lipid concentrations, especially triacylglycerols and low-density lipoprotein-cholesterol, and indirectly modifies the total cholesterol and high-density lipoprotein-cholesterol values.
Effects of Dietary Spirulina on Vascular Reactivity
Juarez-Oropeza, M.A.,Mascher, D.,Torres-Duran, P.V.,Farias, J.M.,Paredes-Carbajal, M.C. The Korean Society of Food Science and Nutrition 2009 Journal of medicinal food Vol.12 No.1
There are several reports suggesting that Spirulina (Arthrospira) may have a beneficial effect in the prevention of cardiovascular diseases. Here we review the results of studies on the effects of dietary Spirulina on the vasomotor reactivity of aortic rings excised from either lean or obese Wistar rats. We also review preliminary results on the effects of Spirulina intake on plasma lipids and blood pressure in humans. The results of the former studies strongly suggest that Spirulina induces a tone-related increase in the synthesis/release of nitric oxide by the endothelium as well as an increase in the synthesis/release of a vasodilating cyclooxygenase-dependent metabolite of arachidonic acid and/or a decrease in the synthesis/release of a vasoconstricting eicosanoid by the endothelium. In humans, Spirulina maxima intake decreases blood pressure and plasma lipid concentrations, especially triacylglycerols and low-density lipoprotein-cholesterol, and indirectly modifies the total cholesterol and high-density lipoprotein-cholesterol values.