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김수관,조세인,이상호 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.1
As the laser becomes more widely available in recent years, the oral and maxillofacial surgeon will have greater opportunity to use it for the treatment of soft tissue and hard tissue pathologies of the mouth. However, little information has been published on the bone. Dental lasers serve as an adjunct to regular treatments and enhancing outcomes in still others. The laser replaces conventional therapies with equal or improved results. Lasers offer new treatment options that heretofore were not available. Laser dentistry is capable of significantly minimizing discomfort, enhancing recovery times, and improving the overall efficiency of the dental office. We describe the basic researches and the developimg laser devices.
구강 연조직 병소의 Nd:YAG laser를 이용한 치료 : 임상 증례보고 CLINICAL CASE REPORTS
김수관,조세인,권병곤,이상호 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.4
The neodymium:yttrium-aluminum-garnet (Nd:YAG) laser is most widely used for treatment of lesions affecting the oral mucosa. A pulsed Nd:YAG laser (SDL-300EN, Samsung Electronics, Korea) with a wavelength of 1.32㎛ was used. In all cases, contact mode was used. Four cases of soft tissue oral lesions are presented to document the clinical aspects. Surgery proceeded without complication and healing was uneventful. This study indicate that the Nd:YAG laser can be used successfully for intraoral soft tissue applications are well tolerated and minimal bleeding.
Shock로 發生한 成人 Respiratory Distress Syndrome
安喜淳,張連珍,金仁世,趙裕永,金晟烈 순천향의과대학 1978 Journal of Soonchunhyang Medical Science Vol.1 No.1
The adult respiratory distress syndnome was originated from acute hemorhagic and septic shock in 3 patients after operation. All patients recovered with active management (PEEP,albumin,diuretics,and steroid) and various intensive therapies. Etio-logical, Pathophysiological and therapeutic points in A.R.D.S. were discussed with review of articles.
소의 대뇌피질로부터 분리된 Synaptosomal Plasma Membrane Vesicle에서의 n - Alkanols의 침투정도
김인세(Inn Se Kim),권재영(Jae Young Kwon),백승완(S 대한통증학회 1993 The Korean Journal of Pain Vol.6 No.2
세포막에서 마취제의 작용점을 규명하기 위하여, 마취제의 많은 부분을 차지하는 n-Alkanol을 이용하여 , 소의 synaptosomal plasma membrane vesicles (SPMV)에서 n-Alkanol의 침투 정도를 형광 probe를 이용한 형광소광법을 통하여 검색하였다. n-Alkanols는 SPMV 외부 단층 (outer monolayer) 의 표면에 주로 분포하되 그 탄소수에 비례하여 소수성 부위에 분포된는 양이 증가되는 경향을 나타 N/A
n - Alkanols 가 cholesterol 과 인지질들로서 제제한 인공세포막에서의 침투정도
김인세(Inn Se Kim),백승완(Seong Wan Baik),정규섭(K 대한통증학회 1993 The Korean Journal of Pain Vol.6 No.1
신선한 소의 대뇌피질로부터 synaptosornal plasma membrane vesicles(SPMV)를 분리하고 이 SPMV로부터 추출한 총지질(cholesterol과 각종 인지질 함유)로서 제제한 인공세포막 (SPMVTL)에서 의 n-alkanols 침투 정도를 형광 probe를 이용한 형광 소광법을 통하여 검색하였다. n-alkanols는 SPMVTL외부 단층 (outer monolayer)의 표면에 주로 분포하되 그 탄소수에 비례하여 소수성 N/A
Hae Kyu Kim,Pyong Ju Kim,Seong Wan Baik,Inn Se Kim,Kyoo Sub Chung Korean Society of Critical Care Medicine 2000 Acute and Critical Care Vol.15 No.2
BACKGROUND: Metabotropic glutamate receptors (mGluRs) participate in the induction of synaptic plasticity phenomena, such as long-term potentiation and long-term depression that are thought to be at the origin of learning and memory. They are also likely to play a role in modulating glutamate-induced neurotoxicity. It will become apparent that mGluRs are excellent targets for the development of drugs that modulate excitatory synaptic transmission. But there were several controversies about the exact role of group 1 mGluRs subtype 5 (mGluR5). This study was designed for evaluation of the neuroprotective role of mGluR5. METHODS: Fifty male Sprague-Dawley rats were divided into three groups, control, MK-801 and lamotrigine. The hippocampus and basal ganglia were removed at 6 hours and 3 days after the one hour transient middle cerebral artery occlusion. The gene expression of mRNA of the brain samples were evaluated by using reverse transcriptase polymerase chain reaction technique. RESULTS: The gene expression of mGluR5 mRNA in hippocampus was increased by 101.96 +/- 18.45% at 6 hours after ischemia and decreased by 50.70 +/- 15.73% at 3 days after ischemia (p
스테로이드 사용(使用)으로 인(因)한 고혈당증(高血糖症)을 동반(同伴)한 대상포진후(帶狀疱疹後) 신경통(神經痛) 환자(患者)의 치험(治驗)
김영추,김해규,백승완,김성수,김인세,정규섭,Kim, Young-Choo,Kim, Hae-Kyu,Baik, Seong-Wan,Kim, Sung-Soo,Kim, Inn-Se,Chung, Kyoo-Sub 대한통증학회 1990 The Korean Journal of Pain Vol.3 No.1
대상포진후 신경통의 치료를 위하여 사용하였던 스테로이드로 인한 고혈당증을 동반한 환자를 치료한 결과를 다음과 같이 요약한다. 첫째, 통증치료실에서 흔히 쓰이는 약물 중에는 고혈당증을 유발하는 것이 많으므로 처치전에 고혈당이 영향을 주는 다른 질환의 유무를 확인하도록 한다. 둘째, 스테로이드 사용으로 인하여 발생되는 일시적인 고혈당중의 경우에는 스테로이드 사용 중단으로 회복이 가능하나 잠재되어 있던 당뇨병의 발현시는 지속적인 당뇨병의 치료를 필요로 한다. 셋째, low level laser therapy는 혈당치에 영향을 미치지 않는 통증치료법으로 유용하게 사용될 수 있다. There are many methods for treatment of post-herpetic neuralgia (PHN) and of these, epidural steroid or intralesional steroid injection is one of the most effective treatments. But there are some problems in the use of steroids. One of which is steroid-induced hyperglycemia. In that case, the treatment of PHN is very difficult and not so effective. So we used the low level laser therapy (LLLT), He-Ne and IR, for the treatment of post-herpetic neuralgia without any changes of blood glucose level. It seemed that LLLT was a very effective method for PHN without any systemic changes.
내시경적 흉부 교감신경절 소작술을 이용한 본태성 다한증의 치료
김영숙,김기엽,김인세 대한마취과학회 1997 Korean Journal of Anesthesiology Vol.33 No.1
Background : Palmar and axillary hyperhidrosis causes important consequences to the social and professional life of the affected patient. Endoscopic thoracic sympathectomy is considered the treatment of choice, because it causes minimal morbidity and high initial success rates. Therefore we used a single-site access technique for primary hyperhidrosis patients. Method : The operation was done under general anesthesia with the patient in a half-sitting position. Through an incision made along the line between lateral ⅓portion of the clavicle and ipsilateral nipple, a Verres needle was introduced below the second rib. About 1.5L of CO2 was insufflated into the pleural cavity. The needle was changed to a 5 mm trochar through which the electroresectoscope was introduced. The heads of the upper 2nd-4th ribs were identified and the sympathetic chain could be seen through the pleura riding over the ribs close to the costovertebral junction. The 2nd-4th ganglia were coagulated and divided down to the periosteum. Finlly the lung was expanded by limiting flow until the airway pressure reach 30∼40 cmH2O. The wound was closed after the removal of electroresectoscope. The procedure was then repeated on the opposite side. Result : There were no postoperative mortality and major complications requring surgical reintervention. The preoperatively wet and cold hands had became warm and dry immediately after operation. All patients were very satisfied. Conclusion : Endoscopic thoracic sympathetic ganglion cauterization is a minimally invasive and highly successful treatment for the patients with primary hyperhidrosis. (Korean J Anesthesiol 1997; 33: 133∼138)
경요도적 전립선 절제술 환자에 있어 혈청전해질 및 삼투질 농도의 변화에 관한 고찰
김해규,정규섭,김인세,성장호 대한마취과학회 1987 Korean Journal of Anesthesiology Vol.20 No.5
Dilutional hyponatremia and serum hypoosmolality are commonly observed during transurethral resection of the prostate in association with the systemic absorption of the irrigating solution. To assess these sequential changes following surgery, 26 patients were studies who underwent transurethral resection of the prostate because of prostatic tumors at Pusan National University Hospital, where 4% Dextrose in Water is Still used as irrigating solution. 0.9% NaCl and furosemide were administered to all 26 patients in the recovery room after surgery. Blood samples were examined for serum electrolytes and osmolality before induction of anesthesia, immediate-postoperatively, and at postoperative 1 hour, 6 hours and 24 hours respectively, The results are as fellows : 1) Of the 26 Patients, 19 Patients shoved abnormalities in serum electrolytes, especially serum sodium, in the immediate postoperative period, while 7 patients showed a slight decrease in serum sodium but within normal limits. Mean changes in serum sodium was 10.9 mEq/l in the immediate postoperative period, but after administration of 0.9% NaCl and furosemide, the level of serum sodium returned to normal limits within 1∼3 hours. Serum calcium decreased approximately 0.8 mg/dl but returned to normal levels 3 hoers after surgery. But no symptoms of hyponatremia or hypocalcemia were not observed. 2) Serum osmolality decreased to about 8.4 mOsm/kg below the preoperative level in accordiance with hyponatremia, but returned to normal levels 24 hours postoperatively. 3) Blood glucose levels increased about 231.5 mg% but returned to normal levels 24 hours postoperatively.