부분 조절 내사시의 근거리각 기준 수술 후 장기간의 경과 관찰

정인영,박영걸,박상우,In Young Jeong,Yeoung Geol Park,Sang Woo Park 대한안과학회 2008 대한안과학회지 Vol.49 No.4

Purpose: To analyze the long-term outcome of near geared standard surgery with full hyperopic correction for partially accommodative esotropia. Methods: The medical records of a total of 24 patients with partially accommodative esotorpia, who had undergone bilateral or unilateral medial rectus recession were retrospectively reviewed. The amount of medial rectus recession was measured based on the near deviation after full hyperopic correction. During the follow-up period the changes of refractive error and angle of deviation were evaluated, and the titmus test and Worth 4-Dot test were performed. Results: The mean ages were 36.63±13.38 months (14~59 months) at the time of wearing glasses and 61.25±25.55 months (25~132 months) at the time of operation. The average follow-up period was 59.67±32.12 months (18~120 months) and preoperative refractive errors were +3.93±1.73 D sph and refractive errors at final visit were +3.64±2.07 D sph (p=0.53). The mean amount of esodeviation were 26.08±8.13PD and 4.25±6.63PD for pre- and post-operatively respectively. Nineteen patients showed postoperative deviation of 10PD or less, one patient was overcorrected, and four patients were undercorrected. Worth 4-Dot test resulted in a fusion response at near and far in one patient preoperatively and in 17 patients postoperatively (p=0.30). A titmus stereotest of less than 100 seconds of arc resulted in 1 of 7 patients and 6 of 14 patients at the time of preoperation and postoperation each (p=0.34). The results were not statistically significant. Four of ten high hyperopic patients (≥ +4.00 diopter) had under- or over-correction (p=0.12), though it was not statistically significant. There were no significant differences in combined conditions. Conclusions: Near geared standard surgery with full hyperopic correction in partially accommodative esotropia patients gave a good surgical result for patients in the mean follow-up duration of 59.67 months.

Interleukin-6 and Tumor Necrosis Factor-α Levels in Tears of Patients With Dry Eye Syndrome

Yoon, Kyung-Chul,Jeong, In-Young,Park, Yeoung-Geol,Yang, Sung-Yeul Lippincott Williams Wilkins, Inc. 2007 Cornea Vol.26 No.4

PURPOSE:: To determine the levels of interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) in tears of patients with dry eye syndrome. METHODS:: IL-6 and TNF-α levels were measured by enzyme-linked immunosorbent assay in tear samples obtained from 18 patients with dry eye (8 patients with Sjögren syndrome and 10 patients with non-Sjögren syndrome) and 14 control subjects. The correlation between IL-6 and TNF-α levels and tear film and ocular surface parameters was analyzed. The relative expression of these cytokines was evaluated in conjunctival impression cytology and conjunctival biopsy specimens by using immunohistochemical staining. RESULTS:: The mean levels of IL-6 and TNF-α were, respectively, 18.57 ± 8.92 and 3.68 ± 3.45 pg/mL in patients with dry eye and 3.59 ± 3.38 (P < 0.01) and < 0.5 (P < 0.01) pg/mL in control subjects. IL-6 level was significantly increased in tears of patients with Sjögren syndrome compared with those with non-Sjögren syndrome (P < 0.01). IL-6 level correlated significantly with tear film breakup time (P = 0.04), Schirmer test (P < 0.01), tear clearance (P = 0.02), keratoepithelioplasty score (P < 0.01), and goblet cell density (P = 0.03), but not with corneal sensitivity (P = 0.08). There was no significant difference in TNF-α level between patients with non-Sjögren and Sjögren syndrome. TNF-α levels did not correlate with tear film and ocular surface parameters. Immunohistochemical staining showed positive staining for IL-6 in specimens from patients with dry eye, especially in specimens from patients with Sjögren syndrome. CONCLUSION:: IL-6 and TNF-α levels are elevated in tears of patients with dry eye syndrome. IL-6 level, but not TNF-α level, is associated with the severity of the disease and correlates with various tear film and ocular surface parameters.

고관절 대치술 환자에서 10% pentastarch 용액이 혈액 요구량에 미치는 영향

류경연,임웅모,정창영,박영걸 최신의학사 1994 最新醫學 Vol.37 No.7

Therapeutic Effect of Umbilical Cord Serum Eyedrops for Persistent Corneal Epithelial Defect

( Kyung Chul Yoon ),( Hwan Heo ),( In Young Jeong ),( Yeoung Geol Park ) 대한안과학회 2005 Korean Journal of Ophthalmology Vol.19 No.3

감염성 각막궤양에 의한 절박천공에서 구조 전층각막이식술의 효과

정인영,유인천,박영걸,윤경철,In-Young Jeong,In-Cheon You,Yeoung-Geol Park,PhD,Kyung Chul Yoon 대한안과학회 2007 대한안과학회지 Vol.48 No.7

Purpose: To investigate the effect of tectonic penetrating keratoplasty for the treatment of impending perforations caused by infectious corneal ulcers. Methods: We analyzed preoperative and postoperative visual acuity, lesion location and size, graft size, postoperative outcome, and complications in 19 patients (19 eyes) with impending perforations due to infectious corneal ulcers. All patients underwent tectonic penetrating keratoplasty and had a minimum follow-up period of 6 months. Results: In our study, eight eyes (42.1%) had herpes simplex keratitis, 6 eyes (31.6%) had bacterial keratitis, and 5 eyes (26.3%) had fungal keratitis. Twelve eyes had a lesion located in the central cornea, while 7 eyes had a lesion located in the paracentral cornea. Visual acuity improved in 13 eyes (68.4%) and anatomical success was achieved in 16 eyes (84.2%). Three eyes (15.8%) developed a graft melting secondary to rejection. Complications included bullous keratopathy (3 eyes, 15.8%), graft infection (3 eyes, 15.8%), neovascularization (2 eyes, 10.5%), and secondary glaucoma (1 eye, 5.3%). Conclusions: Tectonic penetrating keratoplasty maintains ocular integrity and effectively treats impending perforations caused by infectious corneal ulcers.

익상편에서 파이브린 글루를 이용한 자가결막이식술

윤경철,허환,정인영,박영걸,Kyung Chul Yoon,Hwan Heo,In Young Jeong Yeoung Geol Park 대한안과학회 2006 대한안과학회지 Vol.47 No.2

Purpose: To investigate the efficacy of fibrin glue for conjunctival autotransplantation in pterygium. Methods: Forty eyes of 32 patients who underwent conjunctival autotransplantation for primary pterygium with a minimum follow-up period of 6 months were included. Postopertive pain, foreign body sensation, tearing, subconjunctival hemorrhage, surgery time, complication, and recurrence were evaluated prospectively in 20 eyes of 15 patients undergoing surgery with fibrin glue, and in 20 eyes of 17 patients undergoing surgery with sutures. Results: One day postoperative, the scores of pain (P<0.01), foreign body sensation (P<0.01), tearing (P<0.01), and subconjunctival hemorrhage (P=0.01) were significantly lower in the fibrin glue group than in the suture group. One week postoperative, the scores of foreign body sensation (P=0.01) and tearing (P=0.01) were significantly lower in the fibrin glue group than in the suture group. Mean surgery time in the fibrin glue group (18±8 minutes) was significantly shorter than in the sutures group (32±11 minutes) (P<0.01). There was no significant difference in the recurrence rates of the two groups. Conclusions: Use of fibrin glue for conjunctival autotransplantation in pterygium can reduce postoperative discomfort and required surgical time.

Experimental Inhibition of Corneal Neovascularization by Photodynamic Therapy with Verteporfin

Yoon, Kyung-Chul,Ahn, Kyu,Lee, Song,Kim, Kyung,Im, Seong-Kyu,Oh, Han-Jin,Jeong, In-Young,Park, Sang-Woo,Park, Yeoung-Geol,Nah, Hyeon-Ju,Im, Wook-Bin IRL Press 2006 Current eye research Vol.31 No.3

<P>Purpose : To investigate the anti-angiogenic effects of photodynamic therapy with verteporfin in a rabbit model of corneal neovascularization. Methods : One week after suturing, the localization of verteporfin in the neovascularized cornea was examined through fluorescent microscopy 1 hr after administration. Rabbits were treated with one or two times of photodynamic therapy with verteporfin at 1-week intervals. Analysis of corneal neovascularization was performed by biomicroscopic and histological examinations. Results : Fluorescent microscopy showed green fluorescence in the vascular walls and interstitial tissue of the corneal stroma. The mean percentages of neovascularized corneal area at 3 days, 1 week, and 2 weeks after one time of photodynamic therapy were 90.3% ± 3.5%, 71.6% ± 6.2%, and 43.6% ± 15.1% in treated eyes and 96.4% ± 1.9% (p = 0.10), 88.6% ± 4.6% (p = 0.01), and 76.8% ± 4.4% (p</P>