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- 저자 : Hyekyung Noh (검색결과 2 건)
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Hyekyung Noh,Hyunjoo Lee,Seungchul Kim,Jongkil Joo,Dongsoo Suh,Kihyung Kim,Kyusup Lee 대한폐경학회 2019 대한폐경학회지 Vol.25 No.1
Objectives: Body mass index (BMI) is commonly used in epidemiological study or clinical center. However, it is not exactly correlated with body fat composition and does not reflect sex, age, or race. The aim of this article is to evaluate the validity of BMI standards relative to total body fat (TBF) and to estimate new BMI criteria that correspond to TBF for obesity, especially for Asian postmenopausal women. Methods: A total 3,936 patients were included in this cross-sectional study, including 1,565 premenopausal and 2,371 postmenopausal women. At the time of visit, demographic data were collected. We demonstrated the validity of BMI cut-point of 25 kg/m2 by using area under the curve (AUC), and presented the empirical optimal BMI cut-point by using Youden’s index and overall accuracy in both premenopausal and postmenopausal women. Results: BMI-defined obesity (≥ 25 kg/m2) represents high AUC values (> 0.9) for each TBF. In premenopausal women, TBF ≥ 38% and corresponding BMI value was 29.45 kg/m2 indicated the highest both Youden’s index and overall accuracy. In comparison, postmenopausal women who were TBF ≥ 38% showed the highest Youden’s index and overall accuracy, and corresponding BMI value was 26.45 kg/m2. Conclusions: We proposed new BMI criteria for obesity by using TBF reference. With application of bioelectrical impedance analysis, the diagnosis of obesity using BMI criteria may differ between premenopausal and postmenopausal women.
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Case report: secondary infertility after pulmonary tuberculosis treatment
( Sunsuk Kim ),( Jongkil Joo ),( Sieun Han ),( Hyekyung Noh ),( Kyusup Lee ) 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-
The association between pulmonary tuberculosis (TB) and female reproductive health problems is not well addressed. This case show the need to estimate the effect of pulmonary TB on menstrual patterns and fertility of women in childbearing age. The reasons for menstrual abnormalities after TB treatment can be associated with possible antigonadotropic effect of Mycobacterium tuberculosis and increased enzymatic catabolism of estrogen caused by antitubercular drug-rifampicin affecting luteinizing hormone surge. A 32 years old multiparous woman presented to our infertility clinic in April 2015 with two year history of secondary infertility. She had a history of therapeutic termination of pregnancy at 13 weeks gestation by dilatation and evacuation due to multi drug resistance tuberculosis in 2012. And she had induced abortion due to severe hyperemesis gravidarum at 8 weeks gestation in 2010. After tuberculosis medication, she tried for a natural pregnancy for a period of 1 yr with no success. She had been investigated extensively for infertility. Noting had been found except showing polycystic ovary, and two timed intercourses with clomiphene citrates and three intrauterine insemination treatment failed. After this she underwent one cycle of in vitro fertilization (IVF), which resulted in the full-term, normal delivery of a healthy baby at 39 weeks. Any disease which is associated with systemic inflammatory response can change menstral patterns. However, hypomenorrhea, amenorrhea and irregular menstration has been described in a substantial number of patients with pulmonary TB. Acccording to one study, very high (90.9%) incidence of menstrual dysfunction was observed in TB patients which was similar in pulmonary (90.5%) and extrapulmonary (91.7%) TB cases. But the reason for this is poorly understood. TB is still an important cause of mortality and morbidity all over the world. We need to study the association with menstrual dysfunction and pulmonary TB.
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