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- 저자 : Hyekyung Ha (검색결과 59 건)
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Ha, Hyekyung,Lee, Jun Kyoung,Lee, Mee-Young,Lim, Hye-Sun,Shin, Hyeunkyoo The Society of Korean Medicine 2013 대한한의학회지 Vol.34 No.4
Objectives: Galgeun-tang (GGT, gegen-tang, kakkon-to), an herbal formula, is used to treat the common cold, fevers, headaches, hangovers and neck and upper back stiffness. The drugs currently used to treat atopic dermatitis (AD) are limited by the significant adverse effects associated with their long-term usage. The need to efficiently manage the AD response while reducing side effects has led to the development of alternative remedies. Methods: To assess the effects of GGT on AD, the anti-inflammatory and anti-AD properties of GGT were evaluated in both in vitro and in vivo systems. Results: Nitric oxide (NO) and histamine production on lipopolysaccharide (LPS)-treated RAW264.7 cells and phorbol-12 myristate 13-acetate (PMA)/A23187-treated MC/9 cells, respectively, were inhibited by GGT. GGT reduced thymus and activation-regulated chemokine (TARC/CCL17) release on TNF-${\alpha}$/IFN-${\gamma}$ stimulated HaCaT cells in a dose-dependent manner. GGT reduced both plasma levels of IgE and histamine and the dermatitis score in house dust mite induced atopic dermatitis-like lesions on NC/Nga mice. However, there were no significant histopathological differences observed between the GGT group and the AD-induced group, such as AD-like lesions in the dorsal skin or ear or mast cell infiltration in the dorsal skin. Conclusions: These results indicate that GGT inhibits chemokine production by keratinocytes and the atopic dermatitis response in NC/Nga mice, suggesting that GGT may be useful as a therapeutic remedy for treating AD and allergic inflammation-related diseases.
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Ha, Hyekyung,Lee, Hoyoung,Seo, Chang-Seob,Lim, Hye-Sun,Lee, Mee-Young,Lee, Jun Kyoung,Shin, Hyeunkyoo Hindawi Publishing Corporation 2014 Evidence-based Complementary and Alternative Medic Vol.2014 No.-
<P><I>Aims</I>. <I>Artemisia iwayomogi</I> (AI) has been used for fever reduction, diuresis, and hepatoprotection in Korea. The present study was performed to evaluate the anti-inflammatory and antiatopic dermatitis effects of AI using both <I>in vitro</I> and <I>in vivo</I> systems. <I>Methods</I>. The compositions in AI were analyzed by HPLC. To determine the anti-inflammatory effects of AI, the production of nitric oxide (NO) was measured in lipopolysaccharide treated RAW264.7 cells. Histamine levels were assayed to evaluate the antiallergic effects on MC/9 cells stimulated with phorbol-12 myristate 13-acetate and A23187. Finally, AI (10 mg/mouse/day) was topically applied onto the backs and ears of <I>Dermatophagoides farinae</I>-sensitized Nc/Nga mice for four weeks. <I>Results</I>. Isochlorogenic acid A (20.63 ± 0.26 mg/g), chlorogenic acid (9.04 ± 0.08 mg/g), and scopoletin (8.23 ± 0.01 mg/g) were among the major components of AI. AI inhibited the NO and histamine productions in RAW264.7 and MC/9 cells, respectively. In the mice, the topical application of AI reduced the dermatitis scores in the dorsal skin and ears and reduced the plasma levels of IgE. <I>Conclusions</I>. These results suggest that AI might be explored as a potential therapeutic agent to treat AD, and that the analytic method using HPLC will facilitate the development of quality control for AI.</P>
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수변경관 이용 활성화를 위한 자연형 하천 이용행태 및 만족도
하혜경 ( Hyekyung Ha ),서자유 ( Jayoo Seo ) 한국경관학회 2021 한국경관학회지 Vol.13 No.1
본 연구는 하천법 전면 개정 이후 친환경 하천계획 수립에 따라 복원된 자연형 하천을 대상으로 지역민들의 하천 이용행태 및 만족도 조사를 실시하였다. 이는 기존의 하천 자체의 환경과 생태자원에 대한 접근에서 지역민 참여와 프로그램 참여 등 자연형 하천의 수변경관 이용을 활성화하는데 목적이 있다. 연구 방법으로는 자연형 하천 유형에 따라 지역하천, 근린하천, 소하천으로 구분하여 각 하천별로 50명을 대상으로 총 291명 대상의 설문조사를 실시하였다. 연구결과 첫째, 자연형 하천은 지역하천, 근린하천, 소하천 등 하천의 규모와 길이, 고수부지의 상황에 따라 지역민들의 이용행태와 요구사항이 상이하므로 자연형 하천의 수변계획시 하천유형에 따라 구분하여 계획할 필요가 있다. 둘째, 조깅로, 운동공간, 체육시설 등 운동공간이 많은 규모가 큰 하천 일수록 만족도가 높았으며, 활동적인 운동시설에 요구도가 높고, 장시간 이용자가 많으므로 이에 대응하는 조경시설이 요구된다. 셋째, 자연형 하천이 소하천의 경우는 고수부지가 협소하고 수목량과 그늘이 부족하여 휴식시설 등에 대한 요구도가 높게 나타났는데, 추후 소하천의 수변공간에 세심한 계획이 필요하다. 본 연구는 자연형 하천의 수변환경을 개선하기 위한 기초자료로 주민들의 인식조사를 통해 하천 이용행태 및 만족도 조사를 실시함으로써 기존의 자연형 하천 연구가 수질, 수량, 동·식물 환경조사 등 생태환경연구에 치중하였던 것을 한계로 삼아 도심 내에서 자연형 하천의 수변경관 이용을 보다 활성화하기 위한 방안으로 자연형 하천 수변계획시 기초자료로서 의미가 있다. 그러나, 6개의 하천이 전국의 지방하천, 근린하천, 소하천을 대표하기에는 한계가 있으므로 연구 표본을 확대할 필요가 있다. This study conducted a survey on river usage behavior and satisfaction of local residents on natural rivers restored according to the establishment of eco-friendly river plans after the complete revision of the River Law. This aims to revitalize the use of natural rivers, such as local residents’ participation and program participation in access to the environment and ecological resources of the existing river itself. As a research method, according to the type of natural river, it was classified into regional rivers, neighboring rivers, and small rivers, and a total of 291 people were surveyed for 50 people for each river. This study conducted a survey on river usage behavior and satisfaction of local residents on natural rivers restored according to the establishment of eco-friendly river plans after the complete revision of the River Law. This aims to revitalize the use of natural rivers, such as local residents’ participation and program participation in access to the environment and ecological resources of the existing river itself. As a research method, according to the type of natural river, it was classified into regional rivers, neighboring rivers, and small rivers, and a total of 291 people were surveyed for 50 people for each river. As a result of the study, first, natural type rivers are comprehensively conceived such as rivers, waterside land use, and park green areas in the planning stage, but they are separated in the detailed design stage, and the consistency of river and waterfront planning is not maintained. Second, natural type rivers have different usage behaviors and requirements depending on the size and length of rivers such as regional rivers, neighboring rivers, and small rivers, and the situation of the reservoir site, so it is necessary to separate and plan the waterfront plans of natural type rivers. Third, in the case of small rivers of natural type rivers, the demand for rest facilities is high because the high water site is narrow and the amount of trees and shade is insufficient, while the demand for active sports facilities is high in rivers with large river sizes such as neighboring rivers or regional rivers. It is high and there are many users for a long time, so a landscaping facility corresponding to this is required. This study is the basic data for improving the water conversion landscape of natural type rivers, and by conducting a survey on river usage behavior and satisfaction through residents’ perception survey, the existing natural river research is based on ecological environment such as water quality, quantity, animal and plant environment survey. It is a method to further revitalize the watersides of natural rivers within the city, taking the focus on research as a limit, and is meaningful as basic data when planning natural rivers. However, it is necessary to expand the research sample because six rivers are limited to represent local, neighboring and small rivers nationwide.
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이메일 장르 쓰기를 활용한 학문 목적 쓰기 수업 사례 연구
하신영(Shin Young Ha), 이혜경(Hyekyung Lee) 학습자중심교과교육학회 2023 학습자중심교과교육연구 Vol.23 No.9
목적 본 연구에서는 요청 이메일의 장르 관습을 밝히고, 텍스트 외적 관습과 내적 관습을 중심으로 유학생들의 이메일 쓰기 양상을 살펴보고자 한다. 방법 이를 위하여 이메일의 장르 쓰기 교육 모형을 설계하여 두 학기의 수업에 연속적으로 적용하였다. 수업 직후 1차 과제로 교수님께 요청하는 이메일 쓰기를 수행하고, 5주가 경과한 후에는 중간고사에서 유사한 주제로 2차 과제를 수행하도록 하여 수업의 결과를 분석하였다. 분석 기준은 텍스트 외적인 상황 맥락을 적절하게 고려할 수 있는지와 텍스트 자체에 기반한 글의 구조와 내용, 언어 사용 등 텍스트 내적인 관습을 함께 살펴보았다. 결과 수업의 결과 학습자들은 요청 이메일의 구조를 빠트리지 않고 각 구조에 따른 내용도 적절하게 작성하는 모습을 보였지만 요청 이메일의 각 전개 단계에서 사용되는 관습적인 언어 형식에는 오류가 많이 나타났다. 특히 요청하기 기능을 글로써 수행할 때 공손성을 나타내기 위해 사용되는 특정한 문형들과 높임법 사용에 어려움을 보였다. 결론 학습자들은 이메일 장르 쓰기 교육을 통해 이메일의 목적과 수신자와의 관계에 대해 고려하고 사회언어학적인 관습과 규범을 따르는 것의 중요성을 인식할 수 있게 되었다. 또한 장르와 매우 밀접하게 관련된 문법 항목들은 개별적으로 제시할 것이 아니라 장르와 연계하여 제시하는 것이 효과적임을 알 수 있었다. Objectives The purposes of this study were to identify the genre conventions of request e-mails and to analyze the international students’ e-mails based on extra-text conventions and intra-text conventions. Methods We designed a genre-based writing education model of e-mail and applied it to the class. Right after the class, the first task was given to the students to write an requesting e-mail and after 5 weeks, the second task was conducted on a similar topic in the midterm exam to analyze the results of the class. Results Students made few errors in writing appropriate content following the formal structure of the request email. However, there were many sociolinguistic errors in the customary language forms used at each stage of structure. In particular, when performing the function of requesting, it was difficult to use specific sentence patterns and honorifics used to show politeness. Conclusions Through email genre writing education, learners were able to recognize the importance of considering the purpose of email and the relationship with the recipient, and following sociolinguistic conventions and norms. In addition, it was found that it is effective to present grammatical items that are very closely related to the genre, not individually, but in connection with the genre.
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