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The Occurrence of 15-keto-Prostaglandins in the Red Alga Gracilaria verrucosa
Dang, Hung-The,Lee, Hye-Ja,Yoo, Eun-Sook,Hong, Jong-Ki,Choi, Jae-Sue,Jung, Jee-H. 대한약학회 2010 Archives of Pharmacal Research Vol.33 No.9
New 15-keto-prostaglandins (1-4) were isolated from the MeOH extract of the red alga, Gracilaria verrucosa. Their structures were determined to be prostaglandin B congeners (1-3) and a prostaglandin E congener (4) based on the NMR and MS data. Prostaglandins with a C-15 keto function are rare from natural sources. The presence of these metabolites in the alga is notable because 15-keto-prostaglandins (15-keto-PGs) are considered to be the metabolic products of regular prostaglandins in mammals. The occurrence of different prostaglandins in this alga might be due to the existence of different oxidative enzymes, as previously mentioned for oxygenated fatty acids of the red alga Gracilariopsis lemaneiformis. The anti-inflammatory activity of these prostaglandins was examined by evaluating their inhibitory effects on nitric oxide production in lipopolysaccharide (LPS)-activated RAW264.7 murine macrophage cells. These prostaglandins showed weak activity on nitric oxide production.
Hung, Nguyen Dang,Sok, Dai-Eun,Kim, Mee Ree Birkhäuser 2012 Inflammation research Vol.61 No.5
<P>The aim of this study was to examine the inflammation induced by saturated acyl lysophosphatidylcholine (LPC) in vivo and to investigate whether it could be attenuated by the action of polyunsaturated acyl lysophosphatidylcholines (LPCs), which are known as anti-inflammatory lipid mediators.</P>
Effects of Corporate Governance and Earning Quality on Listed Vietnamese Firm Value
DANG, Hung Ngoc,PHAM, Cuong Duc,NGUYEN, Thang Xuan,NGUYEN, Hoa Thi Thanh Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.4
The paper examines the influence of corporate governance (CG) and earning quality (EQ) on corporate value (FV) of Vietnamese enterprises. The study uses GLS regression and linear structure model using data collected from companies listing on the stock market in Vietnam during 2008-2018, with a total of 2,937 observations. The research results indicate that EQ and CG represented by the Integrated Board of Directors and the Integrated Supervisory Board have a positive effect on FV directly and indirectly. The results show that the Integrated Board of Directors has a positive effect on EQ, whereas the Integrated Supervisory Board has a negative effect on EQ. Based on the research results, we suggest that companies need to strictly comply and implement GC, so to bring down the agency cost and consequently to increase performance. The companies also should establish the Board of Director of a proper size, with financial and accounting specialty, and including women board members. The government also needs to improve the management mechanism asking for firms to prepare and publish financial statements with reliable company information, which could be provided to users. These recommendations are a useful basis to help businesses improve FV via changes in the corporate governance factors in each enterprise.
Relationship between Accrual Anomaly and Stock Return: The Case of Vietnam
Hung Ngoc DANG,Dung Manh TRAN 한국유통과학회 2019 The Journal of Asian Finance, Economics and Busine Vol.6 No.4
The study investigates the impact of accrual anomaly on stock return ratio of listed firms in Vietnam. Data were collected from listed firms for the period from 2008 to 2018. To learn about the causes of accrual anomaly in returns and future rate of returns on the Vietnamese stock market, this research is based on accrual analysis of Richardson, Sloan, Soliman, and Tuna (2006) on growth and effective components. We employ GLS regression model for examining the impact of accrual anomaly on stock return ratio and T-test for checking the difference between the lowest and the highest portfolio. The results show that accounting distortion is the main factor impacting the stock return, not growth determinant. Both two determinants of accounting distortion and growth contribute the explanation of the impact of accrual anomaly on profit and future stock return ratio. Experimental evidence confirms an abnormal existence of accrual in the ̣ Vietnam stock market. Aggregate accrual is negatively correlated with future operating profit and future stock return. However, after considering the factors contributing to the impact of future profitability and return on stock returns, the study results show that accounting distortion can account for low sustainability of income that is not growth.
The Impact of Earnings Quality on Firm Value: The Case of Vietnam
DANG, Hung Ngoc,NGUYEN, Thi Thu Cuc,TRAN, Dung Manh Korea Distribution Science Association 2020 The Journal of Asian Finance, Economics and Busine Vol.7 No.3
The study aims to investigate the impact level of earnings quality on firm value. The study has used data with 3,910 observations at listed firms on Vietnam Stock Exchange for the period from 2010 to 2018, and GLS regression analysis is employed in this research. Earnings quality is measured in the aspects of earnings management, earnings persistence, and timeliness of profitability. This study also considers a number of controlled variables that positively influence the firm's value such as firm size, fixed asset investment rate and dividend payout ratio. The results show that earnings quality is positively associated with firm value with having statistical significance. In contrast, some determinants negatively influence firm value such as financial leverage, ratio of market value to book value, and revenue growth. Determinants of firm size, the rate of investment in fixed assets, the rate of dividend payment positively affect the firm value. In contrast, determinants of financial leverage, revenue growth rate and market value to book value ratio are inversely related to firm value according to economic value, Tobin's Q or Price. Based on the findings, some recommendations are proposed for investors, management and policy makers as well in the context of emerging countries including Vietnam.
Connection stiffness reduction analysis in steel bridge via deep CNN and modal experimental data
Hung V. Dang,Mohsin Raza,H. Tran-Ngoc,T. Bui-Tien,Huan X. Nguyen 국제구조공학회 2021 Structural Engineering and Mechanics, An Int'l Jou Vol.77 No.4
This study devises a novel approach, namely quadruple 1D convolutional neural network, for detecting connection stiffness reduction in steel truss bridge structure using experimental and numerical modal data. The method is developed based on expertise in two domains: firstly, in Structural Health Monitoring, the mode shapes and its high-order derivatives, including second, third, and fourth derivatives, are accurate indicators in assessing damages. Secondly, in the Machine Learning literature, the deep convolutional neural networks are able to extract relevant features from input data, then perform classification tasks with high accuracy and reduced time complexity. The efficacy and effectiveness of the present method are supported through an extensive case study with the railway Nam O bridge. It delivers highly accurate results in assessing damage localization and damage severity for single as well as multiple damage scenarios. In addition, the robustness of this method is tested with the presence of white noise reflecting unavoidable uncertainties in signal processing and modeling in reality. The proposed approach is able to provide stable results with data corrupted by noise up to 10%.