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RISS 인기검색어
- 검색키워드
- 저자 : Hong Qiao (검색결과 72 건)
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A new high-order response surface method for structural reliability analysis
Hong-Shuang Li,Zhen-Zhou Lu,Hong-Wei Qiao 국제구조공학회 2010 Structural Engineering and Mechanics, An Int'l Jou Vol.34 No.6
In order to consider high-order effects on the actual limit state function, a new response surface method is proposed for structural reliability analysis by the use of high-order approximation concept in this study. Hermite polynomials are used to determine the highest orders of input random variables, and the sampling points for the determination of highest orders are located on Gaussian points of Gauss-Hermite integration. The cross terms between two random variables, only in case that their corresponding percent contributions to the total variation of limit state function are significant, will be added to the response surface function to improve the approximation accuracy. As a result, significant reduction in computational cost is achieved with this strategy. Due to the addition of cross terms, the additional sampling points, laid on two-dimensional Gaussian points off axis on the plane of two significant variables, are required to determine the coefficients of the approximated limit state function. All available sampling points are employed to construct the final response surface function. Then, Monte Carlo Simulation is carried out on the final approximation response surface function to estimate the failure probability. Due to the use of high order polynomial, the proposed method is more accurate than the traditional second-order or linear response surface method. It also provides much more efficient solutions than the available high-order response surface method with less loss in accuracy. The efficiency and the accuracy of the proposed method compared with those of various response surface methods available are illustrated by five numerical examples.
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The effect of local topography on the seismic response of a coupled train-bridge system
Hong Qiao,Xianting Du,He Xia,Guido De Roeck,Geert Lombaert,Peiheng Long 국제구조공학회 2019 Structural Engineering and Mechanics, An Int'l Jou Vol.69 No.2
The local topography has a significant effect on the characteristics of seismic ground motion. This paper investigates the influence of topographic effects on the seismic response of a train-bridge system. A 3-D finite element model with local absorbing boundary conditions is established for the local site. The time histories of seismic ground motion are converted into equivalent loads on the artificial boundary, to obtain the seismic input at the bridge supports. The analysis of the train-bridge system subjected to multi-support seismic excitations is performed, by applying the displacement time histories of the seismic ground motion to the bridge supports. In a case study considering a bridge with a span of 466 m crossing a valley, the seismic response of the train-bridge system is analyzed. The results show that the local topography and the incident angle of seismic waves have a significant effect on the seismic response of the train-bridge system. Leaving these effects out of consideration may lead to unsafe analysis results.
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A new high-order response surface method for structural reliability analysis
Li, Hong-Shuang,Lu, Zhen-Zhou,Qiao, Hong-Wei Techno-Press 2010 Structural Engineering and Mechanics, An Int'l Jou Vol.34 No.6
In order to consider high-order effects on the actual limit state function, a new response surface method is proposed for structural reliability analysis by the use of high-order approximation concept in this study. Hermite polynomials are used to determine the highest orders of input random variables, and the sampling points for the determination of highest orders are located on Gaussian points of Gauss-Hermite integration. The cross terms between two random variables, only in case that their corresponding percent contributions to the total variation of limit state function are significant, will be added to the response surface function to improve the approximation accuracy. As a result, significant reduction in computational cost is achieved with this strategy. Due to the addition of cross terms, the additional sampling points, laid on two-dimensional Gaussian points off axis on the plane of two significant variables, are required to determine the coefficients of the approximated limit state function. All available sampling points are employed to construct the final response surface function. Then, Monte Carlo Simulation is carried out on the final approximation response surface function to estimate the failure probability. Due to the use of high order polynomial, the proposed method is more accurate than the traditional second-order or linear response surface method. It also provides much more efficient solutions than the available high-order response surface method with less loss in accuracy. The efficiency and the accuracy of the proposed method compared with those of various response surface methods available are illustrated by five numerical examples.
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Qiao, Mu,Lim, Jae-Hong,Ji, Chang-Woo,Chung, Bu-Keun,Kim, Hwang-Yang,Uhm, Ki-Baik,Myung, Cheol-Soo,Cho, Jong-Man,Chon, Tae-Soo 한국응용곤충학회 2008 Journal of Asia-Pacific Entomology Vol. No.
Accurate forecasting of pest density is essential for effective pest management. In this study, a simple Image processing system that automatically estimated the density of whiteflies on sticky traps was developed. The estimated densities of samples in a laboratory and a greenhouse were in accordance with the actual values. The detection system was especially efficient when the whitefly densities were at medium to high levels, however, the development of identification algorithms and more appropriate collection methods may improve the image processing system. Taken together, the results of this study indicate that the image processing system described here may be useful for evaluating the population dynamics.
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A Smart Seat Designed for Crash Safety
Qiao-Chu Cai,Kwang-Hee Lee,Chul-Hee Lee,Chang-Bong Hong 한국자동차공학회 2011 한국자동차공학회 학술대회 및 전시회 Vol.2011 No.11
When the automobile industry has begun, the safety performance is always an important indicator to evaluate the vehicles. As the vehicle industry has developed, many safety devices is invented to protect the passengers of the car, as air bags, sensing systems, head restraints, impact absorbing interior materials, seat belts and so on. In the present work, the smart seat is controlled by a sensor, which is designed to detect the crash and automatically control the seat of the drivers to move back and lay down the backrest of the seat before crash. The actuating system of the seat is composed by electric motors, screw rods driven by the electric motor and connecting devices. With such electromechanical systems, when the crash happens, the driver will keep at a safer gesture and the direct crash to the steer wheel will be avoided. The design concept with computer aided simulation is introduced in the paper. With the performance checked in LS-DYNA with a dummy crash model, the evaluation of the dummy during the back motion of the seat and the crash is conducted.
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( Hong-xu Yang ),( Yue Shang ),( Quan Jin ),( Yan-ling Wu ),( Jian Liu ),( Chun-ying Qiao ),( Zi-ying Zhan ),( Huan Ye ),( Ji-xing Nan ),( Li-hua Lian ) 한국응용약물학회 2020 Biomolecules & Therapeutics(구 응용약물학회지) Vol.28 No.4
In current study, we aimed to investigate whether the gentiopicroside (GPS) derived from Gentiana manshurica Kitagawa could block the progression of alcoholic hepatic steatosis to fibrosis induced by chronic ethanol intake. C57BL/6 mice were fed an ethanol- containing Lieber-DeCarli diet for 4 weeks. LX-2 human hepatic stellate cells were treated with GPS 1 h prior to transforming growth factor-β (TGF-β) stimulation, and murine hepatocyte AML12 cells were pretreated by GPS 1 h prior to ethanol treatment. GPS inhibited the expression of type I collagen (collagen I), α-smooth muscle actin (α-SMA) and tissue inhibitor of metal protease 1 in ethanol-fed mouse livers with mild fibrosis. In addition, the imbalanced lipid metabolism induced by chronic ethanol-feeding was ameliorated by GPS pretreatment, characterized by the modulation of lipid accumulation. Consistently, GPS inhibited the expression of collagen I and α-SMA in LX-2 cells stimulated by TGF-β. Inhibition of lipid synthesis and promotion of oxidation by GPS were also confirmed in ethanol-treated AML12 cells. GPS could prevent hepatic steatosis advancing to the inception of a mild fibrosis caused by chronic alcohol exposure, suggesting GPS might be a promising therapy for targeting the early stage of alcoholic liver disease.
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Modeling of {10-12}-{10-12} secondary twinning in pre-compressed Mg alloy AZ31
Qiao, H.,Guo, X.Q.,Hong, S.G.,Wu, P.D. Elsevier 2017 Journal of alloys and compounds Vol.725 No.-
<P><B>Abstract</B></P> <P>The deformation characteristics of rolled Mg alloy AZ31, which was previously compressed along the rolling direction and then re-compressed along the transverse direction, have been numerically investigated. Secondary/double twinning is allowed in the current EVPSC-TDT model, and {10-12}-{10-12} secondary twinning is found to play an important role in reproducing the experimental data. The deformation behavior of the pre-compressed materials associated with primary and secondary twining has been interpreted in terms of the predicted activities, twin volume fractions and texture evolutions. The {10-12}-{10-12} secondary twinning in the previously twinned region is most active for the 9% pre-compressed material while primary twinning within the residual un-twinned domain dominates twinning behavior for the 3% pre-compressed material.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The EVPSC model is first extended to simulate the {10-12}-{10-12} twinning. </LI> <LI> The deformation behavior of the pre-compressed materials has been interpreted. </LI> <LI> {10-12}-{10-12} twinning plays a key role in reproducing the experimental data. </LI> </UL> </P>
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Pycnogenol attenuates atherosclerosis by regulating lipid metabolism through the TLR4–NF-κB pathway
Hong Luo,Jing Wang,Chenhui Qiao,Ning Ma,Donghai Liu,Weihua Zhang 생화학분자생물학회 2015 Experimental and molecular medicine Vol.47 No.-
Atherosclerosis is a leading cause of death worldwide and is characterized by lipid-laden foam cell formation. Recently,pycnogenol (PYC) has drawn much attention because of its prominent effect on cardiovascular disease (CVD). However, its protective effect against atherosclerosis and the underlying mechanism remains undefined. Here PYC treatment reduced areas of plaque and lipid deposition in atherosclerotic mice, concomitant with decreases in total cholesterol and triglyceride levels and increases in HDL cholesterol levels, indicating a potential antiatherosclerotic effect of PYC through the regulation of lipid levels. Additionally, PYC preconditioning markedly decreased foam cell formation and lipid accumulation in lipopolysaccharide (LPS)-stimulated human THP-1 monocytes. A mechanistic analysis indicated that PYC decreased the lipid-related protein expression of adipose differentiation-related protein (ADRP) and adipocyte lipid-binding protein (ALBP/aP2) in a dose-dependent manner. Further analysis confirmed that PYC attenuated LPS-induced lipid droplet formation via ADRP and ALBP expression through the Toll-like receptor 4 (TLR4) and nuclear factor-κB (NF-κB) pathway, because pretreatment with anti-TLR4 antibody or a specific inhibitor of NF-κB (PDTC) strikingly mitigated the LPS-induced increase in ADRP and ALBP. Together, our results provide insight into the ability of PYC to attenuate bacterial infection-triggered pathological processes associated with atherosclerosis. Thus PYC may be a potential lead compound for the future development of antiatherosclerotic CVD therapy.
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