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      • KCI등재

        ĐÁNH GIÁ KHẢ NĂNG LÀM LÀNH VẾT BỎNG TRÊN CHUỘT CỦA HYDROGEL TỪ AgNP-CHITOSAN-CURCUMIN

        Hoang Ngoc Anh Nhan,Nguyen Ba Trung,Giang Thi Kim Lien,Truong Thi My Phuong,Ho Kha Vinh Nhan,Pham Xuan Anh 한국베트남학회 2023 베트남연구 Vol.21 No.1

        Skin burn is one of the major causes of morbidity and mortality in burn patients due to its susceptibility to infection. The disruption of the epidermal barrier, combined with the denaturation of proteins and lipids, provides a fertile environment that is rich in bacterial nutrients for microbial growth, making it significantly prone to infection. This study aimed to formulate a thermoresponsive hydrogel containing silver nanoparticles (300 ppm), oligo chitosan 2%, and curcumin (0.1%) in the polymer pluronic F127 matrix with a final concentration of 13% to effectively promote the healing of skin wounds. The prepared thermoresponsive hydrogel was investigated for its physical and chemical stability, gelation temperature, and chemical composition. In addition to in vitro antibacterial activity against Staphylococcus aureus found in burn infections, in vivo burn healing and antibacterial activities were also investigated and compared with those of a commercial product using burn-induced infected wounds in mice. The formulation showed antibacterial activity with effective values for wound healing properties, as shown in vivo and by histopathological studies. This study also demonstrates that the thermoresponsive hydrogel was successful as an antibacterial and burned wound-healing transdermal drug delivery system.

      • Geochemical constraints on the spatial distribution of recycled oceanic crust in the mantle source of late Cenozoic basalts, Vietnam

        Hoang, Thi Hong Anh,Choi, Sung Hi,Yu, Yongjae,Pham, Trung Hieu,Nguyen, Kim Hoang,Ryu, Jong-Sik Elsevier 2018 Lithos Vol.296 No.-

        <P><B>Abstract</B></P> <P>This study presents a comprehensive analysis of the major and trace element, mineral, and Sr, Nd, Pb and Mg isotopic compositions of late Cenozoic intraplate basaltic rocks from central and southern Vietnam. The Sr, Nd, and Pb isotopic compositions of these basalts define a tight linear array between Indian mid-ocean-ridge basalt (MORB)-like mantle and enriched mantle type 2 (EM2) components. These basaltic rocks contain low concentrations of CaO (6.4–9.7wt%) and have high Fe/Mn ratios (>60) and FeO/CaO–3MgO/SiO<SUB>2</SUB> values (>0.54), similar to partial melts derived from pyroxenite/eclogite sources. This similarity is also supported by the composition of olivine within these samples, which contains low concentration of Ca and high concentrations of Ni, and shows high Fe/Mn ratios. The basaltic rocks have elevated Dy/Yb ratios that fall within the range of melts derived from garnet lherzolite material, although their Yb contents are much higher than those of modeled melts derived from only garnet lherzolite material and instead plot near the modeled composition of eclogite-derived melts. The Vietnamese basaltic rocks have lighter δ<SUP>26</SUP>Mg values (−0.38±0.06‰) than is expected for the normal mantle (−0.25±0.07‰), and these values decrease with decreasing Hf/Hf* and Ti/Ti* ratios, indicating that these basalts were derived from a source containing carbonate material. On primitive mantle-normalized multi-element variation diagrams, the central Vietnamese basalts are characterized by positive Sr, Eu, and Ba anomalies. These basalts also plot within the pelagic sediment field in PbPb isotopic space. This suggests that the mantle source of the basalts contained both garnet peridotite and recycled oceanic crust. A systematic analysis of variations in geochemical composition in basalts from southern to central Vietnam indicates that the recycled oceanic crust (possibly the paleo-Pacific slab) source material contains varying proportions of gabbro, basalt, and sediment. The basalts from south-central Vietnam (12°N–14°N) may be dominated by the lowest portion of the residual slab that contains rutile-bearing plagioclase-rich gabbroic eclogite, whereas the uppermost portion of the recycled slab, including sediment and basaltic material with small amounts of gabbro, may be a major constituent of the source for the basalts within the central region of Vietnam (14°N–16°N). Finally, the southern region (10°N–12°N) contains basalts sourced mainly from recycled upper oceanic crust that is basalt-rich and contains little or no sediment.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The Vietnam basalts have Sr-Nd-Pb isotopic compositions defining a DMM-EM2 array. </LI> <LI> The mantle source is composed of garnet peridotite and recycled oceanic crust. </LI> <LI> Southern to central Vietnam can be divided into three geochemical mantle domains. </LI> <LI> Their light Mg isotopic compositions are likely inherited from recycled carbonates. </LI> <LI> The volcanism may be produced by Hainan plume, entraining the Paleo-Pacific slab. </LI> </UL> </P>

      • KCI등재

        Adaptive hierarchical sliding mode control using an artificial neural network for a ballbot system with uncertainties

        Hai Le Xuan,Quoc-Dong Hoang,Soon Geul Lee,Dat Pham Xuan,Hoang Tran Viet,Minh Pham Van,Hung Pham Van,Hung Pham Viet,PHAM DUC TUAN,Duc Anh Nguyen 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.2

        Ballbots, which have been studied for over ten years, are under-actuated mobile robots that operate using the inverted pendulum paradigm. Controlling a ballbot poses a number of challenges, including maintaining the stable upright posture from the ground in all directions and making sure it follows the desired trajectory. External factors such as a minor change in contact surface properties or fabrication errors can affect the system's stabilization and transfer capabilities. In this study, an adaptive hierarchical sliding mode control algorithm based on an artificial neural network is developed to make the ballbot robust to external factors. The use of the proposed controller ensures system stability despite uncertainties including friction, accidental centrifugal forces and gravity that occur when the ballbot follows the reference trajectory. The system stability is guaranteed on the basis of Lyapunov theory. Control efficiency and robot stability under system uncertainties are demonstrated by numerical simulation.

      • Potential Impact of Graphic Health Warnings on Cigarette Packages in Reducing Cigarette Demand and Smoking-Related Deaths in Vietnam

        Hoang, Van Minh,Le, Hong Chung,Kim, Bao Giang,Duong, Minh Duc,Nguyen, Duc Hinh,Vu, Quynh Mai,Nguyen, Manh Cuong,Pham, Duc Manh,Ha, Anh Duc,Yang, Jui-Chen Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.no.sup1

        Two years after implementation of the graphic health warning intervention in Vietnam, it is very important to evaluate the intervention's potential impact. The objective of this paper was to predict effects of graphic health warnings on cigarette packages, particularly in reducing cigarette demand and smoking-associated deaths in Vietnam. In this study, a discrete choice experiment (DCE) method was used to evaluate the potential impact of graphic tobacco health warnings on smoking demand. To predict the impact of GHWs on reducing premature deaths associated with smoking, we constructed different static models. We adapted the method developed by University of Toronto, Canada and found that GHWs had statistically significant impact on reducing cigarette demand (up to 10.1% through images of lung damage), resulting in an overall decrease of smoking prevalence in Vietnam. We also found that between 428,417- 646,098 premature deaths would be prevented as a result of the GHW intervention. The potential impact of the GHW labels on reducing premature smoking-associated deaths in Vietnam were shown to be stronger among lower socio-economic groups.

      • Khảo sát ghi chép về mối quan hệ Việt – Trung trong ĐẠI VIỆT SỬ KÝ TOÀN THƯ 大越史記全書 (VIỆT NAM) và MINH THỰC LỤC 明實錄 (TRUNG QUN

        PHAM HOANG QUAN(Ph,mHoà,ngQuâ,n),BUI PHAN ANH THU(Bù,iPhanAnhThư,) 서울여자대학교 인문과학연구소 2011 인문논총 Vol.22 No.-

        베트남과 중국의 역사서에는 동질성을 지닌 사건들에 대한 기록이 많다. 본 논문에서는 베트남의 국학을 대표하는 최초사관들에 의해 만들어진 『大越史記全書』 (대월사기전서) 중에서 중국의 『명실록』에 들어 있는 두 나라의 관계사에 대한 동질적 기록을 발췌하여 서로 비교하였다. 그 결과 『명실록』은 『대월사기전서』에 비해 구체적으로 쓰여 있다는 것을 알 수 있었다. 텍스트의 내용과 그 텍스트의 시대적 배경에 따라 명나라와 대월 간의 외교 관계를 종합적으로 분석하자면 다음과 같은 해석이 가능하다. 첫째, 대월의 호계리가 내란(內亂) 진압을 위한 식량 지원을 해 달라는 명 조정의 요청에 완전히 순종하지 않고 서로 합의하면서 결국 4분의 1만 도와 줬다는 점에서 두 나라의 외교 관계가 평등한 편이라고 볼 수 있다. 둘째로 『대월사기전서』에 들어 있는 5만의 병력과 50마리의 코끼리에 대한 요청은 『명실록』에서 찾을 수 없는 기록이고 식량 수량에 대한 기록도 큰 차이가 난다는 점은 간과할 수 없는 의문점이 된다. 명 조정에서 대국으로써의 체면 때문에 일부러 언급하지 않았는가, 아니면 대월의 사관이 사실보다 지나치게 부풀렸는가에 대한 의문이 생기지 않을 수 없다. 또는 명나라의 사신들이 공무(公務)의 직책을 이용하여 개인적 욕심을 부려서 조정의 뜻에 어긋난 조치라고도 해석할 수 있다. 본문에서 명나라와 대월의 중요한 역사서들의 기록들을 발췌하여 공통점과 차이점을 분석하는 것을 목적으로 삼은 것은, 어느 측이 틀리고 옳다는 판단보다는 사료적 신뢰성을 찾아 베트남과 중국의 외교 관계 성격을 밝히고자 했기 때문이다. 이러한 관점으로 『명실록』과 『대월사기전서』에 나타난 베트남과 중국의 관계사와 전쟁 역사에 대한 많은 공통적 기록들을 발견하게 되었다. 이러한 기록들 간의 차이에 대한 원인은 당시 사관들이 국가주의, 민족주의, 이데올로기, 시대성 등과 같은 요소로부터 지배를 받으면서 사서를 편찬했기 때문일 것이다. 하나의 사건만으로는 명 왕조 시기의 베ㆍ중 관계의 특징을 밝히기는 쉽지 않지만, 본문에서 이러한 시도를 계속해야 동아시아문화권의 ‘문화 교류’의 역사에 대한 연구를 올바르게 할 수 있다는 제의를 하고자 한다. 우선 원천 텍스트 연구에 대해서 한 민족의 역사서인 『대월사기전서』이나 『명실록』의 편찬 과정에 두 나라의 사관들이 민족주의ㆍ국가주의ㆍ정치적 이데올로기ㆍ본국의 정치적 주장 등의 요소들에 영향을 받지 않을 수 없다는 것은 사실이다. 그러므로 이러한 자료들을 가치가 있는 사료로 활용하기 위해서 많은 자료들을 서로 비교하여, 외교적 관계사나 문화 교류의 관계사의 연구 영역을 넓힐 수 있다.

      • KCI등재

        Geochemical constraints on the evolution of the lithospheric mantle beneath central and southern Vietnam

        Hoang Thi Hong Anh,최성희,유용재,Pham Trung Hieu 한국지질과학협의회 2021 Geosciences Journal Vol.25 No.4

        We present comprehensive geochemical and isotopic (Sr-Nd-Hf) datasets for two suites of ultramafic rock in Vietnam, namely xenoliths of spinel lherzolite entrained in late Cenozoic alkali basalts, and Paleozoic ultramafic massifs that occur along the Tam Ky–Phuoc Son suture zone in central and southern Vietnam. The ultramafic massifs are the products of high degrees of melt extraction (up to 40%), and have relatively low equilibrium temperatures of 603 to 778 °C. The lherzolites are residues of relatively low degrees of fractional melting (< 1% up to 20%). The compositions of minerals in the xenoliths reveal that the late Cenozoic lithospheric mantle beneath central and southern Vietnam was hotter (825–1058 °C) than during the Paleozoic. The calculated trace element patterns of metasomatic melts that equilibrated with clinopyroxenes in the LREE-enriched xenoliths show enrichments in Th, U, and LREEs, and depletions in Nb. These data, together with the elevated Ti/Eu ratios of the clinopyroxenes, reflect the role of hydrous silicate melts as the main agents of metasomatism. The ultramafic rocks of the Paleozoic massifs contain spinel with TiO2 contents higher than expected for residual spinel, which suggests the influence of boninitic melt(s). In the lherzolite xenoliths, the clinopyroxenes have MORB-like depleted Sr-Nd-Hf isotopic compositions (87Sr/86Sr = 0.70241–0.70416; εNd = +6.6 to 12.3; εHf = +13.1 to 25.1), suggesting metasomatic melts/fluids from upwelling asthenosphere. We suggest that subduction of the (Paleo-)Pacific Plate and continental collision during the Permian–Triassic played key roles in lithospheric replacement and thinning beneath central and southern Vietnam.

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