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      • KCI등재

        山村綜合開發 事例地域의 經營實態와 發展方向

        郭炅鎬,金世彬 한국산림경제학회 2002 산림경제연구 Vol.10 No.2

        이 연구는 산촌종합개발 사례지역의 경영실태를 파악하고, 산촌발전에 대한 주민인식을 분석하여 산촌 발전방향을 제시하는 데 있다. 경영실태의 특징은 산촌주민들은 오랫동안 한 지역에 거주했으며, 농림업에 종사하는 고령세대였다. 주민들이 토지경영은 0.5ha이상 세대에 의한 토지이용의 집중도가 높지만, 산림자원의 이용도는 낮다. 주민의 소득은 전국평균 농가보다 낮은 수준이며 소득격차가 있다. 산촌주민이 생산시설의 투자 및 소득기반의 관리를 도모하기는 불충분하다. 본 연구결과에 따라 후속대책으로 다음과 같은 점을 고려하여야 할 것이다. 1. 지역특성에 맞는 고용창출 측면에서 농림산물 가공공장을 설립하고, 관광휴양사업 및 육림, 임도 등 산림사업의 전개가 요구되다. 2. 산촌마을 이미지 제고 측면에서 표고, 사과와 같이 브랜드와 독특성 있는 개발이 필요하다. 3. 지역발전 프로그램 수립 측면에서 산촌주민과 지방자치단체가 협력하여 구체화되어야 할 것이다. This study was carried out to examine the management status of Mountain Village Package Development Project Area and to analyze the perception of residents on mountain village development, and then to propose the development direction of mountain village. According to the characteristics of management status, mountain village residents have lived for long time in the same residential district, were occupied in agriculture and forestry, and were composed of the aged households. The land use concentration ratio of over 0.5 ha households was high, and the ratio of forest resource use was low. The income of residents was below that of average farm households. And the investment for production facilities and the management of income foundation were not enough. As the result of this study, the followings must be considered; 1. For the job creation appropriate to regional characteristics, the residents of mountain village were required to establish agroforestry manufacturing factory, expanding to tour-recreation, silviculture, road construction, and so on. 2. For the promotion of mountain village image, it is needed to develop oak mushroom, apple and others as specific brand products. 3. For the settlement of regional development program, it is needed to cooperate residents and local autonomous bodies in mountain village.

      • 관상 동맥 질환에서 아포 E 지단백 유전자 다형성과 혈청 지질치와의 관계

        곽선영,김성구,정호석,이유경,이광희,김철현,최태명,현민수,권영주 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

        Background and aims: The Apolipoprotein E is a ligand of both the protein component LDL receptor as well as the apo E LDL-Receptor related protein (LRP). It modulates the receptor binding of lipoproteins, with the apolipoprotein E found on cell surfaces as its component, thus serving an important role in the lipid metabolism by carrying out the intracellular transport of cholesterol in lipoproteins. The gene for apolipoprotein E is the product of three common genotypes as well as many more rare alleles. The common genotypes are ε2, ε3, and ε4, and are expressed in the three phenotype isoforms of E2, E3, and E4. In the event that E4 is the main component, a rise in the cholesterol level, as the result of down-regulation of the LDL receptor, is observed. Therefore, those samples with E4 genotypes are known to be in much higher risk of coronary artery disease than those with ε3/ε3, while those with ε2 are in low risk (with the exception of hypertiglyceremai Ⅲ). The aim of this study is to analyze in patients with ischemic heart disease the role of aplipoprotein E alleles in order to seek its correlation with coronary artery disease, as well as to seek whether the polymorphism of apo E produces any differences in the severity of coronary artery disease according to plasma lipid levels. Methods: The subjects for study were 273 patients admitted to the Internal Cardiology Division of the Soonchunhyang University Hospital form December 1998 to February 1999. The subjects were divided into the two groups of which one was ischemic heart disease (IHD) experiment group totaling 105 (avg.60.1 years of age, male/female ratio = 69/36) and the control group totaling 168 (avg. 59.7 years of age, male/female = 73:95). The coronary angiogram was given to 127 subjects, and of this total, 94 have developed significant stenosis in the coronary artery. The stages of the analyzing of the apo E phenotype was first, the separation of DNA from the blood samples, subjecting it to the PCR from with 228 base pairs of expanded products were obtained. The band was determined by means of the reverse hybridization principle on the nitrocellulose strip. Results: From the 105 patients the distributions of apo E phenotypes were as follows: ε3/2(5.7%), ε4/2(1.9%), ε3/3(70%), ε4/3(20%), ε4/4(1.9%). The relative frequencies of each allele are as follow: ε2 (0.038), ε3 (0.833), ε4 (0.128). The results show as follows: ⅰ) The IHD experiment group to have a higher occurrence of ε4/3 phenotypes as well as ε4 alleles than the control group. ⅱ) Both the control group and IHD group showed the largest distribution of ε3/3 for phenotypes, and ε4 for alleles. ⅲ) The IHD group showed less ε2/3 phenotypes as well as significantly less allele frequency of ε3 in comparison to the control group. ⅳ) the IHD group showed a much lower level of HDL in comparison to the control group, while the LDL was significantly higher; samples including the apo ε2 showed a significantly higher level of HDL than those without. Among the control group, samples including apo ε2 showed a significantly higher level of TG (triglyceride) than samples without. No significant difference was found between the experiment apo ε4 sample and the control plasma lipid sample. ⅴ) No significant correlation was found between an apo E polynorphism and the number of involved arteries of a coronary angiogram. Conclusion: Between the experiment IHD group and control group were found differences in the frequency of alleles. The polymorphism of apo E alleles may contribute as a risk factor to the development of heart disease by involving itself in the metabolism and modulation of plasma lipids.

      • 한국 대도시 고령자의 체격, 체력 및 운동실태와 운동 프로그램개발에 관한 연구

        김경지,강동원,장주호,전익기,윤우상,곽은창,박영진,유재충 경희대학교 사회체육연구소 1996 體育科學論叢 Vol.- No.9

        The purpose of this study was to investigate the patterns of the health related variables, and physical characteristics and physical fitness of the elderly people in order to provide a exercise program. The data about the health related variables were collected through the personal interview, and the data about physical charateristics and physical fitness (height, weight, % body fat, blood pressure, pulse rate, grip stength, trunk flexion, side step test, 2 min, harvard step test) of 373 elderly people living Seoul and kyungkee area were collected. The conclusions of this study can be summarized as follow; 1. The test results about smoking, drinking, sleeping and self-evaluation of health revealed that the elderly people have self-confidence about their health. 2. Not many elderly people participate the proper exercise program even though they recognize the need of exercise. 3. The results showed that the elderly people do not pay much attention to the intensity of the exercise. 4. Muscle strength training for leg and the lower back and cardio-vascular endurance training was recommended to reduce the risk of varius problems caused by aging. 5. A exercise program was suggested for the elderly people.

      • 림프구에 대한 clozapine의 생체내 유전독성

        임정호,곽경필,김문두,강병조 대한생물치료정신의학회 1997 생물치료정신의학 Vol.3 No.1

        최근 난치성 정신분열증 환자에서 가장 효과적인 약으로 알려진 clozapine은 골수에 작용하여 심각한 부작용인 무과립 구증을 일으킬 수 있다. 무과립구증의 원인 및 기전에 대한 연구는 매우 많으나 현재까지 확실한 결론이 나지 않은 상태이다. 저자들은 clozapine의 이러한 골수 독성에 근거하여 clozapine이 인체내에서 염색체에 어떤 변화를 주는지 아닌지를 알아보기 위해 clozapine 단독치료를 시행한 환자에게서 치료전과 치료중에 얻어진 말초혈액 림프구를 배양하여 염색체에 어떤 변화가 생기는지를 조사하였으나, clozapine에 의한 염색체의 자발적인 변이는 관찰되지 않았다. Objective : Many drugs and environmental chemicals can induce aneuploidy or chromosome instability in vivo or in vitro. Modification of the fidelity of cellular division may occur via a variety of mechanisms and chemical interactions. The clozapine is new antipsychotic drug with superior effect than classic antipsychotics. But, it may produce agranulocytosis and seizure in some patients. Agranulocytosis is a serious side effect of this drug but the cause and mechanism of this side effect is not clearly explained. Some study suggested that oxidative stress can induce chromosome aberration and the other study suggested that clozapine produce free radical and it can induce oxidative stress on some kind of cells. Therefore we decided to investigate whether clozapine and its metabolites can induce genotoxic effect in vivo. Method : The patients were chronic schizophrenic patients without a treatment at least one year. Diagnosis was made by DSM-IV criteria and agreed by both of two psychiatrists. Blood sampling was done before the treatment and during the treatment with considerable time interval. We used peripheral blood lymphocyte culture method and we counted the numerical aberrations, sister chromatid exchanges. Results : Chromosome aberration was not detected in all samples. Conclusion : Clozapine did not induce spontaneous chromosome aberration to human lymphocytes in vivo.

      • 휘안광의 부선특성에 관하여

        박경호,오재현,곽창섭,심원석 연세대학교 산업기술연구소 1980 논문집 Vol.12 No.2

        The authors investigated thoroughly the flotation characteristics of stibnite. The flotation behavior of this mineral was carried out by using modified hallimond tube with various xanthates as a collector and modifying agents such as copper sulphate, lead acetate, sodium sulfide, zinc sulphate, sodium cyanide, sodium sulfite and potassium dichromate. The main results obtained in this experiments are summarized as follows; (1) Stibnite shows that it has maximum floatability in pH range 4.0 to 8.0. (2) Stibnite is activated by copper sulphate and lead acetate. (3) Potassium dichromate is an effective depressing agents in stibnite-xanthate system in pH range 4.0 to 6.0. (4) In the pH range in which the zinc sulphate is preciptated by hydroxide, stibnite is depressed effectively (5) Stibnite is depressed by sodium sulfide in alkaline solution.

      • KCI등재

        진행성 치매와 반복되는 뇌졸중을 보인 뇌 아밀로이드 혈관병증 1예

        유봉구,곽강호,김태유,김광수,유경무 대한치매학회 2004 Dementia and Neurocognitive Disorders Vol.3 No.1

        Cerebral amyloid angiopathy can cause intracerebral hemorrhage, progressive dementia, seizure and transient ischemic attacks. Dementia is a relatively common manifestation and associated with the presence of recurrent strokes and leukoencephalopathy. A 66-year-old right-handed man with hypertension and recurrent strokes presented with rapidly progressive dementia and sudden onset of dysarthria and dizziness. He showed memory impairment, personality and behavioral changes, and executive dysfunction for one and an half years. These symptoms developed insidiously and quite rapidly without fluctuation. Brain CT showed a small hemorrhage in the right cerebellum. Brain MRI, especially gradient-echo images revealed multiple cortical and cortico-subcortical microbleeds. Four weeks later, right hemiparesis suddenly developed and a repeated MRI showed a new left corona radiata infarction. We learn from this case that gradient-echo MR images should be performed in patients with rapidly progressive dementia and recurrent strokes.

      • 休養林 利用客의 特性 및 利用行態에 관한 調査 硏究

        宋亨燮,郭炅鎬 忠南大學校 地域開發硏究所 1993 地域開發論叢 Vol.5 No.-

        Since 1988, Forestry Administration of Korea has established Recreation forests to meet the increasing needs for forest recreation. The purpose of this study is to obtain information on the users’ behaviors and socio-economic characteristics in recreation forest. Respondents were selected 568 adults more than 18 years old randamly from 3 recreation forest of manin, yumyung, and youngchu. Analysis of users’ behaviors and socio-economic characteristics was carried out through frequency and factor analysis methods. The most of noticeable characteristic of users for recreation forest were rather youth groups, high education level, city residents. The major preference activities were walking and climbing in recreation forest. With difference age groups, professional groups, recreation forest site, people tend to have their preference activities differently. According to factor analysis for visit motives three most explanatory factors of visit motives for recreation forest were contact with natural land, life with family, and cultivate mutual friendship.

      • KCI등재

        한국목재산업에 있어 e-Business의 활용

        김세빈,곽경호 충남대학교 농업과학연구소 2003 농업과학연구 Vol.30 No.1

        본 연구는 목재산업의 e-비즈니스 활용실태를 파악하여 목재산업의 e-비즈니스 발전방안을 제시하기 위하여 수행되었다. 한국에 있어 목재산업의 e-비즈니스 활용실태는 고객과의 전자적 연계, 공급업체와의 전자적 연계등 e-비즈니스 사업 환경은 낮은 설정이다. e-비즈니스의 활용 수준은 사내정보 인프라 구축단계로 아직은 도입단계에 걸쳐 있는 것으로 파악되었다. e-비즈니스 활용시 장애요인은 숙련된 인재 부족, e-비즈니스 사업모델의 불충분, e-비즈니스 운영기술/수단의 부족 등으로 나타났다. 따라서 목재산업에 있어 지속적인 e-비즈니스 활용수준을 발전시키기 위하여 다음과 같은 점을 고려하여야 할 것이다. 1. 목재산업의 e-비즈니스 활용을 증진하기 위하여 가격경쟁력, 품질경쟁력과 시장대응능력이 유지되는 사업모델이 모색되어야 할 것이다. 2. 목재산업의 e-비즈니스 모델을 수립하기 위하여, 제품 표준화 체계, DB구축, 전자 카타로그 제작 등 협력업체간 정보 네트워크의 연계가 중요하고, 기업간 아웃소싱 및 타산업과의 제휴를 확대하여 목재산업 경쟁력을 강화시키는 프로그램 개발이 필요하다. 본고에서는 정량적인 자료의 활용에 있어서 다소 부족한 점이 있지만 광의의 목재산업을 주기적으로 조사하여 e-비즈니스 활용 추이를 전망 예측할 수 있는 출발점이 될 수 있다. 향후 연구에 있어 원목생산자, 유통, 합판·보드류, 인테리어재, 악기·가구 등 업종별 e-비즈니스 활용수준을 계량화하고, 업종간 전자적 연계가 가능한 e-비즈니스 활용 모델의 구축과 평가방법 개발이 필요하다. 또한, 국내외 시장 특성과 타 산업과의 연계성을 갖는 글로벌 e-비즈니스 활용 모델을 발굴하고, 소비자 의사를 반영한 e-비즈니스 마케팅기법의 모색이 요구된다. This study was carried out to examine the e-Business status of Korea Forest Product Industries and to propose the development. The use level of e-Business in korea forest product industries have stayed in internal company information network integration stages. But lots of companies located in the insufficient of e-Business models, the lack of qualified staffs, and the shortage of e-Business operating technology and implementation. As the result of this study, the followings must be considered; 1. For the promotion of e-Business use, it is needed to maintain price competitiveness, quality competitiveness, and market correspondence capacity. 2. For the settlement of e-Business models, it is important to connect information network among cooperation companies as like forest products standardize, common database, and standard electronic catalogue. Also, it needed developing program to strengthen the competitiveness of forest product industries, expanding to outsourcing and affiliated companies.

      • β-Difluoro-α-trimethylsilyl-γ-lactam 유도체의 합성

        채규윤,곽경철,문재정,최장호 圓光大學校 基礎自然科學硏究所 2000 基礎科學硏究誌 Vol.18 No.1

        α-위치만 선택적으로 difluoromethylene기가 도입된 α.α-difluoro-γ-trimethylsilyl-γ-lactam 유도체(6)들은 ethyl α.α-difluoro-γ-trimethylsilyl-γ-iodopentanoate(4)는 일차아민 유도체와의 반응으로부터 비교적 편리한 작용조건과 비교적 좋은 수득률로 합성하였다. The target of α.α-difluoro-γ-trimethylsilyl-γ-lactam derivatives(6) with selectively in corporated difluoromethylene on α-position were readily prepared form reaction ethyl α.α-difluoro-γ-trimethylsilyl-γ-iodopentanoate(4) and primary derivatives in moderate yields.

      • KCI등재

        人口學的 특성 屬性에 따른 鷄龍山 國立公園 地域住民의 觀光影響 知覺 差異

        오도교,김세빈,곽경호 충남대학교 농업과학연구소 2006 농업과학연구 Vol.33 No.1

        The purposes of this study were to investigate the influence of local residents' nature environment attitudes for National Park development impact perceptions and to examine application possibility of nature environment attitude for resolution information of National Park management conflicts. Thirty items of residents' perceptions and opinions were designed from previous tourism impact studies. The new environmental paradigm(NEP) was used to measure local residents' nature environment attitudes. In April, 2003. 239 questionnaires were obtained from interview survey in local residents' villages near Gyearyongsan National Park. Generally, most of the local residents perceived low economic effects and negative environment impacts for National Park development. Nature environment attitudes levels were significant differences with socioeconomic variables of local residents, specially high in age, education level and influenced their perceptions toward National Park development impacts. The results were suggested that the nature environment attitudes could be provided a useful reverential framework in resolution of National Park management conflicts.

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