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        Magnetic Resonance Imaging Evaluation of L5–S1 Intervertebral Disc Degeneration in Japanese Women

        Hiroaki Hagiwara,Hirofumi Shibata,Hideya Sakakibara,Tomio Inoue 대한척추외과학회 2014 Asian Spine Journal Vol.8 No.5

        Study Design: Retrospective case series. Purpose: To calculate the prevalence of L5-S1 intervertebral disc degeneration (IDD) by evaluating gynecological disease findings, obtained by pelvic magnetic resonance imaging (MRI), and reveal the risk factors for IDD by analyzing its relationship with age, sacral structure, body mass index (BMI), number of deliveries, and intrapelvic space-occupying lesions. Overview of Literature: Age, obesity, height, smoking history, occupation, and lumbosacral structure are reportedly the main factors of lumbar IDD. However, in women, the relationship of IDD with obstetric and gynecological history is unclear. Methods: The presence of L5–S1 IDD was evaluated on sagittal T2-weighted pelvic MRI during gynecological evaluations in 660 Japanese women. We measured the sacral table angle (STA), sacral kyphosis angle (SKA), and intrapelvic space-occupying lesion size. Age, height, weight, BMI, number of deliveries, lumbosacral structure, size of space-occupying lesions, and presence of uterine leiomyoma based on medical records were compared between the IDD-positive and IDD-negative groups. Results: Lumbosacral IDD was observed in 405 cases (61.4%), and its prevalence increased with age. Differences in age, height, weight, BMI, and number of deliveries between the IDD-positive and -negative groups were significant, but differences in STA, SKA, and presence of uterine leiomyoma and space-occupying lesion size were not. Logistic regression analysis indicated that age, BMI, and STA were risk factors for lumbosacral IDD. Conclusions: Age is the biggest risk factor for lumbosacral IDD in Japanese women, with BMI and STA also contributing to its development. However, SKA and obstetric and gynecological history were not significantly involved.

      • SCISCIESCOPUS

        Crystallographic Texture Development and Its Effect on Corrosion Behavior of Pilgered Zirconium Alloy Tubes

        Choi, Yong,Inoue, Hirofumi The Japan Institute of Metals 2010 MATERIALS TRANSACTIONS Vol.51 No.4

        <P>Crystallographic texture and corrosion of zirconium alloy tube with pilgering were studied. Average grain size of the cross-sectional surface of the tube was changed from 28 μm to 11 μm by 1st pilgering, and to 8 μm by 2nd pilgering. Aspect ratios of the elongated grains on longitudinal surface of as-received, 1st and 2nd pilgered tubes are 1, 6 and 12, respectively. Micro-hardnesses of the tubes are 172, 218 and 246 Hv for their cross sectional surfaces and 180, 233 and 252 Hv for their longitudinal surfaces, respectively. Pilgering results in increasing the (0001) basal and {10\\bar10} prismatic pole densities to TD (tangential direction) split type and AD (axial direction) concentration type, respectively. A preferred orientation is mainly formed by 1st pilgering. Further pilgering produces a texture of (\\bar12\\bar14)[10\\bar10] with a significant spread around [10\\bar10] parallel to AD. Corrosion potential and corrosion rate of the zirconium alloy tubes in dearated aqueous 5% NaCl solution (<I>pH</I>=6.3) at 20°C are in the range of −0.552∼−0.767 V<SUB>SHE</SUB> and 1.88×10<SUP>−7</SUP>∼12.02×10<SUP>−7</SUP> A/cm<SUP>2</SUP>, respectively. Crystallographic anisotropy influences corrosion behavior of the zirconium alloy tubes. Pilgering results in reducing corrosion potential and increasing corrosion rate due to grain size refinement and increased dislocation density rather than crystallographic texture.</P>

      • Crystallographic Texture Change of Pilgered Zirconium Alloy Tubes with Heat Treatment

        Choi, Y.,Inoue, Hirofumi Trans Tech Publications, Ltd. 2007 Materials science forum Vol.558 No.-

        <P>Crystallographic texture of pilgered zirconium alloy tubes was analyzed by neutron diffraction, electron backscatter diffraction (EBSD) and X-ray techniques to study bulk and local texture change with pilgering and heat treatment above re-crystallization temperature. Pilgering resulted in slightly inclining (001) planes to sample normal direction, and aligning effectively (100) planes to the normal of radial direction, respectively. (001) planes of the zirconium tube uniformly exist in radial and tangential directions, however, the (001) planes moved from tangential to radial directions after pilgering followed by heat treatment for 20 hours at 540°C. Some of (001) and (100) planes of pilgered tube were paralleled to longitudinal direction by re-crystallization.</P>

      • KCI등재

        A “Back Light System” for Identification of Sites for Endoscopic Ultrasound-Guided Fine-Needle Aspiration in Solid Pancreatic Masses: A Prospective, Randomized Study with a Crossover Design

        Ryo Harada,Hironari Kato,Soichiro Fushimi,Hirofumi Inoue,Daisuke Uchida,Yutaka Akimoto,Takeshi Tomoda,Kazuyuki Matsumoto,Yasuhiro Noma,Naoki Yamamoto,Shigeru Horiguchi,Koichiro Tsutsumi,Hiroyuki Okada 대한소화기내시경학회 2019 Clinical Endoscopy Vol.52 No.4

        Background/Aims: We applied a back light system (BLS) with a magnifying glass to improve the ability to assess the adequacy ofspecimen sampling using endosonography. We conducted this study to evaluate the effcacy of the BLS in sampling of specimens byendoscopic ultrasound-guided fine needle aspiration of solid pancreatic masses. Methods: This was a prospective, randomized, crossover, single-center clinical trial. An endosonographer evaluated adequacy on grossvisual inspection and identified whitish specimen sampling sites with and without the BLS according to a randomization sequence inthe first and second passes with a 25-G needle. On cytological evaluation, the presence of well-defined pancreatic ductal epithelium wasevaluated by a cytopathologist who was blinded to any clinical information. Results: A total of 80 consecutive patients were eligible during the study period. Adequacy was observed for 52 specimens (65%) withthe BLS and 54 (68%) without the BLS (p=0.88). In assessment of specimen adequacy on gross examination, only fair agreement wasobserved both with and without BLS (kappa score 0.40 and 0.29, respectively). Conclusions: The BLS did not influence the ability to identify specimen sampling sites or reliable assessment of specimen site adequacyusing gross visual inspection.

      • KCI등재

        ORiginal Article : A Novel, Fully Covered Laser-Cut Nitinol Stent with Antimigration Properties for Nonresectable Distal Malignant Biliary Obstruction: A Multicenter Feasibility Study

        ( Hiroyuki Isayama ),( Kazumichi Kawakubo ),( Yousuke Nakai ),( Kouta Inoue ),( Chimyon Gon ),( Saburo Matsubara ),( Hirofumi Kogure ),( Yukiko Ito ),( Takeshi Tsujino ),( Suguru Mizuno ),( Tsuyoshi H The Editorial Office of Gut and Liver 2013 Gut and Liver Vol.7 No.6

        Background/Aims: Stent migration occurs frequently, but the prevention of complications resulting from covered self-expandable metal stents (C-SEMSs) remains unresolved. We prospectively assessed a newly developed C-SEMS, a modi-fied covered Zeo stent (m-CZS), in terms of its antimigration effect. Methods: Between February 2010 and January 2011, an m-CZS was inserted into 42 patients (31 initial drainage cases and 11 reintervention cases) at a tertiary referral center and three affiliated hospitals. The laser-cut stent was flared for 1.5 cm at both ends, with a 1 cm raised bank located 1 cm in from each flared end. The main outcome of this study was the rate of stent migration, and second-ary outcomes were the rate of recurrent biliary obstruction (RBO), the time to RBO, the frequencies of complications, and overall survival. Results: Of the 31 patients with initial drainage, stent migration occurred in four (12.9%, 95% con-fidence interval, 5.1% to 29.0%), with a mean time of 131 days. RBO occurred in 18 (58%), with a median time to RBO of 107 days. Following previous C-SEMS migration, seven of 10 patients (70%) did not experience m-CZS migration until death. Conclusions: m-CZSs with antimigration properties ef-fectively, although not completely, prevented stent migration after stent insertion. (Gut Liver 2013;7:725-730)

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