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      • 논문 : 김수영 산문의 인용 현상에서 표현, 소통, 태도 관련 텍스트 기능과 그 양상

        김흥수 ( Heung Soo Kim ) 국민대학교 어문학연구소 2015 語文學論叢 Vol.34 No.-

        This paper aims to examine the expressive function, the communicative function and the attitude reflecting function of the quotations in the texts of Kim Soo-young`s prose. This study analyzes and discusses various subfunctions of each main function in diverse texts and contexts. A special attention paid on the unique use of Kim Soo-young, the correlation between the textual functions and the modes of quotation. The expressive function realizes cognitive/rhetorical/stylistic functions. The sub-function is reinforcing impression, foregrounding transference of cognitive domain and performing the scene/contextual flow. The communicative function is performing communicative atmosphere and highlighting the communicative process. The sub-function is vitalization of controversy, confirming readers` response and building a dramatic situation. The attitude reflecting function reveals the viewpoint of description for the cognitive, mental and psychological attitude toward the writer himself or the readers. The sub-function represents self-examination, through moderating expression of mental attitude and shift of the viewpoint.

      • KCI등재

        김수영 산문에 나타나는 인용의 화행 관련 텍스트 기능

        김흥수(Heung Soo Kim) 한국어학회 2015 한국어학 Vol.66 No.-

        This paper aims to examine the textual functions which are related to the speech acts of quotations in diverse text types and contexts of Kim Soo-yeong``s Prose. This study deals with the general use of quotations in prose, and with the unique use of quotations in Kim Soo-yeong``s prose. The assertive speech act considered in this paper as the main function of quote is divided into four categories; informative, explanation, claim and criticism. A special attention is paid, for the following sub-functions, on the objectivity of quote, the subjectivity of quoter, the writer``s attitude, the relation between main text and quote, and the modes of quotation. Firstly, the usage of informative consists of objective informative, informative for explanation, and informative for claim and criticism. Secondly, the function of explanation is substitution, development, specification, intensification and explanation accompanying the claim. Thirdly, the function of claim is to explain, set, intensify and make the claim itself. Finally, the function of criticism is presentation, illustration, development and highlighting the process of the dispute. The characteristic usage of claiming and critical functions are to reform the quote in discourse, melt the quote into discourse and interact with the text structure.

      • 김수영과 신동엽 산문의 지시사 표현 양상

        김흥수 ( Heung Soo Kim ) 국민대학교 어문학연구소 2016 語文學論叢 Vol.35 No.-

        This paper aims to examine the expressive/stylistic functions of Kim, Soo-yeong and Shin, Dong-yeop`s prose and find the characteristics of the two writers. In this analysis, the three main results are found. The deictic expressions perform the expressive/stylistic function in connection with discourse/text, based on grammatical/pragmatic function. The deictic expressions reflect the writers``attitude towards the situation and the periodic/social context. The two writers have shown the common ground and differences in the use of deictic expressions. The major points are as follows: The``이``group deictics reflect the writer`s attitude and periodic/social context. The choice of deictics reflect the writer`s cognitive/psychological attitude or distance. Especially, in Kim, Soo-yeong`s prose``저``reflects the negative or distant objects and in some cases point out North Korea. The emphasis related phenomena include repetition, concrete representation, and excessive prenominal construction. The repetition is described as following three features. First, the deictics are repeated as the anaphoric use and the flow of the context. Second, the deictics are represented, facing up a real situation or a situation in context. Simultaneously, the circumstances are generic and untransparent, representation is overlapped, adverbial anaphora ``-게``is being repeated. Third, the deictics is repeated to stress the presence of the object or the content meaning. In repetition, concrete representation, and excessive prenominal construction preferred in Kim, Soo-yeong`s. On the other hand, the emphasis on the identity or the property of the referential objects is preferred in Shin, Dong-yeop`s.

      • HMG-CoA 환원효소 억제제에 의한 ICAM-1 유전자의 발현조절

        김현진,정효균,홍우정,김군순,조영석,김도희,채수흥,구본정,송민호,노흥규,김영건 충남대학교 의과대학 지역사회의학연구소 2001 충남의대잡지 Vol.28 No.1

        Background : ICAM-1 act as one of major adhesion molecules in the atherosclerotic lesion. ICAM-1 expression is mainly regulated at the level of transcription and depend on IFN-γ signal transduction pathway in which the STAT1 transcrption factor is a critical intermediate. IFN-γreceptor not only initiates tyrosine 701 phosphorylation of STAT1 by Jak1 and Jak2, but also phosphorylates serine 727 through the activation of Raf-1/MAP kinases. HMG-CoA reductase inhibitors have anti-atherosclertic effects, beyond normalization of hypercholesterolemia, by directly acting on endothelial cells, macrophages and vascular smooth muscle cells. HMG-CoA reductase inhibitors suppress the synthesis of isoprenoid intermediates such as geranylgeranyl-pyrophosphate or farnesylpyrophosphate. These effects results inhibitors suppress the synthesis of isoprenoid intermediates such as geranylgeranyl-pyrophosphate or farnesylpyrophosphate. These effects results inhibition posttranslational farnesylation and geranyl-geranylation processing of small GTP-binding preoteins and inhibition of normal signaling activities. Method : We made several 5'-deletion constructs of rat ICAM-1 promoter and analyzed the promoter activities by measuring the luciferase activity after transfection into ECV304 cells and smooth muscle cells. We checked the level of total and phosphorylated STAT1 protein by immunoblot analysis using specific antibodies. Results : Lovastatin inhibits IFN-γ-induced ICAM-1 gene expression in the ECV304cell. The cells pretreated with PD98059, MEKK inhibitor showed significantly low ICAM-1 RNA induction with IFN-γ stimulatio. IFN-γ induced phosphorylation of tyrosine 701 was not significantly changed by the pretreatment of lovastatin. But lovastatin suppresses IFN-γ-induced phosphorylation of ERK1/ERK2 which are responsible for the seine 727 phosphorylation in STAT1. Conclusion : We showed that HMG-CoA reductase inhibitors, lovastatin, suppresses IFN-γ mediated ICAM-1 gene expression through the inhibition of transcription. HMG-CoA reductase inhibitor suppresses IFN-γ-induced phosphorylation of serine 727 in STAT1 through the modulation of MAP kinases.

      • KCI등재

        앤더슨 뉴만모형을 이용한 아동의 치과의료이용행태에 영향을 미치는 요인에 관한 연구

        김수남,이흥수,김경회,김대업,박득희 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.1

        The purpose of this study is to provide framework for understanding children's dental utilization. In this paper Andersen-Newman's model is applied to the use of dental visits. This model consists of predisposing, enabling, and need components that describe a person's decision to use dental health services. One thousand, nine hundred seven children and their mothers were selected for the stufy. The children were fourth grade to sixth grade in elementary schools in Iksan city, Korea. Models are operationalized using stepwise multiple regression analysis and path analysis. The number of independent variables used in the anslysis was 39 in total, ie 32 predisposing components, 6 enabling components, and 1 need component. Children's Dental utilization was measured based on the number of visits. The data collceted by means of a questionnaire survey. In this study, the amount of variance by the model was 25 percent. Predisposing factors had the greatest effect on utilization. Number of restricted activity days caused by oral disease, having a regular dental care, and susceptibility on oral disease of children were found to have significant major effects on dental utilization of children. Mother's dental visits was most important factor affecting dental utilization of children.

      • KCI등재

        하악골 절제술후 재이식된 돌결자가골 재이식 : 치험 3례

        김 식,김수관,김운규,김수민,류종희,이준길,조경안,김수흥,정태영,여환호 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.2

        We described three cases of immediate reimplantation of a frozen-thawed autogenous mandible composed of a mixture of iliac bone, marrow, and particulate hydroxyapatite in tumors of the mandible. Acceptable outcomes were obtained in three patients who underwent immediate autogenous mandibular graft reconstruction. The conditions leading to successful outcome of the procedure are also discussed. Reimplantation of frozen autogenous lesioned mandible was performed in three patients with mandibular tumors. Two reimplanted grafts survived without complications following surgery. One case had postoperative infection that resolved with appropriate antibiotic treatment. There were no recurrences of the primary lesions. Satisfactory facial contour after surgery was achieved. These results are most promising, and we believe that, with further refinement, this technique will offer a new and acceptable modality for facial reconstruction in patients with cancer.

      • 김수영 산문에 나타나는 특화 독자 및 특정 독자 표현의 양상

        김흥수 ( Kim Heung-soo ) 국민대학교 어문학연구소 2018 語文學論叢 Vol.37 No.-

        This paper aims to examine the distribution and pragmatic/discourse functions of the referential/vocative expressions for the Characterized Readers and the Specified Readers in Kim Soo-yeong's prose. Careful consideration is given to the unique usage based on general use and diverse uses according to text types or various contexts. A special attention is paid on human/social/cultural relations, communicative functions, the writer’s attitude toward the readers and speech acts. The expressions for the Characterized Readers can be divided in two types: noun phrase with relative clause or noun. They are divided into neutral/positive class, negative class and non-relevant class. The expressions for the positive/negative classes perform speech acts or reflect the writer’s attitude. The expressions for the non-relevant class perform communicative functions. Elliptic expressions ease mental burden and strengthen the message. The expressions for the Specified Readers are used to convey the public message in private situation. They ease the problem of the message and strengthen earnestness.

      • 갑상선 세포에서 전사보조활성인자인 CBP와 CIITA의 인터페론-감마 활성 부위에 대한 조절 : CBP and CIITA on GAS(Interferon- γ Activated Site)-Mediated Transcription in Thyroid Cells

        채수흥,홍우정,김군순,조영석,김도희,김현진,구본정,송민호,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 2001 충남의대잡지 Vol.28 No.1

        Background : In the previous stuides, we identified that the interferon-r activated sequence (GAS) in the 5-flanking region of rat ICAM-1 gene is major element for interferon-r-inducible expression of the gene in rat thyroid cells, FRTL-5. We here, investigated the role of transcriptional coactivators, CBP(CREB binding protein) and CⅡTA (class Ⅱ transactivator) in the modulation of the activity of GAS which could interacts with signal transducers and activators of transcription-1 and 3 (STAT1 and STAT3). Methods : The expression of CBP RNA and protein were quantitated in FRTL-5 after stimulation with interferon-r (IFN-r), thyroid stimulating hormone (TSH), forskolin and methimazole. Direct association of CBP with STAT were analyzed by immunoprecipitation. The transcriptional roles of CBP and CⅡTA in the regulation of GAS were assessed by the cotransfection with their expression vectors with reporters; 5-deletion constructs of rat ICAM-1 promoter or 8xGAS-luc constructs, into FRTL-5 thyroid cells. Results : The level of CBP RNA and protein were not changed by the treatment with TSH, IFN-r, forskolin and methimazole in FRTL-5, FRT and BRL liver cells. The CBP could be directly associated with STAT1. Furthermore, the overexpression of CBP significantly increases the both promoter activities; rat ICAM-1 gene promoter which has GAS element and 8xGAS-luc cassette constructs. However, the cotransfection of CⅡTA decreased the constitutive and CBP-mediated transactivation of rat ICAM-1 promoter and 8xGAS-luc cassette constructs. Conclusion : We identified that the two tanscriptional coactivators; CBP and CⅡTA has differential roles in the regulation of transcriptional activity of GAS drived promoter. CBP increases the GAS activity through the direct binding with STAT1, but CⅡTA inhibited the CBP-mediated transactivation of GAS activity.

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