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      • KCI등재

        A Pilot Study: Association between Minor Physical Anomalies in Childhood and Future Mental Problems

        Helen Cheng,ChengChen Chang,YueCune Chang,WenKuei Lee,RuuFen Tzang 대한신경정신의학회 2014 PSYCHIATRY INVESTIGATION Vol.11 No.3

        Objective-This study aims to investigate association between early recognizable minor physical abnormality (MPA) during childhood is associated with mental health problems in young adults. Methods-In 1984, 169 preschool children in central Taiwan underwent a detailed physical examination for subtle abnormalities (MPA). Fourteen years later, the Brief Symptom Rating Scale (BSRS) and Chinese Health Questionnaire (CHQ) were used to measure specific psychiatric symptoms. Results-There is an association between MPA during childhood and adult characterized with interpersonal sensitivity, anxiety, depression and paranoid mental health symptoms. Conclusion-The signs of childhood MPA can be easily identified and should be regarded as risk factors when predicting mental disorder. Mental health professionals should consider MPAs as important signs for possible development of emotional problems.

      • CONFIGURING PRINCIPAL OPPORTUNISM IN INTERNATIONAL JOINT VENTURE (IJV) PARENTS-IJV RELATIONSHIP: A COMBINATION OF SYMMETRICAL AND ASYMMETRICAL ANALYSIS TO ADVANCE AGENCY THEORY AND RESOURCE DEPENDENCE THEORY TRACK: PRODUCT INNOVATION AND DIFFUSION IN EMERGING MARKETS

        Lu-Yun (Vivian) Cheng,Huifen (Helen) Cai,Zhongqi Jin 글로벌지식마케팅경영학회 2016 Global Marketing Conference Vol.2016 No.7

        The paper addresses the phenomenon of the opportunism that arises from a parent (principal) toward an IJV (agent) and its antecedents. This study integrates Agency Theory and Resource Dependence Theory (RDT) to discover its determinants from the perspectives of principal opportunism. Using Structural Equation Modelling (SEM) techniques and fuzzy-set qualitative comparative analysis (fsQCA) based on a sample of 185 Chinese-foreign IJVs in China, which are useful to reals the overall story of the principal opportunism. This study finds an IJV depends on parents’ support in both knowledge- and property-based resources has more chances to subject to principal opportunism. The result also indicates that psychic distance has a negative impact on principal opportunism. fsQCA, however, provides further solutions that the specific combinations of these predictors or their negation predicts principle opportunism.

      • THE INFLUENCE OF CUSTOMERS RESISTANCE INNOVATION TOWARDS CUSTOMERS ATTRITION BASED ON FSQCA: A CASE STUDY OF SMARTPHONE APP

        Minyi Chen,Yang Sun,Helen (Huifen) Cai,Cheng Hua,Jiaolong Zhang 글로벌지식마케팅경영학회 2018 Global Marketing Conference Vol.2018 No.07

        Introduction The study chooses smartphone applications which have update experience as the study case to analysis if it will cause customer attrition. Application updates aims to make up the bugs which may cause bad effects on using, while in fact, most changes will be resisted by customers. We adapt three elements to collect data about the attitude of customers toward applications update, the conclusion illustrates, customers will resist changes in some conditions and cause customers attrition. Therefore, application developers should focus on the personal emotional reaction and cognitive evolution as well as predict what may influence the customers normal use after the applications update to make correct update decisions. In order to define the relationship between variable and result., we take smartphone application which had experienced update as examples and choose fsQCA as the methodology to analysis. Literature Review Resistance to change is a psychological process, Brehm(1966)claims customers resist to change origins from their believe that they have rights to control free, when this rights be challenged, this resistance behavior will happen due to they want to protect their own rights. Some scholars distinguished the concept of resistance to change: when receptors in the low involvement or limited cognize, their resistance behaviors is likely to be considered as the passive resistance; otherwise, the behaviors would be recognized as active resistance (Nabih,1997). Bagozz and Lee(1999) think that functional barrier is an important factors which influence the degree of innovation receptance, when customers think products after update cannot meet their function needs will cause resistance to change. Resistance always occur passively, bemuse of the disturb of the former habits of using (Ram &Sheth 1989), and former studies also indicate that prejudice towards changes is one of significant factors. Because changes are uncertainty, Fiske and Taylor(1991)claims that uncertainty can make people hate changes and Whitson and Galinsky(2008)consider aversion will be the strong driver of resistance to change to reduce uncertainty and risk. In terms of a company, the cost of maintaining a old customer is much lower than these of develop a new user, Actually, customer attrition is response of entrepreneur revenue and the vital section in development of companies. The famous american honesty management scholar Frederic Reichheld’s research indicates that when the extension of the commercial relationship of entrepreneur and customers, companies can acquire fatter profit through the relationship. Conclusions This study chooses fsQCA as methodology to define the relationship between resistance to change and customer attrition instead of using structural equation modeling. Sometimes, even customers have right cognitive evolution towards changes, when they find their efficiency be influenced by it, they also resist to change; while adverse emotional reaction also has an adverse effect on customer retention though they build positive cognitive evolution about changes. there is a remain circumstance of lossing of customers that when customers hate changes and they find their efficiency be influenced by update, the honesty of this product will also decrease. This three condition all contribute to customers attrition which should be paid more attention by companies.

      • KCI등재

        Pemetrexed Continuation Maintenance in Patients with Nonsquamous Non-small Cell Lung Cancer: Review of Two East Asian Trials in Reference to PARAMOUNT

        James Chin-Hsin Yang,안명주,Kazuhiko Nakagawa,Tomohide Tamura,Helen Barraclough,Sotaro Enatsu,Rebecca Cheng,Mauro Orlando 대한암학회 2015 Cancer Research and Treatment Vol.47 No.3

        Purpose A recent phase III study (PARAMOUNT) demonstrated that pemetrexed continuation maintenance therapy is a new treatment paradigm for advanced nonsquamous non-small cell lung cancer (NSCLC). The majority of patients enrolled in PARAMOUNT were Caucasian (94%). We reviewed efficacy and safety data from two clinical trials, which enrolled East Asian (EA) patients, to supplement data from PARAMOUNT on pemetrexed continuation maintenance therapy in patients with nonsquamous NSCLC. Materials and Methods Study S110 was a phase II, multicenter, randomized, controlled, open-label trial in never-smoker, chemonaïve, EA patients (n=31) with locally advanced or metastatic nonsquamous NSCLC (n=27). Study JMII was a multicenter, open-label, single-arm, postmarketing, clinical trial in Japanese patients (n=109) with advanced nonsquamous NSCLC. PARAMOUNT was a multicenter, randomized, double-blind, placebo-controlled trial in patients with advanced nonsquamous NSCLC. Results In EA patients with nonsquamous NSCLC, the median progression-free survival (PFS) for pemetrexed continuation maintenance therapy was 4.04 months (95% confidence interval [CI], 3.22 to 5.29 months) in study S110 and 3.9 months (95% CI, 3.2 to 5.2 months) in study JMII. The median PFS for pemetrexed continuation maintenance therapy in PARAMOUNT was 4.1 months (95% CI, 3.2 to 4.6 months). Pemetrexed continuation maintenance therapy in EA patients in studies S110 and JMII did not lead to any unexpected safety events, and was consistent with PARAMOUNT’s safety profile. Conclusion The efficacy and safety data in the EA trials were similar to those in PARAMOUNT despite differences in patient populations and study designs. These data represent consistent evidence for pemetrexed continuation maintenance therapy in EA patients with advanced nonsquamous NSCLC.

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