http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Haruka Nishimura,Kazuyasu Sugiyama,Yoshinobu Tsujimoto,Hajime Koyama 한국유체기계학회 2018 International journal of fluid machinery and syste Vol.11 No.3
The rotordynamic fluid forces on a columnar rotor modeling the front shroud of Francis turbine caused by the leakage flow and whirling motion are evaluated by the experiments and the computations, to explain the self-excited vibration observed in free vibration tests. In addition to the leakage flow models previously proposed, a new model is proposed to include the effects of the rotation and whirling motion of the rotor to evaluate the rotordynamic fluid forces. After checking the validity of the models by comparisons with experiments and CFD, the characters of each component are discussed based on the physical mechanism producing the forces. It was found that the rotordynamic force component normal to the whirling orbit is mainly caused by the centrifugal forces of the added mass of the fluid in the clearance and that the tangential force is mainly caused by the acceleration of the axial leakage flow through the clearance.
A case of autoimmune enteropathy with CTLA4 haploinsufficiency
( Haruka Miyazaki ),( Namiko Hoshi ),( Michitaka Kohashi ),( Eri Tokunaga ),( Yuna Ku ),( Haruka Takenaka ),( Makoto Ooi ),( Nobuyuki Yamamoto ),( Suguru Uemura ),( Noriyuki Nishimura ),( Kazumoto Iij 대한장연구학회 2022 Intestinal Research Vol.20 No.1
Autoimmune enteropathy (AIE) is a rare disease, characterized by intractable diarrhea, villous atrophy of the small intestine, and the presence of circulating anti-enterocyte autoantibodies. Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome, and mutations in FOXP3, which is a master gene of regulatory T cells (Tregs), are major causes of AIE. Recent studies have demonstrated that mutations in other Treg-associated genes, such as CD25 and CTLA4, show an IPEX-like phenotype. We present the case of a 13-year-old girl with CTLA4 haploinsufficiency, suffering from recurrent immune thrombocytopenic purpura and intractable diarrhea. We detected an autoantibody to the AIE-related 75 kDa antigen (AIE-75), a hallmark of the IPEX syndrome, in her serum. She responded well to a medium dose of prednisolone and a controlled dose of 6-mercaptopurine (6-MP), even after the cessation of prednisolone administration. Serum levels of the soluble interleukin-2 receptor and immunoglobulin G (IgG) were useful in monitoring disease activity during 6-MP therapy. In conclusion, autoimmune-mediated mechanisms, similar to the IPEX syndrome, may be involved in the development of enteropathy in CTLA4 haploinsufficiency. Treatment with 6-MP and monitoring of disease activity using serum levels of soluble interleukin-2 receptor and IgG is suggested for such cases. (Intest Res 2022;20:144-149)
Kazutoshi Hamada,Kazuhiko Shimasaki,Yasuyo Nishimura,Haruka Egawa,Katsuhira Yoshida 한국원예학회 2009 Horticulture, Environment, and Biotechnology Vol.50 No.4
We examined the effects of spectral composition conversion films on proliferation of protocorm-like body (PLB) of Cymbidium finlaysonianum. In this study, several red fluorescent films (NB-PS, BD-PS, CD-PC and ID-PS) were used for culture. These films, which developed by our group, have different characteristics on the pattern of absorption and emission spectra of the light. PLBs were cultured under transmitted light from these films provided from cool fluorescent light with 16h photoperiod for 40 days. Blank film (transparent PS film) was covered as the control. NB-PS and BD-PS films increased significantly the number of PLB after 20 days of culture. However, the number of PLB covered with ID-PS and CD-PC film was almost similar to blank film throughout the culture. At 40 days after culture, the increase of number of PLB was as follows; BD-PS>NB-PS>CD-PC>ID-PS>Blank. Also, NB-PS and BD-PS film increased significantly the normal PLBs. In addition, the number of PLB was almost similar regardless the period of the NB-PS film-covered time. These results showed that the proliferation of Cymbidium PLB would be controlled accurately by a delicate difference of the wavelength distribution of the light. We found that the red fluorescent films (NB-PS and BD-PS) increased the PLB proliferation of C. finlaysonianum, even if the film was covered only during early stage of the culture.