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Lee, Beom Seok,Lee, Yang Ui,Kim, Han-Sang,Kim, Tae-Hyeong,Park, Jiwoon,Lee, Jeong-Gun,Kim, Jintae,Kim, Hanshin,Lee, Wee Gyo,Cho, Yoon-Kyoung Royal Society of Chemistry 2011 Lab on a chip Vol.11 No.1
<P>We report a fully integrated device that can perform both multiple biochemical analysis and sandwich type immunoassay simultaneously on a disc. The whole blood is applied directly to the disposable “lab-on-a-disc” containing different kinds of freeze-dried reagents for the blood chemistry analysis as well as reagents required for the immunoassay. The concentrations of different kinds of analytes are reported within 22 min by simply inserting a disc to a portable device. Using the innovative laser irradiated ferrowax microvalves together with the centrifugal microfluidics, the total process of plasma separation, metering, mixing, incubation, washing, and detection is fully automated. The analyzer is equipped with an optical detection module to measure absorbances at 10 different wavelengths to accommodate the various kinds of reaction protocols. Compared to the conventional blood analysis done in clinical laboratories, it is advantageous for point-of-care applications because it requires a smaller amount of blood (350 μL <I>vs.</I> 3 mL), takes less time (22 min <I>vs.</I> several days), does not require specially trained operators or expensive instruments to run biochemical analysis and immunoassay separately.</P> <P>Graphic Abstract</P><P>We report a fully integrated lab-on-a-disc system for simultaneous analysis of clinical chemistry and enzyme-linked immuno-sorbent assay (ELISA) from whole blood. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c0lc00205d'> </P>
벌크 비정질 Ni_(57)Ti_(18)Zr_(20)Si₃Sn₂ 입자 산화거동에 따른 HVOF 코팅 상변화 거동
이상용,최한신,김길영,이창희,김용진 대한금속재료학회 2004 대한금속·재료학회지 Vol.42 No.9
Bulk amorphous Ni_(57)Ti_(18) Zr_(20)Si₃Sn₂ feedstock was sprayed using a high velocity oxy-fuel spraying process. In order to evaluate the amorphous formability ign view of chemical instability, the oxygen to hydrogen gas flow rate ratio was changed at the constant total gas flow rate. Flame gas enthalpy was increased with the O₂/H₂ gas ratio. In-flight particle melting state was improved with the increase of oxidizer flow rate. Fthe amorphous phase fraction within an as-sprayed coating was decreased with the oxygen flow rate. From the thermal analysis and x-ray diffraction, the effects of 0₂/H₂ gas ratio on the crystallization of HVOF sprayed bulk amorphous Ni_(57)Ti_(18) Zr_(20)Si₃ could be divided into two categories. One is due to the solid-state crystallization during flight along the low gas enthalpy The other results from the of bulk amorphous feedstock due to the chemical composition change resulting from in-flight particle oxidation at the higher oxygen gas flow rate.
Choi, Hanshin,Byun, Jong Min,Lee, Wonsik,Bang, Su-Ryong,Kim, Young Do The Korean Powder Metallurgy Institute 2016 한국분말재료학회지 (KPMI) Vol.23 No.2
Additive manufacturing (AM) is defined as the manufacture of three-dimensional tangible products by additively consolidating two-dimensional patterns layer by layer. In this review, we introduce four fundamental conceptual pillars that support AM technology: the bottom-up manufacturing factor, computer-aided manufacturing factor, distributed manufacturing factor, and eliminated manufacturing factor. All the conceptual factors work together; however, business strategy and technology optimization will vary according to the main factor that we emphasize. In parallel to the manufacturing paradigm shift toward mass personalization, manufacturing industrial ecology evolves to achieve competitiveness in economics of scope. AM technology is indeed a potent candidate manufacturing technology for satisfying volatile and customized markets. From the viewpoint of the innovation technology adoption cycle, various pros and cons of AM technology themselves prove that it is an innovative technology, in particular a disruptive innovation in manufacturing technology, as powder technology was when ingot metallurgy was dominant. Chasms related to the AM technology adoption cycle and efforts to cross the chasms are considered.