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      • Standardized Breast Cancer Mortality Rate Compared to the General Female Population of Iran

        Haghighat, S.,Akbari, M.E.,Ghaffari, S.,Yavari, P. Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.11

        Introduction: Breast cancer is the most common cancer in women. Improvements of early diagnosis modalities have led to longer survival rates. This study aimed to determine the 5, 10 and 15 year mortality rates of breast cancer patients compared to the normal female population. Materials and Methods: The follow up data of a cohort of 615 breast cancer patients referred to Iranian Breast Cancer Research Center (BCRC) from 1986 to 1996 was considered as reference breast cancer dataset. The dataset was divided into 5 year age groups and the 5, 10 and 15 year probability of death for each group was estimated. The annual mortality rate of Iranian women was obtained from the Death Registry system. Standardized mortality ratios (SMRs) of breast cancer patients were calculated using the ratio of the mortality rate in breast cancer patients over the general female population. Results: The mean age of breast cancer patients at diagnosis time was 45.9 (${\pm}10.5$) years ranging from 24-74. A total of 73, 32 and 2 deaths were recorded at 5, 10 and 15 years, respectively, after diagnosis. The SMRs for breast cancer patients at 5, 10 and 15 year intervals after diagnosis were 6.74 (95% CI, 5.5-8.2), 6.55 (95%CI, 5-8.1) and 1.26 (95%CI, 0.65-2.9), respectively. Conclusion: Results showed that the observed mortality rate of breast cancer patients after 15 years from diagnosis was very similar to expected rates in general female population. This finding would be useful for clinicians and health policy makers to adopt a beneficial strategy to improve breast cancer survival. Further follow-up time with larger sample size and a pooled analysis of survival rates of different centres may shed more light on mortality patterns of breast cancer.

      • Strong, persistent superficial oxidation-assisted chemical bonding of black phosphorus with multiwall carbon nanotubes for high-capacity ultradurable storage of lithium and sodium

        Haghighat-Shishavan, Safa,Nazarian-Samani, Masoud,Nazarian-Samani, Mahboobeh,Roh, Ha-Kyung,Chung, Kyung-Yoon,Cho, Byung-Won,Kashani-Bozorg, Seyed Farshid,Kim, Kwang-Bum The Royal Society of Chemistry 2018 Journal of Materials Chemistry A Vol.6 No.21

        <P>We report a new composite of black phosphorus and multiwall carbon nanotubes (BP-CNT) prepared <I>via</I> a surface oxidation-assisted chemical bonding procedure. The controlled air exposure successfully changed the naturally hydrophobic BP powder to the desired hydrophilicity, which was found indispensable to stable bond formation between the BP and the functionalized CNTs during ball milling. The BP-CNT composites were further fabricated into anodes for both Li- and Na-ion batteries, using a sodium carboxyl methyl cellulose-poly(acrylic acid) (NaCMC-PAA) binary polymeric binder. The hydrophilicity of BP also played a very important role in forming strong bonds with the hydroxyl groups of NaCMC and the carboxylic acid groups of PAA. The plausible mechanisms of stable bond formation were comprehensively examined, and the results revealed two types of strong connections: P-O-C bonds and dehydration cross links. Consequently, the material delivered outstanding electrochemical performance in the anode, with a high discharge capacity of 1681 mA h g<SUP>−1</SUP> after 400 cycles at a current density of 0.2C (1C = 2596 mA g<SUP>−1</SUP>) for Li-ion batteries. It also successfully delivered a first discharge capacity of 2073 and 850 mA h g<SUP>−1</SUP> at 0.2C and 2C for Na-ion batteries, respectively, with excellent capacity retentions at both rates after 200 cycles. These salient results, which originated from the modified hydrophilic BP, will give further impetus to explore BP-based composites for use as high-performance materials for advanced energy storage applications.</P>

      • KCI등재

        Evaluation of Seismic Performance Factors for High-Rise Steel Structures with Diagrid System

        Morteza Sohrabi-Haghighat,Payam Ashtari 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.11

        Diagrid system is a new tubular structural system in tall buildings which requires seismic performance factors (R, Ω0, Cd) for seismic design according to the loading and design codes. By considering the fact that the current codes do not include these factors, this paper aims to evaluate them based on the FEMA P695 methodology. For this purpose, five archetypes have been developed in a way that the structure story heights and span lengths are respectively equal to 4 and 6 meters; this makes the diagonal angles equal to 53.13 degrees. The response modification coefficient (R-factor) of the archetypes was calculated by the Uang method through iteration in analysis and design in OpenSees and ETABS software, respectively. Two types of analysis were carried out: non-linear static analysis (pushover analysis) and non-linear incremental dynamic analysis (IDA); the first evaluates ductility, μT, and over-strength factors, Ω, and the second evaluates “collapse margin ratio (CMR)”. At the end, computed “adjusted collapse margin ratio (ACMR)” was controlled by acceptable values of ACMR in the FEMA P695. Based on the results, the values of R-factor, over-strength factor, Ω0, and deflection amplification factor, Cd, are proposed to be 2.5, 2.0 and 2.5, respectively.

      • KCI등재

        The Effects of Magnesium Supplementation on Serum Magnesium and Calcium Concentration in Patients With Type 2 Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

        Zamani Mohammad,Haghighat Neda 한국임상영양학회 2022 Clinical Nutrition Research Vol.11 No.2

        The aim of this systematic review and meta-analysis was to summarize all the existing randomized controlled trials (RCTs) evidence and to evaluate the effects of magnesium supplementation on serum magnesium, calcium and urinary magnesium concentrations in patients with type 2 diabetes compared with the control. Two independent authors systematically searched online databases including Embase, Scopus, PubMed, and Web of Science from inception until 30th January 2022. RCTs complying with the inclusion criteria were included in this meta-analysis. The heterogeneity among the included studies was assessed using Cochrane’s Q test and I-square (I2) statistic. Data were pooled using a random-effects model and weighted mean difference (WMD) was considered as the overall effect size. Sixteen trials were included in this meta-analysis. Serum magnesium (mean difference, 0.15 mg/dL; 95% confidence interval [CI], 0.06 to 0.23; p = 0.001) and urinary magnesium (WMD, 1.99 mg/dL; 95% CI, 0.36 to 3.62; p = 0.017) concentrations were significantly increased after magnesium supplementation when compared with the control group. However, magnesium supplementation did not have any significant effect on serum calcium (WMD, −0.09 mg/dL; 95% CI, −0.27 to 0.08; p = 0.294) level when compared with the control group. This meta-analysis demonstrated that magnesium supplementation significantly increased Serum magnesium levels which may have played an indirect role in improved clinical symptoms in patients with type 2 diabetes.

      • SCISCIESCOPUS

        Rational hybrid modulation of P, N dual-doped holey graphene for high-performance supercapacitors

        Nazarian-Samani, Masoud,Haghighat-Shishavan, Safa,Nazarian-Samani, Mahboobeh,Kim, Myeong-Seong,Cho, Byung-Won,Oh, Si-Hyoung,Kashani-Bozorg, Seyed Farshid,Kim, Kwang-Bum Elsevier Sequoia 2017 Journal of Power Sources Vol. No.

        <P><B>Abstract</B></P> <P>A P, N dual-doped holey graphene (PNHG) material is prepared by a scalable, facile synthetic approach, using a mixture of glucose, dicyandiamide (DCDA), and phosphoric acid (H<SUB>3</SUB>PO<SUB>4</SUB>). H<SUB>3</SUB>PO<SUB>4</SUB> successfully functions as an “acid catalyst” to encourage the uniform breakage of C=C bonds to create large, localized perforations over the graphene monolith. Further acid treatment and annealing introduce in-plane holes. The correlation between the capacitance of the PNHG and its structural parameters during the fabrication process is comprehensively evaluated. A thermally induced sp<SUP>2</SUP>→sp<SUP>3</SUP> transformation occurs at high temperatures because of the substantial loss of graphitic sp<SUP>2</SUP>-type carbons, together with a dramatic reduction in capacitance. The target PNHG-400 electrode material delivers exceptionally high gravimetric capacitance (235.5 F g<SUP>−1</SUP> at 0.5 A g<SUP>−1</SUP>), remarkable rate capability (84.8% at 70 A g<SUP>−1</SUP>), superior capacitance retention (93.2 and 92.7% at 10 and 50 A g<SUP>−1</SUP> over 25000 cycles, respectively), and acceptable volumetric capacitance due to moderate density, when it is used with organic electrolytes in the voltage range between 0 and 3 V. These results suggest a pioneering defect-engineered strategy to fabricate dual-doped holey graphene with valuable structural properties for high-performance electric double layer supercapacitors, which could be used in next-generation energy storage applications.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Rationally designed P, N dual-doped holey graphene as an electrode in supercapacitors. </LI> <LI> Importance of synergistic ion transport with a high content of C=C bonds. </LI> <LI> Occurrence of sp<SUP>2</SUP>→sp<SUP>3</SUP> transition in graphene structure at temperatures higher than 400 °C. </LI> <LI> High capacitance, excellent rate capability and cyclic stability of the target PNHG-400. </LI> <LI> Novel approach to develop future supercapacitors with high energy and power densities. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>Fabrication of well-designed defect-laden holey graphene counterparts for energy-related applications using a simple, up-scalable and cost-effective strategy.</P> <P>[DISPLAY OMISSION]</P>

      • KCI등재

        Adaptive Resource Management and Provisioning in the Cloud Computing: A Survey of Definitions, Standards and Research Roadmaps

        ( Amin Keshavarzi ),( Abolfazl Toroghi Haghighat ),( Mahdi Bohlouli ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.9

        The fact that cloud computing services have been proposed in recent years, organizations and individuals face with various challenges and problems such as how to migrate applications and software platforms into cloud or how to ensure security of migrated applications. This study reviews the current challenges and open issues in cloud computing, with the focus on autonomic resource management especially in federated clouds. In addition, this study provides recommendations and research roadmaps for scientific activities, as well as potential improvements in federated cloud computing. This survey study covers results achieved through 190 literatures including books, journal and conference papers, industrial reports, forums, and project reports. A solution is proposed for autonomic resource management in the federated clouds, using machine learning and statistical analysis in order to provide better and efficient resource management.

      • KCI등재

        Thiol and urea functionalized magnetic nanoparticles with highly enhanced loading capacity and thermal stability for lipase in transesterification

        Zeinab Salehi,Hamid Haghighat Ghahfarokhi,Abbas Ali Kodadadi,Rasoul Rahimnia 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.35 No.-

        Magnetic nanoparticles (MNPs) were prepared by a co-precipitation method and thiol and ureafunctionalized using (3-mercaptopropyl) trimethoxysilane (MPTS) and 1-(3-trimethoxysilyl propyl)urea (TMSPU). The samples were characterized by SEM, XRD and FTIR, and BET surface areameasurement and used for immobilization of Candida rugosa lipase type VII (CRL7) and Thermomyceslanuginosus lipase (TLL) for a transesterification reaction. The loading capacities of the lipasesimmobilized on the functionalized MNPs were also studied. The activity and thermal stability of theimmobilized lipases were compared to those of the free enzymes too. The loading capacities of CRL7 andTLL on MNPs-TMSPU are 410 and 440 mg/g-MNPs, 5.9 and 5.5 times higher than those on theunfunctionalized MNPs, respectively. The initial activities of both CRL7 and TLL on MNPs-TMSPU arehigher than those on MNPs-MPTS. After 30 min incubation at 80 8C, the remained activity of TLL onMNPs-TMSPU is 2.5 times higher than that of the free enzyme. The remained activities of thebiocomposites assayed after each use in transesterification reaction demonstrate that TLL-MNPs-TMSPUbiocomposite has a high yield of 92%. The immobilized TLL on MNPs-TMSPU and MPTS retain 80% and70% of their initial activities after 8 times reuse, respectively. The functionalized MNPs are magneticallyseparated for reuse.

      • Esophageal, Gastric and Duodenal disorders : Migraine Headache And Peptic Ulcer Diseased In Children

        ( Mohammad Hadi Imanieh ),( Mahrnood Haghighat ),( Seved Mohsen Dehghani ),( Maziyar Irani ),( Maryam Yousefi ),( Davood Mehrabani ) 대한소화기학회 2007 SIDDS Vol.9 No.-

        Background/Aims: Although correlation between migraine headache and GI symptoms were reported, they did not significantly support the correlation between migraine headache and mucosal inflammation or peptic ulcer diseases. This study aimed to find such a correlation. Methods: There were 70 patients (5-15 years old) who had endoscopic documented mucosal inflammation or peptic ulcer diseases. Frequency of migraine headache in this group and a group consisting of a sample of normal population (300) who had not any GI problem in the past year was determined by a questionnaire. Results: The mean age of patients was 10.34 years with male to female ratio of 4:3. Frequency of migraine headache, esophagitis, gastritis, gastric ulcer, duodenitis, and duodenal ulcer was 22.9%, 68.6%, 92.9%, 4.3%, 24.3% and 4.3%, respectively. Regarding frequency of migraine headache among the normal population which was 12.4%, the frequency of migraine headache among patients with mucosal inflammation and peptic ulcer diseases of the upper GI tract, which was 22.9% showed significant statistical correlation. A significant correlation was seen between migraine and esophagitis and also between migraine headache and gastritis. Conclusions: The presence of significant correlation between migraine headache and mucosal inflammation or peptic ulcer diseases of the upper GI tract supports some of precious studies suggested this correlation.

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