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( Oscar Gutierrez Aguirre ),( Angelica Gutierrez Aguirre ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: According to the American Cancer Society, the Non Hodgkin lymphoma (NHL) is one of the most common cancers in the United States of America (EUA), representing 4% of all the cases diagnosed of cancer. The objective of this study is to determine if the number of tons of packed soups consumed in every country has relation with the rate of incidence of NHL. Methods: We use a methodological ecological design. We obtained the rate of incident fi tted by age for country of the data base Globocan of 2012 and the data base of food consumed by country of Euromonitor. The countries included for the analysis are the ones that were found on both data bases. It was analyzed by means, linear regression, coeffi cient of correlation, ANOVA and graphical representation. Results: In total 68 countries fulfi lled the criteria of incorporation. We fi nd a coeffi cient of correlation of 0. 30, in the analysis of variance we fi nd a critical value of F of 7. 00 (p <0. 01). The country with the major consumption of packed soup was E. U. A with 1. 7 million tons, whereas the country with NHL`s with the most incidence was Denmark with rate fi tted by age of 9. 8 cases by every 100, 000 inhabitants. Conclusions: The results suggest that a relation can exist between NHL and the consumption of packed soup. What draws attention are bigger rates of incidence in developed countries than in the developing countries. Nevertheless a limitation of the methodological used design is that it is not possible to determine to individual level the relation between these 2 factors, there will be needed other methodological designs more specifi c to the above mentioned measurement, as cases and controls or cohorts design.
Gutierrez, Bryan,Kwak, Sang-Shin Institute of Electrical and Electronics Engineers 2018 IEEE transactions on power electronics Vol.33 No.11
<P>Model predictive control (MPC) for modular multilevel converter (MMC) systems has drawn attention among researchers in recent years due to its straightforward implementation, ability to control multiple objectives in a single cost function, and excellent dynamic response. Even though MPC seems promising for the MMC, it suffers from an excessive increase in computational complexity when the number of submodules (SMs) per arm (<I>N</I>) is increased. The computational load can be reduced by decoupling the SM capacitor voltage control from the cost function and balancing them in an external voltage sorting algorithm. In this paper, a further reduction of computations in the MPC is achieved by the preselection of control options that can satisfy the control objectives in the next sampling time. The preselection algorithm generates a greatly reduced number of control options to be computed by a straightforward MPC loop at each sampling time. In addition, the MPC together with the preselection algorithm can generate <TEX>$2N+ 1$</TEX> output voltage levels in the MMC while maintaining a low <TEX>$dv/ dt$</TEX> in the output voltage and suppressing the circulating currents in MMCs with considerable number of SMs. The steady-state and dynamic performance of the MMC operating with the proposed method is verified by simulation and experimental results.</P>
Comparison and Study of Active and Hybrid Power Filters for Compensation of Grid Harmonics
Gutierrez, Bryan,Kwak, Sang-Shin The Korean Institute of Power Electronics 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.4
This paper presents a theoretical analysis and comparisons of active power filter (APF) and hybrid power filter (HPF) systems, given terminal constraints of harmonic compensations in nonlinear loads. Despite numerous publications for the two types of filters, the features and differences between them have not been clearly explained. This paper presents a detailed analysis of the operations of a HPF inverter along with those of passive power filters (PPFs). It also includes their effects on the power factor at the grid. In addition, a theoretical analysis and a systematic comparison between the APF and HPF systems are addressed based on system parameters such as the source voltage, output power, reactive component size, and power factor at the grid terminals. The converter kVA ratings and dc-link voltage requirements for both topologies are considered in the presented comparisons
Gutierrez-Malacatt, Humberto,Ayala-Sanchez, Manuel,Aquino-Ortega, Xochitl,Dominguez-Rodriguez, Jacqueline,Martinez-Tovar, Adolfo,Olarte-Carrillo, Irma,Martinez-Hernandez, Angelica,Cecilia, Contreras-C Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.4
Background: Chronic myeloid leukemia (CML) is one of the most frequent hematopoietic malignancies in the elderly population; however, knowledge is limited regarding the genetic factors associated with increased risk for CML. Polymorphisms affecting microRNA (miRNA) biogenesis or mRNA:miRNA interactions are important risk factors in the development of different types of cancer. Thus, we carried out a case-control study to test the association with CML susceptibility of gene variants located in the miRNA machinery genes AGO1 (rs636832) and GEMIN4 (rs2740348), as well as in the miRNA binding sites of the genes BRCA1 (rs799917) and KRAS (rs61764370). Materials and Methods: We determined the genotype of 781 Mexican-Mestizo individuals (469 healthy subjects and 312 CML cases) for the four polymorphisms using TaqMan probes to test the association with CML susceptibility. Results: We found a borderline association of the minor homozygote genotype of the KRAS_rs61764370 polymorphism with an increased risk for CML susceptibility (P = 0.06). After gender stratification, this association was significant only for women (odds ratio [OR] = 13.41, P = 0.04). The distribution of the allelic and genotypic frequencies of the four studied SNPs was neither associated with advanced phases of CML nor treatment response. Conclusions: To the best of our knowledge, this study is the first to show a significant association of the KRAS_rs61764370 SNP with CML. To further determine such an association of with CML susceptibility, our results must be replicated in different ethnic groups.
Gutierrez-Vargas, Gildardo,Ruiz, Alberto,Lopez-Morelos, Victor H.,Kim, Jin-Yeon,Gonzalez-Sanchez, Jorge,Medina-Flores, Ariosto Korean Nuclear Society 2021 Nuclear Engineering and Technology Vol.53 No.9
One of the consequences of the 475 ℃ embrittlement of duplex stainless steels is the reduction of the resistance to localized corrosion. Therefore, the detection of this type of embrittlement before the material exhibits significant loss in toughness, and corrosion resistance is important to ensure the structural integrity of critical components under corrosion threats. In this research, conductivity measurements are performed using the alternating current potential drop (ACPD) technique with using a portable four-point probe as a nondestructive evaluation (NDE) method for detecting the embrittlement in a 2507 (UNS S32750) super duplex stainless steel (SDSS) aged at 475 ℃ from as-received condition to 300 h. The electric conductivity results were compared against two electrochemical tests namely double loop electrochemical potentiokinetic reactivation (DL-EPR) and critical pitting temperature (CPT). Mechanical tests and the microstructure characterized using scanning electron microscopy (SEM) imaging are conducted to track the progress of embrittlement. It is shown that the electric conductivity correlates with the changes in impact energy, microhardness, and CPT corrosion tests result demonstrating the feasibility of the four-point probe as a possible field-deployable method for evaluating the 475 ℃ embrittlement of 2507 SDSS.
The role of the transcription factor ETV5 in insulin exocytosis.
Gutierrez-Aguilar, Ruth,Kim, Dong-Hoon,Casimir, Marina,Dai, Xiao-Qing,Pfluger, Paul T,Park, Jongsun,Haller, April,Donelan, Elizabeth,Park, Jisoo,D'Alessio, David,Woods, Stephen C,MacDonald, Patrick E Springer Verlag 2014 Diabetologia Vol.57 No.2
<P>Genome-wide association studies have revealed an association of the transcription factor ETS variant gene 5 (ETV5) with human obesity. However, its role in glucose homeostasis and energy balance is unknown.</P>
An Adaptive and Real-Time System for the Analysis and Design of Underground Constructions
Gutierrez, Marte Korean Geotechnical Society 2010 지반 : 한국지반공학회지 Vol.26 No.9
Underground constructions continue to provide challenges to Geotechnical Engineers yet they pose the best opportunities for development and deployment of advance technologies for analysis, design and construction. The reason for this is that, by virtue of the nature of underground constructions, more data and information on ground characteristics and response become available as the construction progresses. However, due to several barriers, these data and information are rarely, if ever, utilized to modify and improve project design and construction during the construction stage. To enable the use of evolving realtime data and information, and adaptively modify and improve design and construction, the paper presents an analysis and design system, called AMADEUS, for underground projects. AMADEUS stands for Adaptive, real-time and geologic Mapping, Analysis and Design of Underground Space. AMADEUS relies on recent advances in IT (Information Technology), particularly in digital imaging, data management, visualization and computation to significantly improve analysis, design and construction of underground projects. Using IT and remote sensors, real-time data on geology and excavation response are gathered during the construction using non-intrusive techniques which do not require expensive and time-consuming monitoring. The real-time data are then used to update geological and geomechanical models of the excavation, and to determine the optimal, construction sequences and stages, and structural support. Virtual environment (VE) systems are employed to allow virtual walk-throughs inside an excavation, observe geologic conditions, perform virtual construction operations, and investigate stability of the excavation via computer simulation to steer the next stages of construction.
Gutierrez, Janitza Nicole Punto,Lee, Kilhung Korea Multimedia Society 2020 The journal of multimedia information system Vol.7 No.2
Nowadays, cloud computing is becoming more popular among companies. However, the characteristics of cloud computing such as a virtualized environment, constantly changing, possible to modify easily and multi-tenancy with a distributed nature, it is difficult to perform attack detection with traditional tools. This work proposes a solution which aims to collect traffic packets data by using Flume and filter them with Spark Streaming so it is possible to only consider suspicious data related to HTTP Slow Rate Denial-of-Service attacks and reduce the data that will be stored in Hadoop Distributed File System for analysis with the FP-Growth algorithm. With the proposed system, we also aim to address the difficulties in attack detection in cloud environment, facilitating the data collection, reducing detection time and enabling an almost real-time attack detection.