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The role of the transcription factor ETV5 in insulin exocytosis.
Gutierrez-Aguilar, Ruth,Kim, Dong-Hoon,Casimir, Marina,Dai, Xiao-Qing,Pfluger, Paul T,Park, Jongsun,Haller, April,Donelan, Elizabeth,Park, Jisoo,D'Alessio, David,Woods, Stephen C,MacDonald, Patrick E Springer Verlag 2014 Diabetologia Vol.57 No.2
<P>Genome-wide association studies have revealed an association of the transcription factor ETS variant gene 5 (ETV5) with human obesity. However, its role in glucose homeostasis and energy balance is unknown.</P>
Catechin Degradation by Several Fungal Strains Isolated from Mexican Desert
AGUILAR, CRISTO´BAL NOE´,CRUZ, MARIO,RODRI´GUEZ, RAUL,GUTIERREZ-SA´NCHEZ,GERARDO,RAMIREZ-CORONEL, ASCENCIO´N,AUGUR, CHRISTOPHER 한국미생물 · 생명공학회 2004 Journal of microbiology and biotechnology Vol.14 No.2
Eleven fungal strains previously isolated from the Mexican desert were evaluated for their capacity to use catechin as carbon source in submerged cultures. At 2 g/l of catechin, all strains grew better than the control strains, Aspergillus niger Aa-20. Aspergillus niger PSH and Penicillium commune EH2 degraded 79.33% and 76.35% with degradation rates of 0.0065 and 0.0074g/I/h, respectively, when an initial catechin concentration of 3 g/l was used. Obtained results demonstrated the potential biotechnological capacity of these fungal strains to use condensed tannins as carbon source.
M.E. Rivas-Aguilar,N. Hernandez-Como,G. Gutierrez-Heredia,A. Sánchez-Martínez,M. Mireles Ramirez,M.A. Quevedo-López 한국물리학회 2018 Current Applied Physics Vol.18 No.7
In this work, the specific contact resistance (ρc) between amorphous indium-gallium-zinc-oxide (IGZO) semiconductor and different contact electrodes was obtained from thin film transistors (TFTs). Ti/Au (10/100 nm), aluminum doped zinc oxide (AZO, 100 nm) and indium tin oxide (ITO, 100 nm) were used as source/drain electrodes to fabricate IGZO TFTs. Chemical states of the contacts/semiconductor interfaces were examined by depth profile X-ray photoelectron spectroscopy (XPS) analysis to explain the origin of the differences on specific contact resistance. The lowest ρc achieved using Ti/Au was related to the formation of a TiOx interlayer due to oxygen atoms diffusing out from the semiconductor under layer, increasing the carrier concentration of IGZO at the interface and lowering the ρc. On the contrary, no interfacial reactions were observed between IGZO and AZO or ITO source/drain. However, IGZO resistivity increased with ITO contacts likely due to oxygen vacancies filling during ITO deposition. This fact seems to be the origin of the high contact resistance between IGZO and ITO, compared to IGZO-AZO and IGZO-Ti/Au interfaces.
Salcedo, Mauricio,Pina-Sanchez, Patricia,Vallejo-Ruiz, Veronica,Monroy-Garcia, Alberto,Aguilar-Lemarroy, Adriana,Cortes-Gutierrez, Elva I.,Santos-Lopez, Gerardo,Montoya-Fuentes, Hector,Grijalva, Renan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23
Background: The aetiological relationship between human papillomavirus (HPV) infection and cervical cancer (CC) is widely accepted. Our goal was to determine the prevalence of HPV types in Mexican women attending at the Mexican Institute for Social Security from different areas of Mexico. Materials and Methods: DNAs from 2,956 cervical samples were subjected to HPV genotyping: 1,020 samples with normal cytology, 931 with low-grade squamous intraepithelial lesions (LGSIL), 481 with high grade HGSIL and 524 CC. Results: Overall HPV prevalence was 67.1%. A total of 40 HPV types were found; HPV16 was detected in 39.4% of the HPV-positive samples followed by HPV18 at 7.5%, HPV31 at 7.1%, HPV59 at 4.9%, and HPV58 at 3.2%. HPV16 presented the highest prevalence both in women with altered or normal cytology and HPV 18 presented a minor prevalence as reported worldwide. The prevalence ratio (PR) was calculated for the HPV types. The analysis of PR showed that HPV16 presents the highest association with CC, HPV 31, -33, -45, -52 and -58 also demonstrating a high association. Conclusions: The most prevalent HPV types in cervical cancer samples were -16, -18, -31, but it is important to note that we obtained a minor prevalence of HPV18 as reported worldwide, and that HPV58 and -52 also were genotypes with an important prevalence in CC samples. Determination of HPV genotypes is very important in order to evaluate the impact of vaccine introduction and future cervical cancer prevention strategies.